Additional file 1 of Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice

Additional file 1: Supplementary Fig. 1. Chronic treatment with FTI LNK-754 reduces amyloid burden in the brains of 5XFAD mice. Confocal immunofluorescence microscopy showing uncropped images from Fig. 1A of brain sections from 5-month-old 5XFAD mice treated with vehicle, LNK-754 or lonafarnib immunostained for Aβ42 (red) and NeuN (blue). Scale bar, 1000 μm