MOESM2 of Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study

  • Sarah H. White (Creator)
  • Mary M McDermott (Creator)
  • Robert L Sufit (Creator)
  • Kate Kosmac (Creator)
  • Alex W. Bugg (Creator)
  • Marta Gonzalez-Freire (Creator)
  • Luigi Ferrucci (Creator)
  • Lu Tian (Creator)
  • Lihui Zhao (Contributor)
  • Ying Gao (Creator)
  • Melina R. Kibbe (Northwestern University, Department of Veterans Affairs) (Creator)
  • Michael H. Criqui (Creator)
  • Christiaan Leeuwenburgh (Creator)
  • Charlotte A. Peterson (Creator)
  • Mary M. McDermott (Creator)
  • Luigi Ferrucci (Creator)
  • Michael H. Criqui (Creator)



Additional file 2: Figure S2. Whisker plot of the fiber type analysis of gastrocnemius muscle using isoform-specific myosin heavy chain (MyHC) immunohistochemistry. The distribution of type I, type IIa, and type IIa/x fibers is shown for non-PAD (n=7) and PAD (n=26) subjects. Approximately 1000 fibers were analyzed per subject.
Date made available2016

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