Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator

Jianbin Zheng (Contributor)
Long Chen (Contributor)
Owen S. Skinner (Contributor)
Daniel Ysselstein (Contributor)
Jonathan Remis (Contributor)
Peter Lansbury (Contributor)
Renato Skerlj (Contributor)
Michael Mrosek (Contributor)
Ursula Heunisch (Contributor)
Stephan Krapp (Contributor)
Joel Charrow (Contributor)
Michael Schwake (Contributor)
Neil L Kelleher (Contributor)
Richard B Silverman (Contributor)
Dimitri Krainc (Contributor)

Dataset

Date made available	Oct 25 2017
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb5LVX/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00005lvx

1 Article

β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site
Zheng, J., Chen, L., Skinner, O. S., Ysselstein, D., Remis, J., Lansbury, P., Skerlj, R., Mrosek, M., Heunisch, U., Krapp, S., Charrow, J., Schwake, M., Kelleher, N. L., Silverman, R. B. & Krainc, D., May 9 2018, In: Journal of the American Chemical Society. 140, 18, p. 5914-5924 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
38 Scopus citations

Cite this

Zheng, J. (Contributor), Chen, L. (Contributor), Skinner, O. S. (Contributor), Ysselstein, D. (Contributor), Remis, J. (Contributor), Lansbury, P. (Contributor), Skerlj, R. (Contributor), Mrosek, M. (Contributor), Heunisch, U. (Contributor), Krapp, S. (Contributor), Charrow, J. (Contributor), Schwake, M. (Contributor), Kelleher, N. L. (Contributor), Silverman, R. B. (Contributor), Krainc, D. (Contributor) (Oct 25 2017). Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator. Protein Data Bank (PDB). 10.2210/pdb5LVX/pdb

Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator

DOI

Access Dataset

Research output

β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site

Cite this