Medical Scientist Training Program

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Alzheimer Disease Medicine & Life Sciences
Amyloid Precursor Protein Secretases Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Amyloid Plaques Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Neurons Medicine & Life Sciences

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Research Output 1981 2018

4 Citations (Scopus)

BACE1 mediates HIV-associated and excitotoxic neuronal damage through an APP-dependent mechanism

Stern, A. L., Ghura, S., Gannon, P. J., Akay-Espinoza, C., Phan, J. M., Yee, A. C., Vassar, R. J., Gelman, B. B., Kolson, D. L. & Jordan-Sciutto, K. L., May 2 2018, In : Journal of Neuroscience. 38, 18, p. 4288-4300 13 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
HIV-1
Enzymes
HIV
Alzheimer Disease
1 Citation (Scopus)

ER stress is not elevated in the 5XFAD mouse model of Alzheimer’s disease

Sadleir, K. R., Popovic, J. & Vassar, R. J., Jan 1 2018, In : Journal of Biological Chemistry. 293, 48, p. 18434-18443 10 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Amyloid beta-Protein Precursor
Presenilin-1
Alzheimer Disease
Unfolded Protein Response
16 Citations (Scopus)

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Rocchi, A., Yamamoto, S., Ting, T., Fan, Y., Sadleir, K., Wang, Y., Zhang, W., Huang, S., Levine, B., Vassar, R. & He, C., Aug 1 2017, In : PLoS Genetics. 13, 8, e1006962.

Research output: Contribution to journalArticle

autophagy
cognition
Autophagy
amyloid
Alzheimer disease