Advanced Bioinformatics and Bio-Computation (ABBC) Core

Equipment/facility: Facility

Description

The Advanced Bioinformatics and Bio-Computation (ABBC) Core, formerly the Bioinformatics Research Collaboratory (BIRC), provides consultative and collaborative services, analysis, support and design for high-throughput “omics” projects, such as next generation sequencing, microarrays, proteomics, etc. and clinical trial informatics. ABBC also offers custom web-based database development for basic science and clinical projects. The goal is to provide in-house bioinformatics expertise and support for the Northwestern University clinical and translational research community, especially for Feinberg researchers, in order to produce studies that ultimately result in publications and grants.

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Bioinformatics
Microarrays
Throughput
Proteomics

Resources

  • Consultation
  • GeneAnswers
  • MetaCore
  • DAVID
  • WGCNA
  • GSEA
  • Analysis and data management
  • Exome-seq
  • Target-Seq
  • RNA-Seq
  • Chip-seq
  • DNA and RNA microarray data
  • Gene expression
  • Methylation
  • Exon and genotyping arrays
  • Proteomic data
  • Copy number variation
  • Variant calling
  • Biomarker identification
  • Cytotoxicity
  • Transcriptome mapping
  • Gene list interpretation
  • Meta-analysis of high-dimensional data
  • Pathway analysis
  • Hub gene analysis
  • GData mining
  • Data integration
  • Gene Ontology
  • KEGG Pathway
  • Reactome Pathway
  • NCI-Nature curated pathways
  • Disease Ontology
  • Bioconductor
  • GEO data submission
  • Grant assistance
  • Manuscript preparation assistance