BioCryo (Biological and Cryogenic Electron Microscopy) Facility

    Equipment/facility: Facility

      Description

      The integrated BioCryo Facility provides a comprehensive source for characterization of biological, soft matter and hybrid samples with TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy), and STEM (Scanning Transmission Electron Microscopy) at cryogenic or at ambient temperature. This facility provides expertise and equipment for cryofixation and processing of frozen hydrated samples by high-pressure freezing, plunge freezing, cryo fracturing, cryo ultramicrotomy, freeze substitution, and turbo freeze-drying. Conventional samples can be processed at ambient temperature with chemical fixation, dehydration, and resin embedding, or critical point drying.

      Fingerprint

      cryogenics
      electron microscopy
      freezing
      ambient temperature
      freeze drying
      transmission electron microscopy
      scanning electron microscopy
      fracturing
      dehydration
      embedding
      resins
      drying
      critical point
      substitutes

      Resources

      • Cryo SEM, and freeze-fracturing/etching
      • SE-, TE-, and Z-contrast imaging
      • Electron diffraction
      • Energy Dispersive X-ray Spectroscopy (EDS)
      • Electron Energy Loss Spectroscopy (EELS)