Higher hydroxyurea adherence among young adults with sickle cell disease compared to children and adolescents

  • Paavani Reddy (Creator)
  • Stephanie W. Cai (Creator)
  • Leonardo Barrera (Creator)
  • Kathryn King (Creator)
  • Sherif M Badawy (Creator)



Sickle cell disease (SCD) results in severe complications, such as anaemia and pain episodes. Hydroxyurea (HU) is efficacious in SCD, yet adherence remains low. To assess the relationship of HU adherence to health care utilization and patients’ characteristics. This is a 5-year retrospective chart review. Patients’ demographics and medical history were collected from the electronic medical record (EMR). HU adherence was evaluated using foetal haemoglobin “HbF%”, mean corpuscular volume “MCV”, and absolute neutrophil count “ANC”. Age groups included children (
Date made available2022
PublisherTaylor & Francis

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