Biochemistry and Molecular Genetics

Search results

  • 2015

    MicroRNA-mediated transformation by the Kaposi's sarcomaassociated herpesvirus Kaposin locus

    Forte, E., Raja, A. N., Shamulailatpam, P., Manzano, M., Schipma, M. J., Casey, J. L. & Gottwein, E., 2015, In: Journal of virology. 89, 4, p. 2333-2341 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II via Transcriptional Elongation Control in Mitosis

    Liang, K., Woodfin, A. R., Slaughter, B. D., Unruh, J. R., Box, A. C., Rickels, R. A., Gao, X., Haug, J. S., Jaspersen, S. L. & Shilatifard, A., Nov 5 2015, In: Molecular cell. 60, 3, p. 435-445 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    86 Scopus citations

  • Myocardin-related transcription factors are required for cardiac development and function

    Mokalled, M. H., Carroll, K. J., Cenik, B. K., Chen, B., Liu, N., Olson, E. N. & Bassel-Duby, R., Oct 15 2015, In: Developmental Biology. 406, 2, p. 109-116 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • NF-ΚB and IRF pathways: Cross-regulation on target genes promoter level

    Iwanaszko, M. & Kimmel, M., Apr 17 2015, In: BMC Genomics. 16, 1, 307.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    106 Scopus citations

  • O-GlcNAcylation of co-activator-associated arginine methyltransferase 1 regulates its protein substrate specificity

    Charoensuksai, P., Kuhn, P., Wang, L., Sherer, N. & Xu, W., Mar 15 2015, In: Biochemical Journal. 466, 3, p. 587-599 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Oral administration of Lactobacillus plantarum 299v modulates gene expression in the ileum of pigs: prediction of crosstalk between intestinal immune cells and sub-mucosal adipocytes

    Hulst, M., Gross, G., Liu, Y., Hoekman, A., Niewold, T., van der Meulen, J. & Smits, M., May 1 2015, In: Genes and Nutrition. 10, 3, p. 1-13 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Origin and domestication of papaya Yh chromosome

    VanBuren, R., Zeng, F., Chen, C., Zhang, J., Wai, C. M., Han, J., Aryal, R., Gschwend, A. R., Wang, J., Na, J. K., Huang, L., Zhang, L., Miao, W., Gou, J., Arro, J., Guyot, R., Moore, R. C., Wang, M. L., Zee, F. & Charlesworth, D. & 3 others, Moore, P. H., Yu, Q. & Ming, R., Apr 1 2015, In: Genome research. 25, 4, p. 524-533 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    80 Scopus citations

  • PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II

    Chen, F. X., Woodfin, A. R., Gardini, A., Rickels, R. A., Marshall, S. A., Smith, E. R., Shiekhattar, R. & Shilatifard, A., Aug 27 2015, In: Cell. 162, 5, p. 1003-1015 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    177 Scopus citations

  • Pancreatic b cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

    Perelis, M., Marcheva, B., Ramsey, K. M., Schipma, M. J., Hutchison, A. L., Taguchi, A., Peek, C. B., Hong, H., Huang, W., Omura, C., Allred, A. L., Bradfield, C. A., Dinner, A. R., Barish, G. D. & Bass, J., Nov 6 2015, In: Science. 350, 6261

    Research output: Contribution to journal › Article › peer-review

    Open Access
    309 Scopus citations

  • Part 4: Targeting cancer pathways: The epigenetics question

    Baylin, S. B., Roberts, C. & Shilatifard, A., Aug 7 2015, In: Science. 349, 6248, 656.

    Research output: Contribution to journal › Article › peer-review

  • Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development

    Yang, H., Fang, L., Zhan, R., Hegarty, J. M., Ren, J., Hsiai, T. K., Gleeson, J. G., Miller, Y. I., Trejo, J. A. & Chi, N. C., Aug 15 2015, In: Developmental Biology. 404, 2, p. 49-60 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations

  • Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function

    Hu, Y., Wang, L., Wang, L., Wu, X., Wu, X., Gu, Y., Shu, Y., Sun, Y., Shen, Y. & Xu, Q., Feb 5 2015, In: Toxicology and Applied Pharmacology. 283, 1, p. 1-8 8 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Programmable probiotics for detection of cancer in urine

    Danino, T., Prindle, A., Kwong, G. A., Skalak, M., Li, H., Allen, K., Hasty, J. & Bhatia, S. N., May 27 2015, In: Science translational medicine. 7, 289, 289ra84.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    345 Scopus citations

  • Reciprocal Regulation of ERα and ERβ Stability and Activity by Diptoindonesin G

    Zhao, Z., Wang, L., James, T., Jung, Y., Kim, I., Tan, R., Hoffmann, F. M. & Xu, W., Dec 17 2015, In: Chemistry and Biology. 22, 12, p. 1608-1621 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations

  • Restrictive disease of the respiratory system

    Singer, B., Corbridge, T. & Wood, L., 2015, Principles of Critical Care, 4th Edition. Hall, J., Schmidt, G. & Kress, J. (eds.). New York, NY: McGraw-Hill

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer

    Cao, C., Gao, R., Zhang, M., Amelio, A. L., Fallahi, M., Chen, Z., Gu, Y., Hu, C., Welsh, E. A., Engel, B. E., Haura, E. B., Cress, W. D., Wu, L., Zajac-Kaye, M. & Kaye, F. J., Jan 1 2015, In: Journal of the National Cancer Institute. 107, 1, dju358.

    Research output: Contribution to journal › Article › peer-review

    40 Scopus citations

  • Sequence-tagged high-density genetic maps of Zoysia japonica provide insights into genome evolution in Chloridoideae

    Wang, F., Singh, R., Genovesi, A. D., Wai, C. M., Huang, X., Chandra, A. & Yu, Q., Jun 1 2015, In: Plant Journal. 82, 5, p. 744-757 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • Severe myopathy in mice lacking the MEF2/SRFdependent gene leiomodin-3

    Cenik, B. K., Garg, A., McAnally, J. R., Shelton, J. M., Richardson, J. A., Bassel-Duby, R., Olson, E. N. & Liu, N., Apr 1 2015, In: Journal of Clinical Investigation. 125, 4, p. 1569-1578 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus

    Halavaty, A. S., Rich, R. L., Chen, C., Joo, J. C., Minasov, G., Dubrovska, I., Winsor, J. R., Myszka, D. G., Duban, M., Shuvalova, L., Yakunin, A. F. & Anderson, W. F., May 1 2015, In: Acta Crystallographica Section D: Biological Crystallography. 71, p. 1159-1175 17 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Structure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy

    Chen, P. H., Unger, V. & He, X., Dec 4 2015, In: Journal of Molecular Biology. 427, 24, p. 3921-3934 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations

  • Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG

    Filippova, E. V., Weigand, S., Osipiuk, J., Kiryukhina, O., Joachimiak, A. & Anderson, W. F., Jun 17 2015, In: Journal of Molecular Biology. 427, 22, p. 3538-3553 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Supramolecular assembly of multifunctional maspin-mimetic nanostructures as a potent peptide-based angiogenesis inhibitor

    Zha, R. H., Sur, S., Boekhoven, J., Shi, H. Y., Zhang, M. & Stupp, S. I., 2015, In: Acta Biomaterialia. 12, C, p. 1-10 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • Targeting Human Central Nervous System Protein Kinases: An Isoform Selective p38αMAPK Inhibitor That Attenuates Disease Progression in Alzheimer's Disease Mouse Models

    Roy, S. M., Grum-Tokars, V. L., Schavocky, J. P., Saeed, F., Staniszewski, A., Teich, A. F., Arancio, O., Bachstetter, A. D., Webster, S. J., Van Eldik, L. J., Minasov, G., Anderson, W. F., Pelletier, J. C. & Watterson, D. M., Apr 15 2015, In: ACS Chemical Neuroscience. 6, 4, p. 666-680 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    78 Scopus citations

  • The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output

    Stijf-Bultsma, Y., Sommer, L., Tauber, M., Baalbaki, M., Giardoglou, P., Jones, D. R., Gelato, K. A., vanPelt, J., Shah, Z., Rahnamoun, H., Toma, C., Anderson, K. E., Hawkins, P., Lauberth, S. M., Haramis, A. P. G., Hart, D., Fischle, W. & Divecha, N., May 7 2015, In: Molecular cell. 58, 3, p. 453-467 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    56 Scopus citations

  • The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites

    Abouelfetouh, A., Kuhn, M. L., Hu, L. I., Scholle, M. D., Sorensen, D. J., Sahu, A. K., Becher, D., Antelmann, H., Mrksich, M., Anderson, W. F., Gibson, B. W., Schilling, B. & Wolfe, A. J., Feb 1 2015, In: MicrobiologyOpen. 4, 1, p. 66-83 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    88 Scopus citations

  • The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development

    Ortega-Molina, A., Boss, I. W., Canela, A., Pan, H., Jiang, Y., Zhao, C., Jiang, M., Hu, D., Agirre, X., Niesvizky, I., Lee, J. E., Chen, H. T., Ennishi, D., Scott, D. W., Mottok, A., Hother, C., Liu, S., Cao, X. J., Tam, W. & Shaknovich, R. & 8 others, Garcia, B. A., Gascoyne, R. D., Ge, K., Shilatifard, A., Elemento, O., Nussenzweig, A., Melnick, A. M. & Wendel, H. G., Oct 1 2015, In: Nature Medicine. 21, 10, p. 1199-1208 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    352 Scopus citations

  • The pineapple genome and the evolution of CAM photosynthesis

    Ming, R., VanBuren, R., Wai, C. M., Tang, H., Schatz, M. C., Bowers, J. E., Lyons, E., Wang, M. L., Chen, J., Biggers, E., Zhang, J., Huang, L., Zhang, L., Miao, W., Zhang, J., Ye, Z., Miao, C., Lin, Z., Wang, H. & Zhou, H. & 50 others, Yim, W. C., Priest, H. D., Zheng, C., Woodhouse, M., Edger, P. P., Guyot, R., Guo, H. B., Guo, H., Zheng, G., Singh, R., Sharma, A., Min, X., Zheng, Y., Lee, H., Gurtowski, J., Sedlazeck, F. J., Harkess, A., McKain, M. R., Liao, Z., Fang, J., Liu, J., Zhang, X., Zhang, Q., Hu, W., Qin, Y., Wang, K., Chen, L. Y., Shirley, N., Lin, Y. R., Liu, L. Y., Hernandez, A. G., Wright, C. L., Bulone, V., Tuskan, G. A., Heath, K., Zee, F., Moore, P. H., Sunkar, R., Leebens-Mack, J. H., Mockler, T., Bennetzen, J. L., Freeling, M., Sankoff, D., Paterson, A. H., Zhu, X., Yang, X., Smith, J. A. C., Cushman, J. C., Paull, R. E. & Yu, Q., Dec 1 2015, In: Nature Genetics. 47, 12, p. 1435-1442 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    424 Scopus citations

  • The role of DNA methylation in directing the functional organization of the cancer epigenome

    Lay, F. D., Liu, Y., Kelly, T. K., Witt, H., Farnham, P. J., Jones, P. A. & Berman, B. P., Apr 1 2015, In: Genome research. 25, 4, p. 467-477 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    80 Scopus citations

  • The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions

    Ruan, J., Mouveaux, T., Light, S. H., Minasov, G., Anderson, W. F., Tomavo, S. & Ngô, H. M., Mar 1 2015, In: Acta Crystallographica Section D: Biological Crystallography. 71, p. 417-426 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • The Yeast Prion [SWI+] Abolishes Multicellular Growth by Triggering Conformational Changes of Multiple Regulators Required for Flocculin Gene Expression

    Du, Z., Zhang, Y. & Li, L., Dec 29 2015, In: Cell reports. 13, 12, p. 2865-2878 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Translatome analyses capture of opposing tissuespecific brassinosteroid signals orchestrating root meristem differentiation

    Vragović, K., Selaa, A., Friedlander-Shani, L., Fridman, Y., Hacham, Y., Holland, N., Bartom, E., Mockler, T. C. & Savaldi-Goldstein, S., Jan 20 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 3, p. 923-928 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    99 Scopus citations

  • Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations

    Stockman, D. L., Curry, J. L., Torres-Cabala, C. A., Watson, I. R., Siroy, A. E., Bassett, R. L., Zou, L., Patel, K. P., Luthra, R., Davies, M. A., Wargo, J. A., Routbort, M. A., Broaddus, R. R., Prieto, V. G., Lazar, A. J. & Tetzlaff, M. T., May 1 2015, In: Journal of cutaneous pathology. 42, 5, p. 308-317 10 p.

    Research output: Contribution to journal › Article › peer-review

    11 Scopus citations

  • Virtual High-Throughput Screening to Identify Novel Activin Antagonists

    Zhu, J., Mishra, R. K., Schiltz, G. E., Makanji, Y., Scheidt, K. A., Mazar, A. P. & Woodruff, T. K., Jul 23 2015, In: Journal of Medicinal Chemistry. 58, 14, p. 5637-5648 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Zic2 is an enhancer-binding factor required for embryonic stem cell specification

    Luo, Z., Gao, X., Lin, C., Smith, E. R., Marshall, S. A., Swanson, S. K., Florens, L., Washburn, M. P. & Shilatifard, A., Feb 19 2015, In: Molecular cell. 57, 4, p. 685-694 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    78 Scopus citations
  • 2014

    Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells

    Chen, Z., Chen, J., Gu, Y., Hu, C., Li, J. L., Lin, S., Shen, H., Cao, C., Gao, R., Li, J., Ha, P. K., Kaye, F. J., Griffin, J. D. & Wu, L., Jul 17 2014, In: Oncogene. 33, 29, p. 3869-3877 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    79 Scopus citations

  • Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS

    Keerthivasan, G., Mei, Y., Zhao, B., Zhang, L., Harris, C. E., Gao, J., Basiorka, A. A., Schipma, M. J., McElherne, J., Yang, J., Verma, A. K., Pellagatti, A., Boultwood, J., List, A. F., Williams, D. A. & Ji, P., Jul 31 2014, In: Blood. 124, 5, p. 780-790 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • A comparative encyclopedia of DNA elements in the mouse genome

    Yue, F., Cheng, Y., Breschi, A., Vierstra, J., Wu, W., Ryba, T., Sandstrom, R., Ma, Z., Davis, C., Pope, B. D., Shen, Y., Pervouchine, D. D., Djebali, S., Thurman, R. E., Kaul, R., Rynes, E., Kirilusha, A., Marinov, G. K., Williams, B. A. & Trout, D. & 117 others, Amrhein, H., Fisher-Aylor, K., Antoshechkin, I., DeSalvo, G., See, L. H., Fastuca, M., Drenkow, J., Zaleski, C., Dobin, A., Prieto, P., Lagarde, J., Bussotti, G., Tanzer, A., Denas, O., Li, K., Bender, M. A., Zhang, M., Byron, R., Groudine, M. T., McCleary, D., Pham, L., Ye, Z., Kuan, S., Edsall, L., Wu, Y. C., Rasmussen, M. D., Bansal, M. S., Kellis, M., Keller, C. A., Morrissey, C. S., Mishra, T., Jain, D., Dogan, N., Harris, R. S., Cayting, P., Kawli, T., Boyle, A. P., Euskirchen, G., Kundaje, A., Lin, S., Lin, Y., Jansen, C., Malladi, V. S., Cline, M. S., Erickson, D. T., Kirkup, V. M., Learned, K., Sloan, C. A., Rosenbloom, K. R., De Sousa, B. L., Beal, K., Pignatelli, M., Flicek, P., Lian, J., Kahveci, T., Lee, D., Kent, W. J., Santos, M. R., Herrero, J., Notredame, C., Johnson, A., Vong, S., Lee, K., Bates, D., Neri, F., Diegel, M., Canfield, T., Sabo, P. J., Wilken, M. S., Reh, T. A., Giste, E., Shafer, A., Kutyavin, T., Haugen, E., Dunn, D., Reynolds, A. P., Neph, S., Humbert, R., Hansen, R. S., De Bruijn, M., Selleri, L., Rudensky, A., Josefowicz, S., Samstein, R., Eichler, E. E., Orkin, S. H., Levasseur, D., Papayannopoulou, T., Chang, K. H., Skoultchi, A., Gosh, S., Disteche, C., Treuting, P., Wang, Y., Weiss, M. J., Blobel, G. A., Cao, X., Zhong, S., Wang, T., Good, P. J., Lowdon, R. F., Adams, L. B., Zhou, X. Q., Pazin, M. J., Feingold, E. A., Wold, B., Taylor, J., Mortazavi, A., Weissman, S. M., Stamatoyannopoulos, J. A., Snyder, M. P., Guigo, R., Gingeras, T. R., Gilbert, D. M., Hardison, R. C., Beer, M. A. & Ren, B., Nov 20 2014, In: Nature. 515, 7527, p. 355-364 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1270 Scopus citations

  • Adherence to Bürgi-Dunitz stereochemical principles requires significant structural rearrangements in Schiff-base formation: Insights from transaldolase complexes

    Light, S. H., Minasov, G., Duban, M. E. & Anderson, W. F., Feb 2014, In: Acta Crystallographica Section D: Biological Crystallography. 70, 2, p. 544-552 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations

  • An insight into the complex prion-prion interaction network in the budding yeast Saccharomyces cerevisiae

    Du, Z., Valtierra, S. & Li, L., Nov 1 2014, In: Prion. 8, 6, p. 387-392 6 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    6 Scopus citations

  • A potential regulatory loop between Lin28B:miR-212 in androgen-independent prostate cancer

    Borrego-Diaz, E., Powers, B. C., Azizov, V., Lovell, S., Reyes, R., Chapman, B., Tawfik, O., McGregor, D., Diaz, F. J., Wang, X. & Van Veldhuizen, P., 2014, In: International journal of oncology. 45, 6, p. 2421-2429 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Arabinose 5-phosphate covalently inhibits transaldolase

    Light, S. H. & Anderson, W. F., Mar 2014, In: Journal of Structural and Functional Genomics. 15, 1, p. 41-44 4 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers

    Cheng, J., Blum, R., Bowman, C., Hu, D., Shilatifard, A., Shen, S. & Dynlacht, B. D., Mar 20 2014, In: Molecular cell. 53, 6, p. 979-992 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    167 Scopus citations

  • A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

    Gao, R., Cao, C., Zhang, M., Lopez, M. C., Yan, Y., Chen, Z., Mitani, Y., Zhang, L., Zajac-Kaye, M., Liu, B., Wu, L., Renne, R., Baker, H. V., El-Naggar, A. & Kaye, F. J., 2014, In: Oncotarget. 5, 24, p. 12528-12542 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis

    Wang, L., Zhao, Z., Meyer, M. B., Saha, S., Yu, M., Guo, A., Wisinski, K. B., Huang, W., Cai, W., Pike, J. W., Yuan, M., Ahlquist, P. & Xu, W., Jan 13 2014, In: Cancer cell. 25, 1, p. 21-36 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    198 Scopus citations

  • Centromere licensing: Mis18 is required to Polo-ver

    Barnhart-Dailey, M. C. & Foltz, D. R., Sep 8 2014, In: Current Biology. 24, 17, p. R808-R810

    Research output: Contribution to journal › Short survey › peer-review

    Open Access
    3 Scopus citations

  • Chromosome length and perinuclear attachment constrain resolution of DNA intertwines

    Titos, I., Ivanova, T. & Mendoza, M., 2014, In: Journal of Cell Biology. 206, 6, p. 719-733 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • Comprehensive molecular characterization of gastric adenocarcinoma

    Bass, A. J., Thorsson, V., Shmulevich, I., Reynolds, S. M., Miller, M., Bernard, B., Hinoue, T., Laird, P. W., Curtis, C., Shen, H., Weisenberger, D. J., Schultz, N., Shen, R., Weinhold, N., Kelsen, D. P., Bowlby, R., Chu, A., Kasaian, K., Mungall, A. J. & Robertson, A. G. & 31 others, Sipahimalani, P., Cherniack, A. D., Getz, G., Liu, Y., Noble, M. S., Pedamallu, C., Sougnez, C., Taylor-Weiner, A., Akbani, R., Lee, J. S., Liu, W., Mills, G. B., Yang, D., Zhang, W., Pantazi, A., Parfenov, M., Gulley, M., Piazuelo, M. B., Schneider, B. G., Kim, J., Boussioutas, A., Sheth, M., Demchok, J. A., Rabkin, C. S., Willis, J. E., Ng, S., Garman, K., Beer, D. G., Pennathur, A., Zou, L. & Cancer Genome Atlas Research Network, Sep 11 2014, In: Nature. 513, 7517, p. 202-209 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5016 Scopus citations

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    Weinstein, J. N., Akbani, R., Broom, B. M., Wang, W., Verhaak, R. G. W., McConkey, D., Lerner, S., Morgan, M., Creighton, C. J., Smith, C., Cherniack, A. D., Kim, J., Pedamallu, C. S., Noble, M. S., Al-Ahmadie, H. A., Reuter, V. E., Rosenberg, J. E., F.Bajorin, D., Bochner, B. H. & Solit, D. B. & 273 others, Koppie, T., Robinson, B., Gordenin, D. A., Fargo, D., Klimczak, L. J., Roberts, S. A., Au, J., Laird, P. W., Hinoue, T., Schultz, N., Ramirez, R., Hansel, D., Hoadley, K. A., Kim, W. Y., Damrauer, J. S., Baylin, S. B., Mungall, A. J., Robertson, A. G., Chu, A., Kwiatkowski, D. J., Sougnez, C., Cibulskis, K., Lichtenstein, L., Sivachenko, A., Stewart, C., Lawrence, M. S., Getz, G., Lander, E., Gabrie, S. B., Donehower, L., Carter, S. L., Saksena, G., Schumacher, S. E., Freeman, S. S., Jung, J., Bhatt, A. S., Pugh, T., Beroukhim, R., Meyerson, M., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Dhalla, N., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Wong, T., Wye, N., Bowlby, R., Chuah, E., Guin, R., Shen, H., Bootwalla, M. S., Triche, T., Lai, P. H., Van Den Berg, D. J., Weisenberger, D. J., Balu, S., Bodenheimer, T., Hoyle, A. P., Jefferys, S. R., Meng, S., Mose, L. E., Simons, J. V., Soloway, M. G., Wu, J., Parker, J. S., Hayes, D. N., Roach, J., Buda, E., Jones, C. D., Mieczkowski, P. A., Tan, D., Veluvolu, U., Waring, S., Auman, J. T., Perou, C. M., Wilkerson, M. D., Santoso, N., Parfenov, M., Ren, X., Pantazi, A., Hadjipanayis, A., Seidman, J., Kucherlapati, R., Lee, S., Yang, L., Park, P. J., Xu, A. W., Protopopov, A., Zhang, J., Bristow, C., Mahadeshwar, H. S., Seth, S., Song, X., Tang, J., Zeng, D., Chin, L., Guo, C., Casasent, T. D., Liu, W., Ju, Z., Motter, T., Peng, B., Ryan, M., Su, X., Yang, J. Y., Lorenzi, P. L., Yao, H., Zhang, N., Zhang, J., Mills, G. B., Cho, J., DiCara, D., Frazer, S., Gehlenborg, N., Heiman, D. I., Lin, P., Liu, Y., Stojanov, P., Voet, D., Zhang, H., Zou, L., Bernard, B., Kreisberg, D., Reynolds, S., Rovira, H., Shmulevich, I., Gao, J., Jacobsen, A., Aksoy, B. A., Antipin, Y., Ciriello, G., Dresdner, G., Gross, B., Lee, W., Reva, B., Shen, R., Sinha, R., Sumer, S. O., Weinhold, N., Ladanyi, M., Sander, C., Benz, C., Carlin, D., Haussler, D., Ng, S., Paull, E., Stuart, J., Zhu, J., Liu, Y., Zhang, W., Taylor, B. S., Lichtenberg, T. M., Zmuda, E., Barr, T., Black, A. D., George, M., Hanf, B., Helsel, C., McAllister, C., Ramirez, N. C., Tabler, T. R., Weaver, S., Wise, L., Bowen, J., Gastier-Foster, J. M., Jian, W., Tello, S., Ittman, M., Castro, P., McClenden, W. D., Gibbs, R., Saller, C., Tarvin, K., DiPiero, J. M., Owens, J., Bollag, R., Li, Q., Weinberger, P., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Swanson, P., Shelton, T., Curley, E., Gardner, J., Mallery, D., Penny, R., Van Bang, N., Hanh, P. T., Kohl, B., Van Le, X., Phu, B. D., Thorp, R., Tien, N. V., Vinh, L. Q., Sandusky, G., Burks, E., Christ, K., Gee, J., Holway, A., Moinzadeh, A., Sorcini, A., Sullivan, T., Garcia-Grossman, I. R., Regazzi, A. M., Boice, L., Rathmell, W. K., Thorne, L., Bastacky, S., Davies, B., Dhir, R., Gingrich, J., Hrebinko, R., Maranchie, J., Nelson, J., Parwani, A., Bshara, W., Gaudioso, C., Morrison, C., Alexopoulou, V., Bartlett, J., Engel, J., Kodeeswaran, S., Antic, T., O'Donnell, P. H., Smith, N. D., Steinberg, G. D., Egea, S., Gomez-Fernandez, C., Herbert, L., Jorda, M., Soloway, M., Beaver, A., Carter, S., Kapur, P., Lewis, C., Lotan, Y., Bondaruk, J., Czerniak, B., Skinner, E., Aldape, K., Jensen, M. A., Kahn, A. B., Pihl, T. D., Pot, D. A., Srinivasan, D., Wan, Y., Ferguson, M. L., Zenklusen, J. C., Davidsen, T., Demchok, J. A., Shaw, K. R. M., Sheth, M., Tarnuzzer, R., Wang, Z., Yang, L., Hutter, C., Ozenberger, B. A., Sofia, H. J. & Eley, G., 2014, In: Nature. 507, 7492, p. 315-322 8 p.

    Research output: Contribution to journal › Article › peer-review

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    2455 Scopus citations

  • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Collisson, E. A., Campbell, J. D., Brooks, A. N., Berger, A. H., Lee, W., Chmielecki, J., Beer, D. G., Cope, L., Creighton, C. J., Danilova, L., Ding, L., Getz, G., Hammerman, P. S., Hayes, D. N., Hernandez, B., Herman, J. G., Heymach, J. V., Jurisica, I., Kucherlapati, R. & Kwiatkowski, D. & 290 others, Ladanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M. S., Travis, W. D., Weinstein, J. N., Wigle, D. A., Wilkerson, M. D., Chu, A., Cherniack, A. D., Hadjipanayis, A., Rosenberg, M., Weisenberger, D. J., Laird, P. W., Radenbaugh, A., Ma, S., Stuart, J. M., Byers, L. A., Baylin, S. B., Govindan, R., Meyerson, M., Gabriel, S. B., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E. S., Lawrence, M. S., Getz, E., Fulton, R., Fulton, L. L., McLellan, M. D., Wilson, R. K., Ye, K., Fronick, C. C., Maher, C. A., Miller, C. A., Wendl, M. C., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R., Robertson, A. G., Wye, N., Thiessen, N., Holt, R. A., Jones, S. J. M., Marra, M. A., Imielinski, M., Onofrio, R. C., Hodis, E., Zack, T., Helman, E., Pedamallu, C. S., Mesirov, J., Saksena, G., Schumacher, S. E., Carter, S. L., Garraway, L., Beroukhim, R., Lee, S., Mahadeshwar, H. S., Pantazi, A., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Yang, L., Zhang, J., Chen, P. C., Parfenov, M., Xu, A. W., Santoso, N., Chin, L., Park, P. J., Hoadley, K. A., Auman, J. T., Meng, S., Shi, Y., Buda, E., Waring, S., Veluvolu, U., Tan, D., Mieczkowski, P. A., Jones, C. D., Simons, J. V., Soloway, M. G., Bodenheimer, T., Jefferys, S. R., Roach, J., Hoyle, A. P., Wu, J., Balu, S., Singh, D., Prins, J. F., Marron, J. S., Parker, J. S., Perou, C. M., Liu, J., Maglinte, D. T., Lai, P. H., Bootwalla, M. S., Van Den Berg, D. J., Triche, T., Cho, J., DiCara, D., Heiman, D., Lin, P., Mallard, W., Voet, D., Zhang, H., Zou, L., Noble, M. S., Gehlenborg, N., Thorvaldsdottir, H., Nazaire, M. D., Robinson, J., Aksoy, B. A., Ciriello, G., Taylor, B. S., Dresdner, G., Gao, J., Gross, B., Seshan, V. E., Reva, B., Sumer, S. O., Weinhold, N., Sander, C., Ng, S., Zhu, J., Benz, C. C., Yau, C., Haussler, D., Spellman, P. T., Kimes, P. K., Broom, B. M., Wang, J., Lu, Y., Ng, P. K. S., Diao, L., Liu, W., Amos, C. I., Akbani, R., Mills, G. B., Curley, E., Paulauskis, J., Lau, K., Morris, S., Shelton, T., Mallery, D., Gardner, J., Penny, R., Saller, C., Tarvin, K., Richards, W. G., Cerfolio, R., Bryant, A., Raymond, D. P., Pennell, N. A., Farver, C., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Brown, J., Bauer, T., Dolzhanskiy, C. O., Potapova, O., Rotin, D., Voronina, O., Nemirovich-Danchenko, E., Fedosenko, K. V., Gal, A., Behera, M., Ramalingam, S. S., Sica, G., Flieder, D., Boyd, J., Weaver, J. E., Kohl, B., Thinh, D. H. Q., Sandusky, G., Juhl, H., Duhig, E., Illei, P., Gabrielson, E., Shin, J., Lee, B., Rogers, K., Trusty, D., Brock, M. V., Williamson, C., Burks, E., Rieger-Christ, K., Holway, A., Sullivan, T., Asiedu, M. K., Kosari, F., Rekhtman, N., Zakowski, M., Rusch, V. W., Zippile, P., Suh, J., Pass, H., Goparaju, C., Owusu-Sarpong, Y., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Sekhon, H., Albert, M., Eckman, J., Myers, J. B., Morrison, C., Gaudioso, C., Borgia, J. A., Bonomi, P., Pool, M., Liptay, M. J., Moiseenko, F., Zaytseva, I., Dienemann, H., Meister, M., Schnabel, P. A., Muley, T. R., Peifer, M., Gomez-Fernandez, C., Herbert, L., Egea, S., Huang, M., Thorne, L. B., Boice, L., Salazar, A. H., Funkhouser, W. K., Rathmell, W. K., Dhir, R., Yousem, S. A., Dacic, S., Schneider, F., Siegfried, J. M., Hajek, R., Watson, M. A., McDonald, S., Meyers, B., Clarke, B., Yang, I. A., Fong, K. M., Hunter, L., Windsor, M., Bowman, R. V., Peters, S., Letovanec, I., Khan, K. Z., Jensen, M. A., Snyder, E. E., Srinivasan, D., Kahn, A. B., Baboud, J., Pot, D. A., Shaw, K. R. M., Sheth, M., Davidsen, T., Demchok, J. A., Yang, L., Wang, Z., Tarnuzzer, R., Zenklusen, J. C., Ozenberger, B. A., Sofia, H. J. & Cheney, R., 2014, In: Nature. 511, 7511, p. 543-550 8 p.

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    4328 Scopus citations

  • Context dependency of Set1/ COMPASS-mediated histone H3 Lys4 trimethylation

    Thornton, J. L., Westfield, G. H., Takahashi, Y. H., Cook, M., Gao, X., Woodfin, A. R., Lee, J. S., Morgan, M. A., Jackson, J., Smith, E. R., Couture, J. F., Skiniotis, G. & Shilatifard, A., Jan 15 2014, In: Genes and Development. 28, 2, p. 115-120 6 p.

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    43 Scopus citations