Medicine, Pulmonary Division

Research Output 1949 2019

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2018
1 Citation (Scopus)

A public health evaluation of 13-valent pneumococcal conjugate vaccine impact on adult disease outcomes from a randomized clinical trial in the Netherlands

Gessner, B. D., Jiang, Q., Van Werkhoven, C. H., Sings, H. L., Webber, C., Scott, D., Neuzil, K. M., O'Brien, K. L., Wunderink, R. G., Grobbee, D. E., Bonten, M. J. M. & Jodar, L., Jan 1 2018, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Conjugate Vaccines
randomized clinical trials
Netherlands
public health
Randomized Controlled Trials
1 Citation (Scopus)

A role for heat shock factor 1 in hypercapnia-induced inhibition of inflammatory cytokine expression

Lu, Z., Casalino Matsuda, M. S., Nair, A., Buchbinder, A., Budinger, GR. S., Sporn, P. H. & Gates, K. L., Jul 1 2018, In : FASEB Journal. 32, 7, p. 3614-3622 9 p.

Research output: Contribution to journalArticle

Hypercapnia
Shock
Hot Temperature
Cytokines
Interleukin-6
5 Citations (Scopus)

Association of body mass index with lung transplantation survival in the United States following implementation of the lung allocation score

Fernandez, R., Safaeinili, N., Kurihara, C., Odell, D. D., Jain, M., DeCamp Jr, M. M., Budinger, GR. S. & Bharat, A., Apr 1 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 4, p. 1871-1879.e3

Research output: Contribution to journalArticle

Lung Transplantation
Body Mass Index
Lung
Survival
Mortality
3 Citations (Scopus)

Association of free vitamin D3 concentrations and asthma treatment failures in the VIDA Trial

Lima, J. J., Castro, M., King, T. S., Lang, J. E., Ortega, V. E., Peters, S. P., Denlinger, L. C., Israel, E., Sorkness, C. A., Wechsler, M. E., Wenzel, S. E. & Smith, L. J., Oct 1 2018, In : Annals of Allergy, Asthma and Immunology. 121, 4, p. 444-450.e1

Research output: Contribution to journalArticle

Free Association
Cholecalciferol
Treatment Failure
Asthma
Confidence Intervals

A young man with fevers and an invasive mediastinal mass

Sala, M. A., Celli, D., Yeldandi, A. V., Gillespie, C. T. & Argento, A. C., Dec 1 2018, In : Annals of the American Thoracic Society. 15, 12, p. 1477-1482 6 p.

Research output: Contribution to journalArticle

Fever
11 Citations (Scopus)

Bacterial biogeography of adult airways in atopic asthma

for the National Heart, Lung and Blood Institute's 'AsthmaNet', Jun 9 2018, In : Microbiome. 6, 1, 104.

Research output: Contribution to journalArticle

Microbiota
Asthma
Sputum
Moraxella
Corynebacterium
Graft vs Host Disease
Lung
Safety
Multiple Myeloma
Bortezomib
6 Citations (Scopus)

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: A multinational point prevalence study of hospitalised patients

Restrepo, M. I., Babu, B. L., Reyes, L. F., Chalmers, J. D., Soni, N. J., Sibila, O., Faverio, P., Cilloniz, C., Rodriguez-Cintron, W., Aliberti, S., Aruj, P. K., Attorri, S., Barimboim, E., Caeiro, J. P., Garzón, M. I., Cambursano, V. H., Ceccato, A., Chertcoff, J., Lascar, F., Di Tulio, F. & 254 others, Díaz, A. C., de Vedia, L., Ganaha, M. C., Lambert, S., Lopardo, G., Luna, C. M., Malberti, A. G., Morcillo, N., Tartara, S., Pensotti, C., Pereyra, B., Scapellato, P. G., Stagnaro, J. P., Shah, S., Lötsch, F., Thalhammer, F., Anseeuw, K., Francois, C. A., Van Braeckel, E., Vincent, J. L., Djimon, M. Z., Bashi, J., Dodo, R., Nouér, S. A., Chipev, P., Encheva, M., Miteva, D., Petkova, D., Dodo Balkissou, A., Pefura Yone, E. W., Mbatchou Ngahane, B. H., Shen, N., Xu, J. F., Bustamante Rico, C. A., Buitrago, R., Pereira Paternina, F. J., Kayembe Ntumba, J. M., Carevic, V. V., Jakopovic, M., Jankovic, M., Matkovic, Z., Mitrecic, I., Bouchy Jacobsson, M. L., Bro Christensen, A., Heitmann Bødtger, U. C., Niels Meyer, C., Vestergaard Jensen, A., Baunbæk-Knudsen, G., Petersen, P. T., Andersen, S., Abd El-Wahhab, I. E., Elsayed Morsy, N., Shafiek, H., Sobh, E., Abdella Abdulsemed, K., Bertrand, F., Brun-Buisson, C., de Montmollin, E., Fartoukh, M., Messika, J., Tattevin, P., Khoury, A., Ebruke, B., Dreher, M., Kolditz, M., Meisinger, M., Pletz, M. W., Hagel, S., Rupp, J., Schaberg, T., Spielmanns, M., Creutz, P., Suttorp, N., Siaw-Lartey, B., Dimakou, K., Papapetrou, D., Tsigou, E., Ampazis, D., Kaimakamis, E., Bhatia, M., Dhar, R., D'Souza, G., Garg, R., Koul, P. A., Mahesh, P. A., Jayaraj, B. S., Narayan, K. V., Udnur, H. B., Krishnamurthy, S. B., Kant, S., Swarnakar, R., Limaye, S., Salvi, S., Golshani, K., Keatings, V. M., Martin-Loeches, I., Maor, Y., Strahilevitz, J., Battaglia, S., Carrabba, M., Ceriana, P., Confalonieri, M., Monforte, A. D., Del Prato, B., De Rosa, M., Fantini, R., Fiorentino, G., Gammino, M. A., Menzella, F., Milani, G., Nava, S., Palmiero, G., Petrino, R., Gabrielli, B., Rossi, P., Sorino, C., Steinhilber, G., Zanforlin, A., Franzetti, F., Carugati, M., Morosi, M., Monge, E., Carone, M., Patella, V., Scarlata, S., Comel, A., Kurahashi, K., Bacha, Z. A., Ugalde, D. B., Zuñiga, O. C., Villegas, J. F., Medenica, M., van de Garde, E. M. W., Raj Mihsra, D., Shrestha, P., Ridgeon, E., Awokola, B. I., Nwankwo, O. N. O., Olufunlola, A. B., Olumide, S., Ukwaja, K. N., Irfan, M., Minarowski, L., Szymon, S., Froes, F., Leuschner, P., Meireles, M., Ferrão, C., Neves, J., Ravara, S. B., Brocovschii, V., Ion, C., Rusu, D., Toma, C., Chirita, D., Dorobat, C. M., Birkun, A., Kaluzhenina, A., Almotairi, A., Ali Bukhary, Z. A., Edathodu, J., Fathy, A., Abdulaziz Enani, A. M., Mohamed, N. E., Memon, J. U., Bella, A., Bogdanović, N., Milenkovic, B., Pesut, D., Feldman, C., Yum, H. K., Borderìas, L., Bordon Garcia, N. M., Cabello Alarcón, H., Torres, A., Diaz-Brito, V., Casas, X., González, A. E., Fernández-Almira, M. L., Gallego, M., Gaspar-García, I., Del Castillo, J. G., Victoria, P. J., Martínez, E. L., de Molina, R. M., Marcos, P. J., Menéndez, R., Pando-Sandoval, A., Aymerich, C. P., de la Torre, A. L., García-Olivé, I., Rello, J., Moyano, S., Sanz, F., Rodrigo-Troyano, A., Solé-Violán, J., Uranga, A., van Boven, J. F. M., Torra, E. V., Pujol, J. A., Fiogbe, A. A., Yangui, F., Bilaceroglu, S., Dalar, L., Yilmaz, U., Bogomolov, A., Elahi, N., Dhasmana, D. J., Feneley, A., Ions, R., Skeemer, J., Woltmann, G., Hancock, C., Hill, A. T., Rudran, B., Ruiz-Buitrago, S., Campbell, M., Whitaker, P., Youzguin, A., Singanayagam, A., Allen, K. S., Brito, V., Dietz, J., Dysart, C. E., Kellie, S. M., Zablocki, C. J., MurphyMurphy, R. G., Franco-Sadud, R. A., Meier, G., Gaga, M., Holland, T. L., Bergin, S. P., Kheir, F., Landmeier, M., Lois, M., Nair, G. B., Patel, H., Saito, S., Noda, J., Hinojosa, C. I., Levine, S. M., Angel, L. F., Anzueto, A., Whitlow, K. S., Hipskind, J., Sukhija, K., Totten, V., Wunderink, R. G., Shah, R. D., Mateyo, K. J., Noriega, L., Alvarado, E., Aman, M. & Labra, L., Aug 1 2018, In : European Respiratory Journal. 52, 2, 1701190.

Research output: Contribution to journalArticle

Pseudomonas aeruginosa
Pneumonia
Cross-Sectional Studies
Anti-Bacterial Agents
Lung Diseases
3 Citations (Scopus)

Cancer-related disease factors and smoking cessation treatment: Analysis of an ongoing clinical trial

Carroll, A. J., Veluz-Wilkins, A. K., Blazekovic, S., Kalhan, R., Leone, F. T., Wileyto, E. P., Schnoll, R. A. & Hitsman, B. L., Feb 1 2018, In : Psycho-oncology. 27, 2, p. 471-476 6 p.

Research output: Contribution to journalArticle

Withholding Treatment
Smoking Cessation
Clinical Trials
Neoplasms
Counseling
1 Citation (Scopus)
Extracorporeal Membrane Oxygenation
Adult Respiratory Distress Syndrome
Intravenous Administration
Severe Acute Respiratory Syndrome
Water-Electrolyte Balance
13 Citations (Scopus)

Community-Acquired Pneumonia Visualized on CT Scans but Not Chest Radiographs: Pathogens, Severity, and Clinical Outcomes

Upchurch, C. P., Grijalva, C. G., Wunderink, R. G., Williams, D. J., Waterer, G. W., Anderson, E. J., Zhu, Y., Hart, E. M., Carroll, F., Bramley, A. M., Jain, S., Edwards, K. M. & Self, W. H., Mar 1 2018, In : CHEST. 153, 3, p. 601-610 10 p.

Research output: Contribution to journalArticle

Pneumonia
Thorax
Radiography
Length of Stay
Vital Signs
5 Citations (Scopus)

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy

Baida, G., Bhalla, P., Yemelyanov, A., Stechschulte, L. A., Shou, W., Readhead, B., Dudley, J. T., Sánchez, E. R. & Budunova, I., Oct 1 2018, In : Oncotarget. 9, 78, p. 34772-34783 12 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Glucocorticoid Receptors
Glucocorticoids
Atrophy
Skin
3 Citations (Scopus)

Dilution factor of quantitative bacterial cultures obtained by bronchoalveolar lavage in patients with ventilator-associated bacterial pneumonia

Drusano, G. L., Corrado, M. L., Girardi, G., Ellis-Grosse, E. J., Wunderink, R. G., Donnelly, H., Leeper, K. V., Brown, M., Malek, T., Hite, R. D., Ferrari, M., Djureinovic, D., Kollef, M. H., Mayfield, L., Doyle, A., Chastre, J., Combes, A., Walsh, T. J., Dorizas, K., Alnuaimat, H. & 13 others, Morgan, B. E., Rello, J., Torre, C. A. M., Jones, R. N., Flamm, R. K., Woosley, L., Ambrose, P. G., Bhavnani, S., Rubino, C. M., Bulik, C. C., Louie, A., Vicchiarelli, M. & Berman, C., Jan 1 2018, In : Antimicrobial agents and chemotherapy. 62, 1, e01323.

Research output: Contribution to journalArticle

Bacterial Pneumonia
Ventilator-Associated Pneumonia
Bronchoalveolar Lavage Fluid
Bronchoalveolar Lavage
Granulocytes
7 Citations (Scopus)

DNA methylation regulates the neonatal CD4 T-cell response to pneumonia in mice

McGrath-Morrow, S. A., Ndeh, R., Helmin, K. A., Chen, S. Y., Anekalla, K. R., Abdala-Valencia, H., D’Alessio, F. R., Michael Collaco, J. & Singer, B., Jan 1 2018, In : Journal of Biological Chemistry. 293, 30, p. 11772-11783 12 p.

Research output: Contribution to journalArticle

T-cells
DNA Methylation
Pneumonia
T-Lymphocytes
Pediatrics
Immunologic Memory
Acute Lung Injury
Transfer RNA
MicroRNAs
Human Influenza
4 Citations (Scopus)

E2F1 suppresses oxidative metabolism and endothelial differentiation of bone marrow progenitor cells

Xu, S., Tao, J., Yang, L., Zhang, E., Boriboun, C., Zhou, J., Sun, T., Cheng, M., Huang, K., Shi, J., Dong, N., Liu, Q., Zhao, T. C., Qiu, H., Harris, R. A., Chandel, N. S., Losordo, D. W. & Qin, G., Mar 1 2018, In : Circulation research. 122, 5, p. 701-711 11 p.

Research output: Contribution to journalArticle

E2F1 Transcription Factor
Bone Marrow Cells
Stem Cells
Cell- and Tissue-Based Therapy
Endothelial Cells
21 Citations (Scopus)

Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial

Wunderink, R. G., Giamarellos-Bourboulis, E. J., Rahav, G., Mathers, A. J., Bassetti, M., Vazquez, J., Cornely, O. A., Solomkin, J., Bhowmick, T., Bishara, J., Daikos, G. L., Felton, T., Furst, M. J. L., Kwak, E. J., Menichetti, F., Oren, I., Alexander, E. L., Griffith, D., Lomovskaya, O., Loutit, J. & 3 others, Zhang, S., Dudley, M. N. & Kaye, K. S., Dec 1 2018, In : Infectious Diseases and Therapy. 7, 4, p. 439-455 17 p.

Research output: Contribution to journalArticle

Enterobacteriaceae Infections
Carbapenems
Randomized Controlled Trials
Safety
Confidence Intervals
1 Citation (Scopus)

Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis of Breast Cancer Thoracic Metastases and Detection of Receptor Discordance

Argento, A. C., Gilstrap, D. L., Shofer, S., Mahmood, K., Blackwell, K. & Wahidi, M. M., Jul 1 2018, In : Journal of Bronchology and Interventional Pulmonology. 25, 3, p. 176-180 5 p.

Research output: Contribution to journalArticle

Needles
Thorax
Breast Neoplasms
Neoplasm Metastasis
Neoplasms

ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes

Wei, J., Yuan, Y., Chen, L., Xu, Y., Zhang, Y., Wang, Y., Yang, Y., Bien, C., Diebold, L., Yang, Y., Gao, B., Jin, C., Melo-Cardenas, J., Chandel, N., Zhang, D. D., Pan, H., Zhang, K., Wang, J., He, F. & Fang, D., Dec 1 2018, In : Nature communications. 9, 1, 3659.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl CoA Reductases
metabolism
Ligases
Ubiquitin
liver
9 Citations (Scopus)

Etiology and impact of coinfections in children hospitalized with community-acquired pneumonia

Nolan, V. G., Arnold, S. R., Bramley, A. M., Ampofo, K., Williams, D. J., Grijalva, C. G., Self, W. H., Anderson, E. J., Wunderink, R. G., Edwards, K. M., Pavia, A. T., Jain, S. & McCullers, J. A., Jun 20 2018, In : Journal of Infectious Diseases. 218, 2, p. 179-188 10 p.

Research output: Contribution to journalArticle

Hospitalized Child
Coinfection
Pneumonia
Viruses
Virus Diseases
4 Citations (Scopus)
Severe Acute Respiratory Syndrome
Extracorporeal Membrane Oxygenation
Adult Respiratory Distress Syndrome
Artificial Respiration
Vital Capacity
1 Citation (Scopus)

Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions

Ishiyama, N., Sarpal, R., Wood, M. N., Barrick, S. K., Nishikawa, T., Hayashi, H., Kobb, A. B., Flozak, A. S., Yemelyanov, A., Fernandez-Gonzalez, R., Yonemura, S., Leckband, D. E., Gottardi, C., Tepass, U. & Ikura, M., Dec 1 2018, In : Nature communications. 9, 1, 5121.

Research output: Contribution to journalArticle

Adherens Junctions
Catenins
Actins
helices
Cadherins
8 Citations (Scopus)

Future research directions in pneumonia

Dela Cruz, C. S., Wunderink, R. G., Christiani, D. C., Cormier, S. A., Crothers, K., Doerschuk, C. M., Evans, S. E., Goldstein, D. R., Khatri, P., Kobzik, L., Kolls, J. K., Levy, B. D., Metersky, M. L., Niederman, M. S., Nusrat, R., Orihuela, C. J., Peyrani, P., Prince, A. S., Ramírez, J. A., Ridge, K. M. & 9 others, Sethi, S., Suratt, B. T., Sznajder, J. I., Tsalik, E. L., Walkey, A. J., Yende, S., Aggarwal, N. R., Caler, E. V. & Mizgerd, J. P., Jul 15 2018, In : American journal of respiratory and critical care medicine. 198, 2, p. 256-263 8 p.

Research output: Contribution to journalArticle

Pneumonia
Lung
Direction compound
National Heart, Lung, and Blood Institute (U.S.)
Adult Respiratory Distress Syndrome
4 Citations (Scopus)

Harmonization of Respiratory Data from 9 US Population-Based Cohorts

Oelsner, E. C., Balte, P. P., Cassano, P. A., Couper, D., Enright, P. L., Folsom, A. R., Hankinson, J., Jacobs, D. R., Kalhan, R., Kaplan, R., Kronmal, R., Lange, L., Loehr, L. R., London, S. J., Acien, A. N., Newman, A. B., O'Connor, G. T., Schwartz, J. E., Smith, L. J., Yeh, F. & 6 others, Zhang, Y., Moran, A. E., Mwasongwe, S., White, W. B., Yende, S. & Barr, R. G., Nov 1 2018, In : American journal of epidemiology. 187, 11, p. 2265-2278 14 p.

Research output: Contribution to journalArticle

Population
Spirometry
Hispanic Americans
Hospitalization
National Heart, Lung, and Blood Institute (U.S.)

High exposure mining occupations are associated with obstructive lung disease, National Health Interview Survey (NHIS), 2006-2015

Mabila, S. L., Almberg, K. S., Friedman, L. & Cohen, R. A., Sep 1 2018, In : American Journal of Industrial Medicine. 61, 9, p. 715-724 10 p.

Research output: Contribution to journalArticle

Obstructive Lung Diseases
Health Surveys
Occupations
Interviews
Chronic Bronchitis
1 Citation (Scopus)
Hypercapnia
Nucleosomes
Lipid Metabolism
Epithelial Cells
Carbon Monoxide
1 Citation (Scopus)

Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling

Shigemura, M., Lecuona, E., Angulo, M., Homma, T., Rodríguez, D. A., Gonzalez-Gonzalez, F. J., Welch, L. C., Amarelle, L., Kim, S., Kaminski, N., Budinger, GR. S., Solway, J. & Sznajder, J. I., Sep 5 2018, In : Science Translational Medicine. 10, 457, aat1662.

Research output: Contribution to journalArticle

Caspase 7
Hypercapnia
MicroRNAs
Smooth Muscle
Chronic Obstructive Pulmonary Disease
1 Citation (Scopus)

Impact of Multiple Daily Clinical Pharmacist-Enforced Assessments on Time in Target Sedation Range

Lizza, B. D., Jagow, B., Hensler, D., Cooper, C. J., Short, E. J., Maas, M. B., Naidech, A. M. & Wunderink, R. G., Oct 1 2018, In : Journal of Pharmacy Practice. 31, 5, p. 445-449 5 p.

Research output: Contribution to journalArticle

Pharmacists
Artificial Respiration
Hypnotics and Sedatives
Fentanyl
Standard of Care
1 Citation (Scopus)

Inflammation and transcriptional responses of peripheral blood mononuclear cells in classic ataxia telangiectasia

McGrath-Morrow, S. A., Ndeh, R., Collaco, J. M., Rothblum-Oviatt, C., Wright, J., O’Reilly, M. A., Singer, B. & Lederman, H. M., Dec 1 2018, In : PloS one. 13, 12, e0209496.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
mononuclear leukocytes
Blood Cells
Blood
Genes
12 Citations (Scopus)

Inflammatory monocytes drive influenza A virus-mediated lung injury in juvenile mice

Coates, B. M., Staricha, K. L., Koch, C. M., Cheng, Y., Shumaker, D. K., Budinger, G. R. S., Perlman, H., Misharin, A. V. & Ridge, K. M., Apr 1 2018, In : Journal of Immunology. 200, 7, p. 2391-2404 14 p.

Research output: Contribution to journalArticle

Influenza A virus
Lung Injury
Human Influenza
Monocytes
Inflammasomes

Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis

Sala, M. A., Balderas-Martínez, Y. I., Buendía-Roldan, I., Abdala-Valencia, H., Nam, K., Jain, M., Bhorade, S. M., Bharat, A., Reyfman, P. A., Ridge, K. M., Pardo, A., Sznajder, J. I., Budinger, GR. S., Misharin, A. & Selman, M., Nov 26 2018, In : Respiratory Research. 19, 1, 233.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Nasal Mucosa
Nose
Up-Regulation
RNA Sequence Analysis
11 Citations (Scopus)

Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome

Mutlu, E. A., Comba, I. Y., Cho, T., Engen, P. A., Yazıcı, C., Soberanes, S., Hamanaka, R. B., Niğdelioğlu, R., Meliton, A. Y., Ghio, A. J., Budinger, GR. S. & Mutlu, G. M., Sep 1 2018, In : Environmental pollution (Barking, Essex : 1987). 240, p. 817-830 14 p.

Research output: Contribution to journalArticle

Particulate Matter
Air Pollution
Air pollution
Gastrointestinal Tract
Air
3 Citations (Scopus)

In-Hospital Deaths Among Adults With Community-Acquired Pneumonia

Waterer, G. W., Self, W. H., Courtney, D. M., Grijalva, C. G., Balk, R. A., Girard, T. D., Fakhran, S. S., Trabue, C., McNabb, P., Anderson, E. J., Williams, D. J., Bramley, A. M., Jain, S., Edwards, K. M. & Wunderink, R. G., Sep 1 2018, In : CHEST. 154, 3, p. 628-635 8 p.

Research output: Contribution to journalArticle

Pneumonia
Cause of Death
Quality of Health Care
Tertiary Healthcare
Tertiary Care Centers
1 Citation (Scopus)

Invasive Mechanical Ventilation

Walter, J. M., Corbridge, T. C. & Singer, B., Dec 1 2018, In : Southern Medical Journal. 111, 12, p. 746-753 8 p.

Research output: Contribution to journalArticle

Artificial Respiration
Respiratory Mechanics
Positive-Pressure Respiration
Mechanical Ventilators
Respiratory System
4 Citations (Scopus)

JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension

Sala, M. A., Chen, C., Zhang, Q., Do-Umehara, H. C., Wu, W., Misharin, A. V., Waypa, G. B., Fang, D., Budinger, G. R. S., Liu, S., Chandel, N. S., Schumacker, P. T., Sznajder, J. I. & Liu, J., Jan 1 2018, In : Journal of Biological Chemistry. 293, 1, p. 271-284 14 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Erythropoiesis
Pulmonary Hypertension
Up-Regulation
Protein Kinases
5 Citations (Scopus)

Knowledge gaps in the perioperative management of adults with obstructive sleep apnea and obesity hypoventilation syndrome an official American Thoracic society workshop report

Ayas, N. T., Laratta, C. R., Coleman III, J. M., Doufas, A. G., Eikermann, M., Gay, P. C., Gottlieb, D. J., Gurubhagavatula, I., Hillman, D. R., Kaw, R., Malhotra, A., Mokhlesi, B., Morgenthaler, T. I., Parthasarathy, S., Ramachandran, S. K., Strohl, K. P., Strollo, P. J., Twery, M. J., Zee, P. C. & Chung, F. F., Feb 1 2018, In : Annals of the American Thoracic Society. 15, 2, p. 117-126 10 p.

Research output: Contribution to journalArticle

Obesity Hypoventilation Syndrome
Obstructive Sleep Apnea
Thorax
Education
Sleep
8 Citations (Scopus)

Lumacaftor/ivacaftor in patients with cystic fibrosis and advanced lung disease homozygous for F508del-CFTR

VX14-809-106 Investigator Group, Mar 1 2018, In : Journal of Cystic Fibrosis. 17, 2, p. 228-235 8 p.

Research output: Contribution to journalArticle

Cystic Fibrosis
Lung Diseases
Forced Expiratory Volume
Safety
ivacaftor drug combination lumacaftor

Lung function in young adults and risk of cardiovascular events over 29 years: The CARDIA study

Cuttica, M. J., Colangelo, L. A., Dransfield, M. T., Bhatt, S. P., Rana, J. S., Jacobs, D. R., Thyagarajan, B., Sidney, S., Lewis, C. E., Liu, K., Lloyd-Jones, D. M., Washko, G. & Kalhan, R., Dec 1 2018, In : Journal of the American Heart Association. 7, 24, e010672.

Research output: Contribution to journalArticle

Young Adult
Lung
Forced Expiratory Volume
Coronary Vessels
Cardiovascular Diseases

Matrix protein tenascin-C expands and reversibly blocks maturation of murine eosinophil progenitors

Doan, T. C., Jeong, B. M., Coden, M. E., Loffredo, L. F., Bhattacharyya, S., Chiarella, S. E., Varga, J., Abdala-Valencia, H. & Berdnikovs, S., Aug 1 2018, In : Journal of Allergy and Clinical Immunology. 142, 2, p. 695-698.e4

Research output: Contribution to journalArticle

Tenascin
Protein C
Eosinophils
1 Citation (Scopus)

Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum Vitamin D with pulmonary function

Xu, J., Bartz, T. M., Chittoor, G., Eiriksdottir, G., Manichaikul, A. W., Sun, F., Terzikhan, N., Zhou, X., Booth, S. L., Brusselle, G. G., De Boer, I. H., Fornage, M., Frazier-Wood, A. C., Graff, M., Gudnason, V., Harris, T. B., Hofman, A., Hou, R., Houston, D. K., Jacobs, D. R. & 26 others, Kritchevsky, S. B., Latourelle, J., Lemaitre, R. N., Lutsey, P. L., O'Connor, G., Oelsner, E. C., Pankow, J. S., Psaty, B. M., Rohde, R. R., Rich, S. S., Rotter, J. I., Smith, L. J., Stricker, B. H., Voruganti, V. S., Wang, T. J., Zillikens, M. C., Barr, R. G., Dupuis, J., Gharib, S. A., Lahousse, L., London, S. J., North, K. E., Smith, A. V., Steffen, L. M., Hancock, D. B. & Cassano, P. A., Nov 28 2018, In : British Journal of Nutrition. 120, 10, p. 1159-1170 12 p.

Research output: Contribution to journalArticle

Vital Capacity
Vitamin D
Meta-Analysis
Epidemiology
Lung
1 Citation (Scopus)

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis

Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C-I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 others, Jain, M., Perlman, H., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N. S., Mutlu, G. M. & Budinger, G. R. S., Oct 11 2018, In : Cell Metabolism.

Research output: Contribution to journalArticle

Metformin
Air Pollution
Electron Transport
Particulate Matter
Alveolar Macrophages
2 Citations (Scopus)

Mine Safety and Health Administration's Part 50 program does not fully capture chronic disease and injury in the Illinois mining industry

Almberg, K. S., Friedman, L. S., Swedler, D. & Cohen, R. A., May 1 2018, In : American Journal of Industrial Medicine. 61, 5, p. 436-443 8 p.

Research output: Contribution to journalArticle

Workers' Compensation
Industry
Chronic Disease
Safety
Health
7 Citations (Scopus)

Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells

Naguib, A., Mathew, G., Reczek, C. R., Watrud, K., Ambrico, A., Herzka, T., Salas, I. C., Lee, M. F., El-Amine, N., Zheng, W., Di Francesco, M. E., Marszalek, J. R., Pappin, D. J., Chandel, N. & Trotman, L. C., Apr 3 2018, In : Cell reports. 23, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

Null Lymphocytes
Prostatic Neoplasms
Cells
Blueprints
Mitochondria
9 Citations (Scopus)

Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation

Lozoya, O. A., Martinez-Reyes, I., Wang, T., Grenet, D., Bushel, P., Li, J., Chandel, N., Woychik, R. P. & Santos, J. H., Apr 18 2018, In : PLoS biology. 16, 4, e2005707.

Research output: Contribution to journalArticle

Citric Acid Cycle
tricarboxylic acid cycle
NAD (coenzyme)
DNA methylation
DNA Methylation
54 Citations (Scopus)

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmüller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bønnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., Burchard, E. & 155 others, Burkart, K. M., Bush, A., Chan-Yeung, M., Chung, K. F., Couto Alves, A., Curtin, J. A., Custovic, A., Daley, D., De Jongste, J. C., Del-Rio-Navarro, B. E., Donohue, K. M., Duijts, L., Eng, C., Eriksson, J. G., Farrall, M., Fedorova, Y., Feenstra, B., Ferreira, M. A., Freidin, M. B., Gajdos, Z., Gauderman, J., Gehring, U., Geller, F., Genuneit, J., Gharib, S. A., Gilliland, F., Granell, R., Graves, P. E., Gudbjartsson, D. F., Haahtela, T., Heckbert, S. R., Heederik, D., Heinrich, J., Heliövaara, M., Henderson, J., Himes, B. E., Hirose, H., Hirschhorn, J. N., Hofman, A., Holt, P., Hottenga, J., Hudson, T. J., Hui, J., Imboden, M., Ivanov, V., Jaddoe, V. W. V., James, A., Janson, C., Jarvelin, M. R., Jarvis, D., Jones, G., Jonsdottir, I., Jousilahti, P., Kabesch, M., Kähönen, M., Kantor, D. B., Karunas, A. S., Khusnutdinova, E., Koppelman, G. H., Kozyrskyj, A. L., Kreiner, E., Kubo, M., Kumar, R., Kumar, A., Kuokkanen, M., Lahousse, L., Laitinen, T., Laprise, C., Lathrop, M., Lau, S., Lee, Y. A., Lehtimäki, T., Letort, S., Levin, A. M., Li, G., Liang, L., Loehr, L. R., London, S. J., Loth, D. W., Manichaikul, A., Marenholz, I., Martinez, F. J., Matheson, M. C., Mathias, R. A., Matsumoto, K., Mbarek, H., McArdle, W. L., Melbye, M., Melén, E., Meyers, D., Michel, S., Mohamdi, H., Musk, A. W., Myers, R. A., Nieuwenhuis, M. A. E., Noguchi, E., O'Connor, G. T., Ogorodova, L. M., Palmer, C. D., Palotie, A., Park, J. E., Pennell, C. E., Pershagen, G., Polonikov, A., Postma, D. S., Probst-Hensch, N., Puzyrev, V. P., Raby, B. A., Raitakari, O. T., Ramasamy, A., Rich, S. S., Robertson, C. F., Romieu, I., Salam, M. T., Salomaa, V., Schlünssen, V., Scott, R., Selivanova, P. A., Sigsgaard, T., Simpson, A., Siroux, V., Smith, L. J., Solodilova, M., Standl, M., Stefansson, K., Strachan, D. P., Stricker, B. H., Takahashi, A., Thompson, P. J., Thorleifsson, G., Thorsteinsdottir, U., Tiesler, C. M. T., Torgerson, D. G., Tsunoda, T., Uitterlinden, A. G., Van Der Valk, R. J. P., Vaysse, A., Vedantam, S., Von Berg, A., Von Mutius, E., Vonk, J. M., Waage, J., Wareham, N. J., Weiss, S. T., White, W. B., Wickman, M., Widén, E., Willemsen, G., Williams, L. K., Wouters, I. M., Yang, J. J., Zhao, J. H., Moffatt, M. F., Ober, C. & Nicolae, D. L., Jan 1 2018, In : Nature Genetics. 50, 1, p. 42-50 9 p.

Research output: Contribution to journalArticle

Asthma
Seasonal Allergic Rhinitis
Genome-Wide Association Study
Autoimmune Diseases
Meta-Analysis

Multidimensional assessment of alveolar T cells in critically ill patients

Walter, J. M., Helmin, K. A., Abdala-Valencia, H., Wunderink, R. G. & Singer, B. D., Sep 6 2018, In : JCI Insight. 3, 17

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Critical Illness
Pneumonia
T-Lymphocytes
RNA Sequence Analysis
3 Citations (Scopus)

Multidimensional assessment of alveolar T cells in critically ill patients

Walter, J. M., Helmin, K. A., Abdala-Valencia, H., Wunderink, R. G. & Singer, B., Sep 6 2018, In : JCI insight. 3, 17

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Critical Illness
Pneumonia
T-Lymphocytes
RNA Sequence Analysis
5 Citations (Scopus)

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X. Q., Noordam, R., Hartwig, F. P. & 82 others, Jackson, V. E., Wang, T., Obeidat, M., Hobbs, B. D., Huan, T., Gui, H., Parker, M. M., Hu, D., Mogil, L. S., Kichaev, G., Jin, J., Graff, M., Harris, T. B., Kalhan, R., Heckbert, S. R., Paternoster, L., Burkart, K. M., Liu, Y., Holliday, E. G., Wilson, J. G., Vonk, J. M., Sanders, J. L., Barr, R. G., de Mutsert, R., Menezes, A. M. B., Adams, H. H. H., van den Berge, M., Joehanes, R., Levin, A. M., Liberto, J., Launer, L. J., Morrison, A. C., Sitlani, C. M., Celedón, J. C., Kritchevsky, S. B., Scott, R. J., Christensen, K., Rotter, J. I., Bonten, T. N., Wehrmeister, F. C., Bossé, Y., Xiao, S., Oh, S., Franceschini, N., Brody, J. A., Kaplan, R. C., Lohman, K., McEvoy, M., Province, M. A., Rosendaal, F. R., Taylor, K. D., Nickle, D. C., Williams, L. K., Burchard, E. G., Wheeler, H. E., Sin, D. D., Gudnason, V., North, K. E., Fornage, M., Psaty, B. M., Myers, R. H., O’Connor, G., Hansen, T., Laurie, C. C., Cassano, P. A., Sung, J., Kim, W. J., Attia, J. R., Lange, L., Boezen, H. M., Thyagarajan, B., Rich, S. S., Mook-Kanamori, D. O., Horta, B. L., Uitterlinden, A. G., Im, H. K., Cho, M. H., Brusselle, G. G., Gharib, S. A., Dupuis, J., Manichaikul, A. & London, S. J., Dec 1 2018, In : Nature communications. 9, 1, 2976.

Research output: Contribution to journalArticle

Open Access
pulmonary functions
loci
Meta-Analysis
genome
Genes
1 Citation (Scopus)

Occupational emphysema in South African miners at autopsy; 1975–2014

Mabila, S. L., Almberg, K. S., Friedman, L., Cohen, R., Ndlovu, N., Vorajee, N. & Murray, J., Nov 1 2018, In : International Archives of Occupational and Environmental Health. 91, 8, p. 981-990 10 p.

Research output: Contribution to journalArticle

Emphysema
Autopsy
Smoking
Automation
Logistic Models
2 Citations (Scopus)

Performance of forced vital capacity and lung diffusion cutpoints for associated radiographic interstitial lung disease in systemic sclerosis

Showalter, K., Hoffmann, A., Rouleau, G., Aaby, D., Lee, J., Richardson, C., Dematte D'Amico, J. E., Agrawal, R., Chang, R. W. & Hinchcliff, M., Nov 1 2018, In : Journal of Rheumatology. 45, 11, p. 1572-1576 5 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Interstitial Lung Diseases
Vital Capacity
Lung
Autoantibodies