Medicine, Pulmonary Division

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2008

A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation

Lin, X., David, C. A., Donnelly, J. B., Michaelides, M., Chandel, N. S., Huang, X., Warrior, U., Weinberg, F., Tormos, K. V., Fesik, S. W. & Shen, Y., Jan 8 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 1, p. 174-179 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome

Morris, P. E., Papadakos, P., Russell, J. A., Wunderink, R., Schuster, D. P., Truwit, J. D., Vincent, J. L. & Bernard, G. R., Mar 2008, In : Critical care medicine. 36, 3, p. 782-788 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung

Taranova, A. G., Maldonado, D., Vachon, C. M., Jacobsen, E. A., Abdala-Valencia, H., McGarry, M. P., Ochkur, S. I., Protheroe, C. A., Doyle, A., Grant, C. S., Cook-Mills, J., Birnbaumer, L., Lee, N. A. & Lee, J. J., Oct 15 2008, In : Cancer Research. 68, 20, p. 8582-8589 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

A mechanism of benefit of soy genistein in asthma: Inhibition of eosinophil p38-dependent leukotriene synthesis

Kalhan, R., Smith, L. J., Nlend, M. C., Nair, A., Hixon, J. L. & Sporn, P. H. S., Jan 2008, In : Clinical and Experimental Allergy. 38, 1, p. 103-112 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

Vadász, I., Dada, L. A., Briva, A., Trejo, H. E., Welch, L. C., Chen, J., Tóth, P. T., Lecuona, E., Witters, L. A., Schumacker, P. T., Chandel, N. S., Seeger, W. & Sznajder, J. I., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 752-762 11 p.

Research output: Contribution to journalArticle

115 Scopus citations

Association between asthma and serum adiponectin concentration in women

Sood, A., Cui, X., Quails, C., Beckett, W. S., Gross, M. D., Steffes, M. W., Smith, L. J. & Jacobs, D. R., Oct 2008, In : Thorax. 63, 10, p. 877-882 6 p.

Research output: Contribution to journalArticle

97 Scopus citations

Carbonic anhydrase II and alveolar fluid reabsorption during hypercapnia

Chen, J., Lecuona, E., Briva, A., Welch, L. C. & Sznajder, J. I., Jan 2008, In : American journal of respiratory cell and molecular biology. 38, 1, p. 32-37 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells

Lam, A. P. & Dean, D. A., Jun 2008, In : Journal of Gene Medicine. 10, 6, p. 668-678 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Cylex ImmuKnow Assay Levels Are Lower in Lung Transplant Recipients With Infection

Bhorade, S. M., Janata, K., Vigneswaran, W. T., Alex, C. G. & Garrity, E. R., Sep 1 2008, In : Journal of Heart and Lung Transplantation. 27, 9, p. 990-994 5 p.

Research output: Contribution to journalArticle

76 Scopus citations

Derivation of a triage algorithm for chest radiography of community-acquired pneumonia patients in the emergency department

Kyriacou, D. N., Yarnold, P. R., Soltysik, R. C., Self, W. H., Wunderink, R. G., Schmitt, B. P., Parada, J. P. & Adams, J. G., Jan 2008, In : Academic Emergency Medicine. 15, 1, p. 40-44 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Early microbiological response to linezolid vs vancomycin in ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus

Wunderink, R. G., Mendelson, M. H., Somero, M. S., Fabian, T. C., May, A. K., Bhattacharyya, H., Leeper, K. V. & Solomkin, J. S., Jan 1 2008, In : Chest. 134, 6, p. 1200-1207 8 p.

Research output: Contribution to journalArticle

87 Scopus citations

Effect of an inhaled glucocorticoid on endothelial function in healthy smokers

Mendes, E. S., Horvath, G., Rebolledo, P., Monzon, M. E., Casalino-Matsuda, S. M. & Wanner, A., Jul 1 2008, In : Journal of applied physiology. 105, 1, p. 54-57 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: A multicenter, randomized study

Chastre, J., Wunderink, R., Prokocimer, P., Lee, M., Kaniga, K. & Friedland, I., Apr 2008, In : Critical care medicine. 36, 4, p. 1089-1096 8 p.

Research output: Contribution to journalArticle

212 Scopus citations

Evolution of Pseudomonas aeruginosa type III secretion in cystic fibrosis: a paradigm of chronic infection

Jain, M., Bar-Meir, M., McColley, S. A., Cullina, J., Potter, E., Powers, C., Prickett, M., Seshadri, R., Jovanovic, B., Petrocheilou, A., King, J. D. & Hauser, A. R., Jan 1 2008, In : Translational Research. 152, 6, p. 257-264 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Health care-associated infection (HAI): A critical appraisal of the emerging threat - Proceedings of the HAI Summit

Kollef, M. H., Napolitano, L. M., Solomkin, J. S., Wunderink, R. G., Bae, I. G., Fowler, V. G., Balk, R. A., Stevens, D. L., Rahal, J. J., Shorr, A. F., Linden, P. K. & Micek, S. T., Oct 1 2008, In : Clinical Infectious Diseases. 47, SUPPL.2, p. S55-S99

Research output: Contribution to journalArticle

57 Scopus citations

Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells

Monzón, M. E., Manzanares, D., Schmid, N., Casalino-Matsuda, S. M. & Forteza, R. M., Sep 1 2008, In : American journal of respiratory cell and molecular biology. 39, 3, p. 289-295 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein

Zhou, G., Dada, L. A., Chandel, N. S., Iwai, K., Lecuona, E., Ciechanover, A. & Sznajder, J. I., May 2008, In : FASEB Journal. 22, 5, p. 1335-1342 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Longitudinal association of body mass index with lung function: The CARDIA Study

Thyagarajan, B., Jacobs, D. R., Apostol, G. G., Smith, L. J., Jensen, R. L., Crapo, R. O., Barr, R. G., Lewis, C. E. & Williams, O. D., Apr 4 2008, In : Respiratory Research. 9, 31.

Research output: Contribution to journalArticle

84 Scopus citations
269 Scopus citations

Lung transplantation: The new lung-allocation system

Stern, E. & Bhorade, S. M., Aug 1 2008, In : Expert Review of Respiratory Medicine. 2, 4, p. 473-478 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Micromechanical properties of keratin intermediate filament networks

Sivaramakrishnan, S., DeGiulio, J. V., Lorand, L., Goldman, R. D. & Ridge, K. M., Jan 22 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 3, p. 889-894 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Novel steroid receptor phyto-modulator compound a inhibits growth and survival of prostate cancer cells

Yemelyanov, A., Czwornog, J., Gera, L., Joshi, S., Chatterton Jr, R. T. & Budunova, I., Jun 15 2008, In : Cancer Research. 68, 12, p. 4763-4773 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Overexpression of the Na-K-ATPase α2-subunit improves lung liquid clearance during ventilation-induced lung injury

Adir, Y., Welch, L. C., Dumasius, V., Factor, P., Sznajder, J. I. & Ridge, K. M., Jun 2008, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 294, 6, p. L1233-L1237

Research output: Contribution to journalArticle

16 Scopus citations

Plasma carboxy-terminal peptide of procollagen type I is an independent predictor of diastolic function in patients with advanced systolic heart failure

Roongsritong, C., Sadhu, A., Pierce, M., Raj, R. & Simoni, J., Nov 1 2008, In : Congestive Heart Failure. 14, 6, p. 302-306 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling

Lal, M., Song, X., Pluznick, J. L., Di Giovanni, V., Merrick, D. M., Rosenblum, N. D., Chauvet, V., Gottardi, C. J., Pei, Y. & Caplan, M. J., 2008, In : Human molecular genetics. 17, 20, p. 3105-3117 13 p.

Research output: Contribution to journalArticle

121 Scopus citations

PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a)

Emerling, B. M., Weinberg, F., Liu, J. L., Mak, T. W. & Chandel, N. S., Feb 19 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 7, p. 2622-2627 6 p.

Research output: Contribution to journalArticle

138 Scopus citations

Regulation of alveolar epithelial function by hypoxia

Zhou, G., Dada, L. A. & Sznajder, J. I., May 2008, In : European Respiratory Journal. 31, 5, p. 1107-1113 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Role of the transgenic human thyrotropin receptor A-subunit in thyroiditis induced by A-subunit immunization and regulatory T cell depletion

Mizutori, Y., Nagayama, Y., Flower, D., Misharin, A., Aliesky, H. A., Rapoport, B. & McLachlan, S. M., Dec 2008, In : Clinical and Experimental Immunology. 154, 3, p. 305-315 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Stretch-induced activation of AMP kinase in the lung requires dystroglycan

Budinger, G. R. S., Urich, D., DeBiase, P. J., Chiarella, S. E., Burgess, Z. O., Baker, C. M., Soberanes, S., Mutlu, G. M. & Jones, J. C. R., Dec 1 2008, In : American journal of respiratory cell and molecular biology. 39, 6, p. 666-672 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

The A- and B-type nuclear lamin networks: Microdomains involved in chromatin organization and transcription

Shimi, T., Pfleghaar, K., Kojima, S. I., Pack, C. G., Solovei, I., Goldman, A. E., Adam, S. A., Shumaker, D. K., Kinjo, M., Cremer, T. & Goldman, R. D., Dec 15 2008, In : Genes and Development. 22, 24, p. 3409-3421 13 p.

Research output: Contribution to journalArticle

290 Scopus citations

The AP-2α transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene

Choi, H. J., Chung, T. W., Kim, S. J., Cho, S. Y., Lee, Y. S., Lee, Y. C., Ko, J. H. & Kim, C. H., May 1 2008, In : Glycobiology. 18, 5, p. 395-407 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

The highly conserved nuclear lamin Ig-fold binds to PCNA: Its role in DNA replication

Shumaker, D. K., Solimando, L., Sengupta, K., Shimi, T., Adam, S. A., Grunwald, A., Strelkov, S. V., Aebi, U., Cardoso, M. C. & Goldman, R. D., Apr 21 2008, In : Journal of Cell Biology. 181, 2, p. 269-280 12 p.

Research output: Contribution to journalArticle

74 Scopus citations

TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells

Miyajima, N., Maruyama, S., Bohgaki, M., Kano, S., Shigemura, M., Shinohara, N., Nonomura, K. & Hatakeyama, S., May 1 2008, In : Cancer Research. 68, 9, p. 3486-3494 9 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Ubiquitin-proteasome-mediated degradation of keratin intermediate filaments in mechanically stimulated A549 cells

Jaitovich, A., Mehta, S., Na, N., Ciechanover, A., Goldman, R. D. & Ridge, K. M., Sep 12 2008, In : Journal of Biological Chemistry. 283, 37, p. 25348-25355 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Ubiquitylation of ε-COP by PIRH2 and regulation of the secretion of PSA

Maruyama, S., Miyajima, N., Bohgaki, M., Tsukiyama, T., Shigemura, M., Nonomura, K. & Hatakeyama, S., Jan 2008, In : Molecular and Cellular Biochemistry. 307, 1-2, p. 73-82 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Using simulation to enhance knowledge and confidence

Corbridge, S. J., McLaughlin, R., Tiffen, J., Wade, L., Templin, R. & Corbridge, T. C., Jun 2008, In : Nurse Practitioner. 33, 6, p. 12-13 2 p.

Research output: Contribution to journalArticle

17 Scopus citations

VE-cadherin and β-catenin binding dynamics during histamine-induced endothelial hyperpermeability

Guo, M., Breslin, J. W., Wu, M. H., Gottardi, C. J. & Yuan, S. Y., Apr 2008, In : American Journal of Physiology - Cell Physiology. 294, 4, p. C977-C984

Research output: Contribution to journalArticle

47 Scopus citations
2009

A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia

Laterre, P. F., Opal, S. M., Abraham, E., LaRosa, S. P., Creasey, A. A., Xie, F., Poole, L. & Wunderink, R. G., Mar 15 2009, In : Critical Care. 13, 2, R36.

Research output: Contribution to journalArticle

36 Scopus citations

Activity of the β-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion

Maher, M. T., Flozak, A. S., Stocker, A. M., Chenn, A. & Gottardi, C. J., Jul 27 2009, In : Journal of Cell Biology. 186, 2, p. 219-228 10 p.

Research output: Contribution to journalArticle

95 Scopus citations

Advanced locally invasive squamous cell carcinoma

Pankratz, M. M., Chandler, R., Otahbachi, M., Nugent, K. & Raj, R., Jan 1 2009, In : American Journal of the Medical Sciences. 338, 1, 1 p.

Research output: Contribution to journalArticle

Association of circulating adhesion molecules with lung function: The CARDIA study

Thyagarajan, B., Smith, L. J., Barr, R. G., Gross, M. D., Sood, A., Kalhan, R. & Jacobs, D. R., Jun 1 2009, In : Chest. 135, 6, p. 1481-1487 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Attenuation of induced hyperthyroidism in mice by pretreatment with thyrotropin receptor protein: Deviation of thyroid-stimulating to nonfunctional antibodies

Misharin, A. V., Nagayama, Y., Aliesky, H. A., Mizutori, Y., Rapoport, B. & McLachlan, S. M., Aug 2009, In : Endocrinology. 150, 8, p. 3944-3952 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK

Shroff, E. H., Snyder, C. M., Budinger, G. R. S., Jain, M., Chew, T. L., Khuon, S., Perlman, H. & Chandel, N. S., May 21 2009, In : PloS one. 4, 5, e5646.

Research output: Contribution to journalArticle

21 Scopus citations

Cananea copper mine: An international effort to improve hazardous working conditions in Mexico

Zubieta, I. X., Brown, G., Cohen, R. & Medina, E., Jan 1 2009, In : International Journal of Occupational and Environmental Health. 15, 1, p. 14-20 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Central Airways Obstruction Due to Aspergillus fumigatus After Lung Transplantation

Cerceo, E., Kotloff, R. M., Hadjiliadis, D., Ahya, V. N., Pochettino, A., Gillespie, C. & Christie, J. D., May 2009, In : Journal of Heart and Lung Transplantation. 28, 5, p. 515-519 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Critical role of serum response factor in pulmonary myofibroblast differentiation induced by TGF-β

Sandbo, N., Kregel, S., Taurin, S., Bhorade, S. & Dulin, N. O., Sep 1 2009, In : American journal of respiratory cell and molecular biology. 41, 3, p. 332-338 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

Elevated CO2 levels affect development, motility, and fertility and extend life span in Caenorhabditis elegans

Sharabi, K., Hurwitz, A., Simon, A. J., Beitel, G. J., Morimoto, R. I., Rechavi, G., Sznajder, J. I. & Gruenbaum, Y., Mar 10 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 10, p. 4024-4029 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection

Helenius, I. T., Krupinski, T., Turnbull, D. W., Gruenbaum, Y., Silverman, N., Johnson, E. A., Sporn, P. H. S., Sznajder, J. I. & Beitel, G. J., Nov 3 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 44, p. 18710-18715 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Endothelin-1 impairs alveolar epithelial function via endothelial ET B receptor

Comellas, A. P., Briva, A., Dada, L. A., Butti, M. L., Trejo, H. E., Yshii, C., Azzam, Z. S., Litvan, J., Chen, J., Lecuona, E., Pesce, L. M., Yanagisawa, M. & Sznajder, J. I., Jan 15 2009, In : American journal of respiratory and critical care medicine. 179, 2, p. 113-122 10 p.

Research output: Contribution to journalArticle

24 Scopus citations