Life Sciences Graduate Programs

Research Output

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A., Lee, S. E., Wojta, K., Ramos, E. M., Klein, E., Chen, J., Boxer, A. L., Gorno-Tempini, M. L., Geschwind, D. H., Schlotawa, L., Ogryzko, N. V., Bigio, E. H., Rogalski, E., Weintraub, S., Mesulam, M. M., Fleming, A., Coppola, G., Miller, B. L., Rubinsztein, D. C., Agosta, F. & 31 others, Alberici, A., Babacan-Yildiz, G., Bennett, D. A., Bilguvar, K., Borroni, B., Caglayan, A. O., Combarros, O., Comi, G., Cortés, E. P., Ferrer, I., Genç, Ş., Gunel, M., Gylys, K. H., Indakoetxea, B., Karageorgiou, C. E., Karydas, A., Kilic, U., De Munain, A. L., Magnani, G., Mahley, R. W., Boneschi, F. M., Martinez, J., Mazzeo, S., Moreno, F., Padovani, A., Papatriantafyllou, J., Rogaeva, E., Sanchez-Juan, P., Santangelo, R., Small, G. W. & Tauopathy Genetics Consortium, Apr 1 2017, In : Brain. 140, 4, p. 1128-1146 19 p.

Research output: Contribution to journalArticle

34 Scopus citations

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Rocchi, A., Yamamoto, S., Ting, T., Fan, Y., Sadleir, K., Wang, Y., Zhang, W., Huang, S., Levine, B., Vassar, R. & He, C., Aug 2017, In : PLoS genetics. 13, 8, e1006962.

Research output: Contribution to journalArticle

29 Scopus citations

Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer

Brena, R. M., Morrison, C., Liyanarachchi, S., Jarjoura, D., Davuluri, R. V., Otterson, G. A., Reisman, D., Glaros, S., Rush, L. J. & Plass, C., Mar 1 2007, In : PLoS medicine. 4, 3, p. 572-584 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Aberrant transforming growth factor β1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer

Chan, M. W. Y., Huang, Y. W., Hartman-Frey, C., Kuo, C. T., Deatherage, D., Qin, H., Cheng, A. S. L., Yan, P. S., Davuluri, R. V., Huang, T. H. M., Nephew, K. P. & Lin, H. J. L., Sep 2008, In : Neoplasia. 10, 9, p. 908-919 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

A better way to evaluate clinical ethics consultations? An ecological approach

Gordon, E. J., Feb 1 2007, In : American Journal of Bioethics. 7, 2, p. 26-29 4 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

A Call for Research on Individuals Who Opt out of Living Kidney Donation: Challenges and Opportunities

Thiessen, C., Kulkarni, S., Reese, P. P. & Gordon, E. J., Dec 1 2016, In : Transplantation. 100, 12, p. 2527-2532 6 p.

Research output: Contribution to journalReview article

7 Scopus citations

Accuracy and reliability of remote retinopathy of prematurity diagnosis

Chiang, M. F., Keenan, J. D., Starren, J., Du, Y. E., Schiff, W. M., Barile, G. R., Li, J., Johnson, R. A., Hess, D. J. & Flynn, J. T., Mar 1 2006, In : Archives of Ophthalmology. 124, 3, p. 322-327 6 p.

Research output: Contribution to journalReview article

94 Scopus citations

A cognitive framework for understanding barriers to the productive use of a diabetes home telemedicine system.

Kaufman, D. R., Starren, J., Patel, V. L., Morin, P. C., Hilliman, C., Pevzner, J., Weinstock, R. S., Goland, R. & Shea, S., 2003, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. p. 356-360 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

A cortical pathway to olfactory naming: Evidence from primary progressive aphasia

Olofsson, J. K., Rogalski, E., Harrison, T., Mesulam, M. M. & Gottfried, J. A., Apr 2013, In : Brain. 136, 4, p. 1245-1259 15 p.

Research output: Contribution to journalArticle

43 Scopus citations
5 Scopus citations

A culturally targeted website for hispanics/latinos about living kidney donation and transplantation: A randomized controlled trial of increased knowledge

Gordon, E. J., Feinglass, J., Carney, P., Vera, K., Olivero, M., Black, A., O'Connor, K., MacLean, J., Nichols, S., Sageshima, J., Preczewski, L. & Caicedo, J. C., Jan 1 2016, In : Transplantation. 100, 5, p. 1149-1160 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes

Baldus, C. D., Liyanarachchi, S., Mrózek, K., Auer, H., Tanner, S. M., Guimond, M., Ruppert, A. S., Mohamed, N., Davuluri, R. V., Caligiuri, M. A., Bloomfield, C. D. & De La Chapelle, A., Mar 16 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 11, p. 3915-3920 6 p.

Research output: Contribution to journalArticle

129 Scopus citations

ADAM10 prodomain mutations cause late-onset alzheimer's disease: Not just the latest FAD

Vassar, R., Oct 16 2013, In : Neuron. 80, 2, p. 250-253 4 p.

Research output: Contribution to journalShort survey

14 Scopus citations

ADAR1 forms a complex with dicer to promote MicroRNA processing and RNA-induced gene silencing

Ota, H., Sakurai, M., Gupta, R., Valente, L., Wulff, B. E., Ariyoshi, K., Iizasa, H., Davuluri, R. V. & Nishikura, K., Apr 25 2013, In : Cell. 153, 3, p. 575-589 15 p.

Research output: Contribution to journalArticle

163 Scopus citations

Adherence to Immunosuppression: A Prospective Diary Study

Gordon, E. J., Prohaska, T. R., Gallant, M. P. & Siminoff, L. A., Dec 1 2007, In : Transplantation Proceedings. 39, 10, p. 3081-3085 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Ad-hoc association of pre-determined ZigBee devices

Seeling, P. & Starren, J. B., Dec 31 2009, 2009 6th Annual International Conference on Mobile and Ubiquitous Systems: Networking and Services, MobiQuitous 2009. 5326384

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

A founding locus within the RET proto-oncogene may account for a large proportion of apparently sporadic Hirschsprung disease and a subset of cases of sporadic medullary thyroid carcinoma

Borrego, S., Wright, F. A., Fernández, R. M., Williams, N., López-Alonso, M., Davuluri, R., Antiñolo, G. & Eng, C., Jan 1 2003, In : American Journal of Human Genetics. 72, 1, p. 88-100 13 p.

Research output: Contribution to journalArticle

93 Scopus citations

A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and alzheimer's disease Aβ production

Buggia-Prévot, V., Fernandez, C. G., Udayar, V., Vetrivel, K. S., Elie, A., Roseman, J., Sasse, V. A., Lefkow, M., Meckler, X., Bhattacharyya, S., George, M., Kar, S., Bindokas, V. P., Parent, A. T., Rajendran, L., Band, H., Vassar, R. & Thinakaran, G., Dec 26 2013, In : Cell reports. 5, 6, p. 1552-1563 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases

Coulombe, P. A., Hutton, M. E., Vassar, R. & Fuchs, E., Jan 1 1991, In : Journal of Cell Biology. 115, 6, p. 1661-1674 14 p.

Research output: Contribution to journalArticle

149 Scopus citations

A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's β-secretase

Bennett, B. D., Denis, P., Haniu, M., Teplow, D. B., Kahn, S., Louis, J. C., Citron, M. & Vassar, R., Dec 1 2000, In : Journal of Biological Chemistry. 275, 48, p. 37712-37717 6 p.

Research output: Contribution to journalArticle

222 Scopus citations

Age-related changes in parahippocampal white matter integrity: A diffusion tensor imaging study

Rogalski, E., Stebbins, G. T., Barnes, C. A., Murphy, C. M., Stoub, T. R., George, S., Ferrari, C., Shah, R. C. & deToledo-Morrell, L., Jul 1 2012, In : Neuropsychologia. 50, 8, p. 1759-1765 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Aging-associated B7-DC + B cells enhance anti-tumor immunity via Th1 and Th17 induction

Tomihara, K., Shin, T., Hurez, V. J., Yagita, H., Pardoll, D. M., Zhang, B., Curiel, T. J. & Shin, T., Feb 1 2012, In : Aging Cell. 11, 1, p. 128-138 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

AGRIS: Arabidopsis Gene Regulatory Information Server, an information resource of Arabidopsis cis-regulatory elements and transcription factors

Davuluri, R. V., Sun, H., Palaniswamy, S. K., Matthews, N., Molina, C., Kurtz, M. & Grotewold, E., Jun 23 2003, In : BMC bioinformatics. 4, 25.

Research output: Contribution to journalArticle

279 Scopus citations

AGRIS and AtRegNet. A platform to link cis-regulatory elements and transcription factors into regulatory networks

Palaniswamy, S. K., James, S., Sun, H., Lamb, R. S., Davuluri, R. V. & Grotewold, E., Mar 1 2006, In : Plant Physiology. 140, 3, p. 818-829 12 p.

Research output: Contribution to journalArticle

179 Scopus citations

A Java speech implementation of the Mini Mental Status Exam.

Wang, S. S. & Starren, J., 1999, In : Proceedings / AMIA ... Annual Symposium. AMIA Symposium. p. 435-439 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Alternative transcription and alternative splicing in cancer

Pal, S., Gupta, R. & Davuluri, R. V., Dec 1 2012, In : Pharmacology and Therapeutics. 136, 3, p. 283-294 12 p.

Research output: Contribution to journalReview article

71 Scopus citations

Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development

Pal, S., Gupta, R., Kim, H., Wickramasinghe, P., Baubet, V., Showe, L. C., Dahmane, N. & Davuluri, R. V., Aug 1 2011, In : Genome research. 21, 8, p. 1260-1272 13 p.

Research output: Contribution to journalArticle

115 Scopus citations

Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia

Mesulam, M., Wicklund, A., Johnson, N., Rogalski, E., Léger, G. C., Rademaker, A., Weintraub, S. & Bigio, E. H., Jun 1 2008, In : Annals of neurology. 63, 6, p. 709-719 11 p.

Research output: Contribution to journalArticle

341 Scopus citations

Alzheimer disease Aβ production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts

Vetrivel, K. S., Meckler, X., Chen, Y., Nguyen, P. D., Seidah, N. G., Vassar, R., Wong, P. C., Fukata, M., Kounnas, M. Z. & Thinakaran, G., Feb 6 2009, In : Journal of Biological Chemistry. 284, 6, p. 3793-3803 11 p.

Research output: Contribution to journalArticle

106 Scopus citations

Alzheimer’s therapy: A BACE in the hand?

Vassar, R. & Ishiura, S., Aug 2011, In : Nature Medicine. 17, 8, 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

A microRNA component of the hypoxic response

Kulshreshtha, R., Davuluri, R. V., Calin, G. A. & Ivan, M., Apr 1 2008, In : Cell Death and Differentiation. 15, 4, p. 667-671 5 p.

Research output: Contribution to journalReview article

193 Scopus citations

A microRNA signature of hypoxia

Kulshreshtha, R., Ferracin, M., Wojcik, S. E., Garzon, R., Alder, H., Agosto-Perez, F. J., Davuluri, R., Liu, C. G., Croce, C. M., Negrini, M., Calin, G. A. & Ivan, M., Mar 1 2007, In : Molecular and cellular biology. 27, 5, p. 1859-1867 9 p.

Research output: Contribution to journalArticle

781 Scopus citations

A mixed-methods study of veterans affairs providers’ experiences communicating with patients about the affordable care act

Martinez, R. N., Gordon, E. J., Tully, S., Silva, A., Tarlov, E., French, D. D., Huo, Z., Smith, B. M., Gordon, H. S. & Stroupe, K. T., May 2017, In : Military medicine. 182, 5, p. e1715-e1723

Research output: Contribution to journalArticle

1 Scopus citations

A mixture model-based discriminate analysis for identifying ordered transcription factor binding site pairs in gene promoters directly regulated by estrogen receptor-α

Li, L., Cheng, A. S. L., Jin, V. X., Paik, H. H., Fan, M., Li, X., Zhang, W., Robarge, J., Balch, C., Davuluri, R. V., Kim, S., Huang, T. H. M. & Nephew, K. P., Sep 15 2006, In : Bioinformatics. 22, 18, p. 2210-2216 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Amyloid precursor protein processing in sterol regulatory element- binding protein site 2 protease-deficient Chinese hamster ovary cells

Ross, S. L., Martin, F., Simonet, L., Jacobsen, F., Deshpande, R., Vassar, R., Bennett, B., Luo, Y., Wooden, S., Hu, S., Citron, M. & Burgess, T. L., Jun 19 1998, In : Journal of Biological Chemistry. 273, 25, p. 15309-15312 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Amyloid-β42 alters apolipoprotein E solubility in brains of mice with five familial AD mutations

Youmans, K. L., Leung, S., Zhang, J., Maus, E., Baysac, K., Bu, G., Vassar, R., Yu, C. & LaDu, M. J., Mar 15 2011, In : Journal of Neuroscience Methods. 196, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

An ancillary genomics system to support the return of pharmacogenomic results

Rasmussen, L. V., Smith, M. E., Almaraz, F., Persell, S. D., Rasmussen-Torvik, L. J., Pacheco, J. A., Chisholm, R. L., Christensen, C., Herr, T. M., Wehbe, F. H. & Starren, J. B., Feb 19 2019, In : Journal of the American Medical Informatics Association. 26, 4, p. 306-310 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

An AscI boundary library for the studies of genetic and epigenetic alterations in CpG islands

Dai, Z., Weichenhan, D., Wu, Y. Z., Hall, J. L., Rush, L. J., Smith, L. T., Raval, A., Yu, L., Kroll, D., Muehlisch, J., Frühwald, M. C., De Jong, P., Catanese, J., Davuluri, R. V., Smiraglia, D. J. & Plass, C., Oct 1 2002, In : Genome research. 12, 10, p. 1591-1598 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Anatomic, clinical, and neuropsychological correlates of spelling errors in primary progressive aphasia

Shim, H. S., Hurley, R. S., Rogalski, E. & Mesulam, M. M., Jul 1 2012, In : Neuropsychologia. 50, 8, p. 1929-1935 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Anatomy of language impairments in primary progressive aphasia

Rogalski, E. J., Cobia, D., Harrison, T. M., Wieneke, C., Thompson, C. K., Weintraub, S. & Mesulam, M. M., Mar 2 2011, In : Journal of Neuroscience. 31, 9, p. 3344-3350 7 p.

Research output: Contribution to journalArticle

122 Scopus citations
1 Scopus citations

An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules

Qin, H., Chan, M. W. Y., Liyanarachchi, S., Balch, C., Potter, D., Souriraj, I. J., Cheng, A. S. L., Agosto-Perez, F. J., Nikonova, E. V., Yan, P. S., Lin, H. J., Nephew, K. P., Saltz, J. H., Showe, L. C., Huang, T. H. M. & Davuluri, R. V., Jul 17 2009, In : BMC systems biology. 3, 73.

Research output: Contribution to journalArticle

52 Scopus citations

Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data

Gupta, R., Wikramasinghe, P., Bhattacharyya, A., Perez, F. A., Pal, S. & Davuluri, R. V., Jan 18 2010, In : BMC bioinformatics. 11, SUPPLL.1, S65.

Research output: Contribution to journalArticle

21 Scopus citations

An object-oriented taxonomy of medical data presentations

Starren, J. & Johnson, S. B., Jan 1 2000, In : Journal of the American Medical Informatics Association. 7, 1, p. 1-20 20 p.

Research output: Contribution to journalReview article

30 Scopus citations

A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies

Yu, L., Liu, C., Bennett, K., Wu, Y. Z., Dai, Z., Vandeusen, J., Opavsky, R., Raval, A., Trikha, P., Rodriguez, B., Becknell, B., Mao, C., Lee, S., Davuluri, R. V., Leone, G., Van Den Veyver, I. B., Caligiuri, M. A. & Plass, C., Oct 1 2004, In : Genomics. 84, 4, p. 647-660 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

A novel frontal pathway underlies verbal fluency in primary progressive aphasia

Catani, M., Mesulam, M. M., Jakobsen, E., Malik, F., Martersteck, A., Wieneke, C., Thompson, C. K., Thiebaut De Schotten, M., Dell'Acqua, F., Weintraub, S. & Rogalski, E., Aug 2013, In : Brain. 136, 8, p. 2619-2628 10 p.

Research output: Contribution to journalArticle

203 Scopus citations

Anticipating and addressing the unintended consequences of health IT and policy: A report from the AMIA 2009 Health Policy Meeting

Bloomrosen, M., Starren, J., Lorenzi, N. M., Ash, J. S., Patel, V. L. & Shortliffe, E. H., Jan 1 2011, In : Journal of the American Medical Informatics Association. 18, 1, p. 82-90 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b+Gr-1+ cells

Tomihara, K., Guo, M., Shin, T., Sun, X., Ludwig, S. M., Brumlik, M. J., Zhang, B., Curiel, T. J. & Shin, T., Jun 1 2010, In : Journal of Immunology. 184, 11, p. 6151-6160 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Anti-inflammatory drug therapy alters β-amyloid processing and deposition in an animal model of Alzheimer's disease

Yan, Q., Zhang, J., Liu, H., Babu-Khan, S., Vassar, R., Biere, A. L., Citron, M. & Landreth, G., Aug 20 2003, In : Journal of Neuroscience. 23, 20, p. 7504-7509 6 p.

Research output: Contribution to journalArticle

422 Scopus citations