Crystal structure of p38 alpha MAP kinase in complex with a novel isoform selective drug candidate

Saktimayee Mitra Roy (Contributor)
Valerie L. Grum-Tokars (Contributor)
James P. Schavocky (Contributor)
Faisal Saeed (Contributor)
Agnieszka Staniszewski (Contributor)
Andrew F. Teich (Contributor)
Ottavio Arancio (Contributor)
Adam D. Bachstetter (Contributor)
Scott J. Webster (Contributor)
Linda J. van Eldik (Contributor)
George Minasov (Contributor)
Wayne F Anderson (Contributor)
Jeffrey C. Pelletier (Contributor)
Daniel M Watterson (Contributor)

Dataset

Date made available	Feb 25 2015
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb4R3C/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00004r3c

1 Article

Targeting Human Central Nervous System Protein Kinases: An Isoform Selective p38αMAPK Inhibitor That Attenuates Disease Progression in Alzheimer's Disease Mouse Models
Roy, S. M., Grum-Tokars, V. L., Schavocky, J. P., Saeed, F., Staniszewski, A., Teich, A. F., Arancio, O., Bachstetter, A. D., Webster, S. J., Van Eldik, L. J., Minasov, G., Anderson, W. F., Pelletier, J. C. & Watterson, D. M., Apr 15 2015, In: ACS Chemical Neuroscience. 6, 4, p. 666-680 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
75 Scopus citations

Cite this

Roy, S. M. (Contributor), Grum-Tokars, V. L. (Contributor), Schavocky, J. P. (Contributor), Saeed, F. (Contributor), Staniszewski, A. (Contributor), Teich, A. F. (Contributor), Arancio, O. (Contributor), Bachstetter, A. D. (Contributor), Webster, S. J. (Contributor), Van Eldik, L. J. (Contributor), Minasov, G. (Contributor), Anderson, W. F. (Contributor), Pelletier, J. C. (Contributor), Watterson, D. M. (Contributor) (Feb 25 2015). Crystal structure of p38 alpha MAP kinase in complex with a novel isoform selective drug candidate. Protein Data Bank (PDB). 10.2210/pdb4R3C/pdb

Crystal structure of p38 alpha MAP kinase in complex with a novel isoform selective drug candidate

DOI

Access Dataset

Research output

Targeting Human Central Nervous System Protein Kinases: An Isoform Selective p38αMAPK Inhibitor That Attenuates Disease Progression in Alzheimer's Disease Mouse Models

Cite this