5FSA : Crystal structure of sterol 14-alpha demethylase (CYP51) from a pathogenic yeast Candida albicans in complex with the antifungal drug posaconazole

  • Tatiana Y. Hargrove (Contributor)
  • Laura Friggeri (Contributor)
  • Zdzislaw Wawrzak (Contributor)
  • Galina I. Lepesheva (Contributor)

Dataset

Description

Experimental Technique/Method:X-RAY DIFFRACTION
Resolution:2.86
Classification:OXIDOREDUCTASE
Release Date:2017-03-15
Deposition Date:2016-01-02
Revision Date:2017-03-22#2017-05-03
Molecular Weight:115504.91
Macromolecule Type:Protein
Residue Count:980
Atom Site Count:8036
DOI:10.2210/pdb5fsa/pdb

Abstract:
With some advances in modern medicine (such as cancer chemotherapy, broad exposure to antibiotics, and immunosuppression), the incidence of opportunistic fungal pathogens such as
Date made available2017
PublisherRCSB-PDB

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