CLP - Chemistry of Life Processes Institute

Research Output

  • 70 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Comment/debate
2020

Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy

Sheibani, N., Zaitoun, I. S., Wang, S., Darjatmoko, S. R., Suscha, A., Song, Y. S., Sorenson, C. M., Shifrin, V., Albert, D. M., Melgar-Asensio, I., Kandela, I. & Henkin, J., Jun 2020, In : Experimental eye research. 195, 108030.

Research output: Contribution to journalArticle

Self-Immolative Activation of β-Galactosidase-Responsive Probes for In Vivo MR Imaging in Mouse Models

Lilley, L. M., Kamper, S., Caldwell, M., Chia, Z. K., Ballweg, D., Vistain, L., Krimmel, J., Mills, T. A., MacRenaris, K., Lee, P., Waters, E. A. & Meade, T. J., Jan 2 2020, In : Angewandte Chemie - International Edition. 59, 1, p. 388-394 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2019

Bioresorbable photonic devices for the spectroscopic characterization of physiological status and neural activity

Bai, W., Shin, J., Fu, R., Kandela, I., Lu, D., Ni, X., Park, Y., Liu, Z., Hang, T., Wu, D., Liu, Y., Haney, C. R., Stepien, I., Yang, Q., Zhao, J., Nandoliya, K. R., Zhang, H., Sheng, X., Yin, L., MacRenaris, K. & 6 others, Brikha, A., Aird, F., Pezhouh, M., Hornick, J., Zhou, W. & Rogers, J. A., Aug 1 2019, In : Nature Biomedical Engineering. 3, 8, p. 644-654 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2018

A Markedly Improved Synthetic Approach for the Preparation of Multifunctional Au-DNA Nanoparticle Conjugates Modified with Optical and MR Imaging Probes

Rotz, M. W., Holbrook, R. J., Macrenaris, K. W. & Meade, T. J., Nov 21 2018, In : Bioconjugate Chemistry. 29, 11, p. 3544-3549 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Catalytically Active Silicon Oxide Nanoclusters Stabilized in a Metal–Organic Framework

Rimoldi, M., Gallington, L. C., Chapman, K. W., MacRenaris, K., Hupp, J. T. & Farha, O. K., Jun 22 2017, In : Chemistry - A European Journal. 23, 35, p. 8532-8536 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exploring the Association between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel

Wong, W. P., Allen, N. B., Meyers, M. S., Link, E. O., Zhang, X., MacRenaris, K. W. & El Muayed, M., Dec 1 2017, In : Scientific reports. 7, 1, 473.

Research output: Contribution to journalArticle

15 Scopus citations

Gd(III)-gold nanoconjugates provide remarkable cell labeling for high field magnetic resonance imaging

Rammohan, N., Holbrook, R. J., Rotz, M. W., MacRenaris, K. W., Preslar, A. T., Carney, C. E., Reichova, V. & Meade, T. J., Jan 1 2017, In : Bioconjugate Chemistry. 28, 1, p. 153-160 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Synthesis and evaluation of MR probes for targeted-reporter imaging

Verma, K. D., Massing, J. O., Kamper, S. G., Carney, C. E., Macrenaris, K. W., Basilion, J. P. & Meade, T. J., Jan 1 2017, In : Chemical Science. 8, 8, p. 5764-5768 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast Agent

Macrenaris, K. W., Ma, Z., Krueger, R. L., Carney, C. E. & Meade, T. J., Feb 17 2016, In : Bioconjugate Chemistry. 27, 2, p. 465-473 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells

Nicholls, F. J., Rotz, M. W., Ghuman, H., MacRenaris, K. W., Meade, T. J. & Modo, M., Jan 1 2016, In : Biomaterials. 77, p. 291-306 16 p.

Research output: Contribution to journalArticle

52 Scopus citations

Gd(III)-Dithiolane Gold Nanoparticles for T1-Weighted Magnetic Resonance Imaging of the Pancreas

Holbrook, R. J., Rammohan, N., Rotz, M. W., Macrenaris, K. W., Preslar, A. T. & Meade, T. J., May 11 2016, In : Nano letters. 16, 5, p. 3202-3209 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

In situ biomineralization and particle deposition distinctively mediate biofilm susceptibility to chlorine

Li, X., Chopp, D. L., Russin, W. A., Brannon, P. T., Parsek, M. R. & Packman, A. I., May 1 2016, In : Applied and Environmental Microbiology. 82, 10, p. 2886-2892 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nanodiamond-Gadolinium(III) Aggregates for Tracking Cancer Growth in Vivo at High Field

Rammohan, N., MacRenaris, K. W., Moore, L. K., Parigi, G., Mastarone, D. J., Manus, L. M., Lilley, L. M., Preslar, A. T., Waters, E. A., Filicko, A., Luchinat, C., Ho, D. & Meade, T. J., Dec 14 2016, In : Nano letters. 16, 12, p. 7551-7564 14 p.

Research output: Contribution to journalArticle

31 Scopus citations
2015

Amorphous intergranular phases control the properties of rodent tooth enamel

Gordon, L. M., Cohen, M. J., MacRenaris, K. W., Pasteris, J. D., Seda, T. & Joester, D., Feb 13 2015, In : Science. 347, 6223, p. 746-750 5 p.

Research output: Contribution to journalArticle

85 Scopus citations

Erratum: To Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization in Vivo(ACS Nano (2014) 8 (7325-7332) DOI: 10.1021/nn502393u)

Preslar, A. T., Parigi, G., McClendon, M. T., Sefick, S. S., Moyer, T. J., Haney, C. R., Waters, E. A., MacRenaris, K. W., Luchinat, C., Stupp, S. I. & Meade, T. J., Nov 24 2015, In : ACS nano. 9, 11, 1 p.

Research output: Contribution to journalComment/debate

High relaxivity Gd(III)-DNA gold nanostars: Investigation of shape effects on proton relaxation

Rotz, M. W., Culver, K. S. B., Parigi, G., Macrenaris, K. W., Luchinat, C., Odom, T. W. & Meade, T. J., Mar 24 2015, In : ACS nano. 9, 3, p. 3385-3396 12 p.

Research output: Contribution to journalArticle

60 Scopus citations

Investigation of the optical response of photonic crystal nanocavities in ferroelectric oxide thin film

Lin, P. T., Russin, W. A., Joshi-Imre, A., Ocola, L. E. & Wessels, B. W., Sep 4 2015, In : Journal of Optics (United Kingdom). 17, 10, 105402.

Research output: Contribution to journalArticle

2 Scopus citations

Multimeric Near IR-MR Contrast Agent for Multimodal in Vivo Imaging

Harrison, V. S. R., Carney, C. E., Macrenaris, K. W., Waters, E. A. & Meade, T. J., Jul 22 2015, In : Journal of the American Chemical Society. 137, 28, p. 9108-9116 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Nanodiscs as a modular platform for multimodal MR-optical imaging

Carney, C. E., Lenov, I. L., Baker, C. J., Macrenaris, K. W., Eckermann, A. L., Sligar, S. G. & Meade, T. J., May 20 2015, In : Bioconjugate Chemistry. 26, 5, p. 899-905 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Spatial patterns of carbonate biomineralization in biofilms

Li, X., Chopp, D. L., Russin, W. A., Brannon, P. T., Parsek, M. R. & Packman, A. I., Jan 1 2015, In : Applied and Environmental Microbiology. 81, 21, p. 7403-7410 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease

Viola, K. L., Sbarboro, J., Sureka, R., De, M., Bicca, M. A., Wang, J., Vasavada, S., Satpathy, S., Wu, S., Joshi, H., Velasco, P. T., Macrenaris, K. W., Waters, E. A., Lu, C., Phan, J., Lacor, P., Prasad, P., Dravid, V. P. & Klein, W. L., Jan 1 2015, In : Nature nanotechnology. 10, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

90 Scopus citations

Water-soluble lipophilic MR contrast agents for cell membrane labeling

Carney, C. E., MacRenaris, K. W. & Meade, T. J., Sep 24 2015, In : Journal of Biological Inorganic Chemistry. 20, 6, p. 971-977 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

A multimeric MR-optical contrast agent for multimodal imaging

Harrison, V. S. R., Carney, C. E., Macrenaris, K. W. & Meade, T. J., Oct 9 2014, In : Chemical Communications. 50, 78, p. 11469-11471 3 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cell labeling via membrane-anchored lipophilic MR contrast agents

Carney, C. E., Macrenaris, K. W., Mastarone, D. J., Kasjanski, D. R., Hung, A. H. & Meade, T. J., May 21 2014, In : Bioconjugate Chemistry. 25, 5, p. 945-954 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Gd(III)-labeled peptide nanofibers for reporting on biomaterial localization in vivo

Preslar, A. T., Parigi, G., McClendon, M. T., Sefick, S. S., Moyer, T. J., Haney, C. R., Waters, E. A., Macrenaris, K. W., Luchinat, C., Stupp, S. & Meade, T. J., Jul 22 2014, In : ACS nano. 8, 7, p. 7325-7332 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Graphene oxide enhances cellular delivery of hydrophilic small molecules by co-incubation

Hung, A. H., Holbrook, R. J., Rotz, M. W., Glasscock, C. J., Mansukhani, N. D., Macrenaris, K. W., Manus, L. M., Duch, M. C., Dam, K. T., Hersam, M. C. & Meade, T. J., Oct 28 2014, In : ACS nano. 8, 10, p. 10168-10177 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Progesterone-targeted magnetic resonance imaging probes

Townsend, T. R., Moyle-Heyrman, G., Sukerkar, P. A., MacRenaris, K. W., Burdette, J. E. & Meade, T. J., Aug 20 2014, In : Bioconjugate Chemistry. 25, 8, p. 1428-1437 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Synthesis and characterization of a porphyrazine-Gd(III) MRI contrast agent and in vivo imaging of a breast cancer xenograft model

Trivedi, E. R., Ma, Z., Waters, E. A., Macrenaris, K. W., Subramanian, R., Barrett, A. G. M., Meade, T. J. & Hoffman, B. M., Jan 1 2014, In : Contrast Media and Molecular Imaging. 9, 4, p. 313-322 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2013

Mechanisms of gadographene-mediated proton spin relaxation

Hung, A. H., Duch, M. C., Parigi, G., Rotz, M. W., Manus, L. M., Mastarone, D. J., Dam, K. T., Gits, C. C., MacRenaris, K. W., Luchinat, C., Hersam, M. C. & Meade, T. J., Aug 8 2013, In : Journal of Physical Chemistry C. 117, 31, p. 16263-16273 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

PH-responsive theranostic polymer-caged nanobins: Enhanced cytotoxicity and T1 MRI contrast by Her2 targeting

Hong, B. J., Swindell, E. P., MacRenaris, K. W., Hankins, P. L., Chipre, A. J., Mastarone, D. J., Ahn, R. W., Meade, T. J., O'Halloran, T. V. & Nguyen, S. T., Sep 2013, In : Particle and Particle Systems Characterization. 30, 9, p. 770-774 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Structural optimization of Zn(II)-activated magnetic resonance imaging probes

Matosziuk, L. M., Leibowitz, J. H., Heffern, M. C., Macrenaris, K. W., Ratner, M. A. & Meade, T. J., Nov 4 2013, In : Inorganic chemistry. 52, 21, p. 12250-12261 12 p.

Research output: Contribution to journalArticle

24 Scopus citations
2012

Accumulation of cadmium in insulin-producing β cells

Muayed, M. E., Raja, M. R., Zhang, X., MacRenaris, K. W., Bhatt, S., Chen, X., Urbanek, M., O'Halloran, T. V. & Lowe, W. L., Nov 2012, In : Islets. 4, 6, p. 405-416 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Synthesis, characterization, and in vitro testing of a bacteria-targeted MR contrast agent

Matosziuk, L. M., Harney, A. S., MacRenaris, K. W. & Meade, T. J., Apr 1 2012, In : European Journal of Inorganic Chemistry. 12, p. 2099-2107 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

A steroid-conjugated magnetic resonance probe enhances contrast in progesterone receptor expressing organs and tumors in vivo

Sukerkar, P. A., MacRenaris, K. W., Meade, T. J. & Burdette, J. E., Aug 1 2011, In : Molecular Pharmaceutics. 8, 4, p. 1390-1400 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Polystyrene microsphere-ferritin conjugates: A robust phantom for correlation of relaxivity and size distribution

Sukerkar, P. A., Rezvi, U. G., Macrenaris, K. W., Patel, P. C., Wood, J. C. & Meade, T. J., Feb 1 2011, In : Magnetic Resonance in Medicine. 65, 2, p. 522-530 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Probing the chemical stability of mixed ferrites: Implications for magnetic resonance contrast agent design

Schultz-Sikma, E. A., Joshi, H. M., Ma, Q., Macrenaris, K. W., Eckermann, A. L., Dravid, V. P. & Meade, T. J., May 24 2011, In : Chemistry of Materials. 23, 10, p. 2657-2664 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Synthesis and biological evaluation of water-soluble progesterone- conjugated probes for magnetic resonance imaging of hormone related cancers

Sukerkar, P. A., Macrenaris, K. W., Townsend, T. R., Ahmed, R. A., Burdette, J. E. & Meade, T. J., Nov 16 2011, In : Bioconjugate Chemistry. 22, 11, p. 2304-2316 13 p.

Research output: Contribution to journalArticle

31 Scopus citations
2010

Gd(III)-nanodiamond conjugates for MRI contrast enhancement

Manus, L. M., Mastarone, D. J., Waters, E. A., Zhang, X. Q., Schultz-Sikma, E. A., MacRenaris, K. W., Ho, D. & Meade, T. J., Feb 10 2010, In : Nano letters. 10, 2, p. 484-489 6 p.

Research output: Contribution to journalArticle

237 Scopus citations

Highly dispersible, superparamagnetic magnetite nanoflowers for magnetic resonance imaging

Hu, F., Macrenaris, K. W., A. Waters, E., Schultz-Sikma, E. A., Eckermann, A. L. & Meade, T. J., Jan 1 2010, In : Chemical Communications. 46, 1, p. 73-75 3 p.

Research output: Contribution to journalArticle

94 Scopus citations

Modular polymer-caged nanobins as a theranostic platform with enhanced magnetic resonance relaxivity and pH-responsive drug release

Lee, S. M., Song, Y., Hong, B. J., Macrenaris, K. W., Mastarone, D. J., O'Halloran, T. V., Meade, T. J. & Nguyen, S., Dec 17 2010, In : Angewandte Chemie - International Edition. 49, 51, p. 9960-9964 5 p.

Research output: Contribution to journalArticle

46 Scopus citations
2009

Ferroelectric thin film microcavities and their optical resonant properties

Lin, P. T., Russin, W. A., Imre, A., Ocola, L. E. & Wessels, B. W., 2009, Materials for Nanophotonics - Plasmonics, Metamaterials and Light Localization. Materials Research Society, p. 21-26 6 p. (Materials Research Society Symposium Proceedings; vol. 1182).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Multimodal gadolinium-enriched DNA-gold nanoparticle conjugates for cellular imaging

Song, Y., Xu, X., MacRenaris, K. W., Zhang, X. Q., Mirkin, C. A. & Meade, T. J., Nov 16 2009, In : Angewandte Chemie - International Edition. 48, 48, p. 9143-9147 5 p.

Research output: Contribution to journalArticle

138 Scopus citations

Ultrasmall, water-soluble magnetite nanoparticles with high relaxivity for magnetic resonance imaging

Hu, F., MacRenaris, K. W., Waters, E. A., Liang, T., Schultz-Sikma, E. A., Eckermann, A. L. & Meade, T. J., Dec 1 2009, In : Journal of Physical Chemistry C. 113, 49, p. 20855-20860 6 p.

Research output: Contribution to journalArticle

109 Scopus citations
2008

A novel cholic acid-based contrast enhancement agent for targeted MRI

Chong, H. S., Song, H. A., Lim, S., Macrenaris, K., Ma, X., Lee, H., Bui, P. & Meade, T., Apr 1 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 7, p. 2505-2508 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cell-permeable MR contrast agents with increased intracellular retention

Endres, P. J., MacRenaris, K. W., Vogt, S. & Meade, T. J., Oct 1 2008, In : Bioconjugate Chemistry. 19, 10, p. 2049-2059 11 p.

Research output: Contribution to journalArticle

47 Scopus citations
2007

Rational Design, Synthesis, and Biological Evaluation of Progesterone-Modified MRI Contrast Agents

Lee, J., Burdette, J. E., MacRenaris, K. W., Mustafi, D., Woodruff, T. K. & Meade, T. J., Jul 30 2007, In : Chemistry and Biology. 14, 7, p. 824-834 11 p.

Research output: Contribution to journalArticle

33 Scopus citations
2006

Multifunctional polymeric nanoparticles from diverse bioactive agents

Bertin, P. A., Gibbs, J. M., Shen, C. K. F., Thaxton, C. S., Russin, W. A., Mirkin, C. A. & Nguyen, S. T., Apr 5 2006, In : Journal of the American Chemical Society. 128, 13, p. 4168-4169 2 p.

Research output: Contribution to journalArticle

86 Scopus citations

Quantitative imaging of cell-permeable magnetic resonance contrast agents using X-ray fluorescence

Endres, P. J., MacRenaris, K. W., Vogt, S., Allen, M. J. & Meade, T. J., Oct 1 2006, In : Molecular Imaging. 5, 4, p. 485-497 13 p.

Research output: Contribution to journalArticle

27 Scopus citations
2005

A novel mechanism for protein delivery: Granzyme B undergoes electrostatic exchange from serglycin to target cells

Raja, S. M., Metkar, S. S., Höning, S., Wang, B., Russin, W. A., Pipalia, N. H., Menaa, C., Belting, M., Cao, X., Dressel, R. & Froelich, C. J., May 27 2005, In : Journal of Biological Chemistry. 280, 21, p. 20752-20761 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
2004

Cellular delivery of MRI contrast agents

Allen, M. J., MacRenaris, K. W., Venkatasubramanian, P. N. & Meade, T. J., Mar 1 2004, In : Chemistry and Biology. 11, 3, p. 301-307 7 p.

Research output: Contribution to journalArticle

70 Scopus citations