Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine

Ha T. Do (Contributor)
Huiying Li (Contributor)
Georges Chreifi (Contributor)
Thomas L. Poulos (Contributor)
Richard B Silverman (Contributor)

Dataset

Date made available	Mar 13 2019
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb6NHC/pdb

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https://www.wwpdb.org/pdb?id=pdb_00006nhc

1 Article

Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold
Do, H. T., Li, H., Chreifi, G., Poulos, T. L. & Silverman, R. B., Mar 14 2019, In: Journal of Medicinal Chemistry. 62, 5, p. 2690-2707 18 p.
Research output: Contribution to journal › Article › peer-review

Open Access
31 Scopus citations

Cite this

Do, H. T. (Contributor), Li, H. (Contributor), Chreifi, G. (Contributor), Poulos, T. L. (Contributor), Silverman, R. B. (Contributor) (Mar 13 2019). Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine. Protein Data Bank (PDB). 10.2210/pdb6NHC/pdb

Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine

DOI

Access Dataset

Research output

Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold

Cite this