Medicine, Pulmonary Division

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2013

Bronchoalveolar lavage amylase is associated with risk factors for aspiration and predicts bacterial pneumonia

Weiss, C. H., Moazed, F., Dibardino, D., Swaroop, M. & Wunderink, R. G., Mar 1 2013, In : Critical Care Medicine. 41, 3, p. 765-773 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

CAPE suppresses VEGFR-2 activation, and tumor neovascularization and growth

Chung, T. W., Kim, S. J., Choi, H. J., Kwak, C. H., Song, K. H., Suh, S. J., Kim, K. J., Ha, K. T., Park, Y. G., Chang, Y. C., Chang, H. W., Lee, Y. C. & Kim, C. H., Feb 1 2013, In : Journal of Molecular Medicine. 91, 2, p. 271-282 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

Bien, C., Affinati, A. H., Ramsey, K. M., Kuo, H. Y., Yu, W., Sena, L. A., Ilkayeva, O., Marcheva, B., Kobayashi, Y., Omura, C., Levine, D. C., Bacsik, D. J., Gius, D. R., Newgard, C. B., Goetzman, E., Chandel, N., Denu, J. M., Mrksich, M. & Bass, J., Jan 1 2013, In : Science. 342, 6158, 1243417.

Research output: Contribution to journalArticle

329 Scopus citations

Clinical risk factors for primary graft dysfunction after lung transplantation

Diamond, J. M., Lee, J. C., Kawut, S. M., Shah, R. J., Localio, A. R., Bellamy, S. L., Lederer, D. J., Cantu, E., Kohl, B. A., Lama, V. N., Bhorade, S. M., Crespo, M., Demissie, E., Sonett, J., Wille, K., Orens, J., Shah, A. S., Weinacker, A., Arcasoy, S., Shah, P. D. & 4 others, Wilkes, D. S., Ware, L. B., Palmer, S. M. & Christie, J. D., Mar 1 2013, In : American journal of respiratory and critical care medicine. 187, 5, p. 527-534 8 p.

Research output: Contribution to journalArticle

275 Scopus citations

Combination of a selective activator of the glucocorticoid receptor Compound A with a proteasome inhibitor as a novel strategy for chemotherapy of hematologic malignancies

Lesovaya, E., Yemelyanov, A., Kirsanov, K., Popa, A., Belitsky, G., Yakubovskaya, M., Gordon, L. I., Rosen, S. T. & Budunova, I., Jan 1 2013, In : Cell Cycle. 12, 1, p. 133-144 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Critical Role of Endothelial Hydrogen Peroxide in Post-Ischemic Neovascularization

Urao, N., Sudhahar, V., Kim, S. J., Chen, G. F., McKinney, R. D., Kojda, G., Fukai, T. & Ushio-Fukai, M., Mar 5 2013, In : PloS one. 8, 3, e57618.

Research output: Contribution to journalArticle

28 Scopus citations

Decreased incidence of cytomegalovirus infection with sirolimus in a post hoc randomized, multicenter study in lung transplantation

Ghassemieh, B., Ahya, V. N., Baz, M. A., Valentine, V. G., Arcasoy, S. M., Love, R. B., Seethamraju, H., Alex, C. G., Bag, R., Deoliveira, N. C., Vigneswaran, W. T., Charbeneau, J., Garrity, E. R. & Bhorade, S. M., Jul 1 2013, In : Journal of Heart and Lung Transplantation. 32, 7, p. 701-706 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Development of a highly sensitive three-dimensional gel electrophoresis method for characterization of monoclonal protein heterogeneity

Nakano, K., Tamura, S., Otuka, K., Niizeki, N., Shigemura, M., Shimizu, C., Matsuno, K., Kobayashi, S. & Moriyama, T., Jul 15 2013, In : Analytical Biochemistry. 438, 2, p. 117-123 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Early initiation of prostacyclin in portopulmonary hypertension: 10 Years of a transplant center's experience

Awdish, R. L. A. & Cajigas, H. R., Dec 1 2013, In : Lung. 191, 6, p. 593-600 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effect of extended-release niacin on serum lipids and on endothelial function in adults with sickle cell anemia and low high-density lipoprotein cholesterol levels

Scoffone, H. M., Krajewski, M., Zorca, S., Bereal-Williams, C., Littel, P., Seamon, C., Mendelsohn, L., Footman, E., Abi-Jaoudeh, N., Sachdev, V., Machado, R. F., Cuttica, M., Shamburek, R., Cannon, R. O., Remaley, A., Minniti, C. P. & Kato, G. J., Nov 1 2013, In : American Journal of Cardiology. 112, 9, p. 1499-1504 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Endobronchial ultrasound when to venture into the vasculature

Al-Ajam, M. R., Kalanjeri, S., Haas, A. R., Gillespie, C. T. & Sterman, D. H., Aug 1 2013, In : Annals of the American Thoracic Society. 10, 4, p. 393-395 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
17 Scopus citations

Epidemiology and long-term clinical and biologic risk factors for pneumonia in community-dwelling older Americans analysis of three cohorts

Yende, S., Alvarez, K., Loehr, L., Folsom, A. R., Newman, A. B., Weissfeld, L. A., Wunderink, R. G., Kritchevsky, S. B., Mukamal, K. J., London, S. J., Harris, T. B., Bauer, D. C. & Angus, D. C., Jan 1 2013, In : Chest. 144, 3, p. 1008-1017 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Etiologies of bilateral pleural effusions

Puchalski, J. T., Argento, A. C., Murphy, T. E., Araujo, K. L. B., Oliva, I. B., Rubinowitz, A. N. & Pisani, M. A., Feb 1 2013, In : Respiratory Medicine. 107, 2, p. 284-291 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K. W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., Hume, D. A., Perlman, H., Malissen, B., Zelzer, E. & Jung, S., Jan 24 2013, In : Immunity. 38, 1, p. 79-91 13 p.

Research output: Contribution to journalArticle

1196 Scopus citations
23 Scopus citations

Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung

Misharin, A. V., Morales-Nebreda, L., Mutlu, G. M., Budinger, G. R. S. & Perlman, H., Oct 1 2013, In : American journal of respiratory cell and molecular biology. 49, 4, p. 503-510 8 p.

Research output: Contribution to journalArticle

296 Scopus citations

Ganglioside GM3 participates in the TGF-β1-induced epithelial-mesenchymal transition of human lens epithelial cells

Kim, S. J., Chung, T. W., Choi, H. J., Kwak, C. H., Song, K. H., Suh, S. J., Kwon, K. M., Chang, Y. C., Park, Y. G., Chang, H. W., Kim, K. S., Kim, C. H. & Lee, Y. C., Jan 1 2013, In : Biochemical Journal. 449, 1, p. 241-251 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
35 Scopus citations

Hemodynamic predictors of mortality in adults with sickle cell disease

Mehari, A., Alam, S., Tian, X., Cuttica, M. J., Barnett, C. F., Miles, G., Xu, D., Seamon, C., Adams-Graves, P., Castro, O. L., Minniti, C. P., Sachdev, V., Taylor VI, J. G., Kato, G. J. & Machado, R. F., Apr 15 2013, In : American journal of respiratory and critical care medicine. 187, 8, p. 840-847 8 p.

Research output: Contribution to journalArticle

71 Scopus citations

Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

Patra, K. C., Wang, Q., Bhaskar, P. T., Miller, L., Wang, Z., Wheaton, W., Chandel, N., Laakso, M., Muller, W. J., Allen, E. L., Jha, A. K., Smolen, G. A., Clasquin, M. F., Robey, R. B. & Hay, N., Aug 12 2013, In : Cancer Cell. 24, 2, p. 213-228 16 p.

Research output: Contribution to journalArticle

334 Scopus citations

High burden of palliative needs among older intensive care unit survivors transferred to post-Acute care facilities

Baldwin, M. R., Wunsch, H., Reyfman, P. A., Narain, W. R., Blinderman, C. D., Schluger, N. W., Reid, M. C., Maurer, M. S., Goldstein, N., Lederer, D. J. & Bach, P., Oct 1 2013, In : Annals of the American Thoracic Society. 10, 5, p. 458-465 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

High discordance of chest x-ray and computed tomography for detection of pulmonary opacities in ED patients: Implications for diagnosing pneumonia

Self, W. H., Courtney, D. M., McNaughton, C. D., Wunderink, R. G. & Kline, J. A., Feb 1 2013, In : American Journal of Emergency Medicine. 31, 2, p. 401-405 5 p.

Research output: Contribution to journalArticle

102 Scopus citations
4 Scopus citations

Hypercapnia impairs lung neutrophil function and increases mortality in murine Pseudomonas pneumonia

Gates, K. L., Howell, H. A., Nair, A., Vohwinkel, C. U., Welch, L. C., Beitel, G. J., Hauser, A. R., Sznajder, J. I. & Sporn, P. H. S., Nov 1 2013, In : American journal of respiratory cell and molecular biology. 49, 5, p. 821-828 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours

Campos, M. L., Sánchez-Arévalo Lobo, V. J., Rodolosse, A., Gottardi, C., Mafficini, A., Beghelli, S., Scardoni, M., Bassi, C., Scarpa, A. & Real, F. X., May 1 2013, In : Biochemical Journal. 451, 3, p. 395-405 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Implementing team-based learning in a nurse practitioner curriculum

Corbridge, S. J., Corbridge, T. C., Tiffen, J. & Carlucci, M., Jan 1 2013, In : Nurse Educator. 38, 5, p. 202-205 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation

Yan, J., Xiang, J., Lin, Y., Ma, J., Zhang, J., Zhang, H., Sun, J., Danial, N. N., Liu, J. & Lin, A., Jan 7 2013, In : Cell. 152, 1-2, p. 304-315 12 p.

Research output: Contribution to journalArticle

59 Scopus citations

Interobserver variability in grading transbronchial lung biopsy specimens after lung transplantation

Bhorade, S. M., Husain, A. N., Liao, C., Li, L. C., Ahya, V. N., Baz, M. A., Valentine, V. G., Love, R. B., Seethamraju, H., Alex, C. G., Bag, R., DeOliveira, N. C., Vigneswaran, W. T., Garrity, E. R. & Arcasoy, S. M., Jun 2013, In : CHEST. 143, 6, p. 1717-1724 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Laminin-332 and α3β1 integrin-supported migration of bronchial epithelial cells is modulated by fibronectin

Kligys, K., Wu, Y., Hamill, K. J., Lewandowski, K. T., Hopkinson, S. B., Budinger, G. R. S. & Jones, J. C. R., Nov 1 2013, In : American journal of respiratory cell and molecular biology. 49, 5, p. 731-740 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation

Shah, R. J., Diamond, J. M., Cantu, E., Lee, J. C., Lederer, D. J., Lama, V. N., Orens, J., Weinacker, A., Wilkes, D. S., Bhorade, S., Wille, K. M., Ware, L. B., Palmer, S. M., Crespo, M., Localio, A. R., Demissie, E., Kawut, S. M., Bellamy, S. L. & Christie, J. D., Jan 1 2013, In : CHEST. 144, 2, p. 616-622 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Leflunomide-induced interstitial lung disease (a systematic review)

Raj, R. & Nugent, K., Jan 1 2013, In : Sarcoidosis Vasculitis and Diffuse Lung Diseases. 30, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Leflunomide-induced interstitial lung disease (a systematic review). PMID: 24284289

Raj, R. & Nugent, K., Nov 2013, In : Sarcoidosis Vasc Diffuse Lung Dis. 30, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

Linezolid Exerts Greater Bacterial Clearance but No Modification of Host Lung Gene Expression Profiling: A Mouse MRSA Pneumonia Model

Chen, J., Feng, G., Song, Y., Wardenburg, J. B., Lin, S., Inoshima, I., Otto, M. & Wunderink, R. G., Jun 27 2013, In : PloS one. 8, 6, e67994.

Research output: Contribution to journalArticle

2 Scopus citations

Matrix metalloproteinase (MMP)-1 induces lung alveolar epithelial cell migration and proliferation, protects from apoptosis, and represses mitochondrial oxygen consumption

Herrera, I., Cisneros, J., Maldonado, M., Ramírez, R., Ortiz-Quintero, B., Anso, E., Chandel, N. S., Selman, M. & Pardo, A., Sep 6 2013, In : Journal of Biological Chemistry. 288, 36, p. 25964-25975 12 p.

Research output: Contribution to journalArticle

52 Scopus citations

Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching

Bothmer, A., Rommel, P. C., Gazumyan, A., Polato, F., Reczek, C. R., Muellenbeck, M. F., Schaetzlein, S., Edelmann, W., Chen, P. L., Brosh, R. M., Casellas, R., Ludwig, T., Baer, R., Nussenzweig, A., Nussenzweig, M. C. & Robbiani, D. F., Jan 1 2013, In : Journal of Experimental Medicine. 210, 1, p. 115-123 9 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

Sena, L. A., Li, S., Jairaman, A., Prakriya, M., Ezponda, T., Hildeman, D. A., Wang, C. R., Schumacker, P. T., Licht, J. D., Perlman, H., Bryce, P. J. & Chandel, N. S., Feb 21 2013, In : Immunity. 38, 2, p. 225-236 12 p.

Research output: Contribution to journalArticle

440 Scopus citations

Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development

Hamanaka, R. B., Glasauer, A., Hoover, P., Yang, S., Blatt, H., Mullen, A. R., Getsios, S., Gottardi, C. J., DeBerardinis, R. J., Lavker, R. M. & Chandel, N. S., Feb 5 2013, In : Science Signaling. 6, 261, ra8.

Research output: Contribution to journalArticle

161 Scopus citations

Mitochondrial reactive oxygen species regulate transforming growth factor-β signaling

Jain, M., Rivera, S., Monclus, E. A., Synenki, L., Zirk, A., Eisenbart, J., Feghali-Bostwick, C., Mutlu, G. M., Budinger, GR. S. & Chandel, N., Jan 11 2013, In : Journal of Biological Chemistry. 288, 2, p. 770-777 8 p.

Research output: Contribution to journalArticle

163 Scopus citations

Molecular Adsorbent Recirculating System (MARS®) removal of piperacillin/tazobactam in a patient with acetaminophen-induced acute liver failure

Ruggero, M. A., Argento, A. C., Heavner, M. S. & Topal, J. E., Apr 1 2013, In : Transplant Infectious Disease. 15, 2, p. 214-218 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

National burden of antibiotic use for adult rhinosinusitis

Smith, S. S., Evans, C. T., Tan, B. K., Chandra, R. K., Smith, S. B. & Kern, R. C., Nov 2013, In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1230-1232 3 p.

Research output: Contribution to journalArticle

55 Scopus citations

Oropharyngeal flora in patients admitted to the medical intensive care unit: Clinical factors and acid suppressive therapy

Nugent, K., Frandah, W., Colmer-Hamood, J., Amiri, H. M. & Raj, R., May 1 2013, In : Journal of Medical Microbiology. 62, PART5, p. 778-784 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth

Ono, M., Yin, P., Navarro, A., Moravek, M. B., Coon V, J. S., Druschitz, S. A., Serna, V. A., Qiang, W., Brooks, D. C., Malpani, S. S., Ma, J., Ercan, C. M., Mittal, N., Monsivais, D., Dyson, M. T., Yemelyanov, A., Maruyama, T., Chakravarti, D., Kim, J. J., Kurita, T. & 2 others, Gottardi, C. J. & Bulun, S. E., Oct 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 17053-17058 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Plectin-containing, centrally localized focal adhesions exert traction forces in primary lung epithelial cells

Eisenberg, J. L., Beaumont, K. G., Takawira, D., Hopkinson, S. B., Mrksich, M., Scott Budinger, G. R. & Jones, J. C. R., Sep 9 2013, In : Journal of cell science. 126, 16, p. 3746-3755 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Prediction of advanced fibrosis in nonalcoholic fatty liver disease: An enhanced model of BARD score

Lee, T. H., Han, S., Yang, J. D., Kim, D. & Ahmed, M., May 1 2013, In : Gut and Liver. 7, 3, p. 323-328 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Protein kinase A-Iα regulates Na,K-ATPase endocytosis in alveolar epithelial cells exposed to high CO2 concentrations

Lecuona, E., Sun, H., Chen, J., Trejo, H. E., Baker, M. A. & Sznajder, J. I., May 1 2013, In : American journal of respiratory cell and molecular biology. 48, 5, p. 626-634 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Pulmonary hyperinflation and left ventricular mass: The multi-ethnic study of atherosclerosis COPD study

Smith, B. M., Kawut, S. M., Bluemke, D. A., Basner, R. C., Gomes, A. S., Hoffman, E., Kalhan, R., Lima, J. A. C., Liu, C. Y., Michos, E. D., Prince, M. R., Rabbani, L., Rabinowitz, D., Shimbo, D., Shea, S. & Barr, R. G., Apr 9 2013, In : Circulation. 127, 14, p. 1503-1511 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Pulmonary manifestations of anti-ARS antibody positive interstitial pneumonia-With or without PM/DM

Takato, H., Waseda, Y., Watanabe, S., Inuzuka, K., Katayama, N., Ichikawa, Y., Yasui, M. & Fujimura, M., Jan 1 2013, In : Respiratory Medicine. 107, 1, p. 128-133 6 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Replication and fine mapping of asthma-associated loci in individuals of African ancestry

Kantor, D. B., Palmer, C. D., Young, T. R., Meng, Y., Gajdos, Z. K., Lyon, H., Price, A. L., Pollack, S., London, S. J., Loehr, L. R., Smith, L. J., Kumar, R., Jacobs, D. R., Petrini, M. F., O'Connor, G. T., White, W. B., Papanicolaou, G., Burkart, K. M., Heckbert, S. R., Barr, R. G. & 1 others, Hirschhorn, J. N., Sep 1 2013, In : Human Genetics. 132, 9, p. 1039-1047 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Sequestration of mitochondrial iron by silica particle initiates a biological effect

Ghio, A. J., Tong, H., Soukup, J. M., Dailey, L. A., Cheng, W. Y., Samet, J. M., Kesic, M. J., Bromberg, P. A., Turi, J. L., Upadhyay, D., Scott Budinger, G. R. & Mutlu, G. M., Nov 15 2013, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 305, 10, p. L712-L724

Research output: Contribution to journalArticle

20 Scopus citations