Life Sciences Graduate Programs

Research Output

Article

Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease

Kaczorowski, C. C., Sametsky, E., Shah, S., Vassar, R. & Disterhoft, J. F., Aug 1 2011, In : Neurobiology of Aging. 32, 8, p. 1452-1465 14 p.

Research output: Contribution to journalArticle

53 Scopus citations

Medicare payments, healthcare service use, and telemedicine implementation costs in a randomized trial comparing telemedicine case management with usual care in medically underserved participants with diabetes mellitus (IDEATel)

Palmas, W., Shea, S., Starren, J., Teresi, J. A., Ganz, M. L., Burton, T. M., Pashos, C. L., Blustein, J., Field, L., Morin, P. C., Izquierdo, R. E., Silver, S., Eimicke, J. P., Lantigua, R. A. & Weinstock, R. S., Mar 1 2010, In : Journal of the American Medical Informatics Association. 17, 2, p. 196-202 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

Ng, M. C. Y., Shriner, D., Chen, B. H., Li, J., Chen, W. M., Guo, X., Liu, J., Bielinski, S. J., Yanek, L. R., Nalls, M. A., Comeau, M. E., Rasmussen-Torvik, L. J., Jensen, R. A., Evans, D. S., Sun, Y. V., An, P., Patel, S. R., Lu, Y., Long, J., Armstrong, L. L. & 32 others, Wagenknecht, L., Yang, L., Snively, B. M., Palmer, N. D., Mudgal, P., Langefeld, C. D., Keene, K. L., Freedman, B. I., Mychaleckyj, J. C., Nayak, U., Raffel, L. J., Goodarzi, M. O., Chen, Y. D. I., Taylor, H. A., Correa, A., Sims, M., Couper, D., Pankow, J. S., Boerwinkle, E., Adeyemo, A., Doumatey, A., Hayes, M. G., Starren, J., Chisholm, R. L., Greenland, P., Kho, A. N., Lowe, W. L., Smith, M. E., Thompson, W. K., Cornelis, M., The MAGIC investigators & The GIANT consortium, Aug 7 2014, In : PLoS genetics. 10, 8, e1004517.

Research output: Contribution to journalArticle

111 Scopus citations

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

Wang, G., Biswas, AK., Ma, W., Kandpal, M., Coker, C., Grandgenett, PM., Hollingsworth, MA., Jain, R., Tanji, K., Lomicronpez-Pintado, S., Borczuk, A., Hebert, D., Jenkitkasemwong, S., Hojyo, S., Davuluri, RV., Knutson, MD., Fukada, T. & Acharyya, S., Jun 8 2018, In : Nature Medicine. 24, 6, p. 770-781 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

Luo, Y., Bolon, B., Kahn, S., Bennett, B. D., Babu-Khan, S., Denis, P., Fan, W., Kha, H., Zhang, J., Gong, Y., Martin, L., Louis, J. C., Yan, Q., Richards, W. G., Citron, M. & Vassar, R., 2001, In : Nature neuroscience. 4, 3, p. 231-232 2 p.

Research output: Contribution to journalArticle

884 Scopus citations

MicroRNA genes are frequently located near mouse cancer susceptibility loci

Sevignani, C., Calin, G. A., Nnadi, S. C., Shimizu, M., Davuluri, R. V., Hyslop, T., Demant, P., Croce, C. M. & Siracusa, L. D., May 8 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 19, p. 8017-8022 6 p.

Research output: Contribution to journalArticle

125 Scopus citations

Migraine associated vertigo

Hain, T. C. & Cherchi, M., Jan 1 2019, In : Advances in oto-rhino-laryngology. 82, p. 119-126 8 p.

Research output: Contribution to journalArticle

MiR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-α in human breast cancer cells

Spizzo, R., Nicoloso, M. S., Lupini, L., Lu, Y., Fogarty, J., Rossi, S., Zagatti, B., Fabbri, M., Veronese, A., Liu, X., Davuluri, R., Croce, C. M., Mills, G., Negrini, M. & Calin, G. A., Feb 1 2010, In : Cell Death and Differentiation. 17, 2, p. 246-254 9 p.

Research output: Contribution to journalArticle

189 Scopus citations

MiR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma

Mathew, L. K., Skuli, N., Mucaj, V., Lee, S. S., Zinn, P. O., Sathyan, P., Imtiyaz, H. Z., Zhang, Z., Davuluri, R. V., Rao, S., Venneti, S., Lal, P., Lathia, J. D., Rich, J. N., Keith, B., Minn, A. J. & Simon, M. C., Jan 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1, p. 291-296 6 p.

Research output: Contribution to journalArticle

70 Scopus citations

Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice

Hurez, V., Daniel, B. J., Sun, L., Liu, A. J., Ludwig, S. M., Kious, M. J., Thibodeaux, S. R., Pandeswara, S., Murthy, K., Livi, C. B., Wall, S., Brumlik, M. J., Shin, T., Zhang, B. & Curiel, T. J., Apr 15 2012, In : Cancer Research. 72, 8, p. 2089-2099 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

MNK inhibition disrupts mesenchymal glioma stem cells and prolongs survival in a mouse model of glioblastoma

Bell, J. B., Eckerdt, F. D., Alley, K., Magnusson, L. P., Hussain, H., Bi, Y., Arslan, A. D., Clymer, J., Alvarez, A. A., Goldman, S., Cheng, S. Y., Nakano, I., Horbinski, C., Davuluri, R. V., David James, C. & Platanias, L. C., Oct 1 2016, In : Molecular Cancer Research. 14, 10, p. 984-993 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
5 Scopus citations

Morphometric and Histologic Substrates of Cingulate Integrity in Elders with Exceptional Memory Capacity

Gefen, T., Peterson, M., Papastefan, S. T., Martersteck, A., Whitney, K., Rademaker, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M. M. & Geula, C., Jan 28 2015, In : Journal of Neuroscience. 35, 4, p. 1781-1791 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Motivations, challenges, and attitudes to self-management in kidney transplant recipients: A systematic review of qualitative studies

Jamieson, N. J., Hanson, C. S., Josephson, M. A., Gordon, E. J., Craig, J. C., Halleck, F., Budde, K. & Tong, A., Mar 1 2016, In : American Journal of Kidney Diseases. 67, 3, p. 461-478 18 p.

Research output: Contribution to journalArticle

44 Scopus citations

MPromDb: an integrated resource for annotation and visualization of mammalian gene promoters and ChIP-chip experimental data.

Sun, H., Palaniswamy, S. K., Pohar, T. T., Jin, V. X., Huang, T. H. M. & Davuluri, R. V., Jan 1 2006, In : Nucleic acids research. 34, Database issue, p. D98-103

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

MPromDb update 2010: An integrated resource for annotation and visualization of mammalian gene promoters and ChIP-seq experimental data

Gupta, R., Bhattacharyya, A., Agosto-Perez, F. J., Wickramasinghe, P. & Davuluri, R. V., Jan 2011, In : Nucleic acids research. 39, SUPPL. 1, p. D92-D97

Research output: Contribution to journalArticle

32 Scopus citations

Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models

Liao, F., Zhang, T. J., Jiang, H., Lefton, K. B., Robinson, G. O., Vassar, R., Sullivan, P. M. & Holtzman, D. M., Nov 10 2015, In : Acta Neuropathologica Communications. 3, 1 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease

Vassar, R., Coulombe, P. A., Degenstein, L., Albers, K. & Fuchs, E., Jan 25 1991, In : Cell. 64, 2, p. 365-380 16 p.

Research output: Contribution to journalArticle

305 Scopus citations

Naming vs knowing faces in primary progressive aphasia: A tale of 2 hemispheres

Gefen, T., Wieneke, C., Martersteck, A., Whitney, K., Weintraub, S., Mesulam, M. M. & Rogalski, E., Aug 13 2013, In : Neurology. 81, 7, p. 658-664 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Neural mechanisms of object naming and word comprehension in primary progressive aphasia

Hurley, R. S., Paller, K. A., Rogalski, E. J. & Marsel Mesulam, M., Apr 4 2012, In : Journal of Neuroscience. 32, 14, p. 4848-4855 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Neurology of anomia in the semantic variant of primary progressive aphasia

Mesulam, M., Rogalski, E., Wieneke, C., Cobia, D., Rademaker, A., Thompson, C. & Weintraub, S., Sep 2009, In : Brain. 132, 9, p. 2553-2565 13 p.

Research output: Contribution to journalArticle

85 Scopus citations
117 Scopus citations

Neuropathologic associations of learning and memory in primary progressive aphasia

Kielb, S., Cook, A., Wieneke, C., Rademaker, A., Bigio, E. H., Mesulam, M. M., Rogalski, E. & Weintraub, S., Jul 2016, In : JAMA Neurology. 73, 7, p. 846-852 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

NF-κB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes

Wang, H., Hertlein, E., Bakkar, N., Sun, H., Acharyya, S., Wang, J., Carathers, M., Davuluri, R. & Guttridge, D. C., Jun 1 2007, In : Molecular and cellular biology. 27, 12, p. 4374-4387 14 p.

Research output: Contribution to journalArticle

179 Scopus citations
5 Scopus citations

Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells

Wang, C. Z., Luo, X., Zhang, B., Song, W. X., Ni, M., Mehendale, S., Xie, J. T., Aung, H. H., He, T. C. & Yuan, C. S., Jun 1 2007, In : Cancer Chemotherapy and Pharmacology. 60, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

76 Scopus citations
1 Scopus citations
19 Scopus citations

Opportunities for genomic clinical decision support interventions

Overby, C. L., Kohane, I., Kannry, J. L., Williams, M. S., Starren, J. B., Bottinger, E., Gottesman, O., Denny, J. C., Weng, C., Tarczy-Hornoch, P. & Hripcsak, G., Oct 1 2013, In : Genetics in Medicine. 15, 10, p. 817-823 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Optimizing informed consent in living liver donors: Evaluation of a comprehension assessment tool

Gordon, E. J., Mullee, J., Butt, Z., Kang, J. & Baker, T., Oct 1 2015, In : Liver Transplantation. 21, 10, p. 1270-1279 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models

Frydman-Marom, A., Levin, A., Farfara, D., Benromano, T., Scherzer-Attali, R., Peled, S., Vassar, R., Segal, D., Gazit, E., Frenkel, D. & Ovadia, M., Feb 7 2011, In : PloS one. 6, 1, e16564.

Research output: Contribution to journalArticle

122 Scopus citations

Organocatalytic highly enantioselective synthesis of β-Formyl-α- hydroxyphosphonates

Perera, S., Naganaboina, V. K., Wang, L., Zhang, B., Guo, Q., Rout, L. & Zhao, C. G., Jul 1 2011, In : Advanced Synthesis and Catalysis. 353, 10, p. 1729-1734 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes

Liu, X., Zhao, B., Sun, L., Bhuripanyo, K., Wang, Y., Bi, Y., Davuluri, R. V., Duong, D. M., Nanavati, D., Yin, J. & Kiyokawa, H., Jan 30 2017, In : Nature communications. 8, 14286.

Research output: Contribution to journalArticle

19 Scopus citations

Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes

Aldred, M. A., Huang, Y., Liyanarachchi, S., Pellegata, N. S., Gimm, O., Jhiang, S., Davuluri, R. V., De La Chapelle, A. & Eng, C., Dec 1 2004, In : Journal of Clinical Oncology. 22, 17, p. 3531-3539 9 p.

Research output: Contribution to journalArticle

121 Scopus citations

Parental leave: Comparing children's hospitals with Fortune 500 companies

Weiss, A. H., Gordon, E. J. & O'Connor, M. E., Jul 1 1998, In : Archives of Pediatrics and Adolescent Medicine. 152, 7, p. 629-633 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Parental perceptions toward digital imaging and telemedicine for retinopathy of prematurity management

Lee, J. Y., Du, Y. E., Coki, O., Flynn, J. T., Starren, J. & Chiang, M. F., Jan 1 2010, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 248, 1, p. 141-147 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Participatory design with children in the development of a support system for patient-centered care in pediatric oncology

Ruland, C. M., Starren, J. & Vatne, T. M., Aug 1 2008, In : Journal of Biomedical Informatics. 41, 4, p. 624-635 12 p.

Research output: Contribution to journalArticle

83 Scopus citations

Patient-nephrologist discussions about kidney transplantation as a treatment option

Gordon, E. & Sehgal, A., Jan 1 2000, In : Advances in Renal Replacement Therapy. 7, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Perceived low-quality communication is not associated with greater frequency of requests for ethics consultation: Null findings from an empirical study

Volpe, R. L., Benrud, J., Gordon, E. J. & Green, M. J., Oct 1 2016, In : AJOB Empirical Bioethics. 7, 4, p. 235-239 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

PGS: A tool for association study of high-dimensional microRNA expression data with repeated measures

Zheng, Y., Fei, Z., Zhang, W., Starren, J. B., Liu, L., Baccarelli, A. A., Li, Y. & Hou, L., Apr 2 2014, In : Bioinformatics. 30, 19, p. 2802-2807 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pharmacogenomic clinical decision support design and multi-site process outcomes analysis in the eMERGE Network

Herr, T. M., Peterson, J. F., Rasmussen, L. V., Caraballo, P. J., Peissig, P. L. & Starren, J. B., Jan 1 2019, In : Journal of the American Medical Informatics Association. 26, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis

O'Connor, T., Sadleir, K. R., Maus, E., Velliquette, R. A., Zhao, J., Cole, S. L., Eimer, W. A., Hitt, B., Bembinster, L. A., Lammich, S., Lichtenthaler, S. F., Hébert, S. S., De Strooper, B., Haass, C., Bennett, D. A. & Vassar, R., Dec 26 2008, In : Neuron. 60, 6, p. 988-1009 22 p.

Research output: Contribution to journalArticle

293 Scopus citations

Picomole assay for Nτ-methylhistidine by gas chromatography-Mass spectrometry

Matthews, D. E., Starren, J. B., Drexler, A. J., Kipnis, D. M. & Bier, D. M., Jan 15 1981, In : Analytical Biochemistry. 110, 2, p. 308-317 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Platform-independent classification system for predicting high-grade serous ovarian carcinoma molecular subtypes

Shilpi, A., Kandpal, M., Ji, Y., Seagle, BL. & Davuluri, RV., Apr 3 2019, In : JCO Clinical Cancer Informatics. 3, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

PML is a direct p53 target that modulates p53 effector functions

De Stanchina, E., Querido, E., Narita, M., Davuluri, R. V., Pandolfi, P. P., Ferbeyre, G. & Lowe, S. W., Feb 27 2004, In : Molecular cell. 13, 4, p. 523-535 13 p.

Research output: Contribution to journalArticle

248 Scopus citations

Polymorphic assemblies of double strands of sickle cell hemoglobin. Manifold pathways of deoxyhemoglobin S crystallization

Wellems, T. E., Vassar, R. J. & Josephs, R., Dec 25 1981, In : Journal of Molecular Biology. 153, 4, p. 1011-1026 16 p.

Research output: Contribution to journalArticle

42 Scopus citations

Practical considerations for implementing genomic information resources: Experiences from eMERGE and CSER: Experiences from eMERGE and CSER

Rasmussen, L. V., Overby, C. L., Connolly, J., Chute, C. G., Denny, J. C., Freimuth, R. R., Hartzler, A. L., Holm, I. A., Manzi, S., Pathak, J., Peissig, P. L., Smith, M. E., Williams, M. S., Shirts, B. H., Stoffel, E. M., Tarczy-Hornoch, P., Rohrer Vitek, C. R., Wolf, W. A. & Starren, J. B., Jan 1 2016, In : Applied Clinical Informatics. 7, 3, p. 870-882 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Practical Lessons in Remote Connectivity

Kouroubali, A., Starren, J., Barrows, R. C. & Clayton, P. D., Jan 1 1997, In : Journal of the American Medical Informatics Association. 4, SUPPL., p. 335-339 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Predicting ICU readmission using grouped physiological and medication trends

Xue, Y., Klabjan, D. & Luo, Y., Apr 1 2019, In : Artificial Intelligence In Medicine. 95, p. 27-37 11 p.

Research output: Contribution to journalArticle

6 Scopus citations