Medicine, Pulmonary Division

Research Output 1949 2019

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Article
2011
6 Citations (Scopus)

Pulmonary emboli detected by endobronchial ultrasound

Swartz, M. A. & Gillespie, C. T., Jun 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 11, 1 p.

Research output: Contribution to journalArticle

Doppler Duplex Ultrasonography
Doppler Ultrasonography
Bronchoscopy
Embolism
Pulmonary Embolism
71 Citations (Scopus)

Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: A randomized trial

Wunderink, R. G., Laterre, P. F., Francois, B., Perrotin, D., Artigas, A., Vidal, L. O., Lobo, S. M., San Juan, J., Hwang, S. C., Dugernier, T., LaRosa, S., Wittebole, X., Dhainaut, J. F., Doig, C., Mendelson, M. H., Zwingelstein, C., Su, G. & Opal, S., Jun 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 11, p. 1561-1568 8 p.

Research output: Contribution to journalArticle

Pneumonia
Placebos
Mortality
lipoprotein-associated coagulation inhibitor
Tifacogin
10 Citations (Scopus)

Reduced diffusion lung capacity in patients with type 2 diabetes mellitus predicts hospitalization for pneumonia

Klein, O. L., Smith, L. J., Tipping, M., Peng, J. & Williams, M. V., Apr 1 2011, In : Diabetes Research and Clinical Practice. 92, 1

Research output: Contribution to journalArticle

Lung Volume Measurements
Type 2 Diabetes Mellitus
Pneumonia
Diabetes Mellitus
Hospitalization
29 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
lung function
exercise
heart
Exercise
8 Citations (Scopus)

Risk factors for montelukast treatment failure in step-down therapy for controlled asthma

Drummond, M. B., Peters, S. P., Castro, M., Holbrook, J. T., Irvin, C. G., Smith, L. J., Wise, R. A. & Sugar, E. A., Dec 1 2011, In : Journal of Asthma. 48, 10, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

montelukast
Treatment Failure
Asthma
Adrenal Cortex Hormones
Therapeutics
17 Citations (Scopus)

Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis

Zhou, Q., Pardo, A., Königshoff, M., Eickelberg, O., Budinger, GR. S., Thavarajah, K., Gottardi, C., Jones, J., Varga, J., Selman, M., Sznajder, J. I., Raj, J. U. & Zhou, G., Sep 1 2011, In : FASEB Journal. 25, 9, p. 3032-3044 13 p.

Research output: Contribution to journalArticle

Fibroblasts
Fibrosis
Fibronectins
Integrins
Proteins

Salt-inducible kinase 1 is present in lung alveolar epithelial cells and regulates active sodium transport

Eneling, K., Chen, J., Welch, L. C., Takemori, H., Sznajder, J. I. & Bertorello, A. M., May 27 2011, In : Biochemical and Biophysical Research Communications. 409, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Active Biological Transport
Phosphotransferases
Salts
Sodium
21 Citations (Scopus)

Serum adiponectin is associated with adverse outcomes of asthma in men but not in women

Sood, A., Dominic, E., Qualls, C., Steffes, M. W., Thyagarajan, B., Smith, L. J., Lewis, C. E. & Jacobs, D. R., Dec 1 2011, In : Frontiers in Pharmacology. OCT, Article 55.

Research output: Contribution to journalArticle

Adiponectin
Asthma
Serum
Young Adult
Coronary Vessels
15 Citations (Scopus)

Serum carotenoid concentrations predict lung function evolution in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study

Thyagarajan, B., Meyer, K. A., Smith, L. J., Beckett, W. S., Williams, O. D., Gross, M. D. & Jacobs, D. R., Nov 1 2011, In : American Journal of Clinical Nutrition. 94, 5, p. 1211-1218 8 p.

Research output: Contribution to journalArticle

Carotenoids
Young Adult
Coronary Vessels
Lung
Serum
21 Citations (Scopus)

Short women with severe sepsis-related acute lung injury receive lung protective ventilation less frequently: an observational cohort study.

Han, S., Martin, G. S., Maloney, J. P., Shanholtz, C., Barnes, K. C., Murray, S. & Sevransky, J. E., Dec 1 2011, In : Critical care (London, England). 15, 6

Research output: Contribution to journalArticle

Acute Lung Injury
Observational Studies
Ventilation
Sepsis
Cohort Studies
9 Citations (Scopus)

Socioeconomic Status is Positively Associated with Percent Emphysema on CT Scan. The MESA Lung Study

Lovasi, G. S., Diez Roux, A. V., Hoffman, E. A., Smith, L. J., Jiang, R., Carr, J. J. & Barr, R. G., Feb 1 2011, In : Academic Radiology. 18, 2, p. 199-204 6 p.

Research output: Contribution to journalArticle

Emphysema
Social Class
Atherosclerosis
Tomography
Lung

Substrate stiffness regulates extracellular matrix deposition by alveolar epithelial cells

Eisenberg, J. L., Safi, A., Wei, X., Espinosa, H. D., Budinger, G. R. S., Takawira, D., Hopkinson, S. B. & Jones, J. C. R., 2011, In : Research and Reports in Biology. 2011, p. 1-12

Research output: Contribution to journalArticle

37 Citations (Scopus)
Tocopherols
Inflammation
Bronchoalveolar Lavage Fluid
Pneumonia
Vitamin E

Teratoma of the ovary with sarcomatous transformation and pulmonary metastases

Go, L. H. T. & Corbridge, T. C., Mar 7 2011, In : TheScientificWorldJournal. 11, p. 584-586 3 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
Fatal Outcome
Germ Cell and Embryonal Neoplasms
Teratoma
Sarcoma
209 Citations (Scopus)

The role of nuclear lamin B1 in cell proliferation and senescence

Shimi, T., Butin-Israeli, V., Adam, S. A., Hamanaka, R. B., Goldman, A. E., Lucas, C. A., Shumaker, D. K., Kosak, S. T., Chandel, N. S. & Goldman, R. D., Dec 15 2011, In : Genes and Development. 25, 24, p. 2579-2593 15 p.

Research output: Contribution to journalArticle

Cell Aging
Cell Proliferation
Reactive Oxygen Species
G1 Phase Cell Cycle Checkpoints
lamin B1
23 Citations (Scopus)

Time-resolved magnetic resonance angiography: Evaluation of intrapulmonary circulation parameters in pulmonary arterial hypertension

Jeong, H. J., Vakil, P., Sheehan, J. J., Shah, S. J., Cuttica, M. J., Carr, J., Carroll, T. J. & Davarpanah, A., Jan 1 2011, In : Journal of Magnetic Resonance Imaging. 33, 1, p. 225-231 7 p.

Research output: Contribution to journalArticle

Magnetic Resonance Angiography
Pulmonary Hypertension
Lung
Pulmonary Valve
Research Ethics Committees
8 Citations (Scopus)

Transcriptional activation of human GM3 synthase (hST3Gal V) gene by valproic acid in ARPE-19 human retinal pigment epithelial cells

Song, N., Kim, S. J., Kwon, H. Y., Son, S. W., Kim, K. S., Ahn, H. B. & Lee, Y. C., Jun 1 2011, In : BMB Reports. 44, 6, p. 405-409 5 p.

Research output: Contribution to journalArticle

Retinal Pigments
Valproic Acid
Transcriptional Activation
Genes
Epithelial Cells
62 Citations (Scopus)

Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells

Rogel, M. R., Soni, P. N., Troken, J. R., Sitikov, A., Trejo, H. E. & Ridge, K. M., Nov 1 2011, In : FASEB Journal. 25, 11, p. 3873-3883 11 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Vimentin
Repair
Wounds and Injuries
Cell Movement
127 Citations (Scopus)

Vimentin organization modulates the formation of lamellipodia

Helfand, B. T., Mendez, M. G., Murthy, S. N. P., Shumaker, D. K., Grin, B., Mahammad, S., Aebi, U., Wedig, T., Wu, Y. I., Hahn, K. M., Inagaki, M., Herrmann, H. & Goldman, R. D., Apr 15 2011, In : Molecular biology of the cell. 22, 8, p. 1274-1289 16 p.

Research output: Contribution to journalArticle

Pseudopodia
Vimentin
Intermediate Filaments
Fibroblasts
Phosphorylation
2010
7 Citations (Scopus)

A 71-year-old woman with myelofibrosis, hypoxemia, and pulmonary hypertension

Trow, T. K., Argento, A. C., Rubinowitz, A. N. & Decker, R., Dec 1 2010, In : Chest. 138, 6, p. 1506-1510 5 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Pulmonary Hypertension
Hypoxia
239 Citations (Scopus)

Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia

Reid, K. J., Baron, K. G., Lu, B., Naylor, E., Wolfe, L. & Zee, P. C., Oct 1 2010, In : Sleep Medicine. 11, 9, p. 934-940 7 p.

Research output: Contribution to journalArticle

Sleep Initiation and Maintenance Disorders
Sleep
Quality of Life
Exercise
Depression
9 Citations (Scopus)

Amiodarone-induced loculated pleural effusion: Case report and review of the literature

Uong, V., Nugent, K., Alalawi, R. & Raj, R., Feb 1 2010, In : Pharmacotherapy. 30, 2, 1 p.

Research output: Contribution to journalArticle

Amiodarone
Pleural Effusion
Chest Pain
Pulmonary Veins
Interstitial Lung Diseases
92 Citations (Scopus)

A phase i trial of repeated intrapleural adenoviral-mediated interferon-β gene transfer for mesothelioma and metastatic pleural effusions

Sterman, D. H., Recio, A., Haas, A. R., Vachani, A., Katz, S. I., Gillespie, C. T., Cheng, G., Sun, J., Moon, E., Pereira, L., Wang, X., Heitjan, D. F., Litzky, L., June, C. H., Vonderheide, R. H., Carroll, R. G. & Albelda, S. M., Apr 1 2010, In : Molecular Therapy. 18, 4, p. 852-860 9 p.

Research output: Contribution to journalArticle

Mesothelioma
Pleural Effusion
Interferons
Genes
Malignant Pleural Effusion
6 Citations (Scopus)

Asthma in adolescents and adults

Corbridge, S. & Corbridge, T. C., May 1 2010, In : American Journal of Nursing. 110, 5, p. 28-38 11 p.

Research output: Contribution to journalArticle

Asthma
Environmental Monitoring
Patient Education
Early Diagnosis
Chronic Disease
187 Citations (Scopus)

Beyond mortality: Future clinical research in acute lung injury

Spragg, R. G., Bernard, G. R., Checkley, W., Curtis, J. R., Gajic, O., Guyatt, G., Hall, J., Israel, E., Jain, M., Needham, D. M., Randolph, A. G., Rubenfeld, G. D., Schoenfeld, D., Thompson, B. T., Ware, L. B., Young, D. & Harabin, A. L., May 15 2010, In : American Journal of Respiratory and Critical Care Medicine. 181, 10, p. 1121-1127 7 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Mortality
Research
National Heart, Lung, and Blood Institute (U.S.)
Clinical Trials
29 Citations (Scopus)

Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

Scatizzi, J. C., Hutcheson, J., Pope, R. M., Firestein, G. S., Koch, A. E., Mavers, M., Smason, A., Agrawal, H., Haines, G. K., Chandel, N. S., Hotchkiss, R. S. & Perlman, H., Feb 1 2010, In : Arthritis and rheumatism. 62, 2, p. 441-451 11 p.

Research output: Contribution to journalArticle

Myeloid Cells
Arthritis
Rheumatoid Arthritis
Apoptosis
Thioglycolates
148 Citations (Scopus)

Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity

Mutlu, G. M., Budinger, GR. S., Green, A. A., Urich, D., Soberanes, S., Chiarella, S. E., Alheid, G. F., McCrimmon, D. R., Szleifer, I. G. & Hersam, M., May 12 2010, In : Nano Letters. 10, 5, p. 1664-1670 7 p.

Research output: Contribution to journalArticle

Single-walled carbon nanotubes (SWCN)
toxicity
Toxicity
carbon nanotubes
mice
98 Citations (Scopus)

Categorization and impact of pulmonary hypertension in patients with advanced COPD

Cuttica, M. J., Kalhan, R., Shlobin, O. A., Ahmad, S., Gladwin, M., MacHado, R. F., Barnett, S. D. & Nathan, S. D., Dec 1 2010, In : Respiratory Medicine. 104, 12, p. 1877-1882 6 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Chronic Obstructive Pulmonary Disease
Hemodynamics
Cardiac Catheterization
Lung
29 Citations (Scopus)

Cellular inflammatory infiltrate in pneumonitis induced by a single moderate dose of thoracic X radiation in rats

Szabo, S., Ghosh, S. N., Fish, B. L., Bodiga, S., Tomic, R., Kumar, G., Morrow, N. V., Moulder, J. E., Jacobs, E. R. & Medhora, M., Apr 1 2010, In : Radiation Research. 173, 4, p. 545-556 12 p.

Research output: Contribution to journalArticle

Mast Cells
rats
Pneumonia
Thorax
X-Rays
19 Citations (Scopus)
Lipopolysaccharides
Blood Cells
Gene Expression
In Vitro Techniques
Cell Separation
57 Citations (Scopus)

Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome

Bhorade, S. M., Chen, H., Molinero, L., Liao, C., Garrity, E. R., Vigneswaran, W. T., Shilling, R., Sperling, A., Chong, A. & Alegre, M. L., Sep 15 2010, In : Transplantation. 90, 5, p. 540-546 7 p.

Research output: Contribution to journalArticle

Bronchiolitis Obliterans
Bronchoalveolar Lavage
Lung
Chemokine CCL22
Transplantation Tolerance
16 Citations (Scopus)

Donor transmission of malignant melanoma in a lung transplant recipient 32 years after curative resection

Bajaj, N. S., Watt, C., Hadjiliadis, D., Gillespie, C., Haas, A. R., Pochettino, A., Mendez, J., Sterman, D. H., Schuchter, L. M., Christie, J. D., Lee, J. C. & Ahya, V. N., Jul 1 2010, In : Transplant International. 23, 7

Research output: Contribution to journalArticle

Melanoma
Tissue Donors
Lung
Transplantation
Transplants
28 Citations (Scopus)

E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFα-induced JNK activation

Yang, Y., Do, H. C., Tian, X., Zhang, C., Liu, X., Dada, L., Sznajder, J. I. & Liu, J., Jul 27 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 30, p. 13444-13449 6 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Equidae
Zinc Fingers
Cell Death
TNF Receptor-Associated Factor 2
65 Citations (Scopus)
Hypercapnia
Macrophages
Phagocytosis
Interleukin-6
Tumor Necrosis Factor-alpha
52 Citations (Scopus)

Expanded clinical presentation of community-acquired methicillin-resistant Staphylococcus aureus pneumonia

Lobo, L. J., Reed, K. D. & Wunderink, R. G., Jul 1 2010, In : Chest. 138, 1, p. 130-136 7 p.

Research output: Contribution to journalArticle

Staphylococcal Pneumonia
Methicillin-Resistant Staphylococcus aureus
Exotoxins
Pneumonia
Linezolid
23 Citations (Scopus)

Extracellular signal-regulated kinase (ERK) participates in the hypercapnia-induced Na,K-ATPase downregulation

Welch, L. C., Lecuona, E., Briva, A., Trejo, H. E., Dada, L. & Sznajder, J. I., Sep 1 2010, In : FEBS Letters. 584, 18, p. 3985-3989 5 p.

Research output: Contribution to journalArticle

Hypercapnia
Extracellular Signal-Regulated MAP Kinases
Adenosine Triphosphatases
Down-Regulation
Endocytosis
22 Citations (Scopus)

FLIP: A novel regulator of macrophage differentiation and granulocyte homeostasis

Huang, Q-Q., Perlman, H. R., Huang, Z., Birkett, R., Kan, L., Agrawal, H., Misharin, A., Gurbuxani, S., Crispino, J. D. & Pope, R. M., Dec 2 2010, In : Blood. 116, 23, p. 4968-4977 10 p.

Research output: Contribution to journalArticle

Macrophages
Granulocytes
Homeostasis
Bone
Extramedullary Hematopoiesis
136 Citations (Scopus)

Genetic ancestry in lung-function predictions

Kumar, R., Seibold, M. A., Aldrich, M. C., Williams, L. K., Reiner, A. P., Colangelo, L., Galanter, J., Gignoux, C., Hu, D., Sen, S., Choudhry, S., Peterson, E. L., Rodriguez-Santana, J., Rodriguez-Cintron, W., Nalls, M. A., Leak, T. S., O'Meara, E., Meibohm, B., Kritchevsky, S. B., Li, R. & 8 others, Harris, T. B., Nickerson, D. A., Fornage, M., Enright, P., Ziv, E., Smith, L. J., Liu, K. & Burchard, E. G., Jul 22 2010, In : New England Journal of Medicine. 363, 4, p. 321-330 10 p.

Research output: Contribution to journalArticle

Lung
African Americans
Health
Forced Expiratory Volume
Body Composition
9 Citations (Scopus)

Genetic variation in MYLK and lung injury in children and adults with community-acquired pneumonia

Russell, R., Quasney, M. W., Halligan, N., Li, S. H., Simpson, P., Waterer, G., Wunderink, R. G. & Dahmer, M. K., Jan 1 2010, In : Pediatric Critical Care Medicine. 11, 6, p. 731-736 6 p.

Research output: Contribution to journalArticle

Lung Injury
Myosin-Light-Chain Kinase
Single Nucleotide Polymorphism
Pneumonia
Genes
6 Citations (Scopus)

Hyul-Tong-Ryung suppresses PMA-induced MMP-9 expression by inhibiting AP-1-mediated gene expression via ERK1/2 signaling pathway in MCF-7 human breast cancer cells

Kim, K. S., Yao, L., Lee, Y. C., Chung, E., Kim, K. M., Kwak, Y. J., Kim, S. J., Cui, Z. & Lee, J. H., Dec 1 2010, In : Immunopharmacology and Immunotoxicology. 32, 4, p. 600-606 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Transcription Factor AP-1
Gene expression
Acetates
Cells
24 Citations (Scopus)

Insulin regulates alveolar epithelial function by inducing Na +/K+-ATPase translocation to the plasma membrane in a process mediated by the action of Akt

Comellas, A. P., Kelly, A. M., Trejo, H. E., Briva, A., Lee, J., Sznajder, J. I. & Dada, L. A., Apr 15 2010, In : Journal of cell science. 123, 8, p. 1343-1351 9 p.

Research output: Contribution to journalArticle

Cell Membrane
Insulin
rab GTP-Binding Proteins
Alveolar Epithelial Cells
GTPase-Activating Proteins
45 Citations (Scopus)

Inter-connection between mitochondria and HIFs

Tormos, K. V. & Chandel, N., Apr 1 2010, In : Journal of Cellular and Molecular Medicine. 14, 4, p. 795-804 10 p.

Research output: Contribution to journalArticle

Mitochondria
Respiration
Oxidative Stress
Hypoxia-Inducible Factor 1
Glycolysis
19 Citations (Scopus)

Joubert syndrome associated with severe central sleep apnea

Wolfe, L., Lakadamyali, H. & Mutlu, G. M., Aug 15 2010, In : Journal of Clinical Sleep Medicine. 6, 4, p. 384-388 5 p.

Research output: Contribution to journalArticle

Central Sleep Apnea
Wakefulness
Tooth
Respiration
Oxygen
13 Citations (Scopus)

Lenalidomide-induced interstitial lung disease

Chen, Y., Kiatsimkul, P., Nugent, K. & Raj, R., Mar 1 2010, In : Pharmacotherapy. 30, 3

Research output: Contribution to journalArticle

Interstitial Lung Diseases
Lung
Drug-Related Side Effects and Adverse Reactions
Multiple Myeloma
Dinoprostone

Lenalidomide-induced interstitial lung disease.

Chen, Y., Kiatsimkul, P., Nugent, K. & Raj, R., Mar 1 2010, In : Pharmacotherapy. 30, 3, 1 p.

Research output: Contribution to journalArticle

Interstitial Lung Diseases
Lung
Drug-Related Side Effects and Adverse Reactions
Prostaglandins E
Multiple Myeloma
6 Citations (Scopus)

Levels of transferrin in bronchoalveolar lavage fluid in sarcoidosis

Shigemura, M., Nasuhara, Y., Konno, S., Hattori, T., Shimizu, C., Matsuno, K. & Nishimura, M., Apr 1 2010, In : Lung. 188, 2, p. 151-157 7 p.

Research output: Contribution to journalArticle

Bronchoalveolar Lavage Fluid
Transferrin
Sarcoidosis
Serum
Interleukin-2 Receptors
29 Citations (Scopus)

Lung Function in Young Adults Predicts Airflow Obstruction 20 Years Later

Kalhan, R., Arynchyn, A., Colangelo, L. A., Dransfield, M. T., Gerald, L. B. & Smith, L. J., May 1 2010, In : American Journal of Medicine. 123, 5

Research output: Contribution to journalArticle

Forced Expiratory Volume
Young Adult
Vital Capacity
Lung
Smoking
107 Citations (Scopus)

Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis

Loor, G., Kondapalli, J., Schriewer, J. M., Chandel, N., Vanden Hoek, T. L. & Schumacker, P. T., Dec 15 2010, In : Free Radical Biology and Medicine. 49, 12, p. 1925-1936 12 p.

Research output: Contribution to journalArticle

Vitamin K 3
Cell death
Reactive Oxygen Species
Cell Death
Chemical activation
782 Citations (Scopus)

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Weinberg, F., Hamanaka, R., Wheaton, W. W., Weinberg, S., Joseph, J., Lopez, M., Kalyanaraman, B., Mutlu, G. M., Budinger, GR. S. & Chandel, N., May 11 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 19, p. 8788-8793 6 p.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Growth
Oxidative Phosphorylation
Carcinogenesis
Adenosine Triphosphate
21 Citations (Scopus)

Mitochondrial reactive oxygen species are required for hypoxia-induced degradation of keratin intermediate filaments

Na, N., Chandel, N. S., Litvan, J. & Ridge, K. M., Mar 1 2010, In : FASEB Journal. 24, 3, p. 799-809 11 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Keratins
Alveolar Epithelial Cells
Reactive Oxygen Species
Degradation