Life Sciences Graduate Programs

Research Output

2012

Age-related changes in parahippocampal white matter integrity: A diffusion tensor imaging study

Rogalski, E., Stebbins, G. T., Barnes, C. A., Murphy, C. M., Stoub, T. R., George, S., Ferrari, C., Shah, R. C. & deToledo-Morrell, L., Jul 1 2012, In : Neuropsychologia. 50, 8, p. 1759-1765 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Aging-associated B7-DC + B cells enhance anti-tumor immunity via Th1 and Th17 induction

Tomihara, K., Shin, T., Hurez, V. J., Yagita, H., Pardoll, D. M., Zhang, B., Curiel, T. J. & Shin, T., Feb 1 2012, In : Aging Cell. 11, 1, p. 128-138 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Alternative transcription and alternative splicing in cancer

Pal, S., Gupta, R. & Davuluri, R. V., Dec 2012, In : Pharmacology and Therapeutics. 136, 3, p. 283-294 12 p.

Research output: Contribution to journalReview article

73 Scopus citations

Anatomic, clinical, and neuropsychological correlates of spelling errors in primary progressive aphasia

Shim, H. S., Hurley, R. S., Rogalski, E. & Mesulam, M. M., Jul 1 2012, In : Neuropsychologia. 50, 8, p. 1929-1935 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Approach to the patient with dizziness and vertigo

Hain, T. C., Oct 22 2012, Practical Neurology: Fourth Edition. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 152-167 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection

Deng, Z., Wang, Z., Stong, N., Plasschaert, R., Moczan, A., Chen, H. S., Hu, S., Wikramasinghe, P., Davuluri, R. V., Bartolomei, M. S., Riethman, H. & Lieberman, P. M., Oct 31 2012, In : EMBO Journal. 31, 21, p. 4165-4178 14 p.

Research output: Contribution to journalArticle

89 Scopus citations
46 Scopus citations

Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia

Gefen, T., Gasho, K., Rademaker, A., Lalehzari, M., Weintraub, S., Rogalski, E., Wieneke, C., Bigio, E., Geula, C. & Mesulam, M. M., May 2012, In : Brain. 135, 5, p. 1554-1565 12 p.

Research output: Contribution to journalArticle

81 Scopus citations

Development of an optical character recognition pipeline for handwritten form fields from an electronic health record

Rasmussen, L. V., Peissig, P. L., McCarty, C. A. & Starren, J. B., Jun 1 2012, In : Journal of the American Medical Informatics Association. 19, E1, p. e90-e95

Research output: Contribution to journalArticle

16 Scopus citations

Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice

Perez, S. E., Nadeem, M., Sadleir, K. R., Matras, J., Kelley, C. M., Counts, S. E., Vassar, R. & Mufson, E. J., Oct 9 2012, In : International Journal of Physiology, Pathophysiology and Pharmacology. 4, 3, p. 115-127 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Estimation of gene expression at isoform level from mRNA-seq data by Bayesian hierarchical modeling

Bhattacharjee, M., Gupta, R. & Davuluri, R. V., 2012, In : Frontiers in Genetics. 3, NOV, Article 239.

Research output: Contribution to journalArticle

Identification and biology of β-secretase

Kandalepas, P. C. & Vassar, R., Jan 1 2012, In : Journal of neurochemistry. 120, SUPPL. 1, p. 55-61 7 p.

Research output: Contribution to journalReview article

69 Scopus citations

Identification of host-chromosome binding sites and candidate gene targets for Kaposi's sarcoma-associated herpesvirus LANA

Lu, F., Tsai, K., Chen, H. S., Wikramasinghe, P., Davuluri, R. V., Showe, L., Domsic, J., Marmorstein, R. & Lieberman, P. M., May 1 2012, In : Journal of virology. 86, 10, p. 5752-5762 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Importance of multi-modal approaches to effectively identify cataract cases from electronic health records

Peissig, P. L., Rasmussen, L. V., Berg, R. L., Linneman, J. G., McCarty, C. A., Waudby, C., Chen, L., Denny, J. C., Wilke, R. A., Pathak, J., Carrell, D., Kho, A. N. & Starren, J. B., Mar 1 2012, In : Journal of the American Medical Informatics Association. 19, 2, p. 225-234 10 p.

Research output: Contribution to journalArticle

68 Scopus citations

Mitigating age-related immune dysfunction heightens the efficacy of tumor immunotherapy in aged mice

Hurez, V., Daniel, B. J., Sun, L., Liu, A. J., Ludwig, S. M., Kious, M. J., Thibodeaux, S. R., Pandeswara, S., Murthy, K., Livi, C. B., Wall, S., Brumlik, M. J., Shin, T., Zhang, B. & Curiel, T. J., Apr 15 2012, In : Cancer Research. 72, 8, p. 2089-2099 11 p.

Research output: Contribution to journalArticle

48 Scopus citations

Neural mechanisms of object naming and word comprehension in primary progressive aphasia

Hurley, R. S., Paller, K. A., Rogalski, E. J. & Marsel Mesulam, M., Apr 4 2012, In : Journal of Neuroscience. 32, 14, p. 4848-4855 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Proof of concept for the role of glycemic control in the early detection of infections in diabetics

Botsis, T., Lai, A. M., Hripcsak, G., Palmas, W., Starren, J. B. & Hartvigsen, G., Mar 1 2012, In : Health informatics journal. 18, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Quantitative classification of primary progressive aphasia at early and mild impairment stages

Mesulam, M. M., Wieneke, C., Thompson, C., Rogalski, E. & Weintraub, S., May 2012, In : Brain. 135, 5, p. 1537-1553 17 p.

Research output: Contribution to journalArticle

159 Scopus citations

RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion

Xiang, C., Baubet, V., Pal, S., Holderbaum, L., Tatard, V., Jiang, P., Davuluri, R. V. & Dahmane, N., Apr 1 2012, In : Cell Death and Differentiation. 19, 4, p. 692-702 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Semantic interference during object naming in agrammatic and logopenic primary progressive aphasia (PPA)

Thompson, C. K., Cho, S., Price, C., Wieneke, C., Bonakdarpour, B., Rogalski, E., Weintraub, S. & Mesulam, M. M., Mar 1 2012, In : Brain and Language. 120, 3, p. 237-250 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Sequencing and analysis of a South Asian-Indian personal genome

Gupta, R., Ratan, A., Rajesh, C., Chen, R., Kim, H. L., Burhans, R., Miller, W., Santhosh, S., Davuluri, R. V., Butte, A. J., Schuster, S. C., Seshagiri, S. & Thomas, G., Aug 31 2012, In : BMC Genomics. 13, 1, 440.

Research output: Contribution to journalArticle

19 Scopus citations
63 Scopus citations

The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type

Jendrzejewski, J., He, H., Radomska, H. S., Li, W., Tomsic, J., Liyanarachchi, S., Davuluri, R. V., Nagy, R. & De La Chapelle, A., May 29 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 22, p. 8646-8651 6 p.

Research output: Contribution to journalArticle

173 Scopus citations

β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects

Hitt, B., Riordan, S. M., Kukreja, L., Eimer, W. A., Rajapaksha, T. W. & Vassar, R., Nov 9 2012, In : Journal of Biological Chemistry. 287, 46, p. 38408-38425 18 p.

Research output: Contribution to journalArticle

95 Scopus citations
2011

Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development

Pal, S., Gupta, R., Kim, H., Wickramasinghe, P., Baubet, V., Showe, L. C., Dahmane, N. & Davuluri, R. V., Aug 2011, In : Genome research. 21, 8, p. 1260-1272 13 p.

Research output: Contribution to journalArticle

115 Scopus citations

Alzheimer’s therapy: A BACE in the hand?

Vassar, R. & Ishiura, S., Aug 2011, In : Nature Medicine. 17, 8, 1 p.

Research output: Contribution to journalArticle

Amyloid-β42 alters apolipoprotein E solubility in brains of mice with five familial AD mutations

Youmans, K. L., Leung, S., Zhang, J., Maus, E., Baysac, K., Bu, G., Vassar, R., Yu, C. & LaDu, M. J., Mar 15 2011, In : Journal of Neuroscience Methods. 196, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Anatomy of language impairments in primary progressive aphasia

Rogalski, E. J., Cobia, D., Harrison, T. M., Wieneke, C., Thompson, C. K., Weintraub, S. & Mesulam, M. M., Mar 2 2011, In : Journal of Neuroscience. 31, 9, p. 3344-3350 7 p.

Research output: Contribution to journalArticle

122 Scopus citations

Anticipating and addressing the unintended consequences of health IT and policy: A report from the AMIA 2009 Health Policy Meeting

Bloomrosen, M., Starren, J., Lorenzi, N. M., Ash, J. S., Patel, V. L. & Shortliffe, E. H., Jan 1 2011, In : Journal of the American Medical Informatics Association. 18, 1, p. 82-90 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

ApoE E4 is a Susceptibility Factor in Amnestic but Not Aphasic Dementias

Rogalski, E. J., Rademaker, A., Harrison, T. M., Helenowski, I., Johnson, N., Bigio, E., Mishra, M., Weintraub, S. & Mesulam, M. M., Apr 1 2011, In : Alzheimer Disease and Associated Disorders. 25, 2, p. 159-163 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of b-cell chronic lymphocytic leukemia

Fabbri, M., Bottoni, A., Shimizu, M., Spizzo, R., Nicoloso, M. S., Rossi, S., Barbarotto, E., Cimmino, A., Adair, B., Wojcik, S. E., Valeri, N., Calore, F., Sampath, D., Fanini, F., Vannini, I., Musuraca, G., Dell'Aquila, M., Alder, H., Davuluri, R. V., Rassenti, L. Z. & 9 others, Negrini, M., Nakamura, T., Amadori, D., Kay, N. E., Rai, K. R., Keating, M. J., Kipps, T. J., Calin, G. A. & Croce, C. M., Jan 5 2011, In : JAMA - Journal of the American Medical Association. 305, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

226 Scopus citations

CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

Wang, L., Fan, J., Thompson, L. F., Zhang, Y., Shin, T., Curiel, T. J. & Zhang, B., Jun 1 2011, In : Journal of Clinical Investigation. 121, 6, p. 2371-2382 12 p.

Research output: Contribution to journalArticle

146 Scopus citations

Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq

Sun, H., Wu, J., Wickramasinghe, P., Pal, S., Gupta, R., Bhattacharyya, A., Agosto-Perez, F. J., Showe, L. C., Huang, T. H. M. & Davuluri, R. V., 2011, In : Nucleic acids research. 39, 1, p. 190-201 12 p.

Research output: Contribution to journalArticle

37 Scopus citations

Implementation of workflow engine technology to deliver basic clinical decision support functionality

Huser, V., Rasmussen, L. V., Oberg, R. & Starren, J. B., Apr 12 2011, In : BMC Medical Research Methodology. 11, 43.

Research output: Contribution to journalArticle

17 Scopus citations

IsoformEx: Isoform level gene expression estimation using weighted non-negative least squares from mRNA-Seq data

Kim, H., Bi, Y., Pal, S., Gupta, R. & Davuluri, R. V., Jul 27 2011, In : BMC bioinformatics. 12, 305.

Research output: Contribution to journalArticle

20 Scopus citations

Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease

Kaczorowski, C. C., Sametsky, E., Shah, S., Vassar, R. & Disterhoft, J. F., Aug 1 2011, In : Neurobiology of Aging. 32, 8, p. 1452-1465 14 p.

Research output: Contribution to journalArticle

53 Scopus citations

Medical providers' dental information needs: A baseline survey

Acharya, A., Mahnke, A., Chyou, P. H., Rottscheit, C. & Starren, J. B., Jan 1 2011, User Centred Networked Health Care - Proceedings of MIE 2011. IOS Press, p. 387-391 5 p. (Studies in Health Technology and Informatics; vol. 169).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

MPromDb update 2010: An integrated resource for annotation and visualization of mammalian gene promoters and ChIP-seq experimental data

Gupta, R., Bhattacharyya, A., Agosto-Perez, F. J., Wickramasinghe, P. & Davuluri, R. V., Jan 2011, In : Nucleic acids research. 39, SUPPL. 1, p. D92-D97

Research output: Contribution to journalArticle

32 Scopus citations

Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models

Frydman-Marom, A., Levin, A., Farfara, D., Benromano, T., Scherzer-Attali, R., Peled, S., Vassar, R., Segal, D., Gazit, E., Frenkel, D. & Ovadia, M., Feb 7 2011, In : PloS one. 6, 1, e16564.

Research output: Contribution to journalArticle

122 Scopus citations

Organocatalytic highly enantioselective synthesis of β-Formyl-α- hydroxyphosphonates

Perera, S., Naganaboina, V. K., Wang, L., Zhang, B., Guo, Q., Rout, L. & Zhao, C. G., Jul 1 2011, In : Advanced Synthesis and Catalysis. 353, 10, p. 1729-1734 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Progression of language decline and cortical atrophy in subtypes of primary progressive aphasia

Rogalski, E., Cobia, D., Harrison, T. M., Wieneke, C., Weintraub, S. & Mesulam, M. M., May 24 2011, In : Neurology. 76, 21, p. 1804-1810 7 p.

Research output: Contribution to journalArticle

127 Scopus citations
74 Scopus citations

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

Zhao, J., O'Connor, T. & Vassar, R., Nov 2 2011, In : Journal of neuroinflammation. 8, 150.

Research output: Contribution to journalArticle

172 Scopus citations

The role of nonverbal and verbal communication in a multimedia informed consent process

Plasek, J. M., Pieczkiewicz, D. S., Mahnke, A. N., McCarty, C. A., Starren, J. B. & Westra, B. L., Dec 1 2011, In : Applied Clinical Informatics. 2, 2, p. 240-249 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

The -secretase enzyme BACE1 as a therapeutic target for Alzheimer's disease

Vassar, R. & Kandalepas, P. C., May 6 2011, In : Alzheimer's Research and Therapy. 3, 3, 20.

Research output: Contribution to journalReview article

77 Scopus citations

Tree-based position weight matrix approach to model transcription factor binding site profiles

Bi, Y., Kim, H., Gupta, R. & Davuluri, R. V., Sep 2 2011, In : PloS one. 6, 9, e24210.

Research output: Contribution to journalArticle

14 Scopus citations
2010

Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data

Gupta, R., Wikramasinghe, P., Bhattacharyya, A., Perez, F. A., Pal, S. & Davuluri, R. V., Jan 18 2010, In : BMC bioinformatics. 11, SUPPLL.1, S65.

Research output: Contribution to journalArticle

21 Scopus citations

Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b+Gr-1+ cells

Tomihara, K., Guo, M., Shin, T., Sun, X., Ludwig, S. M., Brumlik, M. J., Zhang, B., Curiel, T. J. & Shin, T., Jun 1 2010, In : Journal of Immunology. 184, 11, p. 6151-6160 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses

Lin, P. Y., Sun, L., Thibodeaux, S. R., Ludwig, S. M., Vadlamudi, R. K., Hurez, V. J., Bahar, R., Kious, M. J., Livi, C. B., Wall, S. R., Chen, L., Zhang, B., Shin, T. & Curiel, T. J., Sep 1 2010, In : Journal of Immunology. 185, 5, p. 2747-2753 7 p.

Research output: Contribution to journalArticle

73 Scopus citations

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

Hitt, B. D., Jaramillo, T. C., Chetkovich, D. M. & Vassar, R., Aug 26 2010, In : Molecular neurodegeneration. 5, 1, 31.

Research output: Contribution to journalArticle

68 Scopus citations