Description
Experimental Technique/Method:X-RAY DIFFRACTION
Resolution:3.0
Classification:ISOMERASE
Release Date:2000-10-14
Deposition Date:1999-10-14
Revision Date:2008-04-27#2011-07-13
Molecular Weight:73322.78
Macromolecule Type:Protein
Residue Count:653
Atom Site Count:4798
DOI:10.2210/pdb1d6m/pdb
Abstract:
DNA topoisomerases are enzymes that change the topology of DNA. Type IA topoisomerases transiently cleave one DNA strand in order to pass another strand or strands through the break. In this manner, they can relax negatively supercoiled DNA and catenate and decatenate DNA molecules. Structural information on Escherichia coli DNA topoisomerase III is important for understanding the mechanism of this type of enzyme and for studying the mechanistic differences among different members of the same subfamily.
Resolution:3.0
Classification:ISOMERASE
Release Date:2000-10-14
Deposition Date:1999-10-14
Revision Date:2008-04-27#2011-07-13
Molecular Weight:73322.78
Macromolecule Type:Protein
Residue Count:653
Atom Site Count:4798
DOI:10.2210/pdb1d6m/pdb
Abstract:
DNA topoisomerases are enzymes that change the topology of DNA. Type IA topoisomerases transiently cleave one DNA strand in order to pass another strand or strands through the break. In this manner, they can relax negatively supercoiled DNA and catenate and decatenate DNA molecules. Structural information on Escherichia coli DNA topoisomerase III is important for understanding the mechanism of this type of enzyme and for studying the mechanistic differences among different members of the same subfamily.
| Date made available | 2000 |
|---|---|
| Publisher | RCSB-PDB |