Life Sciences Graduate Programs

Research Output

2013

Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry

Mutharasan, P., Galdones, E., Bernabé, B. P., Garcia, O. A., Jafari, N., Shea, L. D., Woodruff, T. K., Legro, R. S., Dunaif, A. & Urbanek, M., Jan 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 1, p. E185-E190

Research output: Contribution to journalArticle

85 Scopus citations

Follicle microenvironment-associated alterations in gene expression in the mouse oocyte and its polar body

Jiao, Z. X. & Woodruff, T. K., Apr 2013, In : Fertility and Sterility. 99, 5, p. 1453-1459e1

Research output: Contribution to journalArticle

9 Scopus citations

Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia

Glass, C., Wuertzer, C., Cui, X., Bi, Y., Davuluri, R., Xiao, Y. Y., Wilson, M., Owens, K., Zhang, Y. & Perkins, A., Jun 27 2013, In : PloS one. 8, 6, e67134.

Research output: Contribution to journalArticle

32 Scopus citations

HINCUTs in cancer: Hypoxia-induced noncoding ultraconserved transcripts

Ferdin, J., Nishida, N., Wu, X., Nicoloso, M. S., Shah, M. Y., Devlin, C., Ling, H., Shimizu, M., Kumar, K., Cortez, M. A., Ferracin, M., Bi, Y., Yang, D., Czerniak, B., Zhang, W., Schmittgen, T. D., Voorhoeve, M. P., Reginato, M. J., Negrini, M., Davuluri, R. V. & 3 others, Kunej, T., Ivan, M. & Calin, G. A., Dec 1 2013, In : Cell Death and Differentiation. 20, 12, p. 1675-1687 13 p.

Research output: Contribution to journalArticle

64 Scopus citations

Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the alzheimer disease mouse model: In vivo and in vitro studies

Avrahami, L., Farfara, D., Shaham-Kol, M., Vassar, R., Frenkel, D. & Eldar-Finkelman, H., Jan 11 2013, In : Journal of Biological Chemistry. 288, 2, p. 1295-1306 12 p.

Research output: Contribution to journalArticle

136 Scopus citations

Involvement of androgens in ovarian health and disease

Lebbe, M. & Woodruff, T. K., Dec 2013, In : Molecular human reproduction. 19, 12, p. 828-837 10 p., gat065.

Research output: Contribution to journalReview article

69 Scopus citations

Isoform level expression profiles provide better cancer signatures than gene level expression profiles

Zhang, Z., Pal, S., Bi, Y., Tchou, J. & Davuluri, R. V., Apr 17 2013, In : Genome Medicine. 5, 4, 33.

Research output: Contribution to journalArticle

35 Scopus citations

Microarray analysis identifies COMP as the most differentially regulated transcript throughout in vitro follicle growth

Skory, R. M., Bernabé, B. P., Galdones, E., Broadbelt, L. J., Shea, L. D. & Woodruff, T. K., Feb 2013, In : Molecular reproduction and development. 80, 2, p. 132-144 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Naming vs knowing faces in primary progressive aphasia: A tale of 2 hemispheres

Gefen, T., Wieneke, C., Martersteck, A., Whitney, K., Weintraub, S., Mesulam, M. M. & Rogalski, E., Aug 13 2013, In : Neurology. 81, 7, p. 658-664 7 p.

Research output: Contribution to journalArticle

33 Scopus citations
120 Scopus citations

NPEBseq: Nonparametric empirical bayesian-based procedure for differential expression analysis of RNA-seq data

Bi, Y. & Davuluri, R. V., Aug 27 2013, In : BMC bioinformatics. 14, 1, 262.

Research output: Contribution to journalArticle

19 Scopus citations

Opportunities for genomic clinical decision support interventions

Overby, C. L., Kohane, I., Kannry, J. L., Williams, M. S., Starren, J. B., Bottinger, E., Gottesman, O., Denny, J. C., Weng, C., Tarczy-Hornoch, P. & Hripcsak, G., Oct 1 2013, In : Genetics in Medicine. 15, 10, p. 817-823 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Practical challenges in integrating genomic data into the electronic health record

Kho, A. N., Rasmussen, L. V., Connolly, J. J., Peissig, P. L., Starren, J., Hakonarson, H. & Hayes, M. G., Oct 2013, In : Genetics in Medicine. 15, 10, p. 772-778 7 p.

Research output: Contribution to journalReview article

44 Scopus citations

Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and alzheimer disease-like transgenic mouse models

Frost, J. L., Le, K. X., Cynis, H., Ekpo, E., Kleinschmidt, M., Palmour, R. M., Ervin, F. R., Snigdha, S., Cotman, C. W., Saido, T. C., Vassar, R. J., George-Hyslop, P. S., Ikezu, T., Schilling, S., Demuth, H. U. & Lemere, C. A., Aug 2013, In : American Journal of Pathology. 183, 2, p. 369-381 13 p.

Research output: Contribution to journalArticle

63 Scopus citations
18 Scopus citations

The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques

Kandalepas, P. C., Sadleir, K. R., Eimer, W. A., Zhao, J., Nicholson, D. A. & Vassar, R., Sep 2013, In : Acta Neuropathologica. 126, 3, p. 329-352 24 p.

Research output: Contribution to journalArticle

125 Scopus citations

Verbal and nonverbal memory in primary progressive aphasia: The Three Words-Three Shapes Test

Weintraub, S., Rogalski, E., Shaw, E., Sawlani, S., Rademaker, A., Wieneke, C. & Mesulam, M. M., Jan 1 2013, In : Behavioural Neurology. 26, 1-2, p. 67-76 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Words and objects at the tip of the left temporal lobe in primary progressive aphasia

Mesulam, M-M., Wieneke, C., Hurley, R., Rademaker, A., Thompson, C., Weintraub, S. & Rogalski, E., Jan 2013, In : Brain. 136, p. 601618

Research output: Contribution to journalArticle

110 Scopus citations
48 Scopus citations
2012

Age-associated alteration of oocyte-specific gene expression in polar bodies: Potential markers of oocyte competence

Jiao, Z. X., Xu, M. & Woodruff, T. K., Aug 2012, In : Fertility and Sterility. 98, 2, p. 480-486 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Age-related changes in parahippocampal white matter integrity: A diffusion tensor imaging study

Rogalski, E., Stebbins, G. T., Barnes, C. A., Murphy, C. M., Stoub, T. R., George, S., Ferrari, C., Shah, R. C. & deToledo-Morrell, L., Jul 1 2012, In : Neuropsychologia. 50, 8, p. 1759-1765 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Aging-associated B7-DC + B cells enhance anti-tumor immunity via Th1 and Th17 induction

Tomihara, K., Shin, T., Hurez, V. J., Yagita, H., Pardoll, D. M., Zhang, B., Curiel, T. J. & Shin, T., Feb 1 2012, In : Aging Cell. 11, 1, p. 128-138 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Alternative transcription and alternative splicing in cancer

Pal, S., Gupta, R. & Davuluri, R. V., Dec 2012, In : Pharmacology and Therapeutics. 136, 3, p. 283-294 12 p.

Research output: Contribution to journalReview article

75 Scopus citations

Anatomic, clinical, and neuropsychological correlates of spelling errors in primary progressive aphasia

Shim, H. S., Hurley, R. S., Rogalski, E. & Mesulam, M. M., Jul 2012, In : Neuropsychologia. 50, 8, p. 1929-1935 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Approach to the patient with dizziness and vertigo

Hain, T. C., Oct 22 2012, Practical Neurology: Fourth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 152-167 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection

Deng, Z., Wang, Z., Stong, N., Plasschaert, R., Moczan, A., Chen, H. S., Hu, S., Wikramasinghe, P., Davuluri, R. V., Bartolomei, M. S., Riethman, H. & Lieberman, P. M., Oct 31 2012, In : EMBO Journal. 31, 21, p. 4165-4178 14 p.

Research output: Contribution to journalArticle

91 Scopus citations

A Zinc-Dependent Mechanism Regulates Meiotic Progression in Mammalian Oocytes

Bernhardt, M. L., Kong, B. Y., Kim, A. M., O'Halloran, T. V. & Woodruff, T. K., Apr 1 2012, In : Biology of reproduction. 86, 4, 114.

Research output: Contribution to journalArticle

59 Scopus citations

Best Practices and pearls in interdisciplinary mentoring from building interdisciplinary research careers in women's health directors

Building Interdisciplinary Research Careers in Women’s Health Directors, Nov 1 2012, In : Journal of Women's Health. 21, 11, p. 1114-1127 14 p.

Research output: Contribution to journalArticle

9 Scopus citations
46 Scopus citations

Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia

Gefen, T., Gasho, K., Rademaker, A., Lalehzari, M., Weintraub, S., Rogalski, E., Wieneke, C., Bigio, E., Geula, C. & Mesulam, M. M., May 2012, In : Brain. 135, 5, p. 1554-1565 12 p.

Research output: Contribution to journalArticle

81 Scopus citations

Development of an optical character recognition pipeline for handwritten form fields from an electronic health record

Rasmussen, L. V., Peissig, P. L., McCarty, C. A. & Starren, J. B., Jun 1 2012, In : Journal of the American Medical Informatics Association. 19, E1, p. e90-e95

Research output: Contribution to journalArticle

17 Scopus citations

Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice

Perez, S. E., Nadeem, M., Sadleir, K. R., Matras, J., Kelley, C. M., Counts, S. E., Vassar, R. & Mufson, E. J., Oct 9 2012, In : International Journal of Physiology, Pathophysiology and Pharmacology. 4, 3, p. 115-127 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Embryonic fibroblasts enable the culture of primary ovarian follicles within alginate hydrogels

Tagler, D., Tu, T., Smith, R. M., Anderson, N. R., Tingen, C. M., Woodruff, T. K. & Shea, L. D., Jun 1 2012, In : Tissue Engineering - Part A. 18, 11-12, p. 1229-1238 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Estimation of gene expression at isoform level from mRNA-seq data by Bayesian hierarchical modeling

Bhattacharjee, M., Gupta, R. & Davuluri, R. V., 2012, In : Frontiers in Genetics. 3, NOV, Article 239.

Research output: Contribution to journalArticle

Identification and biology of β-secretase

Kandalepas, P. C. & Vassar, R., Jan 1 2012, In : Journal of neurochemistry. 120, SUPPL. 1, p. 55-61 7 p.

Research output: Contribution to journalReview article

69 Scopus citations

Identification of host-chromosome binding sites and candidate gene targets for Kaposi's sarcoma-associated herpesvirus LANA

Lu, F., Tsai, K., Chen, H. S., Wikramasinghe, P., Davuluri, R. V., Showe, L., Domsic, J., Marmorstein, R. & Lieberman, P. M., May 2012, In : Journal of virology. 86, 10, p. 5752-5762 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Importance of multi-modal approaches to effectively identify cataract cases from electronic health records

Peissig, P. L., Rasmussen, L. V., Berg, R. L., Linneman, J. G., McCarty, C. A., Waudby, C., Chen, L., Denny, J. C., Wilke, R. A., Pathak, J., Carrell, D., Kho, A. N. & Starren, J. B., Mar 1 2012, In : Journal of the American Medical Informatics Association. 19, 2, p. 225-234 10 p.

Research output: Contribution to journalArticle

70 Scopus citations

Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice

Hurez, V., Daniel, B. J., Sun, L., Liu, A. J., Ludwig, S. M., Kious, M. J., Thibodeaux, S. R., Pandeswara, S., Murthy, K., Livi, C. B., Wall, S., Brumlik, M. J., Shin, T., Zhang, B. & Curiel, T. J., Apr 15 2012, In : Cancer Research. 72, 8, p. 2089-2099 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Neural mechanisms of object naming and word comprehension in primary progressive aphasia

Hurley, R. S., Paller, K. A., Rogalski, E. J. & Marsel Mesulam, M., Apr 4 2012, In : Journal of Neuroscience. 32, 14, p. 4848-4855 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Proof of concept for the role of glycemic control in the early detection of infections in diabetics

Botsis, T., Lai, A. M., Hripcsak, G., Palmas, W., Starren, J. B. & Hartvigsen, G., Mar 1 2012, In : Health informatics journal. 18, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Quantitative classification of primary progressive aphasia at early and mild impairment stages

Mesulam, M. M., Wieneke, C., Thompson, C., Rogalski, E. & Weintraub, S., May 2012, In : Brain. 135, 5, p. 1537-1553 17 p.

Research output: Contribution to journalArticle

159 Scopus citations

RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion

Xiang, C., Baubet, V., Pal, S., Holderbaum, L., Tatard, V., Jiang, P., Davuluri, R. V. & Dahmane, N., Apr 1 2012, In : Cell Death and Differentiation. 19, 4, p. 692-702 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Semantic interference during object naming in agrammatic and logopenic primary progressive aphasia (PPA)

Thompson, C. K., Cho, S., Price, C., Wieneke, C., Bonakdarpour, B., Rogalski, E., Weintraub, S. & Mesulam, M. M., Mar 1 2012, In : Brain and Language. 120, 3, p. 237-250 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Sequencing and analysis of a South Asian-Indian personal genome

Gupta, R., Ratan, A., Rajesh, C., Chen, R., Kim, H. L., Burhans, R., Miller, W., Santhosh, S., Davuluri, R. V., Butte, A. J., Schuster, S. C., Seshagiri, S. & Thomas, G., Aug 31 2012, In : BMC Genomics. 13, 1, 440.

Research output: Contribution to journalArticle

19 Scopus citations
63 Scopus citations

The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type

Jendrzejewski, J., He, H., Radomska, H. S., Li, W., Tomsic, J., Liyanarachchi, S., Davuluri, R. V., Nagy, R. & De La Chapelle, A., May 29 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 22, p. 8646-8651 6 p.

Research output: Contribution to journalArticle

173 Scopus citations

The Possible Role of Resource Requirements and Academic Career-Choice Risk on Gender Differences in Publication Rate and Impact

Duch, J., Zeng, X. H. T., Sales-Pardo, M., Radicchi, F., Otis, S., Woodruff, T. K. & Nunes Amaral, L. A., Dec 12 2012, In : PloS one. 7, 12, e51332.

Research output: Contribution to journalArticle

99 Scopus citations

Zinc maintains prophase i arrest in mouse oocytes through regulation of the: Mos-mapk pathway

Kong, B. Y., Bernhardt, M. L., Kim, A. M., O'Halloran, T. V. & Woodruff, T. K., Jul 2012, In : Biology of reproduction. 87, 1, p. 11 1 p.

Research output: Contribution to journalArticle

39 Scopus citations

β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects

Hitt, B., Riordan, S. M., Kukreja, L., Eimer, W. A., Rajapaksha, T. W. & Vassar, R., Nov 9 2012, In : Journal of Biological Chemistry. 287, 46, p. 38408-38425 18 p.

Research output: Contribution to journalArticle

95 Scopus citations