Life Sciences Graduate Programs

Research Output

Review article

BACE1: The β-secreiase enzyme in Alzheimer's disease

Vassar, R., Apr 1 2004, In : Journal of Molecular Neuroscience. 23, 1-2, p. 105-113 9 p.

Research output: Contribution to journalReview article

242 Scopus citations

BACE1 inhibitor drugs in clinical trials for Alzheimer's disease

Vassar, R., Dec 24 2014, In : Alzheimer's Research and Therapy. 6, 9

Research output: Contribution to journalReview article

210 Scopus citations

BACE1 structure and function in health and Alzheimer's disease

Cole, S. L. & Vassar, R., Apr 1 2008, In : Current Alzheimer Research. 5, 2, p. 100-120 21 p.

Research output: Contribution to journalReview article

78 Scopus citations

beta-Secretase, APP and Abeta in Alzheimer's disease.

Vassar, R., 2005, In : Sub-cellular biochemistry. 38, p. 79-103 25 p.

Research output: Contribution to journalReview article

58 Scopus citations

Big Data and Data Science in Critical Care

Sanchez-Pinto, L. N., Luo, Y. & Churpek, M. M., Nov 2018, In : CHEST. 154, 5, p. 1239-1248 10 p.

Research output: Contribution to journalReview article

35 Scopus citations

Bilateral vestibular weakness

Hain, T. C., Cherchi, M. & Yacovino, D. A., May 31 2018, In : Frontiers in Neurology. 9, MAY, 344.

Research output: Contribution to journalReview article

3 Scopus citations

CD73: A novel target for cancer immunotherapy

Zhang, B., Aug 15 2010, In : Cancer Research. 70, 16, p. 6407-6411 5 p.

Research output: Contribution to journalReview article

127 Scopus citations

Cervicogenic causes of vertigo

Hain, T. C., Feb 13 2015, In : Current Opinion in Neurology. 28, 1, p. 69-73 5 p.

Research output: Contribution to journalReview article

38 Scopus citations

Children, research, and guinea pigs: Reflections on a metaphor

Gordon, E. J., Yamokoski, A. H. & Kodish, E., Sep 1 2006, In : IRB Ethics and Human Research. 28, 5, p. 12-19 8 p.

Research output: Contribution to journalReview article

8 Scopus citations

Conceptual knowledge acquisition in biomedicine: A methodological review

Payne, P. R. O., Mendonça, E. A., Johnson, S. B. & Starren, J. B., Oct 1 2007, In : Journal of Biomedical Informatics. 40, 5, p. 582-602 21 p.

Research output: Contribution to journalReview article

44 Scopus citations

Development of a Donor-Centered Approach to Risk Assessment: Rebalancing Nonmaleficence and Autonomy

Thiessen, C., Gordon, E. J., Reese, P. P. & Kulkarni, S., Sep 1 2015, In : American Journal of Transplantation. 15, 9, p. 2314-2323 10 p.

Research output: Contribution to journalReview article

20 Scopus citations

Function, therapeutic potential and cell biology of BACE proteases: Current status and future prospects

Vassar, R., Kuhn, P. H., Haass, C., Kennedy, M. E., Rajendran, L., Wong, P. C. & Lichtenthaler, S. F., Jul 2014, In : Journal of neurochemistry. 130, 1, p. 4-28 25 p.

Research output: Contribution to journalReview article

213 Scopus citations

Identification and biology of β-secretase

Kandalepas, P. C. & Vassar, R., Jan 1 2012, In : Journal of neurochemistry. 120, SUPPL. 1, p. 55-61 7 p.

Research output: Contribution to journalReview article

69 Scopus citations

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease

Yan, R., Fan, Q., Zhou, J. & Vassar, R., Jun 1 2016, In : Neuroscience and Biobehavioral Reviews. 65, p. 326-340 15 p.

Research output: Contribution to journalReview article

35 Scopus citations

Isoprenoids and Alzheimer's disease: A complex relationship

Cole, S. L. & Vassar, R., May 1 2006, In : Neurobiology of Disease. 22, 2, p. 209-222 14 p.

Research output: Contribution to journalReview article

61 Scopus citations

Linking vascular disorders and Alzheimer's disease: Potential involvement of BACE1

Cole, S. L. & Vassar, R., Oct 1 2009, In : Neurobiology of Aging. 30, 10, p. 1535-1544 10 p.

Research output: Contribution to journalReview article

30 Scopus citations

MicroRNAs, ultraconserved genes and colorectal cancers

Rossi, S., Kopetz, S., Davuluri, R., Hamilton, S. R. & Calin, G. A., Aug 1 2010, In : International Journal of Biochemistry and Cell Biology. 42, 8, p. 1291-1297 7 p.

Research output: Contribution to journalReview article

43 Scopus citations

Molecular neurodegeneration: Basic biology and disease pathways

Vassar, R. & Zheng, H., Sep 23 2014, In : Molecular neurodegeneration. 9, 1, 34.

Research output: Contribution to journalReview article

2 Scopus citations

Natural Language Processing for EHR-Based Pharmacovigilance: A Structured Review

Luo, Y., Thompson, W. K., Herr, T. M., Zeng, Z., Berendsen, M. A., Jonnalagadda, S. R., Carson, M. B. & Starren, J. B., Nov 1 2017, In : Drug Safety. 40, 11, p. 1075-1089 15 p.

Research output: Contribution to journalReview article

38 Scopus citations

Organizing a series of education and support conferences for caregivers of individuals with frontotemporal dementia and primary progressive aphasia

Banks, S., Rogalski, E., Medina, J., Skoglund, A. & Morhardt, D., Oct 1 2006, In : Alzheimer's Care Quarterly. 7, 4, p. 243-250 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

Practical challenges in integrating genomic data into the electronic health record

Kho, A. N., Rasmussen, L. V., Connolly, J. J., Peissig, P. L., Starren, J., Hakonarson, H. & Hayes, M. G., Oct 1 2013, In : Genetics in Medicine. 15, 10, p. 772-778 7 p.

Research output: Contribution to journalReview article

43 Scopus citations

Primary progressive aphasia and the evolving neurology of the language network

Mesulam, M. M., Rogalski, E. J., Wieneke, C., Hurley, R. S., Geula, C., Bigio, E. H., Thompson, C. K. & Weintraub, S., Jan 1 2014, In : Nature Reviews Neurology. 10, 10, p. 554-569 16 p.

Research output: Contribution to journalReview article

109 Scopus citations

Residents' access to ethics consultations: Knowledge, use, and perceptions

Gacki-Smith, J. & Gordon, E. J., Feb 2005, In : Academic Medicine. 80, 2, p. 168-175 8 p.

Research output: Contribution to journalReview article

22 Scopus citations

Synergies and Distinctions between Computational Disciplines in Biomedical Research: Perspective from the Clinical and Translational Science Award Programs

Bernstam, E. V., Hersh, W. R., Johnson, S. B., Chute, C. G., Nguyen, H., Sim, I., Nahm, M., Weiner, M. G., Miller, P., DiLaura, R. P., Overcash, M., Lehmann, H. P., Eichmann, D., Athey, B. D., Scheuermann, R. H., Anderson, N., Starren, J., Harris, P. A., Smith, J. W., Barbour, E. & 4 others, Silverstein, J. C., Krusch, D. A., Nagarajan, R. & Becich, M. J., Jul 2009, In : Academic Medicine. 84, 7, p. 964-970 7 p.

Research output: Contribution to journalReview article

25 Scopus citations

Targeting the stroma by T cells to limit tumor growth

Zhang, B., Dec 1 2008, In : Cancer Research. 68, 23, p. 9570-9573 4 p.

Research output: Contribution to journalReview article

15 Scopus citations

Targeting the β secretase BACE1 for Alzheimer's disease therapy

Yan, R. & Vassar, R., Mar 1 2014, In : The Lancet Neurology. 13, 3, p. 319-329 11 p.

Research output: Contribution to journalReview article

349 Scopus citations

Telemedicine for Retinopathy of Prematurity Diagnosis: Evaluation and Challenges

Richter, G. M., Williams, S. L., Starren, J., Flynn, J. T. & Chiang, M. F., Nov 1 2009, In : Survey of Ophthalmology. 54, 6, p. 671-685 15 p.

Research output: Contribution to journalReview article

71 Scopus citations

The basic biology of BACE1: A key therapeutic target for Alzheimer's disease

Cole, S. L. & Vassar, R., Dec 1 2007, In : Current Genomics. 8, 8, p. 509-530 22 p.

Research output: Contribution to journalReview article

51 Scopus citations

The CARE Pathway Model for Dementia: Psychosocial and Rehabilitative Strategies for Care in Young-Onset Dementias

Morhardt, D., Weintraub, S., Khayum, B., Robinson, J., Medina, J., O'Hara, M., Mesulam, M. & Rogalski, E. J., Jun 1 2015, In : Psychiatric Clinics of North America. 38, 2, p. 333-352 20 p.

Research output: Contribution to journalReview article

10 Scopus citations

The courage to stand up: The cultural politics of nurses' access to ethics consultation

Gordon, E. J. & Hamric, A. B., Sep 1 2006, In : Journal of Clinical Ethics. 17, 3, p. 231-254 24 p.

Research output: Contribution to journalReview article

24 Scopus citations

The economics and ethics of kidney transplantation: Perspectives in 2006

Kim, S. J., Gordon, E. J. & Powe, N. R., Nov 1 2006, In : Current opinion in nephrology and hypertension. 15, 6, p. 593-598 6 p.

Research output: Contribution to journalReview article

3 Scopus citations

The functional consequences of alternative promoter use in mammalian genomes

Davuluri, R. V., Suzuki, Y., Sugano, S., Plass, C. & Huang, T. H. M., Apr 1 2008, In : Trends in Genetics. 24, 4, p. 167-177 11 p.

Research output: Contribution to journalReview article

216 Scopus citations

The role of nurses in installing telehealth technology in the home

Starren, J., Tsai, C., Bakken, S., Aidala, A., Morin, P. C., Hilliman, C., Weinstock, R. S., Goland, R., Teresi, J. & Shea, S., Jan 1 2005, In : CIN - Computers Informatics Nursing. 23, 4, p. 181-189 9 p.

Research output: Contribution to journalReview article

19 Scopus citations

The -secretase enzyme BACE1 as a therapeutic target for Alzheimer's disease

Vassar, R. & Kandalepas, P. C., May 6 2011, In : Alzheimer's Research and Therapy. 3, 3, 20.

Research output: Contribution to journalReview article

77 Scopus citations

The secretases: Enzymes with therapeutic potential in Alzheimer disease

De Strooper, B., Vassar, R. & Golde, T., Feb 1 2010, In : Nature Reviews Neurology. 6, 2, p. 99-107 9 p.

Research output: Contribution to journalReview article

508 Scopus citations

Validation of a decision regret scale

Brehaut, J. C., O'Connor, A. M., Wood, T. J., Hack, T. F., Siminoff, L., Gordon, E. & Feldman-Stewart, D., Jul 1 2003, In : Medical Decision Making. 23, 4, p. 281-292 12 p.

Research output: Contribution to journalReview article

483 Scopus citations

What “race” cannot tell us about access to kidney transplantation

Gordon, E. J., Jan 1 2002, In : Cambridge Quarterly of Healthcare Ethics. 11, 2, p. 134-141 8 p.

Research output: Contribution to journalReview article

10 Scopus citations
Short survey

ADAM10 prodomain mutations cause late-onset alzheimer's disease: Not just the latest FAD

Vassar, R., Oct 16 2013, In : Neuron. 80, 2, p. 250-253 4 p.

Research output: Contribution to journalShort survey

14 Scopus citations

Caspase-3 Cleavage of GGA3 Stabilizes BACE: Implications for Alzheimer's Disease

Vassar, R., Jun 7 2007, In : Neuron. 54, 5, p. 671-673 3 p.

Research output: Contribution to journalShort survey

20 Scopus citations

Crossing the omic chasm: A time for omic ancillary systems

Starren, J. B., Williams, M. S. & Bottinger, E. P., Mar 27 2013, In : JAMA - Journal of the American Medical Association. 309, 12, p. 1237-1238 2 p.

Research output: Contribution to journalShort survey

51 Scopus citations

Patient participation in electronic medical records

Tsai, C. C. & Starren, J., Apr 4 2001, In : Journal of the American Medical Association. 285, 13, 1 p.

Research output: Contribution to journalShort survey

18 Scopus citations
84 Scopus citations

Seeds of Destruction: New Mechanistic Insights into the Role of Apolipoprotein E4 in Alzheimer's Disease

Vassar, R., Dec 6 2017, In : Neuron. 96, 5, p. 953-955 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

The role of amyloid precursor protein processing by BACE1, the β-secretase, in Alzheimer disease pathophysiology

Cole, S. L. & Vassar, R., Oct 31 2008, In : Journal of Biological Chemistry. 283, 44, p. 29621-29625 5 p.

Research output: Contribution to journalShort survey

150 Scopus citations