Center for Molecular Innovation and Drug Discovery

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Fullerenes Chemical Compounds
Molecules Chemical Compounds
Palladium Chemical Compounds
Ligands Medicine & Life Sciences
Quantitative Structure-Activity Relationship Medicine & Life Sciences
Fluorination Chemical Compounds
Fluorides Chemical Compounds
Hydrocarbons Chemical Compounds

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Profiles

No photo of Rama K Mishra

Rama K Mishra

Person: Academic

19882020
No photo of Karl A Scheidt
19982023

Research Output 1988 2019

Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands

Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Protein Transport
Ligands
Molecular modeling
Central Nervous System Diseases
Structure-Activity Relationship
1 Citation (Scopus)

Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments

Chowdhury, S. R., Kennedy, S., Zhu, K., Mishra, R. K., Chuong, P., Nguyen, A. U., Kathman, S. G. & Statsyuk, A. V., Jan 1 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 36-39 4 p.

Research output: Contribution to journalArticle

Cysteine Proteinase Inhibitors
Cathepsin L
Cathepsin B
Enzyme Inhibitors
Peptide Hydrolases
Fluorine
Palladium
Bioactivity
Biological Products
Scaffolds

Grants 2011 2023

Neoplasms
Therapeutics
Bone Marrow Diseases
Mutation
Hematopoiesis
Neuropharmacology
Pharmaceutical Preparations
Ligands
Technology
Neurobiology
Kidney
Kidney Diseases
Research Personnel
Therapeutics
Nanomedicine