Life Sciences Graduate Programs

Research Output

2010

Biomedical informatics for cancer research

Ochs, M. F., Casagrande, J. T. & Davuluri, R. V., Dec 1 2010, Springer US. 354 p.

Research output: Book/ReportBook

2 Scopus citations

Biomedical informatics for cancer research: Introduction

Ochs, M. F., Casagrande, J. T. & Davuluri, R. V., Dec 1 2010, Biomedical Informatics for Cancer Research. Springer US, p. 3-15 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Biomedical Informatics for Cancer Research: Springer

Ochs, M. F., Casagrande, J. T. & Davuluri, R. V., 2010, New York: Springer.

Research output: Book/ReportBook

Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

Hong, H. S., Maezawa, I., Budamagunta, M., Rana, S., Shi, A., Vassar, R., Liu, R., Lam, K. S., Cheng, R. H., Hua, D. H., Voss, J. C. & Jin, L. W., Oct 1 2010, In : Neurobiology of Aging. 31, 10, p. 1690-1699 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

CD73: A novel target for cancer immunotherapy

Zhang, B., Aug 15 2010, In : Cancer Research. 70, 16, p. 6407-6411 5 p.

Research output: Contribution to journalReview article

127 Scopus citations

CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumor-induced immune suppression

Jin, D., Fan, J., Wang, L., Thompson, L. F., Liu, A., Daniel, B. J., Shin, T., Curiel, T. J. & Zhang, B., Mar 15 2010, In : Cancer Research. 70, 6, p. 2245-2255 11 p.

Research output: Contribution to journalArticle

230 Scopus citations

Data mining of mRNA-Seq and small RNA-Seq data to find microRNA targets

Kim, H. & Davuluri, R. V., Oct 25 2010, 2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010. p. 499-501 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Diagnostic performance of a telemedicine system for ophthalmology: advantages in accuracy and speed compared to standard care

Chiang, M. F., Wang, L., Kim, D., Scott, K., Richter, G., Kane, S., Flynn, J. & Starren, J., Jan 1 2010, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2010, p. 111-115 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Estimating the expression of transcript isoforms from mRNA-seq via nonnegative least squares

Kim, H., Bi, Y. & Davuluri, R. V., Sep 6 2010, 10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010. p. 296-297 2 p. 5521668

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)

Lu, F., Wikramasinghe, P., Norseen, J., Tsai, K., Wang, P., Showe, L., Davuluri, R. V. & Lieberman, P. M., Oct 11 2010, In : Virology Journal. 7, 262.

Research output: Contribution to journalArticle

54 Scopus citations

Improving clinical trial participant tracking tools using knowledge-anchored design methodologies

Payne, P. R. O., Embi, P. J., Johnson, S. B., Mendonca, E. & Starren, J., Dec 1 2010, In : Applied Clinical Informatics. 1, 2, p. 177-196 20 p.

Research output: Contribution to journalArticle

4 Scopus citations

Medicare payments, healthcare service use, and telemedicine implementation costs in a randomized trial comparing telemedicine case management with usual care in medically underserved participants with diabetes mellitus (IDEATel)

Palmas, W., Shea, S., Starren, J., Teresi, J. A., Ganz, M. L., Burton, T. M., Pashos, C. L., Blustein, J., Field, L., Morin, P. C., Izquierdo, R. E., Silver, S., Eimicke, J. P., Lantigua, R. A. & Weinstock, R. S., Mar 1 2010, In : Journal of the American Medical Informatics Association. 17, 2, p. 196-202 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

MicroRNAs, ultraconserved genes and colorectal cancers

Rossi, S., Kopetz, S., Davuluri, R., Hamilton, S. R. & Calin, G. A., Aug 1 2010, In : International Journal of Biochemistry and Cell Biology. 42, 8, p. 1291-1297 7 p.

Research output: Contribution to journalReview article

43 Scopus citations

MiR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-α in human breast cancer cells

Spizzo, R., Nicoloso, M. S., Lupini, L., Lu, Y., Fogarty, J., Rossi, S., Zagatti, B., Fabbri, M., Veronese, A., Liu, X., Davuluri, R., Croce, C. M., Mills, G., Negrini, M. & Calin, G. A., Feb 1 2010, In : Cell Death and Differentiation. 17, 2, p. 246-254 9 p.

Research output: Contribution to journalArticle

187 Scopus citations

Parental perceptions toward digital imaging and telemedicine for retinopathy of prematurity management

Lee, J. Y., Du, Y. E., Coki, O., Flynn, J. T., Starren, J. & Chiang, M. F., Jan 1 2010, In : Graefe's Archive for Clinical and Experimental Ophthalmology. 248, 1, p. 141-147 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Promoter hypermethylation of FBXO32, a novel TGF-Β/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer

Chou, J. L., Su, H. Y., Chen, L. Y., Liao, Y. P., Hartman-Frey, C., Lai, Y. H., Yang, H. W., Deatherage, D. E., Kuo, C. T., Huang, Y. W., Yan, P. S., Hsiao, S. H., Tai, C. K., Lin, H. J. L., Davuluri, R. V., Chao, T. K., Nephew, K. P., Huang, T. H. M., Lai, H. C. & Chan, M. W. Y., Mar 1 2010, In : Laboratory Investigation. 90, 3, p. 414-425 12 p.

Research output: Contribution to journalArticle

80 Scopus citations

Quantification of the clinical modifiers impacting high-density lipoprotein cholesterol in the community: Personalized medicine research project

Wilke, R. A., Berg, R. L., Linneman, J. G., Peissig, P., Starren, J., Ritchie, M. D. & McCarty, C. A., Mar 1 2010, In : Preventive Cardiology. 13, 2, p. 63-68 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Rate of entorhinal and hippocampal atrophy in incipient and mild AD: Relation to memory function

Stoub, T. R., Rogalski, E. J., Leurgans, S., Bennett, D. A. & deToledo-Morrell, L., Jul 1 2010, In : Neurobiology of Aging. 31, 7, p. 1089-1098 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility

Nicoloso, M. S., Sun, H., Spizzo, R., Kim, H., Wickramasinghe, P., Shimizu, M., Wojcik, S. E., Ferdin, J., Kunej, T., Xiao, L., Manoukian, S., Secreto, G., Ravagnani, F., Wang, X., Radice, P., Croce, C. M., Davuluri, R. V. & Calin, G. A., Apr 1 2010, In : Cancer Research. 70, 7, p. 2789-2798 10 p.

Research output: Contribution to journalArticle

288 Scopus citations

Telemedical diagnosis of retinopathy of prematurity: Accuracy of expert versus non-expert graders

Williams, S. L., Wang, L., Kane, S. A., Lee, T. C., Weissgold, D. J., Berrocal, A. M., Rabinowitz, D., Starren, J., Flynn, J. T. & Chiang, M. F., Mar 1 2010, In : British Journal of Ophthalmology. 94, 3, p. 351-356 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

The H3K27me3 demethylase dUTX is a suppressor of notch- and Rb-dependent tumors in Drosophila

Herz, H. M., Madden, L. D., Chen, Z., Bolduc, C., Buff, E., Gupta, R., Davuluri, R., Shilatifard, A., Hariharan, I. K. & Bergmann, A., May 2010, In : Molecular and cellular biology. 30, 10, p. 2485-2497 13 p.

Research output: Contribution to journalArticle

79 Scopus citations

The secretases: Enzymes with therapeutic potential in Alzheimer disease

De Strooper, B., Vassar, R. & Golde, T., Feb 1 2010, In : Nature Reviews Neurology. 6, 2, p. 99-107 9 p.

Research output: Contribution to journalReview article

508 Scopus citations

Use of three computer training methods in elderly underserved rural patients enrolled in a diabetes telemedicine program

Robinson, K. S., Morin, P. C., Shupe, J. A. C., Izquierdo, R., Ploutz-Snyder, R., Meyer, S., Teresi, J. A., Starren, J., Shea, S. & Weinstock, R. S., May 1 2010, In : CIN - Computers Informatics Nursing. 28, 3, p. 172-177 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
2009

Ad-hoc association of pre-determined ZigBee devices

Seeling, P. & Starren, J. B., Dec 31 2009, 2009 6th Annual International Conference on Mobile and Ubiquitous Systems: Networking and Services, MobiQuitous 2009. 5326384

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Alzheimer disease Aβ production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts

Vetrivel, K. S., Meckler, X., Chen, Y., Nguyen, P. D., Seidah, N. G., Vassar, R., Wong, P. C., Fukata, M., Kounnas, M. Z. & Thinakaran, G., Feb 6 2009, In : Journal of Biological Chemistry. 284, 6, p. 3793-3803 11 p.

Research output: Contribution to journalArticle

107 Scopus citations

An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules

Qin, H., Chan, M. W. Y., Liyanarachchi, S., Balch, C., Potter, D., Souriraj, I. J., Cheng, A. S. L., Agosto-Perez, F. J., Nikonova, E. V., Yan, P. S., Lin, H. J., Nephew, K. P., Saltz, J. H., Showe, L. C., Huang, T. H. M. & Davuluri, R. V., Jul 17 2009, In : BMC systems biology. 3, 73.

Research output: Contribution to journalArticle

52 Scopus citations

A Randomized Trial Comparing Telemedicine Case Management with Usual Care in Older, Ethnically Diverse, Medically Underserved Patients with Diabetes Mellitus: 5 Year Results of the IDEATel Study

Shea, S., Weinstock, R. S., Teresi, J. A., Palmas, W., Starren, J., Cimino, J. J., Lai, A. M., Field, L., Morin, P. C., Goland, R., Izquierdo, R. E., Ebner, S., Silver, S., Petkova, E., Kong, J. & Eimicke, J. P., Jul 2009, In : Journal of the American Medical Informatics Association. 16, 4, p. 446-456 11 p.

Research output: Contribution to journalArticle

211 Scopus citations

Beta Secretase Genes

Citron, M., Vassar, R. & Bennett, BD., Sep 1 2009, In : United States Patent 7,582,465 B2.

Research output: Contribution to journalArticle

Beta Secretase Polypeptides

Citron, M., Vassar, RJ. & Bennett, BD., Aug 25 2009, In : United States Patent 7,579,180 B2.

Research output: Contribution to journalArticle

Changes in parahippocampal white matter integrity in amnestic mild cognitive impairment: A diffusion tensor imaging study

Rogalski, E. J., Murphy, C. M., Detoledo-Morrell, L., Shah, R. C., Moseley, M. E., Bammer, R. & Stebbins, G. T., Jan 1 2009, In : Behavioural Neurology. 21, 1-2, p. 51-61 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Clinical trajectories and biological features of Primary Progressive Aphasia (PPA)

Rogalski, E. J. & Mesulam, M. M., Aug 1 2009, In : Current Alzheimer Research. 6, 4, p. 331-336 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Discovery of regulatory networks in plants by linking promoter and transcription factor databases

Yilmaz, A., Palaniswamy, S., Davuluri, R. & Grotewold, E., Nov 2 2009, OCCBIO'09: 2009 Ohio Collaborative Conference on Bioinformatics. p. 61-64 4 p. 5159163

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia

Chen, S. S., Raval, A., Johnson, A. J., Hertlein, E., Liua, T. H., Jin, V. X., Sherman, M. H., Liu, S. J., Dawson, D. W., Williams, K. E., Lanasa, M., Liyanarachchi, S., Lin, T. S., Marcucci, G., Pekarsky, Y., Davuluri, R., Croce, C. M., Guttridge, D. C., Teitell, M. A., Byrd, J. C. & 1 others, Plass, C., Aug 11 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 32, p. 13433-13438 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Evaluation of a remote training approach for teaching seniors to use a telehealth system

Lai, A. M., Kaufman, D. R., Starren, J. & Shea, S., Nov 1 2009, In : International Journal of Medical Informatics. 78, 11, p. 732-744 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Image analysis for retinopathy of prematurity diagnosis

Chiang, M. F., Gelman, R., Martinez-Perez, M. E., Du, Y. E., Casper, D. S., Currie, L. M., Shah, P. D., Starren, J. & Flynn, J. T., Oct 1 2009, In : Journal of AAPOS. 13, 5, p. 438-445 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

In vitro and in vivo anticancer effects of american ginseng berry: Exploring representative compounds

Xie, J. T., Wang, C. Z., Zhang, B., Mehendale, S. R., Li, X. L., Sun, S., Han, A. H., Du, W., He, T. C. & Yuan, C. S., Sep 1 2009, In : Biological and Pharmaceutical Bulletin. 32, 9, p. 1552-1558 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Knowledge-driven analysis and data integration for high-throughput biological data

Ochs, M. F., Quackenbush, J., Davuluri, R. & Ressom, H., Dec 1 2009, Pacific Symposium on Biocomputing 2009, PSB 2009. p. 353-355 3 p. (Pacific Symposium on Biocomputing 2009, PSB 2009).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Linking vascular disorders and Alzheimer's disease: Potential involvement of BACE1

Cole, S. L. & Vassar, R., Oct 1 2009, In : Neurobiology of Aging. 30, 10, p. 1535-1544 10 p.

Research output: Contribution to journalReview article

30 Scopus citations

Neurology of anomia in the semantic variant of primary progressive aphasia

Mesulam, M., Rogalski, E., Wieneke, C., Cobia, D., Rademaker, A., Thompson, C. & Weintraub, S., Sep 2009, In : Brain. 132, 9, p. 2553-2565 13 p.

Research output: Contribution to journalArticle

85 Scopus citations

Quantitative template for subtyping primary progressive aphasia

Mesulam, M., Wieneke, C., Rogalski, E., Cobia, D., Thompson, C. & Weintraub, S., Dec 1 2009, In : Archives of Neurology. 66, 12, p. 1545-1551 7 p.

Research output: Contribution to journalArticle

162 Scopus citations

Speed of Telemedicine vs Ophthalmoscopy for Retinopathy of Prematurity Diagnosis

Richter, G. M., Sun, G., Lee, T. C., Chan, R. V. P., Flynn, J. T., Starren, J. & Chiang, M. F., Jan 1 2009, In : American journal of ophthalmology. 148, 1

Research output: Contribution to journalArticle

29 Scopus citations

Synergies and Distinctions between Computational Disciplines in Biomedical Research: Perspective from the Clinical and Translational Science Award Programs

Bernstam, E. V., Hersh, W. R., Johnson, S. B., Chute, C. G., Nguyen, H., Sim, I., Nahm, M., Weiner, M. G., Miller, P., DiLaura, R. P., Overcash, M., Lehmann, H. P., Eichmann, D., Athey, B. D., Scheuermann, R. H., Anderson, N., Starren, J., Harris, P. A., Smith, J. W., Barbour, E. & 4 others, Silverstein, J. C., Krusch, D. A., Nagarajan, R. & Becich, M. J., Jul 2009, In : Academic Medicine. 84, 7, p. 964-970 7 p.

Research output: Contribution to journalReview article

25 Scopus citations

Telemedicine for Retinopathy of Prematurity Diagnosis: Evaluation and Challenges

Richter, G. M., Williams, S. L., Starren, J., Flynn, J. T. & Chiang, M. F., Nov 1 2009, In : Survey of Ophthalmology. 54, 6, p. 671-685 15 p.

Research output: Contribution to journalReview article

71 Scopus citations

The effects of redesigning the IDEATel architecture on glucose uploads

Hilliman, C. A., Cimino, J. J., Lai, A. M., Kaufman, D. R., Starren, J. B. & Shea, S., Apr 1 2009, In : Telemedicine and e-Health. 15, 3, p. 248-254 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
100 Scopus citations

The β-secretase enzyme BACE in health and Alzheimer's disease: Regulation, cell biology, function, and therapeutic potential

Vassar, R., Kovacs, D. M., Yan, R. & Wong, P. C., Oct 14 2009, In : Journal of Neuroscience. 29, 41, p. 12787-12794 8 p.

Research output: Contribution to journalArticle

371 Scopus citations

Understanding workflow in telehealth video visits: Observations from the IDEATel project

Kaufman, D. R., Pevzner, J., Rodriguez, M., Cimino, J. J., Ebner, S., Fields, L., Moreno, V., McGuiness, C., Weinstock, R. S., Shea, S. & Starren, J., Aug 1 2009, In : Journal of Biomedical Informatics. 42, 4, p. 581-592 12 p.

Research output: Contribution to journalArticle

16 Scopus citations
2008

Aberrant transforming growth factor β1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer

Chan, M. W. Y., Huang, Y. W., Hartman-Frey, C., Kuo, C. T., Deatherage, D., Qin, H., Cheng, A. S. L., Yan, P. S., Davuluri, R. V., Huang, T. H. M., Nephew, K. P. & Lin, H. J. L., Sep 2008, In : Neoplasia. 10, 9, p. 908-919 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia

Mesulam, M., Wicklund, A., Johnson, N., Rogalski, E., Léger, G. C., Rademaker, A., Weintraub, S. & Bigio, E. H., Jun 1 2008, In : Annals of neurology. 63, 6, p. 709-719 11 p.

Research output: Contribution to journalArticle

343 Scopus citations

A microRNA component of the hypoxic response

Kulshreshtha, R., Davuluri, R. V., Calin, G. A. & Ivan, M., Apr 1 2008, In : Cell Death and Differentiation. 15, 4, p. 667-671 5 p.

Research output: Contribution to journalReview article

195 Scopus citations