Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and two Magnesium (Mg) ions.

George Minasov (Contributor)
Monica Rosas-Lemus (Contributor)
Ludmilla A Shuvalova (Contributor)
Nicole L. Inniss (Contributor)
Joseph S. Brunzelle (Contributor)
Courtney M. Daczkowski (Contributor)
Paul J. Hoover (Contributor)
Andrew D. Mesecar (Contributor)
Karla J Satchell (Contributor)

Dataset

Date made available	Jan 6 2021
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb7L6T/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00007l6t

1 Article

Mn²⁺ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16
Minasov, G., Rosas-Lemus, M., Shuvalova, L., Inniss, N. L., Brunzelle, J. S., Daczkowski, C. M., Hoover, P., Mesecar, A. D. & Satchell, K. J. F., Jun 29 2021, In: Science Signaling. 14, 689, eabh2071.
Research output: Contribution to journal › Article › peer-review

Open Access
19 Scopus citations

Cite this

Minasov, G. (Contributor), Rosas-Lemus, M. (Contributor), Shuvalova, L. (Contributor), Inniss, N. L. (Contributor), Brunzelle, J. S. (Contributor), Daczkowski, C. M. (Contributor), Hoover, P. (Contributor), Mesecar, A. D. (Contributor), Satchell, K. J. F. (Contributor) (Jan 6 2021). Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and two Magnesium (Mg) ions. Protein Data Bank (PDB). 10.2210/pdb7L6T/pdb

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and two Magnesium (Mg) ions.

DOI

Access Dataset

Research output

Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16

Cite this

Mn²⁺ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16