Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with Compound 5a bound to the Cryptic Pocket of nsp16

Nicole L. Inniss (Contributor)
Ján Kozic (Contributor)
Fengling Li (Contributor)
Monica Rosas-Lemus (Contributor)
George Minasov (Contributor)
Jiří Rybáček (Contributor)
Yingjie Zhu (Contributor)
Radek Pohl (Contributor)
Ludmilla A Shuvalova (Contributor)
Lubomír Rulíšek (Contributor)
Joseph S. Brunzelle (Contributor)
Lucie Bednárová (Contributor)
Milan Štefek (Contributor)
Ján Michael Kormaník (Contributor)
Erik Andris (Contributor)
Jaroslav Šebestík (Contributor)
Alice Shi Ming Li (Contributor)
Peter J. Brown (Contributor)
Uli Schmitz (Contributor)
Kumar Saikatendu (Contributor)
Edcon Chang (Contributor)
Radim Nencka (Contributor)
Masoud Vedadi (Contributor)
Karla J Satchell (Contributor)

Dataset

Date made available	Oct 18 2023
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb8F4S/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00008f4s

1 Article

Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors
Inniss, N. L., Kozic, J., Li, F., Rosas-Lemus, M., Minasov, G., Rybáček, J., Zhu, Y., Pohl, R., Shuvalova, L., Rulíšek, L., Brunzelle, J. S., Bednárová, L., Štefek, M., Kormaník, J. M., Andris, E., Šebestík, J., Li, A. S. M., Brown, P. J., Schmitz, U. & Saikatendu, K. & 4 others, Chang, E., Nencka, R., Vedadi, M. & Satchell, K. J. F., Oct 13 2023, In: ACS Infectious Diseases. 9, 10, p. 1918-1931 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
7 Scopus citations

Cite this

Inniss, N. L. (Contributor), Kozic, J. (Contributor), Li, F. (Contributor), Rosas-Lemus, M. (Contributor), Minasov, G. (Contributor), Rybáček, J. (Contributor), Zhu, Y. (Contributor), Pohl, R. (Contributor), Shuvalova, L. (Contributor), Rulíšek, L. (Contributor), Brunzelle, J. S. (Contributor), Bednárová, L. (Contributor), Štefek, M. (Contributor), Kormaník, J. M. (Contributor), Andris, E. (Contributor), Šebestík, J. (Contributor), Li, A. S. M. (Contributor), Brown, P. J. (Contributor), Schmitz, U. (Contributor), Saikatendu, K. (Contributor), Chang, E. (Contributor), Nencka, R. (Contributor), Vedadi, M. (Contributor), Satchell, K. J. F. (Contributor) (Oct 18 2023). Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with Compound 5a bound to the Cryptic Pocket of nsp16. Protein Data Bank (PDB). 10.2210/pdb8F4S/pdb

Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with Compound 5a bound to the Cryptic Pocket of nsp16

DOI

Access Dataset

Research output

Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors

Cite this