Crystal structure of sterol 14alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with an inhibitor VNF ((4-(4-chlorophenyl)-N-[2-(1H-imidazol-1-yl)-1-phenylethyl]benzamide)

Galina I. Lepesheva (Contributor)
Tatiana Y. Hargrove (Contributor)
Spencer M Anderson (Contributor)
Yuliya Kleshchenko (Contributor)
Vyacheslav Furtak (Contributor)
Zdzislaw Wawrzak (Contributor)
Fernando Villalta (Contributor)
Michael R. Waterman (Contributor)

Dataset

Date made available	Dec 1 2009
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb3KSW/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00003ksw

1 Article

Structural insights into inhibition of sterol 14α-demethylase in the human pathogen Trypanosoma cruzi
Lepesheva, G. I., Hargrove, T. Y., Anderson, S., Kleshchenko, Y., Furtak, V., Wawrzak, Z., Villalta, F. & Waterman, M. R., Aug 13 2010, In: Journal of Biological Chemistry. 285, 33, p. 25582-25590 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
137 Scopus citations

Cite this

Lepesheva, G. I. (Contributor), Hargrove, T. Y. (Contributor), Anderson, S. (Contributor), Kleshchenko, Y. (Contributor), Furtak, V. (Contributor), Wawrzak, Z. (Contributor), Villalta, F. (Contributor), Waterman, M. R. (Contributor) (Dec 1 2009). Crystal structure of sterol 14alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with an inhibitor VNF ((4-(4-chlorophenyl)-N-[2-(1H-imidazol-1-yl)-1-phenylethyl]benzamide). Protein Data Bank (PDB). 10.2210/pdb3KSW/pdb

Crystal structure of sterol 14alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with an inhibitor VNF ((4-(4-chlorophenyl)-N-[2-(1H-imidazol-1-yl)-1-phenylethyl]benzamide)

DOI

Access Dataset

Research output

Structural insights into inhibition of sterol 14α-demethylase in the human pathogen Trypanosoma cruzi

Cite this