Center for Molecular Innovation and Drug Discovery

Fingerprint Dive into the research topics where Center for Molecular Innovation and Drug Discovery is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Fullerenes Chemical Compounds
Molecules Chemical Compounds
Ligands Medicine & Life Sciences
Palladium Chemical Compounds
Quantitative Structure-Activity Relationship Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Phosphotransferases Chemical Compounds
Fluorination Chemical Compounds

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Research Output 1988 2019

A novel strategy to block mitotic progression for targeted therapy

Chi, J. J., Li, H., Zhou, Z., Izquierdo-Ferrer, J., Xue, Y., Wavelet, C. M., Schiltz, G. E., Zhang, B., Cristofanilli, M., Lu, X., Bahar, I. & Wan, Y., Nov 2019, In : EBioMedicine. 49, p. 40-54 15 p.

Research output: Contribution to journalArticle

Open Access
Degradation
Tumors
Cells
Neoplasms
Breast Neoplasms

Development of Tetrahydroindazole-Based Potent and Selective Sigma-2 Receptor Ligands

Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., Jul 3 2019, In : ChemMedChem. 14, 13, p. 1248-1256 9 p.

Research output: Contribution to journalArticle

Drug Discovery
Ligands
Central Nervous System Diseases
Neurology
Solubility
2 Citations (Scopus)

Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands

Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Protein Transport
Ligands
Molecular modeling
Central Nervous System Diseases
Structure-Activity Relationship

Grants 2011 2024

Neoplasms
Therapeutics
Bone Marrow Diseases
Mutation
Hematopoiesis
Neuropharmacology
Pharmaceutical Preparations
Ligands
Technology
Neurobiology