Medicine, Pulmonary Division

Research Output 1949 2019

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2011
39 Citations (Scopus)

Light-induced changes of the circadian clock of humans: Increasing duration is more effective than increasing light intensity

Dewan, K., Benloucif, S., Reid, K. J., Wolfe, L. F. & Zee, P. C., May 1 2011, In : Sleep. 34, 5, p. 593-599 7 p.

Research output: Contribution to journalArticle

Circadian Clocks
Light
Melatonin
Circadian Rhythm
Circadian Rhythm Sleep Disorders
44 Citations (Scopus)

Localized cysteine sulfenic acid formation by vascular endothelial growth factor: Role in endothelial cell migration and angiogenesis

Kaplan, N., Urao, N., Furuta, E., Kim, S. J., Razvi, M., Nakamura, Y., McKinney, R. D., Poole, L. B., Fukai, T. & Ushio-Fukai, M., Oct 1 2011, In : Free Radical Research. 45, 10, p. 1124-1135 12 p.

Research output: Contribution to journalArticle

Endothelial cells
Vascular Endothelial Growth Factor A
Cell Movement
Endothelial Cells
Vascular Endothelial Growth Factor Receptor
19 Citations (Scopus)

Lung-specific loss of the laminin α3 subunit confers resistance to mechanical injury

Urich, D., Eisenberg, J. L., Hamill, K. J., Takawira, D., Chiarella, S. E., Soberanes, S., Gonzalez, A., Koentgen, F., Manghi, T., Hopkinson, S. B., Misharin, A., Perlman, H. R., Mutlu, G. M., Budinger, GR. S. & Jones, J. C. R., Sep 1 2011, In : Journal of cell science. 124, 17, p. 2927-2937 11 p.

Research output: Contribution to journalArticle

Laminin
Lung
Wounds and Injuries
Basement Membrane
Collagen
33 Citations (Scopus)
Chemokine CCL2
Up-Regulation
Epithelium
Mucins
CCR2 Receptors
12 Citations (Scopus)

MDCT bolus tracking data as an adjunct for predicting the diagnosis of pulmonary hypertension and concomitant right-heart failure

Davarpanah, A. H., Hodnett, P. A., Farrelly, C. T., Shah, S. J., Cuttica, M. J., Ragin, A. B., Carr, J. & Yaghmai, V., Nov 1 2011, In : American Journal of Roentgenology. 197, 5, p. 1064-1072 9 p.

Research output: Contribution to journalArticle

Right Ventricular Dysfunction
Pulmonary Hypertension
Heart Failure
Pulmonary Artery
Lung
13 Citations (Scopus)

Mechanisms for vascular cell adhesion molecule-1 activation of ERK1/2 during leukocyte transendothelial migration

Abdala-Valencia, H., Berdnikovs, S. & Cook-Mills, J. M., Oct 27 2011, In : PLoS One. 6, 10, e26706.

Research output: Contribution to journalArticle

Transendothelial and Transepithelial Migration
Vascular Cell Adhesion Molecule-1
cell adhesion
blood vessels
leukocytes
325 Citations (Scopus)

Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung

Duch, M. C., Budinger, GR. S., Liang, Y. T., Soberanes, S., Urich, D., Chiarella, S. E., Campochiaro, L. A., Gonzalez, A., Chandel, N., Hersam, M. & Mutlu, G. M., Dec 14 2011, In : Nano letters. 11, 12, p. 5201-5207 7 p.

Research output: Contribution to journalArticle

Graphite
biocompatibility
Biocompatibility
lungs
Graphene
320 Citations (Scopus)

Mitochondrial complex III ROS regulate adipocyte differentiation

Tormos, K. V., Anso, E., Hamanaka, R. B., Eisenbart, J., Joseph, J., Kalyanaraman, B. & Chandel, N., Oct 5 2011, In : Cell Metabolism. 14, 4, p. 537-544 8 p.

Research output: Contribution to journalArticle

Electron Transport Complex III
Adipocytes
Reactive Oxygen Species
Organelle Biogenesis
Mesenchymal Stromal Cells
120 Citations (Scopus)

Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion

Loor, G., Kondapalli, J., Iwase, H., Chandel, N., Waypa, G. B., Guzy, R. D., Vanden Hoek, T. L. & Schumacker, P. T., Jul 1 2011, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1813, 7, p. 1382-1394 13 p.

Research output: Contribution to journalArticle

Oxidants
Reperfusion
Cell Death
Ischemia
phospholipid-hydroperoxide glutathione peroxidase
26 Citations (Scopus)

Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin

Mirkovic, I., Gault, W. J., Rahnama, M., Jenny, A., Gaengel, K., Bessette, D., Gottardi, C., Verheyen, E. M. & Mlodzik, M., Jun 1 2011, In : Nature Structural and Molecular Biology. 18, 6, p. 665-672 8 p.

Research output: Contribution to journalArticle

Catenins
Cell Polarity
Cadherins
Phosphotransferases
Cell Movement
164 Citations (Scopus)

NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. & Franzoso, G., Oct 1 2011, In : Nature Cell Biology. 13, 10, p. 1272-1279 8 p.

Research output: Contribution to journalArticle

Respiration
Homeostasis
Glycolysis
Energy Metabolism
Genetic Suppression
4 Citations (Scopus)

Nontuberculous mycobacterial hypersensitivity pneumonitis related to a home shower: Treatment and secondary prevention

Hankwitz, P. E., Cervia, J. S., Thomas, C. F., Fink, J. N., Marras, T. & Tomic, R., Jan 1 2011, In : BMJ Case Reports.

Research output: Contribution to journalArticle

Extrinsic Allergic Alveolitis
Secondary Prevention
Mycobacterium avium Complex
Nontuberculous Mycobacteria
Water
92 Citations (Scopus)

Nuclear β-catenin is increased in systemic sclerosis pulmonary fibrosis and promotes lung fibroblast migration and proliferation

Lam, A. P., Flozak, A. S., Russell, S. R., Wei, J., Jain, M., Mutlu, G. M., Budinger, GR. S., Feghali-Bostwick, C. A., Varga, J. & Gottardi, C., Nov 1 2011, In : American journal of respiratory cell and molecular biology. 45, 5, p. 915-922 8 p.

Research output: Contribution to journalArticle

Catenins
Pulmonary Fibrosis
Systemic Scleroderma
Fibroblasts
Lung
72 Citations (Scopus)

Obesity and primary graft dysfunction after lung transplantation: The lung transplant outcomes group obesity study

Lederer, D. J., Kawut, S. M., Wickersham, N., Winterbottom, C., Bhorade, S., Palmer, S. M., Lee, J., Diamond, J. M., Wille, K. M., Weinacker, A., Lama, V. N., Crespo, M., Orens, J. B., Sonett, J. R., Arcasoy, S. M., Ware, L. B. & Christie, J. D., Nov 1 2011, In : American journal of respiratory and critical care medicine. 184, 9, p. 1055-1061 7 p.

Research output: Contribution to journalArticle

Primary Graft Dysfunction
Lung Transplantation
Obesity
Transplants
Lung
41 Citations (Scopus)

P53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis

Dirisina, R., Katzman, R. B., Goretsky, T., Managlia, E., Mittal, N., Williams, D. B., Qiu, W., Yu, J., Chandel, N., Zhang, L. & Barrett, T. A., Jan 1 2011, In : Gastroenterology. 141, 3, p. 1036-1045 10 p.

Research output: Contribution to journalArticle

Colitis
Epithelial Cells
Apoptosis
Inflammation
Dextran Sulfate
46 Citations (Scopus)

Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice

Mutlu, E. A., Engen, P. A., Soberanes, S., Urich, D., Forsyth, C. B., Nigdelioglu, R., Chiarella, S. E., Radigan, K. A., Gonzalez, A., Jakate, S., Keshavarzian, A., Budinger, GR. S. & Mutlu, G. M., Jun 9 2011, In : Particle and Fibre Toxicology. 8, 19.

Research output: Contribution to journalArticle

Particulate Matter
Air Pollution
Air pollution
Oxidants
Permeability
62 Citations (Scopus)

Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms

Budinger, GR. S., McKell, J. L., Urich, D., Foiles, N., Weiss, I., Chiarella, S. E., Gonzalez, A., Soberanes, S., Ghio, A. J., Nigdelioglu, R., Mutlu, E. A., Radigan, K. A., Green, D., Kwaan, H. C. & Mutlu, G. M., Apr 20 2011, In : PloS one. 6, 4, e18525.

Research output: Contribution to journalArticle

Particulate Matter
Plasminogen Activator Inhibitor 1
Coagulation
coagulation
Pneumonia
21 Citations (Scopus)

Perivascular T-cell infiltration leads to sustained pulmonary artery remodeling after endothelial cell damage

Cuttica, M. J., Langenickel, T., Noguchi, A., Machado, R. F., Gladwin, M. T. & Boehm, M., Jul 1 2011, In : American journal of respiratory cell and molecular biology. 45, 1, p. 62-71 10 p.

Research output: Contribution to journalArticle

T-cells
Endothelial cells
Infiltration
Pulmonary Artery
Endothelial Cells
10 Citations (Scopus)

Pilot randomized study comparing two techniques of airway anaesthesia during curvilinear probe endobronchial ultrasound bronchoscopy (CP-EBUS)

Lee, H. J., Haas, A. R., Sterman, D. H., Solly, R., Vachani, A. & Gillespie, C. T., Jan 1 2011, In : Respirology. 16, 1, p. 102-106 5 p.

Research output: Contribution to journalArticle

Bronchoscopy
Lidocaine
Anesthesia
Catheters
Injections
4 Citations (Scopus)

Prolonged acute care in a 52-year-old man with respiratory failure: Lessons learned from 70-day intensive care unit hospitalization

Mishra, R. K., Alalawi, R., Raj, R. & Nugent, K. M., Jan 1 2011, In : Journal of Critical Care. 26, 5, p. 532.e9-532.e16

Research output: Contribution to journalArticle

Respiratory Insufficiency
Intensive Care Units
Hospitalization
Anxiety
Depression
114 Citations (Scopus)
Checklist
Physicians
Length of Stay
Critical Illness
Intensive Care Units

Pseudomonas aeruginosa Infection in Cystic Fibrosis: A Paradigm of Chronic Infection

Prickett, M. & Jain, M., Mar 1 2011, In : Clinical Pulmonary Medicine. 18, 2, p. 53-59 7 p.

Research output: Contribution to journalArticle

Pseudomonas Infections
Cystic Fibrosis
Pseudomonas aeruginosa
Infection
Virulence Factors
6 Citations (Scopus)

Pulmonary emboli detected by endobronchial ultrasound

Swartz, M. A. & Gillespie, C. T., Jun 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 11, 1 p.

Research output: Contribution to journalArticle

Doppler Duplex Ultrasonography
Doppler Ultrasonography
Bronchoscopy
Embolism
Pulmonary Embolism
71 Citations (Scopus)

Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: A randomized trial

Wunderink, R. G., Laterre, P. F., Francois, B., Perrotin, D., Artigas, A., Vidal, L. O., Lobo, S. M., San Juan, J., Hwang, S. C., Dugernier, T., LaRosa, S., Wittebole, X., Dhainaut, J. F., Doig, C., Mendelson, M. H., Zwingelstein, C., Su, G. & Opal, S., Jun 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 11, p. 1561-1568 8 p.

Research output: Contribution to journalArticle

Pneumonia
Placebos
Mortality
lipoprotein-associated coagulation inhibitor
Tifacogin
10 Citations (Scopus)

Reduced diffusion lung capacity in patients with type 2 diabetes mellitus predicts hospitalization for pneumonia

Klein, O. L., Smith, L. J., Tipping, M., Peng, J. & Williams, M. V., Apr 1 2011, In : Diabetes Research and Clinical Practice. 92, 1

Research output: Contribution to journalArticle

Lung Volume Measurements
Type 2 Diabetes Mellitus
Pneumonia
Diabetes Mellitus
Hospitalization
29 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
lung function
exercise
heart
Exercise
8 Citations (Scopus)

Risk factors for montelukast treatment failure in step-down therapy for controlled asthma

Drummond, M. B., Peters, S. P., Castro, M., Holbrook, J. T., Irvin, C. G., Smith, L. J., Wise, R. A. & Sugar, E. A., Dec 1 2011, In : Journal of Asthma. 48, 10, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

montelukast
Treatment Failure
Asthma
Adrenal Cortex Hormones
Therapeutics
17 Citations (Scopus)

Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis

Zhou, Q., Pardo, A., Königshoff, M., Eickelberg, O., Budinger, GR. S., Thavarajah, K., Gottardi, C., Jones, J., Varga, J., Selman, M., Sznajder, J. I., Raj, J. U. & Zhou, G., Sep 1 2011, In : FASEB Journal. 25, 9, p. 3032-3044 13 p.

Research output: Contribution to journalArticle

Fibroblasts
Fibrosis
Fibronectins
Integrins
Proteins

Salt-inducible kinase 1 is present in lung alveolar epithelial cells and regulates active sodium transport

Eneling, K., Chen, J., Welch, L. C., Takemori, H., Sznajder, J. I. & Bertorello, A. M., May 27 2011, In : Biochemical and Biophysical Research Communications. 409, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Active Biological Transport
Phosphotransferases
Salts
Sodium
21 Citations (Scopus)

Serum adiponectin is associated with adverse outcomes of asthma in men but not in women

Sood, A., Dominic, E., Qualls, C., Steffes, M. W., Thyagarajan, B., Smith, L. J., Lewis, C. E. & Jacobs, D. R., Dec 1 2011, In : Frontiers in Pharmacology. OCT, Article 55.

Research output: Contribution to journalArticle

Adiponectin
Asthma
Serum
Young Adult
Coronary Vessels
14 Citations (Scopus)

Serum carotenoid concentrations predict lung function evolution in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study

Thyagarajan, B., Meyer, K. A., Smith, L. J., Beckett, W. S., Williams, O. D., Gross, M. D. & Jacobs, D. R., Nov 1 2011, In : American Journal of Clinical Nutrition. 94, 5, p. 1211-1218 8 p.

Research output: Contribution to journalArticle

Carotenoids
Young Adult
Coronary Vessels
Lung
Serum
9 Citations (Scopus)

Socioeconomic Status is Positively Associated with Percent Emphysema on CT Scan. The MESA Lung Study

Lovasi, G. S., Diez Roux, A. V., Hoffman, E. A., Smith, L. J., Jiang, R., Carr, J. J. & Barr, R. G., Feb 1 2011, In : Academic Radiology. 18, 2, p. 199-204 6 p.

Research output: Contribution to journalArticle

Emphysema
Social Class
Atherosclerosis
Tomography
Lung

Substrate stiffness regulates extracellular matrix deposition by alveolar epithelial cells

Eisenberg, J. L., Safi, A., Wei, X., Espinosa, H. D., Budinger, G. R. S., Takawira, D., Hopkinson, S. B. & Jones, J. C. R., 2011, In : Research and Reports in Biology. 2011, p. 1-12

Research output: Contribution to journalArticle

36 Citations (Scopus)
Tocopherols
Inflammation
Bronchoalveolar Lavage Fluid
Pneumonia
Vitamin E

Teratoma of the ovary with sarcomatous transformation and pulmonary metastases

Go, L. H. T. & Corbridge, T. C., Mar 7 2011, In : TheScientificWorldJournal. 11, p. 584-586 3 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
207 Citations (Scopus)

The role of nuclear lamin B1 in cell proliferation and senescence

Shimi, T., Butin-Israeli, V., Adam, S. A., Hamanaka, R. B., Goldman, A. E., Lucas, C. A., Shumaker, D. K., Kosak, S. T., Chandel, N. S. & Goldman, R. D., Dec 15 2011, In : Genes and Development. 25, 24, p. 2579-2593 15 p.

Research output: Contribution to journalArticle

Cell Aging
Cell Proliferation
Reactive Oxygen Species
G1 Phase Cell Cycle Checkpoints
lamin B1
22 Citations (Scopus)

Time-resolved magnetic resonance angiography: Evaluation of intrapulmonary circulation parameters in pulmonary arterial hypertension

Jeong, H. J., Vakil, P., Sheehan, J. J., Shah, S. J., Cuttica, M. J., Carr, J., Carroll, T. J. & Davarpanah, A., Jan 1 2011, In : Journal of Magnetic Resonance Imaging. 33, 1, p. 225-231 7 p.

Research output: Contribution to journalArticle

Magnetic Resonance Angiography
Pulmonary Hypertension
Lung
Pulmonary Valve
Research Ethics Committees
8 Citations (Scopus)

Transcriptional activation of human GM3 synthase (hST3Gal V) gene by valproic acid in ARPE-19 human retinal pigment epithelial cells

Song, N., Kim, S. J., Kwon, H. Y., Son, S. W., Kim, K. S., Ahn, H. B. & Lee, Y. C., Jun 1 2011, In : BMB Reports. 44, 6, p. 405-409 5 p.

Research output: Contribution to journalArticle

Retinal Pigments
Valproic Acid
Transcriptional Activation
Genes
Epithelial Cells
62 Citations (Scopus)

Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells

Rogel, M. R., Soni, P. N., Troken, J. R., Sitikov, A., Trejo, H. E. & Ridge, K. M., Nov 1 2011, In : FASEB Journal. 25, 11, p. 3873-3883 11 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Vimentin
Repair
Wounds and Injuries
Cell Movement
123 Citations (Scopus)

Vimentin organization modulates the formation of lamellipodia

Helfand, B. T., Mendez, M. G., Murthy, S. N. P., Shumaker, D. K., Grin, B., Mahammad, S., Aebi, U., Wedig, T., Wu, Y. I., Hahn, K. M., Inagaki, M., Herrmann, H. & Goldman, R., Apr 15 2011, In : Molecular biology of the cell. 22, 8, p. 1274-1289 16 p.

Research output: Contribution to journalArticle

Pseudopodia
Vimentin
Intermediate Filaments
Fibroblasts
Phosphorylation
2010
7 Citations (Scopus)

A 71-year-old woman with myelofibrosis, hypoxemia, and pulmonary hypertension

Trow, T. K., Argento, A. C., Rubinowitz, A. N. & Decker, R., Dec 1 2010, In : Chest. 138, 6, p. 1506-1510 5 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Pulmonary Hypertension
Hypoxia
229 Citations (Scopus)

Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia

Reid, K. J., Baron, K. G., Lu, B., Naylor, E., Wolfe, L. & Zee, P. C., Oct 1 2010, In : Sleep Medicine. 11, 9, p. 934-940 7 p.

Research output: Contribution to journalArticle

Sleep Initiation and Maintenance Disorders
Sleep
Quality of Life
Exercise
Depression
9 Citations (Scopus)

Amiodarone-induced loculated pleural effusion: Case report and review of the literature

Uong, V., Nugent, K., Alalawi, R. & Raj, R., Feb 1 2010, In : Pharmacotherapy. 30, 2, 1 p.

Research output: Contribution to journalArticle

Amiodarone
Pleural Effusion
Chest Pain
Pulmonary Veins
Interstitial Lung Diseases
91 Citations (Scopus)

A phase i trial of repeated intrapleural adenoviral-mediated interferon-β gene transfer for mesothelioma and metastatic pleural effusions

Sterman, D. H., Recio, A., Haas, A. R., Vachani, A., Katz, S. I., Gillespie, C. T., Cheng, G., Sun, J., Moon, E., Pereira, L., Wang, X., Heitjan, D. F., Litzky, L., June, C. H., Vonderheide, R. H., Carroll, R. G. & Albelda, S. M., Apr 1 2010, In : Molecular Therapy. 18, 4, p. 852-860 9 p.

Research output: Contribution to journalArticle

Mesothelioma
Pleural Effusion
Interferons
Genes
Malignant Pleural Effusion
6 Citations (Scopus)

Asthma in adolescents and adults

Corbridge, S. & Corbridge, T. C., May 1 2010, In : American Journal of Nursing. 110, 5, p. 28-38 11 p.

Research output: Contribution to journalArticle

Asthma
Environmental Monitoring
Patient Education
Early Diagnosis
Chronic Disease
185 Citations (Scopus)

Beyond mortality: Future clinical research in acute lung injury

Spragg, R. G., Bernard, G. R., Checkley, W., Curtis, J. R., Gajic, O., Guyatt, G., Hall, J., Israel, E., Jain, M., Needham, D. M., Randolph, A. G., Rubenfeld, G. D., Schoenfeld, D., Thompson, B. T., Ware, L. B., Young, D. & Harabin, A. L., May 15 2010, In : American Journal of Respiratory and Critical Care Medicine. 181, 10, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Mortality
Research
National Heart, Lung, and Blood Institute (U.S.)
Clinical Trials
29 Citations (Scopus)

Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

Scatizzi, J. C., Hutcheson, J., Pope, R. M., Firestein, G. S., Koch, A. E., Mavers, M., Smason, A., Agrawal, H., Haines, G. K., Chandel, N., Hotchkiss, R. S. & Perlman, H. R., Feb 1 2010, In : Arthritis and rheumatism. 62, 2, p. 441-451 11 p.

Research output: Contribution to journalArticle

Myeloid Cells
Arthritis
Rheumatoid Arthritis
Apoptosis
Thioglycolates
147 Citations (Scopus)

Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity

Mutlu, G. M., Budinger, GR. S., Green, A. A., Urich, D., Soberanes, S., Chiarella, S. E., Alheid, G. F., McCrimmon, D. R., Szleifer, I. G. & Hersam, M., May 12 2010, In : Nano Letters. 10, 5, p. 1664-1670 7 p.

Research output: Contribution to journalArticle

Single-walled carbon nanotubes (SWCN)
toxicity
Toxicity
carbon nanotubes
mice
97 Citations (Scopus)

Categorization and impact of pulmonary hypertension in patients with advanced COPD

Cuttica, M. J., Kalhan, R., Shlobin, O. A., Ahmad, S., Gladwin, M., MacHado, R. F., Barnett, S. D. & Nathan, S. D., Dec 1 2010, In : Respiratory Medicine. 104, 12, p. 1877-1882 6 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Chronic Obstructive Pulmonary Disease
Hemodynamics
Cardiac Catheterization
Lung
27 Citations (Scopus)

Cellular inflammatory infiltrate in pneumonitis induced by a single moderate dose of thoracic X radiation in rats

Szabo, S., Ghosh, S. N., Fish, B. L., Bodiga, S., Tomic, R., Kumar, G., Morrow, N. V., Moulder, J. E., Jacobs, E. R. & Medhora, M., Apr 1 2010, In : Radiation Research. 173, 4, p. 545-556 12 p.

Research output: Contribution to journalArticle

Mast Cells
rats
Pneumonia
Thorax
X-Rays