Life Sciences Graduate Programs

Research Output

Article

Architecture for remote training of home telemedicine patients.

Lai, A. M., Starren, J. B., Shea, S. & IDEATel Consortium, C., Jan 1 2005, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

A receptor guanylyl cyclase expressed specifically in olfactory sensory neurons

Fulle, H. J., Vassar, R., Foster, D. C., Yang, R. B., Axel, R. & Garbers, D. L., Apr 11 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 8, p. 3571-3575 5 p.

Research output: Contribution to journalArticle

216 Scopus citations

Are there susceptibility factors for primary progressive aphasia?

Rogalski, E., Weintraub, S. & Mesulam, M. M., Nov 1 2013, In : Brain and Language. 127, 2, p. 135-138 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection

Deng, Z., Wang, Z., Stong, N., Plasschaert, R., Moczan, A., Chen, H. S., Hu, S., Wikramasinghe, P., Davuluri, R. V., Bartolomei, M. S., Riethman, H. & Lieberman, P. M., Oct 31 2012, In : EMBO Journal. 31, 21, p. 4165-4178 14 p.

Research output: Contribution to journalArticle

90 Scopus citations

Assessment of image-based technology: impact of referral cutoff on accuracy and reliability of remote retinopathy of prematurity diagnosis.

Chiang, M. F., Keenan, J. D., Du, Y. E., Schiff, W., Barile, G., Li, J., Hess, D. J., Johnson, R. A., Flynn, J. T. & Starren, J., Jan 1 2005, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. p. 126-130 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Association between the prevalence of learning disabilities and primary progressive aphasia

Rogalski, E. J., Rademaker, A., Wieneke, C., Bigio, E. H., Weintraub, S. & Mesulam, M. M., Dec 1 2014, In : JAMA Neurology. 71, 12, p. 1576-1577 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of b-cell chronic lymphocytic leukemia

Fabbri, M., Bottoni, A., Shimizu, M., Spizzo, R., Nicoloso, M. S., Rossi, S., Barbarotto, E., Cimmino, A., Adair, B., Wojcik, S. E., Valeri, N., Calore, F., Sampath, D., Fanini, F., Vannini, I., Musuraca, G., Dell'Aquila, M., Alder, H., Davuluri, R. V., Rassenti, L. Z. & 9 others, Negrini, M., Nakamura, T., Amadori, D., Kay, N. E., Rai, K. R., Keating, M. J., Kipps, T. J., Calin, G. A. & Croce, C. M., Jan 5 2011, In : JAMA - Journal of the American Medical Association. 305, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

226 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

196 Scopus citations

Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection

Iram, T., Trudler, D., Kain, D., Kanner, S., Galron, R., Vassar, R., Barzilai, A., Blinder, P., Fishelson, Z. & Frenkel, D., Dec 1 2016, In : Neurobiology of Disease. 96, p. 84-94 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia

Mesulam, M. M., Weintraub, S., Rogalski, E. J., Wieneke, C., Geula, C. & Bigio, E. H., Apr 2014, In : Brain. 137, 4, p. 1176-1192 17 p.

Research output: Contribution to journalArticle

157 Scopus citations

Asymmetry of cortical decline in subtypes of primary progressive aphasia

Rogalski, E., Cobia, D., Martersteck, A., Rademaker, A., Wieneke, C., Weintraub, S. & Mesulam, M. M., Sep 1 2014, In : Neurology. 83, 13, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project

Overby, C. L., Rasmussen, L. V., Hartzler, A., Connolly, J. J., Peterson, J. F., Hedberg, R. M. E., Freimuth, R. R., Shirts, B. H., Denny, J. C., Larson, E. B., Chute, C. G., Jarvik, G. P., Ralston, J. D., Shuldiner, A. R., Starren, J. B., Kullo, I. J., Tarczy-Hornoch, P. & Williams, M. S., Jan 1 2014, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2014, p. 944-953 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
1 Scopus citations

Automating Content Extraction of HTML documents

Gupta, S., Kaiser, G. E., Grimm, P., Chiang, M. F. & Starren, J., Jun 1 2005, In : World Wide Web. 8, 2, p. 179-224 46 p.

Research output: Contribution to journalArticle

65 Scopus citations

Autonomy gone awry: A cross-cultural study of parents' experiences in neonatal intensive care units

Orfali, K. & Gordon, E. J., Nov 10 2004, In : Theoretical Medicine and Bioethics. 25, 4, p. 329-365 37 p.

Research output: Contribution to journalArticle

63 Scopus citations
4 Scopus citations

A website intervention to increase knowledge about living kidney donation and transplantation among hispanic/latino dialysis patients

Gordon, E. J., Feinglass, J., Carney, P., Vera, K., Olivero, M., Black, A., O'Connor, K. G., Baumgart, J. M. L. & Caicedo, J. C., Jan 1 2016, In : Progress in Transplantation. 26, 1, p. 82-91 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Axonal BACE1 dynamics and targeting in hippocampal neurons: A role for Rab11 GTPase

Buggia-Prévot, V., Fernandez, C. G., Riordan, S., Vetrivel, K. S., Roseman, J., Waters, J., Bindokas, V. P., Vassar, R. & Thinakaran, G., Jan 4 2014, In : Molecular neurodegeneration. 9, 1, 1.

Research output: Contribution to journalArticle

52 Scopus citations

Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level

Sadleir, K. R., Eimer, W. A., Cole, S. L. & Vassar, R., Jan 1 2015, In : Molecular neurodegeneration. 10, 1, 1.

Research output: Contribution to journalArticle

43 Scopus citations

B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses

Lin, P. Y., Sun, L., Thibodeaux, S. R., Ludwig, S. M., Vadlamudi, R. K., Hurez, V. J., Bahar, R., Kious, M. J., Livi, C. B., Wall, S. R., Chen, L., Zhang, B., Shin, T. & Curiel, T. J., Sep 1 2010, In : Journal of Immunology. 185, 5, p. 2747-2753 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

Hitt, B. D., Jaramillo, T. C., Chetkovich, D. M. & Vassar, R., Aug 26 2010, In : Molecular neurodegeneration. 5, 1, 31.

Research output: Contribution to journalArticle

68 Scopus citations

BACE1 (β-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time

Luo, Y., Bolon, B., Damore, M. A., Fitzpatrick, D., Liu, H., Zhang, J., Yan, Q., Vassar, R. & Citron, M., Jan 1 2003, In : Neurobiology of Disease. 14, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

142 Scopus citations

BACE1 Deficiency Rescues Memory Deficits and Cholinergic Dysfunction in a Mouse Model of Alzheimer's Disease

Ohno, M., Sametsky, E. A., Younkin, L. H., Oakley, H., Younkin, S. G., Citron, M., Vassar, R. & Disterhoft, J. F., Jan 8 2004, In : Neuron. 41, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

429 Scopus citations

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

Ohno, M., Cole, S. L., Yasvoina, M., Zhao, J., Citron, M., Berry, R., Disterhoft, J. F. & Vassar, R., Apr 1 2007, In : Neurobiology of Disease. 26, 1, p. 134-145 12 p.

Research output: Contribution to journalArticle

205 Scopus citations

BACE1 mediates HIV-associated and excitotoxic neuronal damage through an APP-dependent mechanism

Stern, A. L., Ghura, S., Gannon, P. J., Akay-Espinoza, C., Phan, J. M., Yee, A. C., Vassar, R., Gelman, B. B., Kolson, D. L. & Jordan-Sciutto, K. L., May 2 2018, In : Journal of Neuroscience. 38, 18, p. 4288-4300 13 p.

Research output: Contribution to journalArticle

14 Scopus citations
38 Scopus citations

Beta Secretase Genes

Citron, M., Vassar, R. & Bennett, BD., Sep 1 2009, In : United States Patent 7,582,465 B2.

Research output: Contribution to journalArticle

Beta Secretase Polypeptides

Citron, M., Vassar, RJ. & Bennett, BD., Aug 25 2009, In : United States Patent 7,579,180 B2.

Research output: Contribution to journalArticle

Bilateral vestibular loss

Hain, T. C., Cherchi, M. & Yacovino, D. A., Oct 1 2013, In : Seminars in Neurology. 33, 3, p. 195-203 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Breaking down the barriers to computerizing your practice.

Starren, J. & Clayton, P., May 1994, In : The Internist. 35, 5, p. 8-10, 15

Research output: Contribution to journalArticle

Breaking the translational barriers: The value of integrating biomedical informatics and translational research

Payne, P. R. O., Johnson, S. B., Starren, J. B., Tilson, H. H. & Dowdy, D., May 2005, In : Journal of Investigative Medicine. 53, 4, p. 192-200 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation

Calvert, A. E., Chalastanis, A., Wu, Y., Hurley, L. A., Kouri, F., Bi, Y., Kachman, M., May, J. L., Bartom, E. T., Hua, Y., Mishra, R. K., Schiltz, G. E., Dubrovskyi, O., Mazar, A. P., Peter, M. E., Zheng, H., James, C. D., Burant, C. F., Chandel, N., Davuluri, R. V. & 2 others, Horbinski, C. M. & Stegh, A. H., May 30 2017, In : Cell reports. 19, 9, p. 1858-1873 16 p.

Research output: Contribution to journalArticle

43 Scopus citations

Cancer classification and pathway discovery using non-negative matrix factorization

Zeng, Z., Vo, A. H., Mao, C., Clare, S. E., Khan, S. A. & Luo, Y., Aug 2019, In : Journal of Biomedical Informatics. 96, 103247.

Research output: Contribution to journalArticle

2 Scopus citations

Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

Hong, H. S., Maezawa, I., Budamagunta, M., Rana, S., Shi, A., Vassar, R., Liu, R., Lam, K. S., Cheng, R. H., Hua, D. H., Voss, J. C. & Jin, L. W., Oct 1 2010, In : Neurobiology of Aging. 31, 10, p. 1690-1699 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

CART classification of human 5' UTR sequences

Davuluri, R. V., Suzuki, Y., Sugano, S. & Zhang, M. Q., Dec 21 2000, In : Genome research. 10, 11, p. 1807-1816 10 p.

Research output: Contribution to journalArticle

125 Scopus citations

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

Ling, H., Spizzo, R., Atlasi, Y., Nicoloso, M., Shimizu, M., Redis, R. S., Nishida, N., Gafà, R., Song, J., Guo, Z., Ivan, C., Barbarotto, E., De Vries, I., Zhang, X., Ferracin, M., Churchman, M., Van Galen, J. F., Beverloo, B. H., Shariati, M., Haderk, F. & 33 others, Estecio, M. R., Garcia-Manero, G., Patijn, G. A., Gotley, D. C., Bhardwaj, V., Shureiqi, I., Sen, S., Multani, A. S., Welsh, J., Yamamoto, K., Taniguchi, I., Song, M. A., Gallinger, S., Casey, G., Thibodeau, S. N., Le Marchand, L., Tiirikainen, M., Mani, S. A., Zhang, W., Davuluri, R. V., Mimori, K., Mori, M., Sieuwerts, A. M., Martens, J. W. M., Tomlinson, I., Negrini, M., Berindan-Neagoe, I., Foekens, J. A., Hamilton, S. R., Lanza, G., Kopetz, S., Fodde, R. & Calin, G. A., Sep 2013, In : Genome research. 23, 9, p. 1446-1461 16 p.

Research output: Contribution to journalArticle

368 Scopus citations

CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

Wang, L., Fan, J., Thompson, L. F., Zhang, Y., Shin, T., Curiel, T. J. & Zhang, B., Jun 1 2011, In : Journal of Clinical Investigation. 121, 6, p. 2371-2382 12 p.

Research output: Contribution to journalArticle

148 Scopus citations

CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumor-induced immune suppression

Jin, D., Fan, J., Wang, L., Thompson, L. F., Liu, A., Daniel, B. J., Shin, T., Curiel, T. J. & Zhang, B., Mar 15 2010, In : Cancer Research. 70, 6, p. 2245-2255 11 p.

Research output: Contribution to journalArticle

233 Scopus citations
46 Scopus citations

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia

Oboudiyat, C., Gefen, T., Varelas, E., Weintraub, S., Rogalski, E., Bigio, E. H. & Mesulam, M. M., May 2017, In : Alzheimer's and Dementia. 13, 5, p. 598-601 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Changes in gene expression associated with loss of function of the NSDHL sterol dehydrogenase in mouse embryonic fibroblasts

Cunningham, D., Swartzlander, D., Liyanarachchi, S., Davuluri, R. V. & Herman, G. E., Dec 1 2005, In : Journal of lipid research. 46, 6, p. 1150-1162 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Changes in parahippocampal white matter integrity in amnestic mild cognitive impairment: A diffusion tensor imaging study

Rogalski, E. J., Murphy, C. M., Detoledo-Morrell, L., Shah, R. C., Moseley, M. E., Bammer, R. & Stebbins, G. T., Jan 1 2009, In : Behavioural Neurology. 21, 1-2, p. 51-61 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Characteristics of vestibular corrective saccades in patients with slow visual saccades, vestibular disorders and controls: A descriptive analysis

Yacovino, D. A., Martin, L. A., Akly, M. P. & Hain, T. C., May 2018, In : PloS one. 13, 5, e0197079.

Research output: Contribution to journalArticle

6 Scopus citations

Characterization of Alzheimer's β-secretase protein BACE: A pepsin family member with unusual properties

Haniu, M., Denis, P., Young, Y., Mendiaz, E. A., Fuller, J., Hui, J. O., Bennett, B. D., Kahn, S., Ross, S., Burgess, T., Katta, V., Rogers, G., Vassar, R. & Citron, M., Jul 14 2000, In : Journal of Biological Chemistry. 275, 28, p. 21099-21106 8 p.

Research output: Contribution to journalArticle

190 Scopus citations

Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors

Malchenko, S., Sredni, S. T., Boyineni, J., Bi, Y., Margaryan, N. V., Guda, M. R., Kostenko, Y., Tomita, T., Davuluri, R. V., Velpula, K., Hendrix, M. J. C. & Soares, M. B., Jan 1 2018, In : Oncotarget. 9, 17, p. 13733-13747 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Chemopreventive effects of heat-processed Panax quinquefolius root on human breast cancer cells

Wang, C. Z., Aung, H. H., Zhang, B., Sun, S., Li, X. L., He, H., Xie, J. T., He, T. C., Du, W. & Yuan, C. S., Sep 1 2008, In : Anticancer research. 28, 5 A, p. 2545-2551 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells

Wang, C. Z., Xie, J. T., Zhang, B., Ni, M., Fishbein, A., Aung, H. H., Mehendale, S. R., Du, W., He, T. C. & Yuan, C. S., Nov 1 2007, In : International journal of oncology. 31, 5, p. 1149-1156 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Children's contributions to designing a communication tool for children with cancer.

Ruland, C. M., Slaughter, L., Starren, J., Vatne, T. M. & Moe, E. Y., Nov 8 2007, In : Medinfo. MEDINFO. 12, Pt 2, p. 977-982 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B

Xu, D., Fu, J., Jin, L., Zhang, H., Zhou, C., Zou, Z., Zhao, J. M., Zhang, B., Shi, M., Ding, X., Tang, Z., Fu, Y. X. & Wang, F. S., Jul 1 2006, In : Journal of Immunology. 177, 1, p. 739-747 9 p.

Research output: Contribution to journalArticle

347 Scopus citations
9 Scopus citations