Description
Experimental Technique/Method:X-RAY DIFFRACTION
Resolution:1.6
Classification:DNA BINDING
Release Date:1996-03-08
Deposition Date:1995-10-02
Revision Date:2008-03-24#2011-07-13
Molecular Weight:9066.25
Macromolecule Type:Protein
Residue Count:77
Atom Site Count:640
DOI:10.2210/pdb1vcc/pdb
Abstract:
Vaccinia virus, a cytoplasmically-replicating poxvirus, encodes a type I DNA topoisomerase that is biochemically similar to eukaryotic-like DNA topoisomerases I, and which has been widely studied as a model topoisomerase. It is the smallest topoisomerase known and is unusual in that it is resistant to the potent chemotherapeutic agent camptothecin.
Resolution:1.6
Classification:DNA BINDING
Release Date:1996-03-08
Deposition Date:1995-10-02
Revision Date:2008-03-24#2011-07-13
Molecular Weight:9066.25
Macromolecule Type:Protein
Residue Count:77
Atom Site Count:640
DOI:10.2210/pdb1vcc/pdb
Abstract:
Vaccinia virus, a cytoplasmically-replicating poxvirus, encodes a type I DNA topoisomerase that is biochemically similar to eukaryotic-like DNA topoisomerases I, and which has been widely studied as a model topoisomerase. It is the smallest topoisomerase known and is unusual in that it is resistant to the potent chemotherapeutic agent camptothecin.
| Date made available | 1996 |
|---|---|
| Publisher | RCSB-PDB |