Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(4-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

Xue Fengtian Xue (Contributor)
Huiying Li (Contributor)
Silvia L. Delker (Contributor)
Jianguo Fang (Contributor)
Pavel Martásek (Contributor)
Linda J. Roman (Contributor)
Thomas L. Poulos (Contributor)
Richard B Silverman (Contributor)

Dataset

Date made available	Jan 19 2011
Publisher	Protein Data Bank (PDB)

DOI
10.2210/pdb3NLY/pdb

Access Dataset

https://www.wwpdb.org/pdb?id=pdb_00003nly

1 Article

Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase
Xue, F., Li, H., Delker, S. L., Fang, J., Martásek, P., Roman, L. J., Poulos, T. L. & Silverman, R. B., Oct 13 2010, In: Journal of the American Chemical Society. 132, 40, p. 14229-14238 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
62 Scopus citations

Cite this

Xue, F. (Contributor), Li, H. (Contributor), Delker, S. L. (Contributor), Fang, J. (Contributor), Martásek, P. (Contributor), Roman, L. J. (Contributor), Poulos, T. L. (Contributor), Silverman, R. B. (Contributor) (Jan 19 2011). Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(4-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine. Protein Data Bank (PDB). 10.2210/pdb3NLY/pdb

Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(4-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

DOI

Access Dataset

Research output

Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase

Cite this