Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove.

Monica Rosas-Lemus (Contributor)
George Minasov (Contributor)
Ludmilla A Shuvalova (Contributor)
Nicole L. Inniss (Contributor)
Olga Kiryukhina (Contributor)
Joseph Brunzelle (Contributor)
Karla J Satchell (Contributor)

Dataset

Date made available	May 13 2020
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb6WRZ/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00006wrz

1 Article

High-resolution structures of the SARS-CoV-2 2′-O-methyltransferase reveal strategies for structure-based inhibitor design
Rosas-Lemus, M., Minasov, G., Shuvalova, L., Inniss, N. L., Kiryukhina, O., Brunzelle, J. & Satchell, K. J. F., Sep 29 2020, In: Science Signaling. 13, 651, eabe1202.
Research output: Contribution to journal › Article › peer-review

Open Access
147 Scopus citations

Cite this

Rosas-Lemus, M. (Contributor), Minasov, G. (Contributor), Shuvalova, L. (Contributor), Inniss, N. L. (Contributor), Kiryukhina, O. (Contributor), Brunzelle, J. (Contributor), Satchell, K. J. F. (Contributor) (May 13 2020). Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove. Protein Data Bank (PDB). 10.2210/pdb6WRZ/pdb

Crystal Structure of Nsp16-Nsp10 Heterodimer from SARS-CoV-2 with 7-methyl-GpppA and S-adenosyl-L-homocysteine in the Active Site and Sulfates in the mRNA Binding Groove.

DOI

Access Dataset

Research output

High-resolution structures of the SARS-CoV-2 2′-O-methyltransferase reveal strategies for structure-based inhibitor design

Cite this