Medicine, Pulmonary Division

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2009

Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS

Klimova, T. A., Bell, E. L., Shroff, E. H., Weinberg, F. D., Snyder, C. M., Dimri, G. P., Schumacker, P. T., Scott Budinger, G. R. & Chandel, N. S., Mar 2009, In : FASEB Journal. 23, 3, p. 783-794 12 p.

Research output: Contribution to journalArticle

44 Scopus citations
152 Scopus citations

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

Emerling, B. M., Weinberg, F., Snyder, C., Burgess, Z., Mutlu, G. M., Viollet, B., Budinger, G. R. S. & Chandel, N. S., May 15 2009, In : Free Radical Biology and Medicine. 46, 10, p. 1386-1391 6 p.

Research output: Contribution to journalArticle

203 Scopus citations

Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia

Restrepo, M. I., Mortensen, E. M., Waterer, G. W., Wunderink, R. G., Coalson, J. J. & Anzueto, A., Jan 1 2009, In : European Respiratory Journal. 33, 1, p. 153-159 7 p.

Research output: Contribution to journalArticle

140 Scopus citations

Introduction

Schatz, M., Kazzi, A. A. N., Brenner, B., Camargo, C. A., Corbridge, T., Krishnan, J. A., Nowak, R. & Rachelefsky, G., Aug 1 2009, In : Journal of Emergency Medicine. 37, 2 SUPPL., p. S1-S5

Research output: Contribution to journalArticle

4 Scopus citations

Introduction

Schatz, M., Kazzi, A. A. N., Brenner, B., Camargo, C. A., Corbridge, T. C., Krishnan, J. A., Nowak, R. & Rachelefsky, G., Aug 1 2009, In : Journal of Allergy and Clinical Immunology. 124, 2 SUPPL.

Research output: Contribution to journalArticle

8 Scopus citations

Intubation and mechanical ventilation of the asthmatic patient in respiratory failure

Brenner, B., Corbridge, T. & Kazzi, A., Aug 1 2009, In : Journal of Allergy and Clinical Immunology. 124, 2 SUPPL., p. S19-S28

Research output: Contribution to journalArticle

22 Scopus citations

Intubation and mechanical ventilation of the asthmatic patient in respiratory failure

Brenner, B., Corbridge, T. & Kazzi, A., Aug 1 2009, In : Proceedings of the American Thoracic Society. 6, 4, p. 371-379 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Intubation and Mechanical Ventilation of the Asthmatic Patient in Respiratory Failure

Brenner, B., Corbridge, T. C. & Kazzi, A., Aug 1 2009, In : Journal of Emergency Medicine. 37, 2 SUPPL.

Research output: Contribution to journalArticle

14 Scopus citations

Isoforms of vitamin E have opposing immunoregulatory functions during inflammation by regulating leukocyte recruitment

Berdnikovs, S., Abdala-Valencia, H., McCary, C., Somand, M., Cole, R., Garcia, A., Bryce, P. & Cook-Mills, J. M., Apr 1 2009, In : Journal of Immunology. 182, 7, p. 4395-4405 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

Issues associated with assessing nuclear localization of N-terminally unphosphorylated β-catenin with monoclonal antibody 8E7

Maher, M. T., Flozak, A. S., Hartsell, A. M., Russell, S., Beri, R., Peled, O. N. & Gottardi, C. J., Feb 2 2009, In : Biology Direct. 4, 5.

Research output: Contribution to journalArticle

19 Scopus citations

Keratinocyte growth factor expression is suppressed in early acute lung injury/acute respiratory distress syndrome by smad and c-Abl pathways

Chandel, N. S., Budinger, G. R. S., Mutlu, G. M., Varga, J., Synenki, L., Donnelly, H. K., Zirk, A., Eisenbart, J., Jovanovic, B. & Jain, M., May 2009, In : Critical care medicine. 37, 5, p. 1678-1684 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution

Soberanes, S., Urich, D., Baker, C. M., Burgess, Z., Chiarella, S. E., Bell, E. L., Ghio, A. J., De Vizcaya-Ruiz, A., Liu, J., Ridge, K. M., Kamp, D. W., Chandel, N. S., Schumacker, P. T., Mutlu, G. M. & Budinger, G. R. S., Jan 23 2009, In : Journal of Biological Chemistry. 284, 4, p. 2176-2186 11 p.

Research output: Contribution to journalArticle

97 Scopus citations

Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-α-induced JNK1 activation

Liu, J., Zhao, Y., Eilers, M. & Lin, A., 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 43, p. 18279-18284 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Myosin-Va restrains the trafficking of Na+/K+-ATPase-containing vesicles in alveolar epithelial cells

Lecuona, E., Minin, A., Trejo, H. E., Chen, J., Comellas, A. P., Sun, H., Grillo, D., Nekrasova, O. E., Welch, L. C., Szleifer, I., Gelfand, V. I. & Sznajder, J. I., 2009, In : Journal of cell science. 122, 21, p. 3915-3922 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members

Snyder, C. M., Shroff, E. H., Liu, J. & Chandel, N. S., Sep 21 2009, In : PloS one. 4, 9, e7059.

Research output: Contribution to journalArticle

69 Scopus citations

Noninvasive ventilation

Nowak, R., Corbridge, T. & Brenner, B., Aug 1 2009, In : Journal of Allergy and Clinical Immunology. 124, 2 SUPPL.

Research output: Contribution to journalArticle

6 Scopus citations

Noninvasive ventilation

Nowak, R., Corbridge, T. & Brenner, B., Aug 1 2009, In : Proceedings of the American Thoracic Society. 6, 4, p. 367-370 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Noninvasive Ventilation

Nowak, R., Corbridge, T. & Brenner, B., Aug 1 2009, In : Journal of Emergency Medicine. 37, 2 SUPPL.

Research output: Contribution to journalArticle

2 Scopus citations

Novel swine-origin (S-OIV) H1N1 influenza a pneumonia in a lung transplant patient: A case report and review of the literature on performance characteristics of rapid screening tests for the S-OIV

Raj, R., Cerdan, M., Yepeshurtado, A., Kimbrough, R. & Nugent, K., Dec 2009, In : American Journal of the Medical Sciences. 338, 6, p. 506-508 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Obesity-asthma association: Is it explained by systemic oxidant stress?

Sood, A., Qualls, C., Arynchyn, A., Beckett, W. S., Gross, M. D., Steffes, M. W., Smith, L. J., Holvoet, P., Thyagarajan, B. & Jacobs, D. R., Oct 1 2009, In : CHEST. 136, 4, p. 1055-1062 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

One hundred-foot walk test for functional assessment of clinic patients

Raj, R., Guerra, D., Sehli, S., Nipp, R., Perdue, N., Alalawi, R., Jager, L. & Nugent, K., Nov 2009, In : American Journal of the Medical Sciences. 338, 5, p. 361-367 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

PIRO score for community-acquired pneumonia: A new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia

Rello, J., Rodriguez, A., Lisboa, T., Gallego, M., Lujan, M. & Wunderink, R., Feb 2009, In : Critical care medicine. 37, 2, p. 456-462 7 p.

Research output: Contribution to journalArticle

114 Scopus citations

Potential reasons why physicians underuse ung-protective ventilation: A retrospective cohort study using physician documentation

Mikkelsen, M. E., Dedhiya, P. M., Kalhan, R., Gallop, R. J., Lanken, P. N. & Fuchs, B. D., Apr 2009, In : Respiratory care. 53, 4, p. 455-461 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Proapoptotic Noxa is required for particulate matterinduced cell death and lung inflammation

Urich, D., Soberanes, S., Burgess, Z., Chiarella, S. E., Ghio, A. J., Ridge, K. M., Kamp, D. W., Chandel, N. S., Mutlu, G. M. & Budinger, G. R. S., Jul 2009, In : FASEB Journal. 23, 7, p. 2055-2064 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Pulmonary complications of inflammatory bowel disease: focus on management issues

Moon, E., Gillespie, C. T. & Vachani, A., Jul 1 2009, In : Techniques in Gastrointestinal Endoscopy. 11, 3, p. 127-139 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pulmonary Complications of Inflammatory Bowel Disease: focus on Management Issues.

Moon, E., Gillespie, C. & Vachani, A., Jul 2009, In : Techniques in Gastrointestinal Endoscopy.. 11, 3, p. 127 1 p.

Research output: Contribution to journalArticle

Recommendations for the management and follow-up of asthma exacerbations. Introduction.

Schatz, M., Kazzi, A. A. N., Brenner, B., Camargo, C. A., Corbridge, T., Krishnan, J. A., Nowak, R. & Rachelefsky, G., Jan 1 2009, In : The Journal of emergency medicine. 37, 2 Suppl

Research output: Contribution to journalArticle

1 Scopus citations

Respiratory infections: A current and future threat Series

Waterer, G. & Wunderink, R., Jul 2009, In : Respirology. 14, 5, p. 651-655 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis

Panduri, V., Liu, G., Surapureddi, S., Kondapalli, J., Soberanes, S., de Souza-Pinto, N. C., Bohr, V. A., Budinger, G. R. S., Schumacker, P. T., Weitzman, S. A. & Kamp, D. W., Sep 15 2009, In : Free Radical Biology and Medicine. 47, 6, p. 750-759 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

Sensing, physiological effects and molecular response to elevated CO2 levels in eukaryotes

Sharabi, K., Lecuona, E., Helenius, I. T., Beitel, G. J., Sznajder, J. I. & Gruenbaum, Y., Nov 2009, In : Journal of Cellular and Molecular Medicine. 13, 11-12, p. 4304-4318 15 p.

Research output: Contribution to journalArticle

31 Scopus citations

Severe adverse drug reaction to gadobenate dimeglumine

Singer, B. D., Woodrick, R. S. & Pedicano, J. B., May 22 2009, In : TheScientificWorldJournal. 9, p. 363-365 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Shear stress induced reorganization of the keratin intermediate filament network requires phosphorylation by protein kinase C ζ

Sivaramakrishnan, S., Schneider, J. L., Sitikov, A., Goldman, R. D. & Ridge, K. M., Jun 1 2009, In : Molecular biology of the cell. 20, 11, p. 2755-2765 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

Short-term placement of multiple self-expandable metallic stents for the treatment of bilateral bronchial dehiscences complicating lung transplantation

Tor, M., Musani, A. I., Gillespie, C., Leh, S., Kotloff, R. & Sterman, D. H., Jan 1 2009, In : Journal of Bronchology and Interventional Pulmonology. 16, 1, p. 63-65 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Studies in mice deficient for the autoimmune regulator (Aire) and transgenic for the thyrotropin receptor reveal a role for Aire in tolerance for thyroid autoantigens

Misharin, A. V., Nagayama, Y., Aliesky, H. A., Rapoport, B. & McLachlan, S. M., Jun 2009, In : Endocrinology. 150, 6, p. 2948-2956 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Targeting transcription factor NFκB: Comparative analysis of proteasome and IKK inhibitors

Gasparian, A. V., Guryanova, O. A., Chebotaev, D. V., Shishkin, A. A., Yemelyanov, A. Y. & Budunova, I. V., May 15 2009, In : Cell Cycle. 8, 10, p. 1559-1566 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

The dynamic properties of intermediate filaments during organelle transport

Chang, L., Barlan, K., Chou, Y. H., Grin, B., Lakonishok, M., Serpinskaya, A. S., Shumaker, D. K., Herrmann, H., Gelfand, V. I. & Goldman, R. D., Aug 15 2009, In : Journal of cell science. 122, 16, p. 2914-2923 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

The terminal region of β-catenin promotes stability by shielding the armadillo repeats from the axin-scaffold destruction complex

Mo, R., Chew, T. L., Maher, M. T., Bellipanni, G., Weinberg, E. S. & Gottardi, C. J., Oct 9 2009, In : Journal of Biological Chemistry. 284, 41, p. 28222-28231 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Thyroid antigens, not central tolerance, control responses to immunization in BALB/c versus C57BL/6 mice.

Misharin, A. V., Rapoport, B. & McLachlan, S. M., May 2009, In : Thyroid : official journal of the American Thyroid Association. 19, 5, p. 503-509 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Tubulin acetylation and histone deacetylase 6 activity in the lung under cyclic load

Geiger, R. C., Kaufman, C. D., Lam, A. P., Budinger, G. R. S. & Dean, D. A., Jan 1 2009, In : American journal of respiratory cell and molecular biology. 40, 1, p. 76-82 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Ubiquitination participates in the lysosomal degradation of Na,K-ATPase in steady-state conditions

Lecuona, E., Sun, H., Vohwinkel, C., Ciechanover, A. & Sznajder, J. I., Dec 1 2009, In : American journal of respiratory cell and molecular biology. 41, 6, p. 671-679 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Utility of [18F]2-fluoro-2-deoxyglucose-PET in sporadic and tuberous sclerosis-associated lymphangioleiomyomatosis

Young, L. R., Franz, D. N., Nagarkatte, P., Fletcher, C. D. M., Wikenheiser-Brokamp, K. A., Galsky, M. D., Corbridge, T. C., Lam, A. P., Gelfand, M. J. & McCormack, F. X., Sep 1 2009, In : CHEST. 136, 3, p. 926-933 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Vitamin D deficiency modulates graves' hyperthyroidism induced in BALB/c mice by thyrotropin receptor immunization

Misharin, A., Hewison, M., Chen, C. R., Lagishetty, V., Aliesky, H. A., Mizutori, Y., Rapoport, B. & McLachlan, S. M., Feb 2009, In : Endocrinology. 150, 2, p. 1051-1060 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

α1-AMP-activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase Cζ

Gusarova, G. A., Dada, L. A., Kelly, A. M., Brodie, C., Witters, L. A., Chandel, N. S. & Sznajder, J. I., Jul 2009, In : Molecular and cellular biology. 29, 13, p. 3455-3464 10 p.

Research output: Contribution to journalArticle

77 Scopus citations
2008

A 23-year-old woman with sudden-onset dyspnea and chest pain penetrating to the back

Kwon, J. S., Blum, M. G. & Kalhan, R., Jan 1 2008, In : Chest. 133, 2, p. 574-578 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation

Lin, X., David, C. A., Donnelly, J. B., Michaelides, M., Chandel, N. S., Huang, X., Warrior, U., Weinberg, F., Tormos, K. V., Fesik, S. W. & Shen, Y., Jan 8 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 1, p. 174-179 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome

Morris, P. E., Papadakos, P., Russell, J. A., Wunderink, R., Schuster, D. P., Truwit, J. D., Vincent, J. L. & Bernard, G. R., Mar 2008, In : Critical care medicine. 36, 3, p. 782-788 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung

Taranova, A. G., Maldonado, D., Vachon, C. M., Jacobsen, E. A., Abdala-Valencia, H., McGarry, M. P., Ochkur, S. I., Protheroe, C. A., Doyle, A., Grant, C. S., Cook-Mills, J., Birnbaumer, L., Lee, N. A. & Lee, J. J., Oct 15 2008, In : Cancer Research. 68, 20, p. 8582-8589 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

A mechanism of benefit of soy genistein in asthma: Inhibition of eosinophil p38-dependent leukotriene synthesis

Kalhan, R., Smith, L. J., Nlend, M. C., Nair, A., Hixon, J. L. & Sporn, P. H. S., Jan 2008, In : Clinical and Experimental Allergy. 38, 1, p. 103-112 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

Vadász, I., Dada, L. A., Briva, A., Trejo, H. E., Welch, L. C., Chen, J., Tóth, P. T., Lecuona, E., Witters, L. A., Schumacker, P. T., Chandel, N. S., Seeger, W. & Sznajder, J. I., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 752-762 11 p.

Research output: Contribution to journalArticle

115 Scopus citations