Life Sciences Graduate Programs

Research Output

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Review article
2018

Big Data and Data Science in Critical Care

Sanchez-Pinto, L. N., Luo, Y. & Churpek, M. M., Nov 2018, In : CHEST. 154, 5, p. 1239-1248 10 p.

Research output: Contribution to journalReview article

34 Scopus citations

Bilateral vestibular weakness

Hain, T. C., Cherchi, M. & Yacovino, D. A., May 31 2018, In : Frontiers in Neurology. 9, MAY, 344.

Research output: Contribution to journalReview article

3 Scopus citations
2017

APP mouse models for Alzheimer's disease preclinical studies

Sasaguri, H., Nilsson, P., Hashimoto, S., Nagata, K., Saito, T., De Strooper, B., Hardy, J., Vassar, R., Winblad, B. & Saido, T. C., Sep 1 2017, In : EMBO Journal. 36, 17, p. 2473-2487 15 p.

Research output: Contribution to journalReview article

165 Scopus citations

Natural Language Processing for EHR-Based Pharmacovigilance: A Structured Review

Luo, Y., Thompson, W. K., Herr, T. M., Zeng, Z., Berendsen, M. A., Jonnalagadda, S. R., Carson, M. B. & Starren, J. B., Nov 1 2017, In : Drug Safety. 40, 11, p. 1075-1089 15 p.

Research output: Contribution to journalReview article

38 Scopus citations
2016

A Call for Research on Individuals Who Opt out of Living Kidney Donation: Challenges and Opportunities

Thiessen, C., Kulkarni, S., Reese, P. P. & Gordon, E. J., Dec 1 2016, In : Transplantation. 100, 12, p. 2527-2532 6 p.

Research output: Contribution to journalReview article

7 Scopus citations

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease

Yan, R., Fan, Q., Zhou, J. & Vassar, R., Jun 1 2016, In : Neuroscience and Biobehavioral Reviews. 65, p. 326-340 15 p.

Research output: Contribution to journalReview article

35 Scopus citations
2015

Cervicogenic causes of vertigo

Hain, T. C., Feb 13 2015, In : Current Opinion in Neurology. 28, 1, p. 69-73 5 p.

Research output: Contribution to journalReview article

38 Scopus citations

Development of a Donor-Centered Approach to Risk Assessment: Rebalancing Nonmaleficence and Autonomy

Thiessen, C., Gordon, E. J., Reese, P. P. & Kulkarni, S., Sep 1 2015, In : American Journal of Transplantation. 15, 9, p. 2314-2323 10 p.

Research output: Contribution to journalReview article

20 Scopus citations

The CARE Pathway Model for Dementia: Psychosocial and Rehabilitative Strategies for Care in Young-Onset Dementias

Morhardt, D., Weintraub, S., Khayum, B., Robinson, J., Medina, J., O'Hara, M., Mesulam, M. & Rogalski, E. J., Jun 1 2015, In : Psychiatric Clinics of North America. 38, 2, p. 333-352 20 p.

Research output: Contribution to journalReview article

10 Scopus citations
2014

BACE1 inhibitor drugs in clinical trials for Alzheimer's disease

Vassar, R., Dec 24 2014, In : Alzheimer's Research and Therapy. 6, 9

Research output: Contribution to journalReview article

210 Scopus citations

Function, therapeutic potential and cell biology of BACE proteases: Current status and future prospects

Vassar, R., Kuhn, P. H., Haass, C., Kennedy, M. E., Rajendran, L., Wong, P. C. & Lichtenthaler, S. F., Jul 2014, In : Journal of neurochemistry. 130, 1, p. 4-28 25 p.

Research output: Contribution to journalReview article

212 Scopus citations

Molecular neurodegeneration: Basic biology and disease pathways

Vassar, R. & Zheng, H., Sep 23 2014, In : Molecular neurodegeneration. 9, 1, 34.

Research output: Contribution to journalReview article

2 Scopus citations

Primary progressive aphasia and the evolving neurology of the language network

Mesulam, M. M., Rogalski, E. J., Wieneke, C., Hurley, R. S., Geula, C., Bigio, E. H., Thompson, C. K. & Weintraub, S., Jan 1 2014, In : Nature Reviews Neurology. 10, 10, p. 554-569 16 p.

Research output: Contribution to journalReview article

109 Scopus citations

Targeting the β secretase BACE1 for Alzheimer's disease therapy

Yan, R. & Vassar, R., Mar 1 2014, In : The Lancet Neurology. 13, 3, p. 319-329 11 p.

Research output: Contribution to journalReview article

348 Scopus citations
2013

Practical challenges in integrating genomic data into the electronic health record

Kho, A. N., Rasmussen, L. V., Connolly, J. J., Peissig, P. L., Starren, J., Hakonarson, H. & Hayes, M. G., Oct 1 2013, In : Genetics in Medicine. 15, 10, p. 772-778 7 p.

Research output: Contribution to journalReview article

43 Scopus citations
2012

Alternative transcription and alternative splicing in cancer

Pal, S., Gupta, R. & Davuluri, R. V., Dec 2012, In : Pharmacology and Therapeutics. 136, 3, p. 283-294 12 p.

Research output: Contribution to journalReview article

73 Scopus citations

Identification and biology of β-secretase

Kandalepas, P. C. & Vassar, R., Jan 1 2012, In : Journal of neurochemistry. 120, SUPPL. 1, p. 55-61 7 p.

Research output: Contribution to journalReview article

69 Scopus citations
2011

The -secretase enzyme BACE1 as a therapeutic target for Alzheimer's disease

Vassar, R. & Kandalepas, P. C., May 6 2011, In : Alzheimer's Research and Therapy. 3, 3, 20.

Research output: Contribution to journalReview article

77 Scopus citations
2010

CD73: A novel target for cancer immunotherapy

Zhang, B., Aug 15 2010, In : Cancer Research. 70, 16, p. 6407-6411 5 p.

Research output: Contribution to journalReview article

127 Scopus citations

MicroRNAs, ultraconserved genes and colorectal cancers

Rossi, S., Kopetz, S., Davuluri, R., Hamilton, S. R. & Calin, G. A., Aug 1 2010, In : International Journal of Biochemistry and Cell Biology. 42, 8, p. 1291-1297 7 p.

Research output: Contribution to journalReview article

43 Scopus citations

The secretases: Enzymes with therapeutic potential in Alzheimer disease

De Strooper, B., Vassar, R. & Golde, T., Feb 1 2010, In : Nature Reviews Neurology. 6, 2, p. 99-107 9 p.

Research output: Contribution to journalReview article

508 Scopus citations
2009

Linking vascular disorders and Alzheimer's disease: Potential involvement of BACE1

Cole, S. L. & Vassar, R., Oct 1 2009, In : Neurobiology of Aging. 30, 10, p. 1535-1544 10 p.

Research output: Contribution to journalReview article

30 Scopus citations

Synergies and Distinctions between Computational Disciplines in Biomedical Research: Perspective from the Clinical and Translational Science Award Programs

Bernstam, E. V., Hersh, W. R., Johnson, S. B., Chute, C. G., Nguyen, H., Sim, I., Nahm, M., Weiner, M. G., Miller, P., DiLaura, R. P., Overcash, M., Lehmann, H. P., Eichmann, D., Athey, B. D., Scheuermann, R. H., Anderson, N., Starren, J., Harris, P. A., Smith, J. W., Barbour, E. & 4 others, Silverstein, J. C., Krusch, D. A., Nagarajan, R. & Becich, M. J., Jul 2009, In : Academic Medicine. 84, 7, p. 964-970 7 p.

Research output: Contribution to journalReview article

25 Scopus citations

Telemedicine for Retinopathy of Prematurity Diagnosis: Evaluation and Challenges

Richter, G. M., Williams, S. L., Starren, J., Flynn, J. T. & Chiang, M. F., Nov 1 2009, In : Survey of Ophthalmology. 54, 6, p. 671-685 15 p.

Research output: Contribution to journalReview article

71 Scopus citations
2008

A microRNA component of the hypoxic response

Kulshreshtha, R., Davuluri, R. V., Calin, G. A. & Ivan, M., Apr 1 2008, In : Cell Death and Differentiation. 15, 4, p. 667-671 5 p.

Research output: Contribution to journalReview article

195 Scopus citations

BACE1 structure and function in health and Alzheimer's disease

Cole, S. L. & Vassar, R., Apr 1 2008, In : Current Alzheimer Research. 5, 2, p. 100-120 21 p.

Research output: Contribution to journalReview article

78 Scopus citations

Targeting the stroma by T cells to limit tumor growth

Zhang, B., Dec 1 2008, In : Cancer Research. 68, 23, p. 9570-9573 4 p.

Research output: Contribution to journalReview article

15 Scopus citations

The functional consequences of alternative promoter use in mammalian genomes

Davuluri, R. V., Suzuki, Y., Sugano, S., Plass, C. & Huang, T. H. M., Apr 1 2008, In : Trends in Genetics. 24, 4, p. 167-177 11 p.

Research output: Contribution to journalReview article

216 Scopus citations
2007

An update on primary progressive aphasia

Rogalski, E. & Mesulam, M., Sep 1 2007, In : Current neurology and neuroscience reports. 7, 5, p. 388-392 5 p.

Research output: Contribution to journalReview article

20 Scopus citations

Conceptual knowledge acquisition in biomedicine: A methodological review

Payne, P. R. O., Mendonça, E. A., Johnson, S. B. & Starren, J. B., Oct 1 2007, In : Journal of Biomedical Informatics. 40, 5, p. 582-602 21 p.

Research output: Contribution to journalReview article

44 Scopus citations

The basic biology of BACE1: A key therapeutic target for Alzheimer's disease

Cole, S. L. & Vassar, R., Dec 1 2007, In : Current Genomics. 8, 8, p. 509-530 22 p.

Research output: Contribution to journalReview article

51 Scopus citations
2006

Accuracy and reliability of remote retinopathy of prematurity diagnosis

Chiang, M. F., Keenan, J. D., Starren, J., Du, Y. E., Schiff, W. M., Barile, G. R., Li, J., Johnson, R. A., Hess, D. J. & Flynn, J. T., Mar 1 2006, In : Archives of Ophthalmology. 124, 3, p. 322-327 6 p.

Research output: Contribution to journalReview article

95 Scopus citations

Children, research, and guinea pigs: Reflections on a metaphor

Gordon, E. J., Yamokoski, A. H. & Kodish, E., Sep 1 2006, In : IRB Ethics and Human Research. 28, 5, p. 12-19 8 p.

Research output: Contribution to journalReview article

8 Scopus citations

Isoprenoids and Alzheimer's disease: A complex relationship

Cole, S. L. & Vassar, R., May 1 2006, In : Neurobiology of Disease. 22, 2, p. 209-222 14 p.

Research output: Contribution to journalReview article

61 Scopus citations

Organizing a series of education and support conferences for caregivers of individuals with frontotemporal dementia and primary progressive aphasia

Banks, S., Rogalski, E., Medina, J., Skoglund, A. & Morhardt, D., Oct 1 2006, In : Alzheimer's Care Quarterly. 7, 4, p. 243-250 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

The courage to stand up: The cultural politics of nurses' access to ethics consultation

Gordon, E. J. & Hamric, A. B., Sep 1 2006, In : Journal of Clinical Ethics. 17, 3, p. 231-254 24 p.

Research output: Contribution to journalReview article

24 Scopus citations

The economics and ethics of kidney transplantation: Perspectives in 2006

Kim, S. J., Gordon, E. J. & Powe, N. R., Nov 1 2006, In : Current opinion in nephrology and hypertension. 15, 6, p. 593-598 6 p.

Research output: Contribution to journalReview article

3 Scopus citations
2005
6 Scopus citations

beta-Secretase, APP and Abeta in Alzheimer's disease.

Vassar, R., 2005, In : Sub-cellular biochemistry. 38, p. 79-103 25 p.

Research output: Contribution to journalReview article

57 Scopus citations

Residents' access to ethics consultations: Knowledge, use, and perceptions

Gacki-Smith, J. & Gordon, E. J., Feb 2005, In : Academic Medicine. 80, 2, p. 168-175 8 p.

Research output: Contribution to journalReview article

22 Scopus citations

The role of nurses in installing telehealth technology in the home

Starren, J., Tsai, C., Bakken, S., Aidala, A., Morin, P. C., Hilliman, C., Weinstock, R. S., Goland, R., Teresi, J. & Shea, S., Jan 1 2005, In : CIN - Computers Informatics Nursing. 23, 4, p. 181-189 9 p.

Research output: Contribution to journalReview article

19 Scopus citations
2004

BACE1: The β-secreiase enzyme in Alzheimer's disease

Vassar, R., Apr 1 2004, In : Journal of Molecular Neuroscience. 23, 1-2, p. 105-113 9 p.

Research output: Contribution to journalReview article

241 Scopus citations
2003

Validation of a decision regret scale

Brehaut, J. C., O'Connor, A. M., Wood, T. J., Hack, T. F., Siminoff, L., Gordon, E. & Feldman-Stewart, D., Jul 1 2003, In : Medical Decision Making. 23, 4, p. 281-292 12 p.

Research output: Contribution to journalReview article

483 Scopus citations
2002

Aβ deposition is essential to AD neuropathology

Estus, S., Borchelt, D., Kindy, M. S. & Vassar, R., Jun 2002, In : Journal of Alzheimer's Disease. 4, 3, p. 133-138 6 p.

Research output: Contribution to journalReview article

8 Scopus citations

What “race” cannot tell us about access to kidney transplantation

Gordon, E. J., Jan 1 2002, In : Cambridge Quarterly of Healthcare Ethics. 11, 2, p. 134-141 8 p.

Research output: Contribution to journalReview article

10 Scopus citations
2000

An object-oriented taxonomy of medical data presentations

Starren, J. & Johnson, S. B., Jan 1 2000, In : Journal of the American Medical Informatics Association. 7, 1, p. 1-20 20 p.

Research output: Contribution to journalReview article

30 Scopus citations

Aβ-generating enzymes: Recent advances in β- and γ-secretase research

Vassar, R. & Citron, M., Jan 1 2000, In : Neuron. 27, 3, p. 419-422 4 p.

Research output: Contribution to journalReview article

250 Scopus citations