Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution.

Lina Juknaitě (Contributor)
Yutaro Sugamata (Contributor)
Kazuya Tokiwa (Contributor)
Yuichi Ishikawa (Contributor)
Satoshi Takamizawa (Contributor)
Andrew Eng (Contributor)
Ryuichi Sakai (Contributor)
Darryl S. Pickering (Contributor)
Karla Frydenvang (Contributor)
Geoffrey T Swanson (Contributor)
Jette S. Kastrup (Contributor)
Masato Oikawa (Contributor)

Dataset

Date made available	Mar 20 2013
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb4ISU/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00004isu

1 Article

Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: Asymmetric synthesis, neuroactivity, and structural characterization
Juknaitě, L., Sugamata, Y., Tokiwa, K., Ishikawa, Y., Takamizawa, S., Eng, A., Sakai, R., Pickering, D. S., Frydenvang, K., Swanson, G. T., Kastrup, J. S. & Oikawa, M., Mar 28 2013, In: Journal of Medicinal Chemistry. 56, 6, p. 2283-2293 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
25 Scopus citations

Cite this

Juknaitě, L. (Contributor), Sugamata, Y. (Contributor), Tokiwa, K. (Contributor), Ishikawa, Y. (Contributor), Takamizawa, S. (Contributor), Eng, A. (Contributor), Sakai, R. (Contributor), Pickering, D. S. (Contributor), Frydenvang, K. (Contributor), Swanson, G. T. (Contributor), Kastrup, J. S. (Contributor), Oikawa, M. (Contributor) (Mar 20 2013). Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution. Protein Data Bank (PDB). 10.2210/pdb4ISU/pdb

Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the antagonist (2R)-IKM-159 at 2.3A resolution.

DOI

Access Dataset

Research output

Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: Asymmetric synthesis, neuroactivity, and structural characterization

Cite this