Sleep, Circadian and Other Rhythm Experiments Core

Equipment/facility: Facility

Description

The Sleep, Circadian and Other Rhythm Experiments (SCORE) Core's fundamental mission is to advance our understanding of rhythms in health and disease. The Core will be dedicated to supporting research of sleep, circadian, gene expression, endocrine, behavioral, and reproductive rhythms in rodent models. Equipment, experimental housing, and experienced personnel are available to carry out a wide range of experimental designs. The Core will also offer training and consulting in experimental design and data analysis of rhythm studies.

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Circadian Rhythm
Sleep
Research Design
Rodentia
Gene Expression
Equipment and Supplies
Health

Resources

  • Statistical analysis of cyclic data using circular distribution or curve-fitting algorithms
  • Recording and analysis of rodent sleep by Electroencephalogram (EEG) and Electromyogram (EMG)
  • Quantification of rhythm parameters such as amplitude
  • phase
  • or period
  • for a variety of data types
  • Single-sex housing environments
  • Monitoring of estrous cycle
  • Cycle-timed behavioral tests
  • experimental manipulations
  • or food availability
  • Time-specific administration of test compounds or sample collection including in darkness with infrared viewer
  • Recording of feeding or drinking behavior rhythms
  • Recording of body temperature rhythms
  • Recording locomotor activity rhythms by wheel-running
  • InfraRed beam break
  • or telemetry
  • Non-standard temporal environments for housing study animals