Life Sciences Graduate Programs

Research Output

2013

Are there susceptibility factors for primary progressive aphasia?

Rogalski, E., Weintraub, S. & Mesulam, M. M., Nov 1 2013, In : Brain and Language. 127, 2, p. 135-138 4 p.

Research output: Contribution to journalArticle

17 Scopus citations
38 Scopus citations

Bilateral vestibular loss

Hain, T. C., Cherchi, M. & Yacovino, D. A., Oct 1 2013, In : Seminars in Neurology. 33, 3, p. 195-203 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

Ling, H., Spizzo, R., Atlasi, Y., Nicoloso, M., Shimizu, M., Redis, R. S., Nishida, N., Gafà, R., Song, J., Guo, Z., Ivan, C., Barbarotto, E., De Vries, I., Zhang, X., Ferracin, M., Churchman, M., Van Galen, J. F., Beverloo, B. H., Shariati, M., Haderk, F. & 33 others, Estecio, M. R., Garcia-Manero, G., Patijn, G. A., Gotley, D. C., Bhardwaj, V., Shureiqi, I., Sen, S., Multani, A. S., Welsh, J., Yamamoto, K., Taniguchi, I., Song, M. A., Gallinger, S., Casey, G., Thibodeau, S. N., Le Marchand, L., Tiirikainen, M., Mani, S. A., Zhang, W., Davuluri, R. V., Mimori, K., Mori, M., Sieuwerts, A. M., Martens, J. W. M., Tomlinson, I., Negrini, M., Berindan-Neagoe, I., Foekens, J. A., Hamilton, S. R., Lanza, G., Kopetz, S., Fodde, R. & Calin, G. A., Sep 2013, In : Genome research. 23, 9, p. 1446-1461 16 p.

Research output: Contribution to journalArticle

368 Scopus citations

Clinical characteristics of cervicogenic-related dizziness and vertigo

Yacovino, D. A. & Hain, T. C., Oct 1 2013, In : Seminars in Neurology. 33, 3, p. 244-255 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Veeraraghavalu, K., Zhang, C., Miller, S., Hefendehl, J. K., Rajapaksha, T. W., Ulrich, J., Jucker, M., Holtzman, D. M., Tanzi, R. E., Vassar, R. & Sisodia, S. S., Jan 1 2013, In : Science. 340, 6135, 1 p.

Research output: Contribution to journalComment/debate

98 Scopus citations

Crossing the omic chasm: A time for omic ancillary systems

Starren, J. B., Williams, M. S. & Bottinger, E. P., Mar 27 2013, In : JAMA - Journal of the American Medical Association. 309, 12, p. 1237-1238 2 p.

Research output: Contribution to journalShort survey

51 Scopus citations

Elevated Aβ42 in aged, non-demented individuals with cerebral atherosclerosis

Sadleir, K. R., Bennett, D. A., Schneider, J. A. & Vassar, R., Nov 26 2013, In : Current Alzheimer Research. 10, 8, p. 785-789 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia

Glass, C., Wuertzer, C., Cui, X., Bi, Y., Davuluri, R., Xiao, Y. Y., Wilson, M., Owens, K., Zhang, Y. & Perkins, A., Jun 27 2013, In : PloS one. 8, 6, e67134.

Research output: Contribution to journalArticle

32 Scopus citations

HINCUTs in cancer: Hypoxia-induced noncoding ultraconserved transcripts

Ferdin, J., Nishida, N., Wu, X., Nicoloso, M. S., Shah, M. Y., Devlin, C., Ling, H., Shimizu, M., Kumar, K., Cortez, M. A., Ferracin, M., Bi, Y., Yang, D., Czerniak, B., Zhang, W., Schmittgen, T. D., Voorhoeve, M. P., Reginato, M. J., Negrini, M., Davuluri, R. V. & 3 others, Kunej, T., Ivan, M. & Calin, G. A., Dec 1 2013, In : Cell Death and Differentiation. 20, 12, p. 1675-1687 13 p.

Research output: Contribution to journalArticle

64 Scopus citations

Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the alzheimer disease mouse model: In vivo and in vitro studies

Avrahami, L., Farfara, D., Shaham-Kol, M., Vassar, R., Frenkel, D. & Eldar-Finkelman, H., Jan 11 2013, In : Journal of Biological Chemistry. 288, 2, p. 1295-1306 12 p.

Research output: Contribution to journalArticle

131 Scopus citations

Isoform level expression profiles provide better cancer signatures than gene level expression profiles

Zhang, Z., Pal, S., Bi, Y., Tchou, J. & Davuluri, R. V., Apr 17 2013, In : Genome Medicine. 5, 4, 33.

Research output: Contribution to journalArticle

33 Scopus citations

Naming vs knowing faces in primary progressive aphasia: A tale of 2 hemispheres

Gefen, T., Wieneke, C., Martersteck, A., Whitney, K., Weintraub, S., Mesulam, M. M. & Rogalski, E., Aug 13 2013, In : Neurology. 81, 7, p. 658-664 7 p.

Research output: Contribution to journalArticle

33 Scopus citations
117 Scopus citations
19 Scopus citations

Opportunities for genomic clinical decision support interventions

Overby, C. L., Kohane, I., Kannry, J. L., Williams, M. S., Starren, J. B., Bottinger, E., Gottesman, O., Denny, J. C., Weng, C., Tarczy-Hornoch, P. & Hripcsak, G., Oct 1 2013, In : Genetics in Medicine. 15, 10, p. 817-823 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Practical challenges in integrating genomic data into the electronic health record

Kho, A. N., Rasmussen, L. V., Connolly, J. J., Peissig, P. L., Starren, J., Hakonarson, H. & Hayes, M. G., Oct 1 2013, In : Genetics in Medicine. 15, 10, p. 772-778 7 p.

Research output: Contribution to journalReview article

43 Scopus citations

Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and alzheimer disease-like transgenic mouse models

Frost, J. L., Le, K. X., Cynis, H., Ekpo, E., Kleinschmidt, M., Palmour, R. M., Ervin, F. R., Snigdha, S., Cotman, C. W., Saido, T. C., Vassar, R. J., George-Hyslop, P. S., Ikezu, T., Schilling, S., Demuth, H. U. & Lemere, C. A., Aug 1 2013, In : American Journal of Pathology. 183, 2, p. 369-381 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques

Kandalepas, P. C., Sadleir, K. R., Eimer, W. A., Zhao, J., Nicholson, D. A. & Vassar, R., Sep 1 2013, In : Acta Neuropathologica. 126, 3, p. 329-352 24 p.

Research output: Contribution to journalArticle

124 Scopus citations

Verbal and nonverbal memory in primary progressive aphasia: The Three Words-Three Shapes Test

Weintraub, S., Rogalski, E., Shaw, E., Sawlani, S., Rademaker, A., Wieneke, C. & Mesulam, M. M., Jan 1 2013, In : Behavioural Neurology. 26, 1-2, p. 67-76 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Words and objects at the tip of the left temporal lobe in primary progressive aphasia

Mesulam, M-M., Wieneke, C., Hurley, R., Rademaker, A., Thompson, C., Weintraub, S. & Rogalski, E., Jan 2013, In : Brain. 136, p. 601618

Research output: Contribution to journalArticle

109 Scopus citations
48 Scopus citations
2014

Association between the prevalence of learning disabilities and primary progressive aphasia

Rogalski, E. J., Rademaker, A., Wieneke, C., Bigio, E. H., Weintraub, S. & Mesulam, M. M., Dec 1 2014, In : JAMA Neurology. 71, 12, p. 1576-1577 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia

Mesulam, M. M., Weintraub, S., Rogalski, E. J., Wieneke, C., Geula, C. & Bigio, E. H., Apr 2014, In : Brain. 137, 4, p. 1176-1192 17 p.

Research output: Contribution to journalArticle

157 Scopus citations

Asymmetry of cortical decline in subtypes of primary progressive aphasia

Rogalski, E., Cobia, D., Martersteck, A., Rademaker, A., Wieneke, C., Weintraub, S. & Mesulam, M. M., Sep 1 2014, In : Neurology. 83, 13, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project

Overby, C. L., Rasmussen, L. V., Hartzler, A., Connolly, J. J., Peterson, J. F., Hedberg, R. M. E., Freimuth, R. R., Shirts, B. H., Denny, J. C., Larson, E. B., Chute, C. G., Jarvik, G. P., Ralston, J. D., Shuldiner, A. R., Starren, J. B., Kullo, I. J., Tarczy-Hornoch, P. & Williams, M. S., Jan 1 2014, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. 2014, p. 944-953 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Axonal BACE1 dynamics and targeting in hippocampal neurons: A role for Rab11 GTPase

Buggia-Prévot, V., Fernandez, C. G., Riordan, S., Vetrivel, K. S., Roseman, J., Waters, J., Bindokas, V. P., Vassar, R. & Thinakaran, G., Jan 4 2014, In : Molecular neurodegeneration. 9, 1, 1.

Research output: Contribution to journalArticle

52 Scopus citations

BACE1 inhibitor drugs in clinical trials for Alzheimer's disease

Vassar, R., Dec 24 2014, In : Alzheimer's Research and Therapy. 6, 9

Research output: Contribution to journalReview article

210 Scopus citations

Bioinformatics Approaches to the Study of MicroRNAs

Gupta, R. & Davuluri, R. V., 2014, Non-coding RNAs and Cancer. Fabbri, M. (ed.). New York: Springer, p. 165-245

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Comparison of data discretization methods for cross platform transfer of gene-expression based tumor subtyping classifier

Jung, S., Bi, Y. & Davuluri, R. V., Jul 24 2014, 2014 IEEE 4th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2014. Institute of Electrical and Electronics Engineers Inc., 6863918. (2014 IEEE 4th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation

Plasschaert, R. N., Vigneau, S., Tempera, I., Gupta, R., Maksimoska, J., Everett, L., Davuluri, R., Mamorstein, R., Lieberman, P. M., Schultz, D., Hannenhalli, S. & Bartolomei, M. S., 2014, In : Nucleic acids research. 42, 2, p. 774-789 16 p.

Research output: Contribution to journalArticle

36 Scopus citations

Design patterns for the development of electronic health record-driven phenotype extraction algorithms

Rasmussen, L. V., Thompson, W. K., Pacheco, J. A., Kho, A. N., Carrell, D. S., Pathak, J., Peissig, P. L., Tromp, G., Denny, J. C. & Starren, J. B., Jan 1 2014, In : Journal of Biomedical Informatics. 51, p. 280-286 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Erratum: CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation (Nucleic Acids Research (2014) 42 (774-789) DOI:10.1093/nar/gkt910)

Plasschaert, R. N., Vigneau, Ś., Tempera, I., Gupta, R., Maksimoska, J., Everett, L., Davuluri, R., Marmorstein, R., Lieberman, P. M., Schultz, D., Hannenhalli, S. & Bartolomei, M. S., 2014, In : Nucleic acids research. 42, 11, 1 p.

Research output: Contribution to journalComment/debate

Ewald, J Richard

Hain, T. C., Jan 1 2014, Encyclopedia of the Neurological Sciences. Elsevier Inc., p. 232 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Function, therapeutic potential and cell biology of BACE proteases: Current status and future prospects

Vassar, R., Kuhn, P. H., Haass, C., Kennedy, M. E., Rajendran, L., Wong, P. C. & Lichtenthaler, S. F., Jul 2014, In : Journal of neurochemistry. 130, 1, p. 4-28 25 p.

Research output: Contribution to journalReview article

213 Scopus citations
26 Scopus citations

Genome-wide mapping of RNA pol-II promoter usage in mouse tissues by chiP-Seq

Pal, S., Gupta, R. & Davuluri, R. V., 2014, Cancer Genomics and Proteomics: Methods and Protocols. Humana Press Inc., p. 1-9 9 p. (Methods in Molecular Biology; vol. 1176).

Research output: Chapter in Book/Report/Conference proceedingChapter

Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq

Pal, S., Gupta, R. & Davuluri, R. V., 2014, Cancer Genomics and Proteomics: Methods and Protocols. Humana Press Inc., p. 1-9 9 p. (Methods in Molecular Biology; vol. 1176).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Genome-Wide Mapping of RNA Pol-II Promoter Usage in Mouse Tissues by ChIP-Seq

Sharmistha, P., Gupta, R. & Davuluri, R. V., 2014, Cancer Genomics and Proteomics Methods in Molecular Biology Volume 1176. Wajapeyee, N. (ed.). New York: Springer, p. 1-9

Research output: Chapter in Book/Report/Conference proceedingChapter

Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease

Kukreja, L., Kujoth, G. C., Prolla, T. A., Van Leuven, F. & Vassar, R., May 2 2014, In : Molecular neurodegeneration. 9, 1, 16.

Research output: Contribution to journalArticle

29 Scopus citations

Isoform-level gene signature improves prognostic stratification and accurately classifies glioblastoma subtypes

Pal, S., Bi, Y., MacYszyn, L., Showe, L. C., O'Rourke, D. M. & Davuluri, R. V., Apr 2014, In : Nucleic acids research. 42, 8, p. e64

Research output: Contribution to journalArticle

40 Scopus citations

Longitudinal neuropsychological performance of cognitive SuperAgers

Gefen, T., Shaw, E., Whitney, K., Martersteck, A., Stratton, J., Rademaker, A., Weintraub, S., Mesulam, M. M. & Rogalski, E., Jan 1 2014, In : Journal of the American Geriatrics Society. 62, 8, p. 1598-1600 3 p.

Research output: Contribution to journalLetter

26 Scopus citations

Low-Level Laser Therapy Ameliorates Disease Progression in a Mouse Model of Alzheimer’s Disease

Farfara, D., Tuby, H., Trudler, D., Doron-Mandel, E., Maltz, L., Vassar, R. J., Frenkel, D. & Oron, U., Jan 1 2014, In : Journal of Molecular Neuroscience. 55, 2, p. 430-436 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

Ng, M. C. Y., Shriner, D., Chen, B. H., Li, J., Chen, W. M., Guo, X., Liu, J., Bielinski, S. J., Yanek, L. R., Nalls, M. A., Comeau, M. E., Rasmussen-Torvik, L. J., Jensen, R. A., Evans, D. S., Sun, Y. V., An, P., Patel, S. R., Lu, Y., Long, J., Armstrong, L. L. & 32 others, Wagenknecht, L., Yang, L., Snively, B. M., Palmer, N. D., Mudgal, P., Langefeld, C. D., Keene, K. L., Freedman, B. I., Mychaleckyj, J. C., Nayak, U., Raffel, L. J., Goodarzi, M. O., Chen, Y. D. I., Taylor, H. A., Correa, A., Sims, M., Couper, D., Pankow, J. S., Boerwinkle, E., Adeyemo, A., Doumatey, A., Hayes, M. G., Starren, J., Chisholm, R. L., Greenland, P., Kho, A. N., Lowe, W. L., Smith, M. E., Thompson, W. K., Cornelis, M., The MAGIC investigators & The GIANT consortium, Aug 7 2014, In : PLoS genetics. 10, 8, e1004517.

Research output: Contribution to journalArticle

111 Scopus citations

MiR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma

Mathew, L. K., Skuli, N., Mucaj, V., Lee, S. S., Zinn, P. O., Sathyan, P., Imtiyaz, H. Z., Zhang, Z., Davuluri, R. V., Rao, S., Venneti, S., Lal, P., Lathia, J. D., Rich, J. N., Keith, B., Minn, A. J. & Simon, M. C., Jan 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1, p. 291-296 6 p.

Research output: Contribution to journalArticle

70 Scopus citations

Molecular neurodegeneration: Basic biology and disease pathways

Vassar, R. & Zheng, H., Sep 23 2014, In : Molecular neurodegeneration. 9, 1, 34.

Research output: Contribution to journalReview article

2 Scopus citations

PGS: A tool for association study of high-dimensional microRNA expression data with repeated measures

Zheng, Y., Fei, Z., Zhang, W., Starren, J. B., Liu, L., Baccarelli, A. A., Li, Y. & Hou, L., Apr 2 2014, In : Bioinformatics. 30, 19, p. 2802-2807 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Primary progressive aphasia and the evolving neurology of the language network

Mesulam, M. M., Rogalski, E. J., Wieneke, C., Hurley, R. S., Geula, C., Bigio, E. H., Thompson, C. K. & Weintraub, S., Jan 1 2014, In : Nature Reviews Neurology. 10, 10, p. 554-569 16 p.

Research output: Contribution to journalReview article

109 Scopus citations