Advanced Bioinformatics and Bio-Computation (ABBC) Core

Equipment/facility: Facility


The Advanced Bioinformatics and Bio-Computation (ABBC) Core, formerly the Bioinformatics Research Collaboratory (BIRC), provides consultative and collaborative services, analysis, support and design for high-throughput “omics” projects, such as next generation sequencing, microarrays, proteomics, etc. and clinical trial informatics. ABBC also offers custom web-based database development for basic science and clinical projects. The goal is to provide in-house bioinformatics expertise and support for the Northwestern University clinical and translational research community, especially for Feinberg researchers, in order to produce studies that ultimately result in publications and grants.


Computational Biology
Medical Informatics
Translational Medical Research
Biomedical Research
Clinical Trials


  • Consultation
  • GeneAnswers
  • MetaCore
  • GSEA
  • Analysis and data management
  • Exome-seq
  • Target-Seq
  • RNA-Seq
  • Chip-seq
  • DNA and RNA microarray data
  • Gene expression
  • Methylation
  • Exon and genotyping arrays
  • Proteomic data
  • Copy number variation
  • Variant calling
  • Biomarker identification
  • Cytotoxicity
  • Transcriptome mapping
  • Gene list interpretation
  • Meta-analysis of high-dimensional data
  • Pathway analysis
  • Hub gene analysis
  • GData mining
  • Data integration
  • Gene Ontology
  • KEGG Pathway
  • Reactome Pathway
  • NCI-Nature curated pathways
  • Disease Ontology
  • Bioconductor
  • GEO data submission
  • Grant assistance
  • Manuscript preparation assistance