Life Sciences Graduate Programs

Research Output

2016

Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors

Levitz, J., Habrian, C., Bharill, S., Fu, Z., Vafabakhsh, R. & Isacoff, E. Y., Oct 5 2016, In : Neuron. 92, 1, p. 143-159 17 p.

Research output: Contribution to journalArticle

54 Scopus citations

MNK inhibition disrupts mesenchymal glioma stem cells and prolongs survival in a mouse model of glioblastoma

Bell, J. B., Eckerdt, F. D., Alley, K., Magnusson, L. P., Hussain, H., Bi, Y., Arslan, A. D., Clymer, J., Alvarez, A. A., Goldman, S., Cheng, S. Y., Nakano, I., Horbinski, C., Davuluri, R. V., David James, C. & Platanias, L. C., Oct 1 2016, In : Molecular Cancer Research. 14, 10, p. 984-993 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Motivations, challenges, and attitudes to self-management in kidney transplant recipients: A systematic review of qualitative studies

Jamieson, N. J., Hanson, C. S., Josephson, M. A., Gordon, E. J., Craig, J. C., Halleck, F., Budde, K. & Tong, A., Mar 1 2016, In : American Journal of Kidney Diseases. 67, 3, p. 461-478 18 p.

Research output: Contribution to journalArticle

44 Scopus citations

Neuropathologic associations of learning and memory in primary progressive aphasia

Kielb, S., Cook, A., Wieneke, C., Rademaker, A., Bigio, E. H., Mesulam, M. M., Rogalski, E. & Weintraub, S., Jul 2016, In : JAMA Neurology. 73, 7, p. 846-852 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Perceived low-quality communication is not associated with greater frequency of requests for ethics consultation: Null findings from an empirical study

Volpe, R. L., Benrud, J., Gordon, E. J. & Green, M. J., Oct 1 2016, In : AJOB Empirical Bioethics. 7, 4, p. 235-239 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Practical considerations for implementing genomic information resources: Experiences from eMERGE and CSER: Experiences from eMERGE and CSER

Rasmussen, L. V., Overby, C. L., Connolly, J., Chute, C. G., Denny, J. C., Freimuth, R. R., Hartzler, A. L., Holm, I. A., Manzi, S., Pathak, J., Peissig, P. L., Smith, M. E., Williams, M. S., Shirts, B. H., Stoffel, E. M., Tarczy-Hornoch, P., Rohrer Vitek, C. R., Wolf, W. A. & Starren, J. B., Jan 1 2016, In : Applied Clinical Informatics. 7, 3, p. 870-882 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease

Sadleir, K. R., Kandalepas, P. C., Buggia-Prévot, V., Nicholson, D. A., Thinakaran, G. & Vassar, R., Aug 1 2016, In : Acta Neuropathologica. 132, 2, p. 235-256 22 p.

Research output: Contribution to journalArticle

68 Scopus citations

Proof of concept demonstration of optimal composite MRI endpoints for clinical trials

Edland, S. D., Ard, M. C., Sridhar, J., Cobia, D., Martersteck, A., Mesulam, M. M. & Rogalski, E. J., Sep 1 2016, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2, 3, p. 177-181 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

US Transplant Policy Should Strengthen Bridges, Not Build Walls

Gordon, E. J. & Gill, J. S., Jan 1 2016, In : American Journal of Transplantation. 16, 6, p. 1645-1646 2 p.

Research output: Contribution to journalEditorial

3 Scopus citations
7 Scopus citations

β-Secretase Inhibition

Vassar, R., Jun 15 2016, Developing Therapeutics for Alzheimer's Disease: Progress and Challenges. Elsevier Inc, p. 39-62 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2015

Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level

Sadleir, K. R., Eimer, W. A., Cole, S. L. & Vassar, R., Jan 1 2015, In : Molecular neurodegeneration. 10, 1, 1.

Research output: Contribution to journalArticle

43 Scopus citations

Cervicogenic causes of vertigo

Hain, T. C., Feb 13 2015, In : Current Opinion in Neurology. 28, 1, p. 69-73 5 p.

Research output: Contribution to journalReview article

38 Scopus citations

Clinician perceptions of operating room to intensive care unit handoffs and implications for patient safety: A qualitative study

McElroy, L. M., MacApagal, K. R., Collins, K. M., Abecassis, M. M., Holl, J. L., Ladner, D. P. & Gordon, E. J., Oct 1 2015, In : American Journal of Surgery. 210, 4, p. 629-635 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Correction to Shift in monocyte apoptosis with increasing viral load and change in apoptosis-related ISG/Bcl2 family gene expression in chronically HIV-1-infected subjects [J Virol 89, (2015), 6970] DOI:10.1128/JVI.00735-15]

Patro, S. C., Pal, S., Bi, Y., Lynn, K., Mounzer, K. C., Kostman, J. R., Davuluri, R. V. & Montanera, L. J., Jan 1 2015, In : Journal of virology. 89, 13, 1 p.

Research output: Contribution to journalComment/debate

CSER and eMERGE: Current and potential state of the display of genetic information in the electronic health record

Shirts, B. H., Salama, J. S., Aronson, S. J., Chung, W. K., Gray, S. W., Hindorff, L. A., Jarvik, G. P., Plon, S. E., Stoffel, E. M., Tarczy-Hornoch, P. Z., Van Allen, E. M., Weck, K. E., Chute, C. G., Freimuth, R. R., Grundmeier, R. W., Hartzler, A. L., Li, R., Peissig, P. L., Peterson, J. F., Rasmussen, L. V. & 3 others, Starren, J. B., Williams, M. S. & Overby, C. L., 2015, In : Journal of the American Medical Informatics Association. 22, 6, p. 1231-1242 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Development of a Donor-Centered Approach to Risk Assessment: Rebalancing Nonmaleficence and Autonomy

Thiessen, C., Gordon, E. J., Reese, P. P. & Kulkarni, S., Sep 1 2015, In : American Journal of Transplantation. 15, 9, p. 2314-2323 10 p.

Research output: Contribution to journalReview article

20 Scopus citations

Epac2 mediates cAMP-dependent potentiation of neurotransmission in the hippocampus

Fernandes, H. B., Riordan, S., Nomura, T., Remmers, C. L., Kraniotis, S., Marshall, J. J., Kukreja, L., Vassar, R. & Contractor, A., Apr 22 2015, In : Journal of Neuroscience. 35, 16, p. 6544-6553 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
6 Scopus citations

Gene expression profiling of the human natural killer cell response to Fc receptor activation: Unique enhancement in the presence of interleukin-12

Campbell, A. R., Regan, K., Bhave, N., Pattanayak, A., Parihar, R., Stiff, A. R., Trikha, P., Scoville, S. D., Liyanarachchi, S., Kondadasula, S. V., Lele, O., Davuluri, R. V., Payne, P. R. O. & Carson, W. E., Oct 15 2015, In : BMC Medical Genomics. 8, 1, 66.

Research output: Contribution to journalArticle

7 Scopus citations

Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2

He, H., Li, W., Liyanarachchi, S., Jendrzejewski, J., Srinivas, M., Davuluri, R. V., Nagy, R. & de la Chapelle, A., Jan 1 2015, In : The Journal of clinical endocrinology and metabolism. 100, 1, p. E164-E172

Research output: Contribution to journalArticle

Genetic predisposition to papillary thyroid carcinoma: Involvement of FOXE1, TSHR, and a novel lincRNA Gene, PTCSC2

He, H., Li, W., Liyanarachchi, S., Jendrzejewski, J., Srinivas, M., Davuluri, R. V., Nagy, R. & De La Chapelle, A., Jan 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 1, p. E164-E172

Research output: Contribution to journalArticle

59 Scopus citations

Hippocampal subfield surface deformity in nonsemantic primary progressive aphasia

Christensen, A., Alpert, K., Rogalski, E., Cobia, D., Rao, J., Beg, M. F., Weintraub, S., Mesulam, M. M. & Wang, L., 2015, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification of candidate regulatory SNPs by integrative analysis for prostate cancer genome data

Jung, S., Jin, H. & Davuluri, R. V., Sep 9 2015, BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics. Association for Computing Machinery, Inc, p. 278-285 8 p. (BCB 2015 - 6th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Identification of reprogrammed myeloid cell transcriptomes in NSCLC

Durrans, A., Gao, D., Gupta, R., Fischer, K. R., Choi, H., El Rayes, T., Ryu, S., Nasar, A., Spinelli, C. F., Andrews, W., Elemento, O., Nolan, D., Stiles, B., Rafii, S., Narula, N., Davuluri, R., Altorki, N. K. & Mittal, V., Jun 5 2015, In : PloS one. 10, 6, e0129123.

Research output: Contribution to journalArticle

10 Scopus citations

Informed consent for live liver donors: A qualitative, prospective study

Gordon, E. J., Rodde, J., Skaro, A. & Baker, T., Oct 1 2015, In : Journal of Hepatology. 63, 4, p. 838-847 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Kidney donors at risk: how to inform the donor

Serur, D. & Gordon, E. J., Dec 1 2015, In : Progress in transplantation (Aliso Viejo, Calif.). 25, 4, p. 284-286 3 p.

Research output: Contribution to journalEditorial

Living donor kidney transplantation: Facilitating education about live kidney donation—recommendations from a consensus conference

Tan, J. C., Gordon, E. J., Dew, M. A., Rudow, D. L., Steiner, R. W., Woodle, E. S., Hays, R., Rodrigue, J. R. & Segev, D. L., Sep 4 2015, In : Clinical Journal of the American Society of Nephrology. 10, 9, p. 1670-1677 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Morphometric and Histologic Substrates of Cingulate Integrity in Elders with Exceptional Memory Capacity

Gefen, T., Peterson, M., Papastefan, S. T., Martersteck, A., Whitney, K., Rademaker, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M. M. & Geula, C., Jan 28 2015, In : Journal of Neuroscience. 35, 4, p. 1781-1791 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models

Liao, F., Zhang, T. J., Jiang, H., Lefton, K. B., Robinson, G. O., Vassar, R., Sullivan, P. M. & Holtzman, D. M., Nov 10 2015, In : Acta Neuropathologica Communications. 3, 1 p.

Research output: Contribution to journalArticle

20 Scopus citations

Optimizing informed consent in living liver donors: Evaluation of a comprehension assessment tool

Gordon, E. J., Mullee, J., Butt, Z., Kang, J. & Baker, T., Oct 1 2015, In : Liver Transplantation. 21, 10, p. 1270-1279 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
26 Scopus citations

Shift in monocyte apoptosis with increasing viral load and change in apoptosis-related ISG/Bcl2 family gene expression in chronically HIV-1-infected subjects

Patro, S. C., Pal, S., Bi, Y., Lynn, K., Mounzer, K. C., Kostman, J. R., Davuluri, R. V. & Montaner, L. J., Jan 1 2015, In : Journal of virology. 89, 1, p. 799-810 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Sprouty2 drives drug resistance and proliferation in Glioblastoma

Walsh, A. M., Kapoor, G. S., Buonato, J. M., Mathew, L. K., Bi, Y., Davuluri, R. V., Martinez-Lage, M., Simon, M. C., O'Rourke, D. M. & Lazzara, M. J., Aug 1 2015, In : Molecular Cancer Research. 13, 8, p. 1227-1237 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

The CARE Pathway Model for Dementia: Psychosocial and Rehabilitative Strategies for Care in Young-Onset Dementias

Morhardt, D., Weintraub, S., Khayum, B., Robinson, J., Medina, J., O'Hara, M., Mesulam, M. & Rogalski, E. J., Jun 1 2015, In : Psychiatric Clinics of North America. 38, 2, p. 333-352 20 p.

Research output: Contribution to journalReview article

10 Scopus citations
67 Scopus citations

What do pauses in narrative production reveal about the nature of word retrieval deficits in PPA?

Mack, J. E., Chandler, S. D., Meltzer-Asscher, A., Rogalski, E., Weintraub, S., Mesulam, M. M. & Thompson, C. K., Oct 1 2015, In : Neuropsychologia. 77, p. 211-222 12 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Association between the prevalence of learning disabilities and primary progressive aphasia

Rogalski, E. J., Rademaker, A., Wieneke, C., Bigio, E. H., Weintraub, S. & Mesulam, M. M., Dec 1 2014, In : JAMA Neurology. 71, 12, p. 1576-1577 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia

Mesulam, M. M., Weintraub, S., Rogalski, E. J., Wieneke, C., Geula, C. & Bigio, E. H., Apr 2014, In : Brain. 137, 4, p. 1176-1192 17 p.

Research output: Contribution to journalArticle

157 Scopus citations

Asymmetry of cortical decline in subtypes of primary progressive aphasia

Rogalski, E., Cobia, D., Martersteck, A., Rademaker, A., Wieneke, C., Weintraub, S. & Mesulam, M. M., Sep 1 2014, In : Neurology. 83, 13, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project

Overby, C. L., Rasmussen, L. V., Hartzler, A., Connolly, J. J., Peterson, J. F., Hedberg, R. M. E., Freimuth, R. R., Shirts, B. H., Denny, J. C., Larson, E. B., Chute, C. G., Jarvik, G. P., Ralston, J. D., Shuldiner, A. R., Starren, J. B., Kullo, I. J., Tarczy-Hornoch, P. & Williams, M. S., Jan 1 2014, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2014, p. 944-953 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Axonal BACE1 dynamics and targeting in hippocampal neurons: A role for Rab11 GTPase

Buggia-Prévot, V., Fernandez, C. G., Riordan, S., Vetrivel, K. S., Roseman, J., Waters, J., Bindokas, V. P., Vassar, R. & Thinakaran, G., Jan 4 2014, In : Molecular neurodegeneration. 9, 1, 1.

Research output: Contribution to journalArticle

52 Scopus citations

BACE1 inhibitor drugs in clinical trials for Alzheimer's disease

Vassar, R., Dec 24 2014, In : Alzheimer's Research and Therapy. 6, 9

Research output: Contribution to journalReview article

210 Scopus citations

Bioinformatics Approaches to the Study of MicroRNAs

Gupta, R. & Davuluri, R. V., 2014, Non-coding RNAs and Cancer. Fabbri, M. (ed.). New York: Springer, p. 165-245

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Comparison of data discretization methods for cross platform transfer of gene-expression based tumor subtyping classifier

Jung, S., Bi, Y. & Davuluri, R. V., Jul 24 2014, 2014 IEEE 4th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2014. Institute of Electrical and Electronics Engineers Inc., 6863918. (2014 IEEE 4th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation

Plasschaert, R. N., Vigneau, S., Tempera, I., Gupta, R., Maksimoska, J., Everett, L., Davuluri, R., Mamorstein, R., Lieberman, P. M., Schultz, D., Hannenhalli, S. & Bartolomei, M. S., 2014, In : Nucleic acids research. 42, 2, p. 774-789 16 p.

Research output: Contribution to journalArticle

36 Scopus citations

Design patterns for the development of electronic health record-driven phenotype extraction algorithms

Rasmussen, L. V., Thompson, W. K., Pacheco, J. A., Kho, A. N., Carrell, D. S., Pathak, J., Peissig, P. L., Tromp, G., Denny, J. C. & Starren, J. B., Jan 1 2014, In : Journal of Biomedical Informatics. 51, p. 280-286 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Erratum: CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation (Nucleic Acids Research (2014) 42 (774-789) DOI:10.1093/nar/gkt910)

Plasschaert, R. N., Vigneau, Ś., Tempera, I., Gupta, R., Maksimoska, J., Everett, L., Davuluri, R., Marmorstein, R., Lieberman, P. M., Schultz, D., Hannenhalli, S. & Bartolomei, M. S., 2014, In : Nucleic acids research. 42, 11, 1 p.

Research output: Contribution to journalComment/debate