Biochemistry and Molecular Genetics

Search results

  • 2013

    The PR/SET domain Zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo

    Bogani, D., Morgan, M. A. J., Nelson, A. C., Costello, I., McGouran, J. F., Kessler, B. M., Robertson, E. J. & Bikoff, E. K., 2013, In: Molecular and cellular biology. 33, 19, p. 3936-3950 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage

    Chaumeil, J., Micsinai, M., Ntziachristos, P., Roth, D. B., Aifantis, I., Kluger, Y., Deriano, L. & Skok, J. A., 2013, In: Nature communications. 4, 2231.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation

    Lin, C., Garruss, A. S., Luo, Z., Guo, F. & Shilatifard, A., Jan 7 2013, In: Cell. 152, 1-2, p. 144-156 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    82 Scopus citations

  • The somatic genomic landscape of glioblastoma

    Brennan, C. W., Verhaak, R. G. W., McKenna, A., Campos, B., Noushmehr, H., Salama, S. R., Zheng, S., Chakravarty, D., Sanborn, J. Z., Berman, S. H., Beroukhim, R., Bernard, B., Wu, C. J., Genovese, G., Shmulevich, I., Barnholtz-Sloan, J., Zou, L., Vegesna, R., Shukla, S. A. & Ciriello, G. & 31 others, Yung, W. K., Zhang, W., Sougnez, C., Mikkelsen, T., Aldape, K., Bigner, D. D., Van Meir, E. G., Prados, M., Sloan, A., Black, K. L., Eschbacher, J., Finocchiaro, G., Friedman, W., Andrews, D. W., Guha, A., Iacocca, M., O'Neill, B. P., Foltz, G., Myers, J., Weisenberger, D. J., Penny, R., Kucherlapati, R., Perou, C. M., Hayes, D. N., Gibbs, R., Marra, M., Mills, G. B., Lander, E., Spellman, P., Brat, D. & TCGA Research Network, Oct 10 2013, In: Cell. 155, 2, p. 462 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3802 Scopus citations

  • The structural basis of R-spondin recognition by LGR5 and RNF43

    Chen, P. H., Chen, X., Lin, Z., Fang, D. & He, X., Jun 15 2013, In: Genes and Development. 27, 12, p. 1345-1350 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    118 Scopus citations

  • Theta Replication

    Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, p. 66 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • The TSC-mTOR pathway regulates macrophage polarization

    Byles, V., Covarrubias, A. J., Ben-Sahra, I., Lamming, D. W., Sabatini, D. M., Manning, B. D. & Horng, T., Nov 27 2013, In: Nature communications. 4, 2834.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    474 Scopus citations

  • Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

    Santagata, S., Mendillo, M. L., Tang, Y. C., Subramanian, A., Perley, C. C., Roche, S. P., Wong, B., Narayan, R., Kwon, H., Koeva, M., Amon, A., Golub, T. R., Porco, J. A., Whitesell, L. & Lindquist, S., 2013, In: Science. 341, 6143, 1238303.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    220 Scopus citations

  • Transcriptional elongation checkpoint control in development and disease

    Smith, E. & Shilatifard, A., May 15 2013, In: Genes and Development. 27, 10, p. 1079-1088 10 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    58 Scopus citations

  • Tumor STAT1 transcription factor activity enhances breast tumor growth and immune suppression mediated by myeloid-derived suppressor cells

    Hix, L. M., Karavitis, J., Khan, M. W., Shi, Y. H., Khazaie, K. & Zhang, M., Apr 26 2013, In: Journal of Biological Chemistry. 288, 17, p. 11676-11688 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    106 Scopus citations

  • Tumor-suppressive maspin functions as a reactive oxygen species scavenger: Importance of cysteine residues

    Mahajan, N., Shi, H. Y., Lukas, T. J. & Zhang, M., Apr 19 2013, In: Journal of Biological Chemistry. 288, 16, p. 11611-11620 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development

    Hegarty, J. M., Yang, H. & Chi, N. C., Apr 2013, In: Development (Cambridge). 140, 8, p. 1713-1719 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • Vps41, a protein involved in lysosomal trafficking, interacts with caspase-8

    Wang, L., Pan, X., He, L., Zhang, R., Chen, W., Zhang, J., Lu, M. & Hua, Z. C., 2013, In: Acta biochimica Polonica. 60, 1, p. 37-42 6 p.

    Research output: Contribution to journal › Article › peer-review

    3 Scopus citations

  • XA histone modifier's ill-gotten copy gains

    Rickels, R. & Shilatifard, A., Aug 1 2013, In: Cell. 154, 3, p. X477-479

    Research output: Contribution to journal › Short survey › peer-review

    Open Access
    2 Scopus citations

  • Xiao-Ai-Ping, a TCM injection, enhances the antigrowth effects of cisplatin on lewis lung cancer cells through promoting the infiltration and function of CD8+ T Lymphocytes

    Li, W., Yang, Y., Ouyang, Z., Zhang, Q., Wang, L., Tao, F., Shu, Y., Gu, Y., Xu, Q. & Sun, Y., 2013, In: Evidence-based Complementary and Alternative Medicine. 2013, 879512.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • XThe ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability

    King, B., Trimarchi, T., Reavie, L., Xu, L., Mullenders, J., Ntziachristos, P., Aranda-Orgilles, B., Perez-Garcia, A., Shi, J., Vakoc, C., Sandy, P., Shen, S. S., Ferrando, A. & Aifantis, I., Jun 20 2013, In: Cell. 153, 7, p. 1552 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    272 Scopus citations
  • 2012

    [Detection of dynamic expression of microRNAs in vivo using a dual-fluorescence reporter system/miRNA Tracer in zebrafish].

    Yang, H. B., Liang, W., Liu, X. X., Zhu, Z. Y., Lin, S. & Zhang, B., 2012, In: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji. 34, 9, p. 1181-1192 12 p.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • A humanized pattern of aromatase expression is associated with mammary hyperplasia in mice

    Zhao, H., Pearson, E. K., Brooks, D. C., Coon V, J. S., Chen, D., Demura, M., Zhang, M., Clevenger, C. V., Xu, X., Veenstra, T. D., Chatterton, R. T., DeMayo, F. J. & Bulun, S. E., Jun 2012, In: Endocrinology. 153, 6, p. 2701-2713 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities and corepressor interactions

    Morgan, M. A., Mould, A. W., Li, L., Robertson, E. J. & Bikoff, E. K., Sep 2012, In: Molecular and cellular biology. 32, 17, p. 3403-3413 11 p.

    Research output: Contribution to journal › Article › peer-review

    16 Scopus citations

  • A map of the cis-regulatory sequences in the mouse genome

    Shen, Y., Yue, F., Mc Cleary, D. F., Ye, Z., Edsall, L., Kuan, S., Wagner, U., Dixon, J., Lee, L., Ren, B. & Lobanenkov, V. V., Aug 2 2012, In: Nature. 488, 7409, p. 116-120 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1081 Scopus citations

  • Ancestral and conserved cis-regulatory architectures in developmental control genes

    Rebeiz, M., Castro, B., Liu, F., Yue, F. & Posakony, J. W., Feb 15 2012, In: Developmental Biology. 362, 2, p. 282-294 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    14 Scopus citations

  • An encyclopedia of mouse DNA elements (Mouse ENCODE)

    Stamatoyannopoulos, J. A., Snyder, M., Hardison, R., Ren, B., Gingeras, T., Gilbert, D. M., Groudine, M., Bender, M., Kaul, R., Canfield, T., Giste, E., Johnson, A., Zhang, M., Balasundaram, G., Byron, R., Roach, V., Sabo, P. J., Sandstrom, R., Stehling, A. S. & Thurman, R. E. & 66 others, Weissman, S. M., Cayting, P., Hariharan, M., Lian, J., Cheng, Y., Landt, S. G., Ma, Z., Wold, B. J., Dekker, J., Crawford, G. E., Keller, C. A., Wu, W., Morrissey, C., Kumar, S. A., Mishra, T., Jain, D., Byrska-Bishop, M., Blankenberg, D., Lajoiel, B. R., Jain, G., Sanyal, A., Chen, K. B., Denas, O., Taylor, J., Blobel, G. A., Weiss, M. J., Pimkin, M., Deng, W., Marinov, G. K., Williams, B. A., Fisher-Aylor, K. I., Desalvo, G., Kiralusha, A., Trout, D., Amrhein, H., Mortazavi, A., Edsall, L., McCleary, D., Kuan, S., Shen, Y., Yue, F., Ye, Z., Davis, C. A., Zaleski, C., Jha, S., Xue, C., Dobin, A., Lin, W., Fastuca, M., Wang, H., Guigo, R., Djebali, S., Lagarde, J., Ryba, T., Sasaki, T., Malladi, V. S., Cline, M. S., Kirkup, V. M., Learned, K., Rosenbloom, K. R., Kent, W. J., Feingold, E. A., Good, P. J., Pazin, M., Lowdon, R. F. & Adams, L. B., Aug 13 2012, In: Genome biology. 13, 8, 418.

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    362 Scopus citations

  • A new histone at the centromere?

    Foltz, D. R. & Stukenberg, P. T., Feb 3 2012, In: Cell. 148, 3, p. 394-396 3 p.

    Research output: Contribution to journal › Short survey › peer-review

    Open Access
    4 Scopus citations

  • An integrated cytogenetic and physical map reveals unevenly distributed recombination spots along the papaya sex chromosomes

    Wai, C. M., Moore, P. H., Paull, R. E., Ming, R. & Yu, Q., Aug 2012, In: Chromosome Research. 20, 6, p. 753-767 15 p.

    Research output: Contribution to journal › Article › peer-review

    20 Scopus citations

  • A novel chromone derivative with anti-inflammatory property via inhibition of ROS-dependent activation of TRAF6-ASK1-p38 pathway

    Liu, H., Xu, R., Feng, L., Guo, W., Cao, N., Qian, C., Teng, P., Wang, L., Wu, X., Sun, Y., Li, J., Shen, Y. & Xu, Q., Jun 15 2012, In: PloS one. 7, 6, e37168.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    47 Scopus citations

  • A sensing array of radically coupled genetic 'biopixels'

    Prindle, A., Samayoa, P., Razinkov, I., Danino, T., Tsimring, L. S. & Hasty, J., Jan 5 2012, In: Nature. 481, 7379, p. 39-44 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    313 Scopus citations

  • Bacillus anthracis inosine 5′-monophosphate dehydrogenase in action: The first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes

    Makowska-Grzyska, M., Kim, Y., Wu, R., Wilton, R., Gollapalli, D. R., Wang, X. K., Zhang, R., Jedrzejczak, R., MacK, J. C., Maltseva, N., Mulligan, R., Binkowski, T. A., Gornicki, P., Kuhn, M. L., Anderson, W. F., Hedstrom, L. & Joachimiak, A., Aug 7 2012, In: Biochemistry. 51, 31, p. 6148-6163 16 p.

    Research output: Contribution to journal › Article › peer-review

    36 Scopus citations

  • Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome

    Xie, W., Barr, C. L., Kim, A., Yue, F., Lee, A. Y., Eubanks, J., Dempster, E. L. & Ren, B., Feb 17 2012, In: Cell. 148, 4, p. 816-831 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    441 Scopus citations

  • Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data

    Liu, Y., Siegmund, K. D., Laird, P. W. & Berman, B. P., Jul 11 2012, In: Genome biology. 13, 7, R61.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    200 Scopus citations

  • Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta

    Mould, A., Morgan, M. A., Li, L., Bikoff, E. K. & Robertson, E. J., Sep 15 2012, In: Genes and Development. 26, 18, p. 2063-2074 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    62 Scopus citations

  • Cdk Activity Couples Epigenetic Centromere Inheritance to Cell Cycle Progression

    Silva, M. C. C., Bodor, D. L., Stellfox, M. E., Martins, N. M. C., Hochegger, H., Foltz, D. R. & Jansen, L. E. T., Jan 17 2012, In: Developmental Cell. 22, 1, p. 52-63 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    135 Scopus citations

  • Codependency of H2B monoubiquitination and nucleosome reassembly on Chdl

    Lee, J. S., Garrett, A. S., Yen, K., Takahashi, Y. H., Hu, D., Jackson, J., Seidel, C., Franklin Pugh, B. & Shilatifard, A., May 1 2012, In: Genes and Development. 26, 9, p. 914-919 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    60 Scopus citations

  • Comprehensive genomic characterization of squamous cell lung cancers

    Hammerman, P. S., Voet, D., Lawrence, M. S., Voet, D., Jing, R., Cibulskis, K., Sivachenko, A., Stojanov, P., McKenna, A., Lander, E. S., Gabriel, S., Getz, G., Imielinski, M., Helman, E., Hernandez, B., Pho, N. H., Meyerson, M., Chu, A., Hye-Chun, J. E. & Mungall, A. J. & 320 others, Pleasance, E., Robertson, A. G., Sipahimalani, P., Stoll, D., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chuah, E., Coope, R. J. N., Corbett, R., Dhalla, N., Guin, R., He, A., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, K., Nip, K. M., Olshen, A., Schein, J. E., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R., Zeng, T., Zhao, Y., Jones, S. J. M., Marra, M. A., Saksena, G., Cherniack, A. D., Schumacher, S. E., Tabak, B., Carter, S. L., Nguyen, H., Onofrio, R. C., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Protopopov, A., Zhang, J., Hadjipanayis, A., Lee, S., Xi, R., Yang, L., Ren, X., Zhang, H., Shukla, S., Chen, P. C., Haseley, P., Lee, E., Chin, L., Park, P. J., Kucherlapati, R., Socci, N. D., Liang, Y., Schultz, N., Borsu, L., Lash, A. E., Viale, A., Sander, C., Ladanyi, M., Auman, J. T., Hoadley, K. A., Wilkerson, M. D., Shi, Y., Liquori, C., Meng, S., Li, L., Turman, Y. J., Topal, M. D., Tan, D., Waring, S., Buda, E., Walsh, J., Jones, C. D., Mieczkowski, P. A., Singh, D., Wu, J., Gulabani, A., Dolina, P., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Stuart, J., Mose, L. E., Jefferys, S. R., Balu, S., O'Connor, B. D., Chiang, D., Liu, J., Chiang, D. Y., Hayes, D. N., Perou, C. M., Cope, L., Weisenberger, D., Danilova, L., Weisenberger, D. J., Maglinte, D. T., Pan, F., Van Den Berg, D. J., Triche, T., Herman, J. G., Baylin, S. B., Laird, P. W., Noble, M., Gehlenborg, N., DiCara, D., Zhang, J., Wu, C. J., Liu, S. Y., Zou, L., Lin, P., Cho, J., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Sinha, R., Ciriello, G., Cerami, E., Gross, B., Jacobsen, A., Gao, J., Aksoy, B. A., Weinhold, N., Ramirez, R., Taylor, B. S., Antipin, Y., Reva, B., Mo, Q., Seshan, V., Paik, P. K., Akbani, R., Zhang, N., Broom, B. M., Casasent, T., Unruh, A., Wakefield, C., Cason, R. C., Baggerly, K. A., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Ng, S., Goldstein, T., Waltman, P., Sokolov, A., Collisson, E., Ellrott, K., Collisson, E. A., Zerbino, D., Ma, S., Craft, B., Du, Y., Cabanski, C., Walter, V., Marron, J. S., Liu, Y., Wang, K., Prins, J. F., Creighton, C. J., Zhang, Y., Travis, W. D., Rekhtman, N., Yi, J., Aubry, M. C., Cheney, R., Dacic, S., Flieder, D., Funkhouser, W., Illei, P., Myers, J., Tsao, M. S., Penny, R., Mallery, D., Shelton, T., Hatfield, M., Morris, S., Yena, P., Shelton, C., Sherman, M., Paulauskis, J., Govindan, R., Azodo, I., Beer, D., Bose, R., Byers, L. A., Carbone, D., Chang, L. W., Chun, E., Ding, L., Heymach, J., Ida, C., Johnson, B., Jurisica, I., Kaufman, J., Kosari, F., Kwiatkowski, D., Maher, C. A., Mungall, A., Pao, W., Peifer, M., Robertson, G., Rusch, V., Siegfried, J., Sougnez, C., Thomas, R. K., Tomaszek, S., Vaske, C., Wheeler, D., Wigle, D. A., Wilks, C., Zhang, J. J., Jensen, M. A., Sfeir, R., Kahn, A. B., Chu, A. L., Kothiyal, P., Wang, Z., Snyder, E. E., Pontius, J., Pihl, T. D., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D. L., Nicholls, M. C., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P. A., Alonso, S., Sanbhadti, R. N., Barletta, S. P., Greene, J. M., Pot, D. A., Bandarchi-Chamkhaleh, B., Boyd, J., Weaver, J., Azodo, I. A., Tomaszek, S. C., Aubry, M. C., Ida, C. M., Yang, P., Brock, M. V., Rogers, K., Rutledge, M., Brown, T., Lee, B., Shin, J., Trusty, D., Dhir, R., Siegfried, J. M., Potapova, O., Fedosenko, K. V., Nemirovich-Danchenko, E., Zakowski, M., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Fan, Z., Todaro, N., Eckman, J., Rathmell, W. K., Thorne, L. B., Huang, M., Boice, L., Hill, A., Curley, E., Morrison, C., Gaudioso, C., Bartlett, J. M. S., Kodeeswaran, S., Zanke, B., Sekhon, H., David, K., Juhl, H., Le, X. V., Kohl, B., Thorp, R., Tien, N. V., Bang, N. V., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Khan, K. Z., Muley, T., Mills Shaw, K. R., Sheth, M., Yang, L., Buetow, K., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M., Dillon, L. A. L., Schaefer, C., Guyer, M. S., Ozenberger, B. A., Palchik, J. D., Peterson, J., Sofia, H. J., Thomson, E., Johnson, B. E. & Shen, R., Sep 27 2012, In: Nature. 489, 7417, p. 519-525 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3279 Scopus citations

  • Comprehensive molecular portraits of human breast tumours

    Koboldt, D. C., Fulton, R. S., McLellan, M. D., Schmidt, H., Kalicki-Veizer, J., McMichael, J. F., Fulton, L. L., Dooling, D. J., Ding, L., Mardis, E. R., Wilson, R. K., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E. & Coope, R. J. N. & 323 others, Dhalla, N., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Pleasance, E., Robertson, A. G., Schein, J. E., Shafiei, A., Sipahimalani, P., Slobodan, J. R., Stoll, D., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zeng, T., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Cherniack, A. D., Saksena, G., Onofrio, R. C., Pho, N. H., Carter, S. L., Schumacher, S. E., Tabak, B., Hernandez, B., Gentry, J., Nguyen, H., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Getz, G., Gabriel, S. B., Meyerson, M., Chin, L., Kucherlapati, R., Hoadley, K. A., Auman, J. T., Fan, C., Turman, Y. J., Shi, Y., Li, L., Topal, M. D., He, X., Chao, H. H., Prat, A., Silva, G. O., Iglesia, M. D., Zhao, W., Usary, J., Berg, J. S., Adams, M., Booker, J., Wu, J., Gulabani, A., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Mose, L. E., Jefferys, S. R., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Malik, S., Mahurkar, S., Shen, H., Weisenberger, D. J., Triche, T., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Berman, B. P., Van Den Berg, D. J., Baylin, S. B., Laird, P. W., Creighton, C. J., Donehower, L. A., Noble, M., Voet, D., Gehlenborg, N., Di Cara, D., Zhang, J., Zhang, H., Wu, C. J., Yingchun Liu, S., Lawrence, M. S., Zou, L., Sivachenko, A., Lin, P., Stojanov, P., Jing, R., Cho, J., Sinha, R., Park, R. W., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Park, P. J., Reynolds, S., Kreisberg, R. B., Bernard, B., Bressler, R., Erkkila, T., Lin, J., Thorsson, V., Zhang, W., Shmulevich, I., Ciriello, G., Weinhold, N., Schultz, N., Gao, J., Cerami, E., Gross, B., Jacobsen, A., Sinha, R., Aksoy, B. A., Antipin, Y., Reva, B., Shen, R., Taylor, B. S., Ladanyi, M., Sander, C., Anur, P., Spellman, P. T., Lu, Y., Liu, W., Verhaak, R. R. G., Mills, G. B., Akbani, R., Zhang, N., Broom, B. M., Casasent, T. D., Wakefield, C., Unruh, A. K., Baggerly, K., Coombes, K., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Zhu, J., Szeto, C. C., Scott, G. K., Yau, C., Paull, E. O., Carlin, D., Wong, C., Sokolov, A., Thusberg, J., Mooney, S., Ng, S., Goldstein, T. C., Ellrott, K., Grifford, M., Wilks, C., Ma, S., Craft, B., Yan, C., Hu, Y., Meerzaman, D., Gastier-Foster, J. M., Bowen, J., Ramirez, N. C., Black, A. D., Pyatt, R. E., White, P., Zmuda, E. J., Frick, J., Lichtenberg, T. M., Brookens, R., George, M. M., Gerken, M. A., Harper, H. A., Leraas, K. M., Wise, L. J., Tabler, T. R., McAllister, C., Barr, T., Hart-Kothari, M., Tarvin, K., Saller, C., Sandusky, G., Mitchell, C., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Dolzhansky, O., Abramov, M., Voronina, O., Potapova, O., Marks, J. R., Suchorska, W. M., Murawa, D., Kycler, W., Ibbs, M., Korski, K., Spychała, A., Murawa, P., Brzeziński, J. J., Perz, H., Łaźniak, R., Teresiak, M., Tatka, H., Leporowska, E., Bogusz-Czerniewicz, M., Malicki, J., Mackiewicz, A., Wiznerowicz, M., Van Le, X., Kohl, B., Viet Tien, N., Thorp, R., Van Bang, N., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Phuong, T. V. T., Thang, H. Q., Khan, K. Z., Penny, R., Mallery, D., Curley, E., Shelton, C., Yena, P., Ingle, J. N., Couch, F. J., Lingle, W. L., King, T. A., Gonzalez-Angulo, A. M., Dyer, M. D., Liu, S., Meng, X., Patangan, M., Waldman, F., Stöppler, H., Rathmell, W. K., Thorne, L., Huang, M., Boice, L., Hill, A., Morrison, C., Gaudioso, C., Bshara, W., Daily, K., Egea, S. C., Pegram, M. D., Gomez-Fernandez, C., Dhir, R., Bhargava, R., Brufsky, A., Shriver, C. D., Hooke, J. A., Campbell, J. L., Mural, R. J., Hu, H., Somiari, S., Larson, C., Deyarmin, B., Kvecher, L., Kovatich, A. J., Ellis, M. J., Stricker, T., White, K., Olopade, O., Luo, C., Chen, Y., Bose, R., Chang, L. W., Beck, A. H., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Wang, Z., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Shaw, K. R. M., Yang, L., Eley, G., Ferguson, M. L., Tarnuzzer, R. W., Zhang, J., Dillon, L. A. L., Buetow, K., Fielding, P., Ozenberger, B. A., Guyer, M. S., Sofia, H. J. & Palchik, J. D., Oct 4 2012, In: Nature. 490, 7418, p. 61-70 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9569 Scopus citations

  • Determination of phenobarbital in human urine and serum using flow injection chemiluminescence

    Li, X., Niu, L. C., He, X. L. & Song, Z. H., 2012, In: Biomeditsinskaya Khimiya. 58, 1, p. 88-94 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Direct observation of nanoparticle-cancer cell nucleus interactions

    Dam, D. H. M., Lee, J. H., Sisco, P. N., Co, D. T., Zhang, M., Wasielewski, M. R. & Odom, T. W., Apr 24 2012, In: ACS nano. 6, 4, p. 3318-3326 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    257 Scopus citations

  • Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

    Lohr, J. G., Stojanov, P., Lawrence, M. S., Auclair, D., Chapuy, B., Sougnez, C., Cruz-Gordillo, P., Knoechel, B., Asmann, Y. W., Slager, S. L., Novak, A. J., Dogan, A., Ansell, S. M., Link, B. K., Zou, L., Gould, J., Saksena, G., Stransky, N., Rangel-Escareño, C. & Fernandez-Lopez, J. C. & 14 others, Hidalgo-Miranda, A., Melendez-Zajgla, J., Hernández-Lemus, E., Schwarz-Cruz y Celis, A., Imaz-Rosshandler, I., Ojesina, A. I., Jung, J., Pedamallu, C. S., Lander, E. S., Habermann, T. M., Cerhan, J. R., Shipp, M. A., Getz, G. & Golub, T. R., Mar 6 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3879-3884 6 p.

    Research output: Contribution to journal › Article › peer-review

    831 Scopus citations

  • Enhancer-associated H3K4 monomethylation by trithorax-related, the drosophila homolog of mammalian MLL3/MLL4

    Herz, H. M., Mohan, M., Garruss, A. S., Liang, K., Takahashi, Y. H., Mickey, K., Voets, O., Verrijzer, C. P. & Shilatifard, A., Dec 2012, In: Genes and Development. 26, 23, p. 2604-2620 17 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    310 Scopus citations

  • Environmental Regulation of Prions in Yeast

    Li, L. & Kowal, A. S., Nov 2012, In: PLoS pathogens. 8, 11, e1002973.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

    Ntziachristos, P., Tsirigos, A., Vlierberghe, P. V., Nedjic, J., Trimarchi, T., Flaherty, M. S., Ferres-Marco, D., Da Ros, V., Tang, Z., Siegle, J., Asp, P., Hadler, M., Rigo, I., De Keersmaecker, K., Patel, J., Huynh, T., Utro, F., Poglio, S., Samon, J. B. & Paietta, E. & 9 others, Racevskis, J., Rowe, J. M., Rabadan, R., Levine, R. L., Brown, S., Pflumio, F., Dominguez, M., Ferrando, A. & Aifantis, I., 2012, In: Nature Medicine. 18, 2, p. 296-301 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    439 Scopus citations

  • Genome sequences of the primary endosymbiont "Candidatus portiera aleyrodidarum" in the whitefly Bemisia tabaci B and Q biotypes

    Jiang, Z. F., Xia, F., Johnson, K. W., Bartom, E., Tuteja, J. H., Stevens, R., Grossman, R. L., Brumin, M., White, K. P. & Ghanim, M., Dec 2012, In: Journal of bacteriology. 194, 23, p. 6678-6679 2 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    26 Scopus citations

  • Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules

    Kelly, T. K., Liu, Y., Lay, F. D., Liang, G., Berman, B. P. & Jones, P. A., Dec 2012, In: Genome research. 22, 12, p. 2497-2506 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    352 Scopus citations

  • Genomic profiling of rice sperm cell transcripts reveals conserved and distinct elements in the flowering plant male germ lineage

    Russell, S. D., Gou, X., Wong, C. E., Wang, X., Yuan, T., Wei, X., Bhalla, P. L. & Singh, M. B., Aug 2012, In: New Phytologist. 195, 3, p. 560-573 14 p.

    Research output: Contribution to journal › Article › peer-review

    57 Scopus citations

  • Gonadotropin-releasing hormone analogue multiple injection potentially accelerated testicular maturation of male yellow catfish (Pelteobagrus fluvidraco, Richardson) in captivity

    Zhuo, Q., Zhang, Y., Huang, W., Liu, X., Li, Y., Zhu, P., Lu, D. & Lin, H., Feb 2012, In: Aquaculture Research. 43, 3, p. 467-480 14 p.

    Research output: Contribution to journal › Article › peer-review

    3 Scopus citations

  • Hijacking T Cell Differentiation: New Insights in TLX Function in T-ALL

    King, B., Ntziachristos, P. & Aifantis, I., Apr 17 2012, In: Cancer cell. 21, 4, p. 453-455 3 p.

    Research output: Contribution to journal › Short survey › peer-review

    Open Access
    1 Scopus citations

  • HJURP Uses Distinct CENP-A Surfaces to Recognize and to Stabilize CENP-A/Histone H4 for Centromere Assembly

    Bassett, E. A., DeNizio, J., Barnhart-Dailey, M. C., Panchenko, T., Sekulic, N., Rogers, D. J., Foltz, D. R. & Black, B. E., Apr 17 2012, In: Developmental Cell. 22, 4, p. 749-762 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    96 Scopus citations

  • HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

    Mendillo, M. L., Santagata, S., Koeva, M., Bell, G. W., Hu, R., Tamimi, R. M., Fraenkel, E., Ince, T. A., Whitesell, L. & Lindquist, S., Aug 3 2012, In: Cell. 150, 3, p. 549-562 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    543 Scopus citations

  • Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL

    Wen, Q., Goldenson, B., Silver, S. J., Schenone, M., Dancik, V., Huang, Z., Wang, L. Z., Lewis, T. A., An, W. F., Li, X., Bray, M. A., Thiollier, C., Diebold, L., Gilles, L., Vokes, M. S., Moore, C. B., Bliss-Moreau, M., Verplank, L., Tolliday, N. J. & Mishra, R. & 28 others, Vemula, S., Shi, J., Wei, L., Kapur, R., Lopez, C. K., Gerby, B., Ballerini, P., Pflumio, F., Gilliland, D. G., Goldberg, L., Birger, Y., Izraeli, S., Gamis, A. S., Smith, F. O., Woods, W. G., Taub, J., Scherer, C. A., Bradner, J. E., Goh, B. C., Mercher, T., Carpenter, A. E., Gould, R. J., Clemons, P. A., Carr, S. A., Root, D. E., Schreiber, S. L., Stern, A. M. & Crispino, J. D., Aug 3 2012, In: Cell. 150, 3, p. 575-589 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    127 Scopus citations

  • Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness

    Puissant, A., Dufies, M., Fenouille, N., Ben Sahra, I., Jacquel, A., Robert, G., Cluzeau, T., Deckert, M., Tichet, M., Chéli, Y., Cassuto, J. P., Raynaud, S., Legros, L., Pasquet, J. M., Mahon, F. X., Luciano, F. & Auberger, P., Aug 2012, In: Journal of molecular cell biology. 4, 4, p. 207-220 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Making gene circuits sing

    Prindle, A. & Hasty, J., Oct 16 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 42, p. 16758-16759 2 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    4 Scopus citations