Medicine, Gastroenterology Division

Grants 2001 2024

Active

The role of Bile Acids in Gastroesophageal Reflux Disease (GERD)

Kahrilas, P. J.

Ironwood Pharmaceuticals, Inc.

12/10/19 → 6/11/23

Project: Research project

Gastroesophageal Reflux
Bile Acids and Salts
Gastroenterology
Stomach
Phase II Clinical Trials

Machine Learning for Automated, Video-Based Measurement of Colonoscopy Skill to Reduce Colorectal Cancer (CRC) Risk

Keswani, R. N. & Yang, A. D.

Gordon E. and Betty I. Moore Foundation

12/5/19 → 11/12/21

Project: Research project

ZP1848-17111, A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Glepaglutide in Patients with Short Bowel Syndrome (SBS)

Stein, A. C.

Pharm-Olam International Ltd., Zealand Pharma A/S

9/26/19 → 9/29/22

Project: Research project

Northwestern University Clinical Outcome Assessment Team (NUCOAT)

Cella, D., Flores, A. M., Gershon, R., Greene, G. J., Griffith, J. W., Lai, J., Nowinski, C. J., Pandolfino, J. E., Peipert, J. D., Phillips, S. M., Shaunfield, S. L. & Taft, T. N.

Food and Drug Administration

9/10/19 → 8/31/24

Project: Research project

Outcome Assessment (Health Care)
Sarcopenia
Irritable Bowel Syndrome
Information Systems
Drug Approval

5-laser 30-parameter FACSymphony-S6 SORP Cell Sorter from BD Biosciences

Abecassis, M. M., Bharat, A., Budinger, G. S., D'Aquila, R. T., Hope, T. J., Kato, A., Le Poole, I. C., Lesniak, M. S., Luo, X., Misharin, A., Perlman, H. R., Schleimer, R. P., Singer, B., Swaminathan, S., Sznajder, J. I., Tetreault, M., Thorp, E. B. & Wunderink, R. G.

Office of the Director, National Institutes of Health

8/8/19 → 8/7/20

Project: Research project

S 6
Lasers
Translational Medical Research
Health
Therapeutics

Prot#M16-006: A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study of the Efficacy and Safety of Risankizumab in Subjects with Moderately to Severely Active Crohn's Disease (M16-006)

Bellaguarda, E. A. L.

AbbVie Inc.

7/23/19 → 7/22/22

Project: Research project

Protocol M14-234: A Multicenter, Randomized, Double-Blind, Placebo -Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis

Bellaguarda, E. A. L. & Hanauer, S. B.

AbbVie Inc.

7/23/19 → 7/23/22

Project: Research project

Pathogenic Wnt-beta catenin target genes in macrophages and fibrosis

Misharin, A., Tetreault, M., Winter, D. R. & Gottardi, C.

Yale University, National Institute of Arthritis and Musculoskeletal and Skin Diseases

7/3/19 → 6/30/20

Project: Research project

Biomechanical assessment of the esophagogastric junction and application of predictive analytics to enhance evaluation of functional dysphagia

Carlson, D. A. & Kou, W.

American College of Gastroenterology

7/1/19 → 6/30/22

Project: Research project

Esophagogastric Junction
Deglutition Disorders
Manometry
Esophageal Motility Disorders
Pressure

Prevalence and Determinants of Illness-Related Post Traumatic Stress (PTS) in Inflammatory Bowel Disease Patients

Quinton, S. & Taft, T. N.

Northwestern Memorial Hospital, Digestive Health Foundation

7/1/19 → 6/30/20

Project: Research project

Transpyloric Stenting for Refractory Gastroparesis prior to Gastric Per-Oral Endoscopic Myotomy: A Multicenter Prospective Sham Study

Aadam, A. A.

Northwestern Memorial Hospital, Digestive Health Foundation

7/1/19 → 6/30/20

Project: Research project

Semen quality in males with inflammatory bowel disease and inflammatory joint disease: Influence of ustekinumab and tofacitinib treatment

Bellaguarda, E. A. L.

Northwestern Memorial Hospital, Digestive Health Foundation

7/1/19 → 6/30/20

Project: Research project

Assessing the Effects of Opioids on the Esophagus

Carlson, D. A.

Northwestern Memorial Hospital, Digestive Health Foundation

7/1/19 → 6/30/20

Project: Research project

Molecular mechanisms involved in early eosinophilic esophagitis pathogenesis

Tetreault, M.

Northwestern Memorial Hospital, Digestive Health Foundation

7/1/19 → 6/30/20

Project: Research project

The Use of Simulation-based mastery learning to improve colonoscopy polypectomy outcomes

Barsuk, J. H., Cameron, K. A. & Komanduri, S.

Northwestern Memorial Hospital

7/1/19 → 6/30/20

Project: Research project

Protocol M15-991: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study to Assess the efficacy and Safety of Risankizumab in Subjects with Moderately to Severely Active Crohn's Disease Who failed Prior Biologic Treatment (Abbvie M15-

Bellaguarda, E. A. L.

AbbVie Inc.

6/14/19 → 6/14/22

Project: Research project

Prot# SHP647-303: A Phase 3 Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Study of SHP647 as Maintenance Therapy in Subjects With Moderate to Severe Ulcerative Colitis (FIGARO UC 303)

Hanauer, S. B.

PPD Investigator Services, LLC, Shire Human Genetic Therapies, Inc.

6/12/19 → 6/12/22

Project: Research project

Protocol SHP647-301: A Phase 3 Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Study of SHP647 as Induction Therapy in Subjects with Moderate to Severe Ulcerative Colitis (FIGARO UC 301)

Hanauer, S. B.

PPD Investigator Services, LLC, Shire Human Genetic Therapies, Inc.

6/12/19 → 6/12/22

Project: Research project

Protocol R668-EE-1774: A Phase 3, Randomized, 3-Part Study To Investigate The Efficacy And Safety Of Dupilumab In Adult And Adolescent Patients With Eosinophilic Esophagitis.

Hirano, I.

inVentiv Health Clinical, Regeneron Pharmaceuticals, Inc.

5/1/19 → 5/1/22

Project: Research project

Protocol Title: AK002-003X : A Phase 2, Multicenter, Open-Label, Extension Study to Evaluate the Safety and Tolerability of AK002 in Patients with Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis

Hirano, I.

Allakos, Inc.

3/19/19 → 3/19/22

Project: Research project

Protocol 2017.008.01: Efficacy and safety of AbGn-168H in patients with moderate to severe active, anti-TNF 􀁄 and/or anti-integrin refractory ulcerative colitis: a 26-week, open-label, multi-center, hase II proof of principle trial

Hanauer, S. B.

Parexel, AbGenomics International Inc.

1/29/19 → 1/29/22

Project: Research project

Prot#GS-US-418-4279: A Randomized, Double-blind, Placebo-controlled Phase 2 Study to Evaluate the Testicular Safety of Filgotinib in Adult Males with Moderately to Severely Active Ulcerative Colitis

Hanauer, S. B.

PRA Health Sciences, Gilead Sciences, Inc.

10/12/18 → 10/12/21

Project: Research project

Protocol VDZ-5034: Entyvio Outcomes in Real World Bio-Naïve Ulcerative Colitis and Crohn’s Disease Patients (EVOLVE)- USA Study Protocol

Bellaguarda, E. A. L.

PPD Investigator Services, LLC, Takeda Development Center Americas, Inc.

10/10/18 → 10/10/21

Project: Research project

Project for Patient Enrollment Subproject for SP0050434

Keswani, R. N.

Medical University Of South Carolina, National Institute of Diabetes, Digestive and Kidney Diseases

9/25/18 → 4/30/20

Project: Research project

Endoscopic Retrograde Cholangiopancreatography
Indomethacin
Pancreatitis
Stents
Anti-Inflammatory Agents

Stent vs. Indomethacin for Preventing Post-ERCP Pancreatitis: The SVI Trial

Keswani, R. N.

Medical University Of South Carolina, National Institute of Diabetes, Digestive and Kidney Diseases

9/25/18 → 4/30/20

Project: Research project

Endoscopic Retrograde Cholangiopancreatography
Indomethacin
Pancreatitis
Stents
Anti-Inflammatory Agents