Additional file 3: Figure S3. of Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development

miR-135a bioinformatics analysis. A) Top pathways targeted by miR-135a. TGFβ/BMP and Wnt signaling pathways rank at position number 2 and 3 with high statistical significance. P values and number of genes targeted in each pathway are indicated. B) Overview of TGFβ/BMP cascade with highlighted, and listed, 16 genes targeted by miR-135a. It is worth noticing that the number of listed genes reflects only the data available on the Diana web site and the algorithm used for the search, as a higher number of putative miR-135a targets have already been reported using multiple search engines [11]. (TIF 1865 kb)