Overactive bladder in an integrated delivery system: a longitudinal cohort study

  • Jeffrey A Linder MD MPH (Creator)
  • Joel S. Weissman (Creator)
  • Harry Reyes Nieva (Contributor)
  • Stuart Lipsitz (Creator)
  • R. Sterling Haring (Contributor)
  • Julie Deangelis (Contributor)
  • Rita M. Kristy (Creator)
  • Kevin R. Loughlin (Creator)



Abstract Background Overactive bladder (OAB) is common and morbid. Medication and diagnosis claims may be specific, but lack sensitivity to identify patients with overactive bladder. We used an “electronic health record (EHR) phenotype” to identify cases and describe treatment choices and anticholinergic burden for OAB. Methods We conducted a retrospective cohort study in a large, integrated health delivery system between July 2011 and June 2012 (2-year follow-up). We examined care from primary care and specialty clinics, medication and procedure use, and anticholinergic burden for each patient. Results There were 7362 patients with an EHR OAB phenotype; 50% of patients were > 65 years old, 74% were female, and 83% were white. The distribution of care included primary care physician (PCP)/specialty co-management (25% of patients); PCP care only (18%); urology only (13%); or some other combination of specialty care (33%). Only 40% of patients were prescribed at least 1 OAB medication during the study. The mean duration of prescribed medication was 1.5 months (95% confidence interval [CI], 1.4 to 1.6 months; range,
Date made available2020

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