Grants per year
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Active
Prot #ACT18064: A Parallel-Group Treatment, Phase 2a, Multicenter, Randomized, Double-Blind, PlaceboControlled Umbrella Study to Evaluate the Efficacy and Safety of Frexalimab, SAR442970, and Rilzabrutinib in Participants Aged 16 to 75 Years with Primary
Peleg, Y. A. (PD/PI)
ICON Clinical Research, LLC, Sanofi US Services Inc.
2/6/25 → 2/6/28
Project: Research project
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Prot #STU00222754: Simergent Archimedes Peritoneal Dialysis System Human Factors Summative Study Protocol
Aggarwal, V. (PD/PI)
Nemera Insight Chicago LLC, Simergent, LLC
1/10/25 → 1/10/26
Project: Research project
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Exploring the Piezo1-Itga9 Axis in Schlemm’s Canal Development and Giant Vacuole Formation
Quaggin, S. E. (PD/PI)
Association for Research in Vision and Ophthalmology
1/1/25 → 12/31/25
Project: Research project
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Prot #VX21-147-301: A Phase 2/3 Adaptive, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of VX-147 in Adult and Pediatric Subjects With APOL1-Mediated Proteinuric Kidney Disease
Ghossein, C. (PD/PI)
Vertex Pharmaceuticals Incorporated
12/13/24 → 12/13/27
Project: Research project
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Prot #1378-0006: EASi-KIDNEY: Studies of Heart & Kidney Protection with BI 690517 in Combination with Empagliflozin: A Multicenter, International, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the Aldosterone Synthase Inhibitor BI 690517
Isakova, T. (PD/PI)
Duke University, Boehringer Ingelheim Pharmaceuticals, Inc.
10/7/24 → 10/7/27
Project: Research project
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Compartment-specific manipulation of NAD+ to mitigate post-injury kidney disease.
Kapitsinou, P. (PD/PI) & Chandel, N. (Co-Investigator)
9/30/24 → 8/31/26
Project: Research project
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Cellular-level Vascular Oculomics (CVO) for monitoring systemic vascular health
Fawzi, A. A. (PD/PI), Arispe, L. (Other), Isakova, T. (Other) & Weintraub, S. (Other)
Office of the Director, National Institutes of Health
9/15/24 → 9/14/25
Project: Research project
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Intra-graft C1 esterase inhibitor therapy for deceased kidney transplantation
Friedewald, J. J. (PD/PI)
Cedars-Sinai Medical Center, National Institute of Allergy and Infectious Diseases
9/1/24 → 8/31/31
Project: Research project
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Endothelial oxygen sensing and metabolic reprogramming in AKI to CKD transition
Kapitsinou, P. (PD/PI), Chandel, N. (Co-Investigator) & Thorp, E. B. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
8/1/24 → 5/31/28
Project: Research project
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Mosaic Loss of the Y Chromosome in Cardiac Amyloidosis
Jin, J. (PD/PI) & Liu, P. (Other)
University of Virginia, National Institute on Aging
4/15/24 → 1/31/29
Project: Research project
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Prot #R5459-RT-1956: A Noninterventional Extension Study for Patients Treated in Study R5459-RT-1944 with REGN5459 or REGN5458 (BCMA x CD3 Bispecific Antibodies) Who Receive a Kidney Transplant
Friedewald, J. J. (PD/PI)
Parexel, Regeneron Pharmaceuticals, Inc.
4/10/24 → 4/10/27
Project: Research project
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Underlying immunometabolic molecular mechanisms of cardiac dysfunction and HFpEF
Thorp, E. B. (PD/PI), Chandel, N. (Co-Investigator) & Quaggin, S. E. (Co-Investigator)
4/1/24 → 3/31/28
Project: Research project
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Prot #TVTX-RE021-204: A Multicentered, Single-Group Phase 2, Exploratory, OpenLabel Study to Investigate Safety and Effect of Sparsentan in Combination with Sodium Glucose Cotransporter-2 (SGLT2) Inhibition in the Treatment of Adult Participants with Immu
Wadhwani, S. (PD/PI)
George Clinical Pty Ltd., Retrophin, Inc.
2/27/24 → 2/27/27
Project: Research project
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Prot #CAB-201-001: A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T cells (CABA-201) in Subjects with Active Systemic Lupus Erythematosus
Blanco, I. (PD/PI), Wadhwani, S. (PD/PI) & Wadhwani, S. (PD/PI)
2/26/24 → 8/30/27
Project: Research project
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Prot #KZR‑616‑202: A Phase 2b, Randomized, Controlled Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Zetomipzomib (KZR-616) 30 mg or 60 mg with Placebo in Patients with Active Lupus Nephritis
Peleg, Y. A. (PD/PI) & Wadhwani, S. (PD/PI)
PPD Investigator Services, LLC, Kezar Life Sciences, Inc.
1/26/24 → 1/26/27
Project: Research project
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Calciprotein Particles and Vascular Calcification in Patients with Chronic Kidney Disease
Isakova, T. (PD/PI)
Albert Einstein College of Medicine, National Heart, Lung, and Blood Institute
1/1/24 → 12/31/28
Project: Research project
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Development and Pilot Testing of Hypertension Management Support with EHR-Integrated Telemonitoring and Proactive Patient Messaging for Patients at High Risk from Hypertension
Persell, S. D. (PD/PI), Nishi, L. J. (Co-Investigator), Paparello, J. J. (Co-Investigator) & Petito, L. C. (Other)
11/1/23 → 3/31/25
Project: Research project
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Prot #APL2-C3G‐310: A Phase 3, Randomized, Placebo‐Controlled, Double‐Blinded, Multicenter Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients with C3 Glomerulopathy or Immune‐Complex Membranoproliferative Glomerulonephritis
Peleg, Y. A. (PD/PI)
Worldwide Clinical Trials, Inc., Apellis Pharmaceuticals, Inc.
9/25/23 → 9/25/26
Project: Research project
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13/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical Center
Gallon, L. (PD/PI) & Gallon, L. (PD/PI)
Wake Forest University Health Sciences, National Institute of Diabetes and Digestive and Kidney Diseases
9/5/23 → 5/31/28
Project: Research project
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Improving access to renal transplantation for Underserved Black Communities
Kershaw, K. N. (PD/PI), Ladner, D. P. (PD/PI), Simpson, D. C. (PD/PI), Alexandria, S. J. (Co-Investigator), Beidas, R. S. (Co-Investigator), Blemur, P. (Co-Investigator), Franklin, J. E. (Co-Investigator), Lewis, M. W. (Co-Investigator), Zhao, L. (Co-Investigator) & Zhao, L. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/23 → 6/30/28
Project: Research project
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Biomed Core
Kapitsinou, P. (Other), Kapitsinou, P. (Other) & Scott, E. A. (Other)
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/23 → 6/30/28
Project: Research project
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Administrative Core - Main
George, A. L. (PD/PI), George, A. L. (PD/PI), Judge, S. M. (PD/PI), Judge, S. M. (PD/PI), Quaggin, S. E. (PD/PI) & Quaggin, S. E. (PD/PI)
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/23 → 6/30/28
Project: Research project
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Continuation of the Chronic Renal Insufficiency Cohort (CRIC)
Isakova, T. (PD/PI)
University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases
8/15/23 → 6/30/28
Project: Research project