Description
Accession Number: GSE66557
Platform:
GPL13112: Illumina HiSeq 2000 (Mus musculus)
Organism: Mus musculus
Published on 2015-09-01
Summary:
We profiled the skeletal muscle transcriptome between wild type and αB-crystallin/HspB2 knock mice exposed to normal chow and high fat diets to examine the role of αB-crystallin/HspB2 in diet induced obesity. Combined with metabolic profiling of the mice, these data reveal that αB-crystallin/HspB2 is involved in the genesis of insulin resistance on a high fat diet, and we provide extensive RNA profiling to illuminate potential mechanistic insights into the muscle-specific role of αB-crystallin/HspB2.
Overall Design:
Hind limb muscle mRNA profiles of wild type and αB-crystallin/HspB2 knock mice exposed to either normal chow or high fat diets using RNAseq analysis
Contact:
Name: Daniel Toft
Organization: Northwestern University
Deparment: Endocrinology
Address: 675 N. St. Clair Street, 14-100 Chicago IL 60611 USA
Email: [email protected]
Organization: GEO
Address: USA
Platform:
GPL13112: Illumina HiSeq 2000 (Mus musculus)
Organism: Mus musculus
Published on 2015-09-01
Summary:
We profiled the skeletal muscle transcriptome between wild type and αB-crystallin/HspB2 knock mice exposed to normal chow and high fat diets to examine the role of αB-crystallin/HspB2 in diet induced obesity. Combined with metabolic profiling of the mice, these data reveal that αB-crystallin/HspB2 is involved in the genesis of insulin resistance on a high fat diet, and we provide extensive RNA profiling to illuminate potential mechanistic insights into the muscle-specific role of αB-crystallin/HspB2.
Overall Design:
Hind limb muscle mRNA profiles of wild type and αB-crystallin/HspB2 knock mice exposed to either normal chow or high fat diets using RNAseq analysis
Contact:
Name: Daniel Toft
Organization: Northwestern University
Deparment: Endocrinology
Address: 675 N. St. Clair Street, 14-100 Chicago IL 60611 USA
Email: [email protected]
Organization: GEO
Address: USA
Date made available | Mar 5 2015 |
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Publisher | Gene Expression Omnibus |