MOESM1 of A metastable subproteome underlies inclusion formation in muscle proteinopathies

  • Prajwal Ciryam (Contributor)
  • Matthew Antalek (Creator)
  • Fernando Cid (Creator)
  • GianGaetano Tartaglia (Creator)
  • C. M. Dobson (Creator)
  • Anne Katrin Guettsches (Contributor)
  • Britta Eggers (Creator)
  • Matthias Vorgerd (Creator)
  • Katrin Marcus (Creator)
  • Rudolf A. Kley (Creator)
  • Richard I Morimoto (Creator)
  • Michele Vendruscolo (Creator)
  • Conrad C. Weihl (Creator)

Dataset

Description

Additional file 1: Dataset S1. Proteins enriched in rimmed vacuoles. Dataset S2. Proteins enriched in plaques, neurofibrillary tangles, and protein aggregation myopathies. Dataset S3. Aggregation propensity scores. Zagg, ZaggSC$$ {Z}_{agg}^{SC} $$, and TANGO scores (4) calculated as described in Methods. Dataset S4. mRNA expression levels. Dataset S5. Hereditary protein aggregation myopathy abundance data. Dataset S6. Sporadic inclusion body myositis abundance data. Dataset S7. Unfolded supersaturation scores. Dataset S8. Hereditary protein aggregation myopathy supersaturation scores (σf). Dataset S9. Sporadic inclusion body myositis supersaturation scores (σf). Dataset S10. Sporadic inclusion body myositis supersaturation scores (σfT$$ {\sigma}_f^T $$). Dataset S11. Upregulated and downregulated proteins in sporadic inclusion body myositis. Dataset S12. Summary of statistical analysis and families of statistical tests.
Date made available2019
Publisherfigshare

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