Life Sciences Graduate Programs

Research Output

2008

BACE1 structure and function in health and Alzheimer's disease

Cole, S. L. & Vassar, R., Apr 1 2008, In : Current Alzheimer Research. 5, 2, p. 100-120 21 p.

Research output: Contribution to journalReview article

77 Scopus citations

Chemopreventive effects of heat-processed Panax quinquefolius root on human breast cancer cells

Wang, C. Z., Aung, H. H., Zhang, B., Sun, S., Li, X. L., He, H., Xie, J. T., He, T. C., Du, W. & Yuan, C. S., Sep 1 2008, In : Anticancer research. 28, 5 A, p. 2545-2551 7 p.

Research output: Contribution to journalArticle

64 Scopus citations
11 Scopus citations

Equilibrium between host and cancer caused by effector T cells killing tumor stroma

Zhang, B., Zhang, Y., Bowerman, N. A., Schietinger, A., Fu, Y. X., Kranz, D. M., Rowley, D. A. & Schreiber, H., Mar 1 2008, In : Cancer Research. 68, 5, p. 1563-1571 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Evaluation of the google search appliance for patient cohort discovery.

Oberg, R., Rasmussen, L., Melski, J., Peissig, P. & Starren, J., Jan 1 2008, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 1 p.

Research output: Contribution to journalArticle

4 Scopus citations

Frequency of serum creatinine changes in the absence of iodinated contrast material: Implications for studies of contrast nephrotoxicity

Newhouse, J. H., Kho, D., Rao, Q. A. & Starren, J., Aug 15 2008, In : American Journal of Roentgenology. 191, 2, p. 376-382 7 p.

Research output: Contribution to journalArticle

230 Scopus citations

Genome-wide analysis of alternative promoters of human genes using a custom promoter tiling array

Singer, G. A. C., Wu, J., Yan, P., Plass, C., Huang, T. H. M. & Davuluri, R. V., Jul 25 2008, In : BMC Genomics. 9, 349.

Research output: Contribution to journalArticle

31 Scopus citations

IFN-γ- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

Zhang, B., Karrison, T., Rowley, D. A. & Schreiber, H., Apr 1 2008, In : Journal of Clinical Investigation. 118, 4, p. 1398-1404 7 p.

Research output: Contribution to journalArticle

96 Scopus citations

Improved techniques for quantitatively comparing data visualizations.

Pieczkiewicz, D. S., Rasmussen, L. V. & Starren, J. B., Dec 1 2008, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 1 p.

Research output: Contribution to journalArticle

57 Scopus citations

In silico prediction of target SNPs affecting miR-mRNA interaction

Sun, H., Nicoloso, M. S., Bhattacharyya, A., Calin, G. A. & Davuluri, R. V., Dec 1 2008, Proceedings - 2008 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW. p. 211-214 4 p. 4686238. (Proceedings - 2008 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Intraneuronal ß-amyloid-induced neurodegeneration and Alzheimer’s dementia.

Cole, S. L. & Vassar, R., 2008, Research Progress in Alzheimer’s Disease and Dementia. Sun M.-, K. (ed.). New York: Nova Science Publishers, Inc., p. 95-134

Research output: Chapter in Book/Report/Conference proceedingChapter

Knowledge-driven analysis and data integration for high-throughput biological data

Ochs, M. F., Quackenbush, J. & Davuluri, R., Dec 1 2008, Pacific Symposium on Biocomputing 2008, PSB 2008. p. 137-140 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Living kidney donor informed consent practices vary between US and non-US centers

Parekh, A. M., Gordon, E. J., Garg, A. X., Waterman, A. D., Kulkarni, S. & Parikh, C. R., Oct 1 2008, In : Nephrology Dialysis Transplantation. 23, 10, p. 3316-3324 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Participatory design with children in the development of a support system for patient-centered care in pediatric oncology

Ruland, C. M., Starren, J. & Vatne, T. M., Aug 1 2008, In : Journal of Biomedical Informatics. 41, 4, p. 624-635 12 p.

Research output: Contribution to journalArticle

83 Scopus citations

Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis

O'Connor, T., Sadleir, K. R., Maus, E., Velliquette, R. A., Zhao, J., Cole, S. L., Eimer, W. A., Hitt, B., Bembinster, L. A., Lammich, S., Lichtenthaler, S. F., Hébert, S. S., De Strooper, B., Haass, C., Bennett, D. A. & Vassar, R., Dec 26 2008, In : Neuron. 60, 6, p. 988-1009 22 p.

Research output: Contribution to journalArticle

291 Scopus citations

Retinopathy of Prematurity Management using Single-Image vs Multiple-Image Telemedicine Examinations

Lajoie, A., Koreen, S., Wang, L., Kane, S. A., Lee, T. C., Weissgold, D. J., Berrocal, A. M., Du, Y. E., Coki, O., Flynn, J. T., Starren, J. & Chiang, M. F., Aug 2008, In : American journal of ophthalmology. 146, 2, p. 298-309.e2

Research output: Contribution to journalArticle

14 Scopus citations

Targeting the stroma by T cells to limit tumor growth

Zhang, B., Dec 1 2008, In : Cancer Research. 68, 23, p. 9570-9573 4 p.

Research output: Contribution to journalReview article

15 Scopus citations

Telemedical Diagnosis of Retinopathy of Prematurity. Intraphysician Agreement between Ophthalmoscopic Examination and Image-Based Interpretation

Scott, K. E., Kim, D. Y., Wang, L., Kane, S. A., Coki, O., Starren, J., Flynn, J. T. & Chiang, M. F., Jul 2008, In : Ophthalmology. 115, 7, p. 1222-1228.e3

Research output: Contribution to journalArticle

73 Scopus citations

The functional consequences of alternative promoter use in mammalian genomes

Davuluri, R. V., Suzuki, Y., Sugano, S., Plass, C. & Huang, T. H. M., Apr 1 2008, In : Trends in Genetics. 24, 4, p. 167-177 11 p.

Research output: Contribution to journalReview article

213 Scopus citations

The remote patient education in a telemedicine environment architecture (REPETE)

Lai, A. M., Starren, J. B., Kaufman, D. R., Mendonça, E. A., Palmas, W., Nieh, J. & Shea, S., May 1 2008, In : Telemedicine and e-Health. 14, 4, p. 355-361 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

The role of amyloid precursor protein processing by BACE1, the β-secretase, in Alzheimer disease pathophysiology

Cole, S. L. & Vassar, R., Oct 31 2008, In : Journal of Biological Chemistry. 283, 44, p. 29621-29625 5 p.

Research output: Contribution to journalShort survey

148 Scopus citations

Tumor stroma and the antitumor immune response

Zhang, B., Rowley, D. A. & Schreiber, H., Jan 1 2008, Tumor Induced Immune Suppression: Mechanisms and Therapeutic Reversal. Springer New York, p. 281-294 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

X11 proteins regulate the translocation of amyloid β-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by β-site-cleaving enzyme in brain

Saito, Y., Sano, Y., Vassar, R., Gandy, S., Nakaya, T., Yamamoto, T. & Suzuki, T., Dec 19 2008, In : Journal of Biological Chemistry. 283, 51, p. 35763-35771 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
2007

Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer

Brena, R. M., Morrison, C., Liyanarachchi, S., Jarjoura, D., Davuluri, R. V., Otterson, G. A., Reisman, D., Glaros, S., Rush, L. J. & Plass, C., Mar 1 2007, In : PLoS medicine. 4, 3, p. 572-584 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

A better way to evaluate clinical ethics consultations? An ecological approach

Gordon, E. J., Feb 1 2007, In : American Journal of Bioethics. 7, 2, p. 26-29 4 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

Adherence to Immunosuppression: A Prospective Diary Study

Gordon, E. J., Prohaska, T. R., Gallant, M. P. & Siminoff, L. A., Dec 1 2007, In : Transplantation Proceedings. 39, 10, p. 3081-3085 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

A microRNA signature of hypoxia

Kulshreshtha, R., Ferracin, M., Wojcik, S. E., Garzon, R., Alder, H., Agosto-Perez, F. J., Davuluri, R., Liu, C. G., Croce, C. M., Negrini, M., Calin, G. A. & Ivan, M., Mar 1 2007, In : Molecular and cellular biology. 27, 5, p. 1859-1867 9 p.

Research output: Contribution to journalArticle

779 Scopus citations

An update on primary progressive aphasia

Rogalski, E. & Mesulam, M., Sep 1 2007, In : Current neurology and neuroscience reports. 7, 5, p. 388-392 5 p.

Research output: Contribution to journalReview article

20 Scopus citations
1 Scopus citations

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

Ohno, M., Cole, S. L., Yasvoina, M., Zhao, J., Citron, M., Berry, R., Disterhoft, J. F. & Vassar, R., Apr 1 2007, In : Neurobiology of Disease. 26, 1, p. 134-145 12 p.

Research output: Contribution to journalArticle

205 Scopus citations

Beyond the basics: Designing a comprehensive response to low health literacy

Gordon, E. J. & Wolf, M. S., Nov 1 2007, In : American Journal of Bioethics. 7, 11, p. 11-13 3 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Bioinformatics Tools for Modeling Transcription Factor Target Genes and Epigenetic Changes

Davuluri, R. V., 2007, Gene Function Analysis Methods in Molecular Biology Volume 408. Ochs, M. F. (ed.). New York: Humana Press, p. 129-151

Research output: Chapter in Book/Report/Conference proceedingChapter

Caspase-3 Cleavage of GGA3 Stabilizes BACE: Implications for Alzheimer's Disease

Vassar, R., Jun 7 2007, In : Neuron. 54, 5, p. 671-673 3 p.

Research output: Contribution to journalShort survey

20 Scopus citations

Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells

Wang, C. Z., Xie, J. T., Zhang, B., Ni, M., Fishbein, A., Aung, H. H., Mehendale, S. R., Du, W., He, T. C. & Yuan, C. S., Nov 1 2007, In : International journal of oncology. 31, 5, p. 1149-1156 8 p.

Research output: Contribution to journalArticle

64 Scopus citations

Children's contributions to designing a communication tool for children with cancer.

Ruland, C. M., Slaughter, L., Starren, J., Vatne, T. M. & Moe, E. Y., Nov 8 2007, In : Medinfo. MEDINFO. 12, Pt 2, p. 977-982 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Conceptual knowledge acquisition in biomedicine: A methodological review

Payne, P. R. O., Mendonça, E. A., Johnson, S. B. & Starren, J. B., Oct 1 2007, In : Journal of Biomedical Informatics. 40, 5, p. 582-602 21 p.

Research output: Contribution to journalReview article

44 Scopus citations

Contextualizing Ethical Dilemmas: Ethnography for Bioethics

Gordon, E. J. & Levin, B. W., Nov 19 2007, Empirical Methods for Bioethics: A Primer. p. 83-116 34 p. (Advances in Bioethics; vol. 11).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells

Opavsky, R., Wang, S. H., Trikha, P., Raval, A., Huang, Y., Wu, Y. Z., Rodriguez, B., Keller, B., Liyanarachchi, S., Wei, G., Davuluri, R. V., Weinstein, M., Felsher, D., Ostrowski, M., Leone, G. & Plass, C., Sep 1 2007, In : PLoS genetics. 3, 9, p. 1757-1769 13 p.

Research output: Contribution to journalArticle

36 Scopus citations

Detection and remediation of medically urgent situations using telemedicine case management for older patients with diabetes mellitus

Izquierdo, R., Meyer, S., Starren, J., Goland, R., Teresi, J., Shea, S. & Weinstock, R. S., Aug 13 2007, In : Therapeutics and Clinical Risk Management. 3, 3, p. 485-489 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

False recognition of incidentally learned pictures and words in primary progressive aphasia

Rogalski, E., Blum, D., Rademaker, A. & Weintraub, S., Jan 1 2007, In : Neuropsychologia. 45, 2, p. 368-377 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification of a novel noncoding RNA gene, NAMA, that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest

Yoon, H., He, H., Nagy, R., Davuluri, R., Suster, S., Schoenberg, D., Pellegata, N. & De La Chapelle, A., Aug 15 2007, In : International Journal of Cancer. 121, 4, p. 767-775 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

Zhang, B., Bowerman, N. A., Salama, J. K., Schmidt, H., Spiotto, M. T., Schietinger, A., Yu, P., Fu, Y. X., Weichselbaum, R. R., Rowley, D. A., Kranz, D. M. & Schreiber, H., Jan 22 2007, In : Journal of Experimental Medicine. 204, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

259 Scopus citations

Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity

Huifang, M., Lesné, S., Kotilinek, L., Steidl-Nichols, J. V., Sherman, M., Younkin, L., Younkin, S., Forster, C., Sergeant, N., Delacourte, A., Vassar, R., Citron, M., Kofuji, P., Boland, L. M. & Ashe, K. H., May 8 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 19, p. 8167-8172 6 p.

Research output: Contribution to journalArticle

87 Scopus citations

MicroRNA genes are frequently located near mouse cancer susceptibility loci

Sevignani, C., Calin, G. A., Nnadi, S. C., Shimizu, M., Davuluri, R. V., Hyslop, T., Demant, P., Croce, C. M. & Siracusa, L. D., May 8 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 19, p. 8017-8022 6 p.

Research output: Contribution to journalArticle

124 Scopus citations
5 Scopus citations

NEAT-o-games: Ubiquitous activity-based gaming

Fujiki, Y., Kazakos, K., Puri, C., Pavlidis, I., Starren, J. & Levine, J., Jan 1 2007, SIGCHI Conference on Human Factors in Computing Systems 2007, CHI 2007 Extended Abstracts. Association for Computing Machinery, p. 2369-2374 6 p. (Conference on Human Factors in Computing Systems - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

18 Scopus citations

NF-κB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes

Wang, H., Hertlein, E., Bakkar, N., Sun, H., Acharyya, S., Wang, J., Carathers, M., Davuluri, R. & Guttridge, D. C., Jun 1 2007, In : Molecular and cellular biology. 27, 12, p. 4374-4387 14 p.

Research output: Contribution to journalArticle

177 Scopus citations

Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells

Wang, C. Z., Luo, X., Zhang, B., Song, W. X., Ni, M., Mehendale, S., Xie, J. T., Aung, H. H., He, T. C. & Yuan, C. S., Jun 1 2007, In : Cancer Chemotherapy and Pharmacology. 60, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

73 Scopus citations

Primary care providers' perceptions of home diabetes telemedicine care in the IDEATel project

Tudiver, F., Wolff, L. T., Morin, P. C., Teresi, J., Palmas, W., Starren, J., Shea, S. & Weinstock, R. S., Dec 1 2007, In : Journal of Rural Health. 23, 1, p. 55-61 7 p.

Research output: Contribution to journalArticle

28 Scopus citations