Life Sciences Graduate Programs

Research Output

2017

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Rocchi, A., Yamamoto, S., Ting, T., Fan, Y., Sadleir, K., Wang, Y., Zhang, W., Huang, S., Levine, B., Vassar, R. & He, C., Aug 2017, In : PLoS genetics. 13, 8, e1006962.

Research output: Contribution to journalArticle

29 Scopus citations

A mixed-methods study of veterans affairs providers’ experiences communicating with patients about the affordable care act

Martinez, R. N., Gordon, E. J., Tully, S., Silva, A., Tarlov, E., French, D. D., Huo, Z., Smith, B. M., Gordon, H. S. & Stroupe, K. T., May 2017, In : Military medicine. 182, 5, p. e1715-e1723

Research output: Contribution to journalArticle

1 Scopus citations

APP mouse models for Alzheimer's disease preclinical studies

Sasaguri, H., Nilsson, P., Hashimoto, S., Nagata, K., Saito, T., De Strooper, B., Hardy, J., Vassar, R., Winblad, B. & Saido, T. C., Sep 1 2017, In : EMBO Journal. 36, 17, p. 2473-2487 15 p.

Research output: Contribution to journalReview article

159 Scopus citations

Approach to the patient with dizziness and vertigo

Hain, T. C. & Cherchi, M., Jan 6 2017, Practical Neurology: Fifth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 207-226 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

181 Scopus citations

Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation

Calvert, A. E., Chalastanis, A., Wu, Y., Hurley, L. A., Kouri, F., Bi, Y., Kachman, M., May, J. L., Bartom, E. T., Hua, Y., Mishra, R. K., Schiltz, G. E., Dubrovskyi, O., Mazar, A. P., Peter, M. E., Zheng, H., James, C. D., Burant, C. F., Chandel, N., Davuluri, R. V. & 2 others, Horbinski, C. M. & Stegh, A. H., May 30 2017, In : Cell reports. 19, 9, p. 1858-1873 16 p.

Research output: Contribution to journalArticle

43 Scopus citations

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia

Oboudiyat, C., Gefen, T., Varelas, E., Weintraub, S., Rogalski, E., Bigio, E. H. & Mesulam, M. M., May 2017, In : Alzheimer's and Dementia. 13, 5, p. 598-601 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Combining anti-miR-155 with chemotherapy for the treatment of lung cancers

Van Roosbroeck, K., Fanini, F., Setoyama, T., Ivan, C., Rodriguez-Aguayo, C., Fuentes-Mattei, E., Xiao, L., Vannini, I., Redis, R. S., D'Abundo, L., Zhang, X., Nicoloso, M. S., Rossi, S., Gonzalez-Villasana, V., Rupaimoole, R., Ferracin, M., Morabito, F., Neri, A., Ruvolo, P. P., Ruvolo, V. R. & 20 others, Pecot, C. V., Amadori, D., Abruzzo, L., Calin, S., Wang, X., You, M. J., Ferrajoli, A., Orlowski, R., Plunkett, W., Lichtenberg, T. M., Davuluri, R. V., Berindan-Neagoe, I., Negrini, M., Wistuba, I. I., Kantarjian, H. M., Sood, A. K., Lopez-Berestein, G., Keating, M. J., Fabbri, M. & Calin, G. A., Jun 1 2017, In : Clinical Cancer Research. 23, 11, p. 2891-2904 14 p.

Research output: Contribution to journalArticle

58 Scopus citations

Comparative evaluation of isoform-level gene expression estimation algorithms for RNA-seq and exon-array platforms

Dapas, M., Kandpal, M., Bi, Y. & Davuluri, R. V., Jan 1 2017, In : Briefings in Bioinformatics. 18, 2, p. 260-269 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Effect of a mobile web app on kidney transplant candidates' knowledge about increased risk donor kidneys: A randomized controlled trial

Gordon, E. J., Sohn, M. W., Chang, C. H., Mcnatt, G., Vera, K., Beauvais, N., Warren, E., Mannon, R. B. & Ison, M. G., Jun 2017, In : Transplantation. 101, 6, p. 1167-1176 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Evaluating and improving recruitment and retention in an mHealth clinical trial: An example of iterating methods during a trial

Pfammetter, AF., Mitsos, A., Wang, S., Hood, SH. & Spring, B., Nov 2017, In : mHealth. 3, 49, p. 1-10 10 p.

Research output: Contribution to journalArticle

Fluctuating vestibulo-ocular reflex in ménière's disease

Yacovino, D. A., Hain, T. C. & Musazzi, M., Jan 1 2017, In : Otology and Neurotology. 38, 2, p. 244-247 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Functional Connectivity is Reduced in Early-stage Primary Progressive Aphasia When Atrophy is not Prominent

Bonakdarpour, B., Rogalski, E. J., Wang, A., Sridhar, J., Mesulam, M. M. & Hurley, R. S., May 1 2017, In : Alzheimer Disease and Associated Disorders. 31, 2, p. 101-106 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation

Gannon, P. J., Akay-Espinoza, C., Yee, A. C., Briand, L. A., Erickson, M. A., Gelman, B. B., Gao, Y., Haughey, N. J., Zink, M. C., Clements, J. E., Kim, N. S., Van De Walle, G., Jensen, B. K., Vassar, R., Pierce, R. C., Gill, A. J., Kolson, D. L., Diehl, J. A., Mankowski, J. L. & Jordan-Sciutto, K. L., Jan 1 2017, In : American Journal of Pathology. 187, 1, p. 91-109 19 p.

Research output: Contribution to journalArticle

14 Scopus citations

Identification of genetic and epigenetic variants associated with breast cancer prognosis by integrative bioinformatics analysis

Shilpi, A., Bi, Y., Jung, S., Patra, S. K. & Davuluri, R. V., Jan 9 2017, In : Cancer Informatics. 16

Research output: Contribution to journalArticle

7 Scopus citations

Identification of natural products with neuronal and metabolic benefits through autophagy induction

Fan, Y., Wang, N., Rocchi, A., Zhang, W., Vassar, R., Zhou, Y. & He, C., Jan 2 2017, In : Autophagy. 13, 1, p. 41-56 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Miscommunicating NOTA Can Be Costly to Living Donors

Mittelman, M., Thiessen, C., Chon, W. J., Clayville, K., Cronin, D. C., Fisher, J. S., Fry-Revere, S., Gross, J. A., Hanneman, J., Henderson, M. L., Ladin, K., Mysel, H., Sherman, L. A., Willock, L. & Gordon, E. J., Feb 1 2017, In : American Journal of Transplantation. 17, 2, p. 578-580 3 p.

Research output: Contribution to journalLetter

3 Scopus citations

Natural Language Processing for EHR-Based Pharmacovigilance: A Structured Review

Luo, Y., Thompson, W. K., Herr, T. M., Zeng, Z., Berendsen, M. A., Jonnalagadda, S. R., Carson, M. B. & Starren, J. B., Nov 1 2017, In : Drug Safety. 40, 11, p. 1075-1089 15 p.

Research output: Contribution to journalReview article

37 Scopus citations

Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes

Liu, X., Zhao, B., Sun, L., Bhuripanyo, K., Wang, Y., Bi, Y., Davuluri, R. V., Duong, D. M., Nanavati, D., Yin, J. & Kiyokawa, H., Jan 30 2017, In : Nature communications. 8, 14286.

Research output: Contribution to journalArticle

19 Scopus citations

Psychological well-being in elderly adults with extraordinary episodic memory

Maher, A. C., Kielb, S., Loyer, E., Connelley, M., Rademaker, A., Mesulam, M. M., Weintraub, S., McAdams, D., Logan, R. & Rogalski, E., Oct 2017, In : PloS one. 12, 10, e0186413.

Research output: Contribution to journalArticle

10 Scopus citations

Quantitative Comparison of Dense-Core Amyloid Plaque Accumulation in Amyloid-β Protein Precursor Transgenic Mice

Liu, P., Reichl, J. H., Rao, E. R., McNellis, B. M., Huang, E. S., Hemmy, L. S., Forster, C. L., Kuskowski, M. A., Borchelt, D. R., Vassar, R., Ashe, K. H. & Zahs, K. R., Jan 1 2017, In : Journal of Alzheimer's Disease. 56, 2, p. 743-761 19 p.

Research output: Contribution to journalArticle

5 Scopus citations

Rates of cortical atrophy in adults 80 years and older with superior vs average episodic memory

Cook, A. H., Sridhar, J., Ohm, D., Rademaker, A., Mesulam, M. M., Weintraub, S. & Rogalski, E., Apr 4 2017, In : JAMA - Journal of the American Medical Association. 317, 13, p. 1373-1375 3 p.

Research output: Contribution to journalLetter

16 Scopus citations

Seeds of Destruction: New Mechanistic Insights into the Role of Apolipoprotein E4 in Alzheimer's Disease

Vassar, R., Dec 6 2017, In : Neuron. 96, 5, p. 953-955 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations
5 Scopus citations

Stabilization of HIF-1α and HIF-2α, upregulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model

Malchenko, S., Sredni, S. T., Bi, Y., Margaryan, N. V., Boyineni, J., Mohanam, I., Tomita, T., Davuluri, R. V. & Soares, M. B., Mar 2017, In : PloS one. 12, 3, e0173106.

Research output: Contribution to journalArticle

1 Scopus citations

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs

Vannini, I., Wise, P. M., Challagundla, K. B., Plousiou, M., Raffini, M., Bandini, E., Fanini, F., Paliaga, G., Crawford, M., Ferracin, M., Ivan, C., Fabris, L., Davuluri, R. V., Guo, Z., Cortez, M. A., Zhang, X., Chen, L., Zhang, S., Fernandez-Cymering, C., Han, L. & 14 others, Carloni, S., Salvi, S., Ling, H., Murtadha, M., Neviani, P., Gitlitz, B. J., Laird-Offringa, I. A., Nana-Sinkam, P., Negrini, M., Liang, H., Amadori, D., Cimmino, A., Fabbri, M. & Calin, G. A., Dec 1 2017, In : Nature communications. 8, 1, 1801.

Research output: Contribution to journalArticle

14 Scopus citations

Vision loss in a teenage girl with postconcussion syndrome

Al-Khersan, H., Hain, T. & Grassi, M. A., Jan 1 2017, In : JAMA ophthalmology. 135, 1, p. 75-76 2 p.

Research output: Contribution to journalComment/debate

2016

A Call for Research on Individuals Who Opt out of Living Kidney Donation: Challenges and Opportunities

Thiessen, C., Kulkarni, S., Reese, P. P. & Gordon, E. J., Dec 1 2016, In : Transplantation. 100, 12, p. 2527-2532 6 p.

Research output: Contribution to journalReview article

7 Scopus citations

A culturally targeted website for hispanics/latinos about living kidney donation and transplantation: A randomized controlled trial of increased knowledge

Gordon, E. J., Feinglass, J., Carney, P., Vera, K., Olivero, M., Black, A., O'Connor, K., MacLean, J., Nichols, S., Sageshima, J., Preczewski, L. & Caicedo, J. C., Jan 1 2016, In : Transplantation. 100, 5, p. 1149-1160 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Aphasic variant of Alzheimer disease

Rogalski, E., Sridhar, J., Rader, B., Martersteck, A., Chen, K., Cobia, D., Thompson, C. K., Weintraub, S., Bigio, E. H. & Mesulam, M. M., Sep 27 2016, In : Neurology. 87, 13, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
20 Scopus citations

A question prompt sheet for adult patients with chronic kidney disease

Lederer, S., Fischer, M. J., Gordon, H. S., Wadhwa, A., Popli, S. & Gordon, E. J., Oct 19 2016, In : BMC nephrology. 17, 1, 155.

Research output: Contribution to journalArticle

7 Scopus citations

Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection

Iram, T., Trudler, D., Kain, D., Kanner, S., Galron, R., Vassar, R., Barzilai, A., Blinder, P., Fishelson, Z. & Frenkel, D., Dec 1 2016, In : Neurobiology of Disease. 96, p. 84-94 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

A website intervention to increase knowledge about living kidney donation and transplantation among hispanic/latino dialysis patients

Gordon, E. J., Feinglass, J., Carney, P., Vera, K., Olivero, M., Black, A., O'Connor, K. G., Baumgart, J. M. L. & Caicedo, J. C., Jan 1 2016, In : Progress in Transplantation. 26, 1, p. 82-91 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

BACE1 inhibition as a therapeutic strategy for Alzheimer's disease

Vassar, R., Dec 1 2016, In : Journal of Sport and Health Science. 5, 4, p. 388-390 3 p.

Research output: Contribution to journalComment/debate

10 Scopus citations

Communication Bridge: A pilot feasibility study of Internet-based speech-language therapy for individuals with progressive aphasia

Rogalski, E. J., Saxon, M., McKenna, H., Wieneke, C., Rademaker, A., Corden, M. E., Borio, K., Mesulam, M. M. & Khayum, B., Nov 1 2016, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 4, p. 213-221 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Core informatics competencies for clinical and translational scientists: What do our customers and collaborators need to know?

Valenta, A. L., Meagher, E. A., Tachinardi, U. & Starren, J. B., Jan 1 2016, In : Journal of the American Medical Informatics Association. 23, 4, p. 835-839 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Development of a model to predict breast cancer survival using data from the National Cancer Data Base

Asare, E. A., Liu, L., Hess, K. R., Gordon, E. J., Paruch, J. L., Palis, B., Dahlke, A. R., McCabe, R., Cohen, M. E., Winchester, D. P. & Bilimoria, K. Y., Feb 1 2016, In : Surgery (United States). 159, 2, p. 495-502 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium

eMERGE Network & NEIGHBOR Consortium, Sep 2016, In : PLoS genetics. 12, 9, e1006186.

Research output: Contribution to journalArticle

17 Scopus citations

Ethical considerations of transplantation and living donation for patients with alcoholic liver diseases

Singhvi, A., Welch, A. N., Levitsky, J., Singhvi, D. & Gordon, E. J., Feb 2016, In : AMA Journal of Ethics. 18, 2, p. 163-173 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Eye movements as probes of lexico-semantic processing in a patient with primary progressive aphasia

Seckin, M., Mesulam, M. M., Rademaker, A. W., Voss, J. L., Weintraub, S., Rogalski, E. J. & Hurley, R. S., Jan 2 2016, In : Neurocase. 22, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Frontotemporal networks and behavioral symptoms in primary progressive aphasia

D'Anna, L., Mesulam, M. M., Thiebaut De Schotten, M., Dell'Acqua, F., Murphy, D., Wieneke, C., Martersteck, A., Cobia, D., Rogalski, E. & Catani, M., Apr 12 2016, In : Neurology. 86, 15, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Google analytics of a pilot mass and social media campaign targeting Hispanics about living kidney donation

Gordon, E. J., Shand, J. & Black, A., Nov 1 2016, In : Internet Interventions. 6, p. 40-49 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Hypoxia-inducible factor 1-a promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3

Baumann, B., Hayashida, T., Liang, S. & Schnaper, HW., 2016, In : Kidney international. 90, p. 797-808 12 p.

Research output: Contribution to journalArticle

Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer

Jin, H. J., Jung, S., DebRoy, A. R. & Davuluri, R. V., Jan 1 2016, In : Oncotarget. 7, 34, p. 54616-54626 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques

Macyszyn, L., Akbari, H., Pisapia, J. M., Da, X., Attiah, M., Pigrish, V., Bi, Y., Pal, S., Davuluri, R. V., Roccograndi, L., Dahmane, N., Martinez-Lage, M., Biros, G., Wolf, R. L., Bilello, M., O'Rourke, D. M. & Davatzikos, C., Mar 1 2016, In : Neuro-oncology. 18, 3, p. 417-425 9 p.

Research output: Contribution to journalArticle

102 Scopus citations

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease

Yan, R., Fan, Q., Zhou, J. & Vassar, R., Jun 1 2016, In : Neuroscience and Biobehavioral Reviews. 65, p. 326-340 15 p.

Research output: Contribution to journalReview article

35 Scopus citations

Is in vivo amyloid distribution asymmetric in primary progressive aphasia?

Martersteck, A., Murphy, C., Rademaker, A., Wieneke, C., Weintraub, S., Chen, K., Mesulam, M. M. & Rogalski, E., Mar 1 2016, In : Annals of neurology. 79, 3, p. 496-501 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Live liver donors’ information needs: A qualitative study of practical implications for informed consent

Gordon, E. J., Mullee, J., Skaro, A. & Baker, T., Sep 1 2016, In : Surgery (United States). 160, 3, p. 671-682 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mal de débarquement syndrome

Hain, T. C. & Cherchi, M., Jan 1 2016, Handbook of Clinical Neurology. Elsevier B.V., p. 391-395 5 p. (Handbook of Clinical Neurology; vol. 137).

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Scopus citations