Medicine, Pulmonary Division

Research Output 1949 2019

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Comment/debate
2019

Erratum: Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis (Cell Metabolism (2019) 29(2) (335–347.e5), (S1550413118305862) (10.1016/j.cmet.2018.09.019))

Soberanes, S., Misharin, A., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C. I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 others, Jain, M., Perlman, H. R., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N., Mutlu, G. M. & Budinger, GR. S., Feb 5 2019, In : Cell Metabolism. 29, 2, 1 p.

Research output: Contribution to journalComment/debate

Metformin
Air Pollution
Electron Transport
Names
Publications

Probing mitochondrial metabolism in vivo

McElroy, G. S. & Chandel, N., Jan 2 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 1, p. 20-22 3 p.

Research output: Contribution to journalComment/debate

Mitochondria
2018

Erratum for Drusano et al., "Dilution Factor of Quantitative Bacterial Cultures Obtained by Bronchoalveolar Lavage in Patients with Ventilator-Associated Bacterial Pneumonia"

Drusano, G. L., Corrado, M. L., Girardi, G., Ellis-Grosse, E. J., Wunderink, R. G., Donnelly, H., Leeper, K. V., Brown, M., Malek, T., Hite, R. D., Ferrari, M., Djureinovic, D., Kollef, M. H., Mayfield, L., Doyle, A., Chastre, J., Combes, A., Walsh, T. J., Dorizas, K., Alnuaimat, H. & 13 others, Morgan, B. E., Rello, J., Mazo, C. A., Jones, R. N., Flamm, R. K., Woosley, L., Ambrose, P. G., Bhavnani, S., Rubino, C. M., Bulik, C. C., Louie, A., Vicchiarelli, M. & Berman, C., Apr 1 2018, In : Antimicrobial agents and chemotherapy. 62, 4

Research output: Contribution to journalComment/debate

Open Access
Bacterial Pneumonia
Ventilator-Associated Pneumonia
Bronchoalveolar Lavage
1 Citation (Scopus)

Mitochondria: Back to the future

Chandel, N., Jan 23 2018, In : Nature Reviews Molecular Cell Biology. 19, 2, 1 p.

Research output: Contribution to journalComment/debate

Mitochondria

Sequestration of mitochondrial iron by silica particle initiates a biological effect (Am J Physiol Lung Cell Mol Physiol, 305, (L712-L724), (2013), 10.1152/ajplung.00099.2013)

Ghio, A. J., Tong, H., Soukup, J., Dailey, L. A., Cheng, W., Samet, J. M., Kesic, M. J., Bromberg, P. A., Turi, J. L., Upadhyay, D., Budinger, GR. S. & Mutlu, G. M., Nov 1 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 5, p. L919

Research output: Contribution to journalComment/debate

Silicon Dioxide
Iron
Lung
ammonium ferric sulfate
ferric ammonium citrate
2017

Erratum: Removal notice to (617) – Candida Colonization Is Associated with Improved Survival After Lung Transplant (J Heart Lung Transplant (2017) 36(4) (S238) (S1053249817306368) (10.1016/j.healun.2017.01.629))

Green, J. S., Brown, R., Umeda, T., Rudser, K., Elde, S., Roberts, J. M., Hertz, M. I., Loor, G., Young, J. H. & Tomic, R., Aug 1 2017, In : Journal of Heart and Lung Transplantation. 36, 8, 1 p.

Research output: Contribution to journalComment/debate

Candida
Transplants
Lung
Publications
1 Citation (Scopus)

Metastatic pulmonary calcification and end-stage renal disease

Walter, J. M., Stanley, M. V. N. & Singer, B., Sep 1 2017, In : Cleveland Clinic Journal of Medicine. 84, 9, p. 668-669 2 p.

Research output: Contribution to journalComment/debate

Chronic Kidney Failure
Lung

Searching for Staircases: Strengthening the Connections Between the Emergency Department and the Intensive Care Unit

Walter, J. M. & Walter, J. J., Oct 1 2017, In : Academic Emergency Medicine. 24, 10, p. 1281-1282 2 p.

Research output: Contribution to journalComment/debate

Intensive Care Units
Hospital Emergency Service
5 Citations (Scopus)

Sequelae of donor-derived mollicutes transmission in lung recipients

Fernandez, R., Chi, M., Ison, M. G., Waites, K. B., Crabb, D. M., Ratliff, A. E., Cajigas, H. R., DeCamp Jr, M. M., Odell, D. D., Budinger, GR. S. & Bharat, A., Mar 1 2017, In : American journal of respiratory and critical care medicine. 195, 5, p. 687-689 3 p.

Research output: Contribution to journalComment/debate

Tenericutes
Lung
2016

Air in the left ventricle: An unusual case of Endocarditis

Kesler, S., Kim, H., Perlman, D., Dincer, H. E., Thenappan, T. & Tomic, R., May 15 2016, In : American Journal of Respiratory and Critical Care Medicine. 193, 10, p. 1176-1177 2 p.

Research output: Contribution to journalComment/debate

Endocarditis
Heart Ventricles
Air

Disappearing post-pneumonectomy pleural fluid without bronchopleural fistula

Smith, D. A., Gillespie, C. T., DeCamp Jr, M. M. & Bharat, A., Apr 15 2016, In : American journal of respiratory and critical care medicine. 193, 8, p. 925-926 2 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Erratum: Immunological Priming Requires Regulatory T Cells and IL-10 -Producing Macrophages To Accelerate Resolution from Severe Lung Inflammation (Journal of Immunology (2014) 192 (4453-4464))

Aggarwalx, N. R., Tsushima, K., Eto, Y., Tripathi, A., Mandke, P., Mock, J. R., Garibaldi, B. T., Singer, B. D., Sidhaye, V. K., Horton, M. R., King, L. S. & D'Alessio, F. R., May 1 2016, In : Journal of Immunology. 196, 9, p. 3963-3964 2 p.

Research output: Contribution to journalComment/debate

Regulatory T-Lymphocytes
Allergy and Immunology
Interleukin-10
Pneumonia
Macrophages

Transcriptomic signatures decode Th17 cell pathogenicity

Reyfman, P. A., Bartom, E. T. & Singer, B., Sep 1 2016, In : Cellular and Molecular Immunology. 13, 5, p. 557-559 3 p.

Research output: Contribution to journalComment/debate

Th17 Cells
Virulence

Wandering pleural mesothelial fatty cyst

Nicholson, T. T., Raparia, K., Mutlu, G. M., Sporn, P. H. S. & Bharat, A., Nov 1 2016, In : American journal of respiratory and critical care medicine. 194, 9, p. 1164-1165 2 p.

Research output: Contribution to journalComment/debate

Cysts

What is pneumonia?

Jones, B., Dean, N., Wunderink, R. & Sockrider, M., Jan 1 2016, In : American Journal of Respiratory and Critical Care Medicine. 193, 1, p. P1-P2

Research output: Contribution to journalComment/debate

Bacterial Pneumonia
Pneumonia
Anti-Bacterial Agents
2015
3 Citations (Scopus)

CAP death: What goes wrong when everything is right?

Wunderink, R. G., Sep 1 2015, In : The Lancet Infectious Diseases. 15, 9, p. 995-996 2 p.

Research output: Contribution to journalComment/debate

Bacterial Pneumonia
Anti-Bacterial Agents
3 Citations (Scopus)

Corrigendum: [The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation (Nat. Immunol.) (2015) 16:458'466]

Zhang, Q., Kuang, H., Chen, C., Yan, J., Do-Umehara, H. C., Liu, X. Y., Dada, L., Ridge, K. M., Chandel, N. S. & Liu, J., Jul 20 2015, In : Nature Immunology. 16, 7, 1 p.

Research output: Contribution to journalComment/debate

Mitochondrial Degradation
Phosphotransferases
Neoplasms
corrigendum
Adrenergic Agents
corrigendum
sodium-translocating ATPase
Calcium Release Activated Calcium Channels
2014
3 Citations (Scopus)
Antineoplastic Combined Chemotherapy Protocols
Muscle Weakness
Vincristine
Prednisone
Diaphragm

Community-acquired pneumonia.

Wunderink, R. G. & Waterer, G. W., Jan 1 2014, In : The New England journal of medicine. 370, 19, 1 p.

Research output: Contribution to journalComment/debate

Pneumonia
Anti-Bacterial Agents

Invited commentary

Bhorade, S., Jan 1 2014, In : Annals of Thoracic Surgery. 97, 1, p. 274-275 2 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Regulatory T cell Itch reins in Th2 inflammation

Singer, B. D. & D'alessio, F. R., Jan 1 2014, In : Cellular and Molecular Immunology. 11, 2, p. 126-128 3 p.

Research output: Contribution to journalComment/debate

Th2 Cells
Ubiquitin-Protein Ligases
Regulatory T-Lymphocytes
Inflammation

Reply: antioxidants in the intensive care unit.

Jain, M. & Chandel, N. S., Jan 1 2014, In : American Journal of Respiratory and Critical Care Medicine. 189, 8, 1 p.

Research output: Contribution to journalComment/debate

Critical Illness
Intensive Care Units
Reactive Oxygen Species
Oxidative Stress
Antioxidants

Stem cell energetics

Passegue, E., Teitell, M., Ding, S., Rando, T., Belmonte, J. C. I., Ramalho-Santos, M., Terzic, A., Brunet, A., Chandel, N., Bonnet, D. & Jasper, H., Dec 2 2014, In : Cell Metabolism. 20, 6, p. 922-925 4 p.

Research output: Contribution to journalComment/debate

2013

Erratum: PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo (Journal of Immunology (2012) 188 (874-884))

Berdnikovs, S., Pavlov, V. I., Abdala-Valencia, H., McCary, C. A., Chan, J., Klumpp, D. J., Tremblay, M. L. & Cook-Mills, J. M., Mar 15 2013, In : Journal of Immunology. 190, 6, 1 p.

Research output: Contribution to journalComment/debate

Allergy and Immunology
Leukocytes
Inflammation
1 Citation (Scopus)

Erratum: A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension (Journal of Biological Chemistry (2013) 288 (25701-25716))

Patel, M., Predescu, D., Tandon, R., Bardita, C., Pogoriler, J., Bhorade, S., Wang, M., Comhair, S., Ryan-Hemnes, A., Chen, J., Machado, R., Husain, A., Erzurum, S. & Predescu, S., Dec 27 2013, In : Journal of Biological Chemistry. 288, 52, 1 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)

Erratum to Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer [Cancer Cell 24, (2004) 213-228]

Patra, K. C., Wang, Q., Bhaskar, P. T., Miller, L., Wang, Z., Wheaton, W., Chandel, N., Laakso, M., Muller, W. J., Allen, E. L., Jha, A. K., Smolen, G. A., Clasquin, M. F., Robey, R. B. & Hay, N., Sep 9 2013, In : Cancer Cell. 24, 3, 1 p.

Research output: Contribution to journalComment/debate

Hexokinase
Maintenance
Neoplasms
Therapeutics
9 Citations (Scopus)

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis [Immunity 38 (2013) 79-91]

Yona, S., Kim, K. W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., Hume, D., Perlman, H., Malissen, B., Zelzer, E. & Jung, S., May 23 2013, In : Immunity. 38, 5, p. 1073-1079 7 p.

Research output: Contribution to journalComment/debate

ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours (Biochemical Journal (2013) 451, (395-405))

Campos, M. L., Sánchez-Arévalo Lobo, V. J., Rodolosse, A., Gottardi, C. J., Mafficini, A., Beghelli, S., Scardoni, M., Bassi, C., Scarpa, A. & Real, F. X., Jul 1 2013, In : Biochemical Journal. 453, 1, 1 p.

Research output: Contribution to journalComment/debate

Neoplasms
6 Citations (Scopus)

Lung microbiota: Genuine or artifact?

Berger, G. & Wunderink, R. G., Dec 1 2013, In : Israel Medical Association Journal. 15, 12, p. 731-733 3 p.

Research output: Contribution to journalComment/debate

Specimen Handling
Respiratory Tract Diseases
Microbiota
Bronchoscopy
Sputum

Rebuttal from Dr Wolfe.

Wolfe, L. F., May 1 2013, In : Chest. 143, 5, 1 p.

Research output: Contribution to journalComment/debate

Electric Stimulation Therapy
Phrenic Nerve
Spinal Cord Injuries
4 Citations (Scopus)

Revealing the complexity of chronic obstructive pulmonary disease

Vermylen, J. & Kalhan, R., Jan 1 2013, In : Translational Research. 162, 4, p. 203-207 5 p.

Research output: Contribution to journalComment/debate

Chronic Obstructive Pulmonary Disease
40 Citations (Scopus)

The Proto-oncometabolite Fumarate Binds Glutathione to amplify ROS-dependent signaling

Sullivan, L., Martinez-Garcia, E., Nguyen, H., Mullen, A., Dufour, E., Sudarshan, S., Licht, J., Deberardinis, R. & Chandel, N., Jul 25 2013, In : Molecular Cell. 51, 2, 1 p.

Research output: Contribution to journalComment/debate

2012
9 Citations (Scopus)

Methicillin-resistant staphylococcus aureus and community-acquired pneumonia: An evolving relationship

Mandell, L. A. & Wunderink, R. G., Apr 15 2012, In : Clinical Infectious Diseases. 54, 8, p. 1134-1136 3 p.

Research output: Contribution to journalComment/debate

Staphylococcal Pneumonia
Community-Acquired Infections
Methicillin-Resistant Staphylococcus aureus
Pneumonia
Incidence
1 Citation (Scopus)

MUC5B and pulmonary fibrosis, omalizumab for severe allergic asthma, and interstitial lung abnormalities in smokers with emphysema

Chandra, D., Coleman, J. M., Herazo-Maya, J. D. & Kreit, J. W., May 1 2012, In : American Journal of Respiratory and Critical Care Medicine. 185, 9, p. 1021-1022 2 p.

Research output: Contribution to journalComment/debate

Pulmonary Fibrosis
Emphysema
Asthma
Lung
Omalizumab

Warburg effect and redox balance (Science (2011) (1219))

Hamanaka, R. B. & Chandel, N. S., Jan 13 2012, In : Science. 335, 6065, 1 p.

Research output: Contribution to journalComment/debate

2011
36 Citations (Scopus)

Mitochondrial Ca2+ and ROS take center stage to orchestrate TNF-α-mediated inflammatory responses

Dada, L. & Sznajder, J. I., May 2 2011, In : Journal of Clinical Investigation. 121, 5, p. 1683-1685 3 p.

Research output: Contribution to journalComment/debate

Tumor Necrosis Factor Receptors
Microvessels
Endotoxins
Sepsis
Pneumonia
2010

Erratum: Asthma in Adolescents and Adults (American Journal of Nursing (2010) 110: 5 (28-38))

Corbridge, S. & Corbridge, T. C., Jun 1 2010, In : American Journal of Nursing. 110, 6, 1 p.

Research output: Contribution to journalComment/debate

Nursing
Asthma
4 Citations (Scopus)

Influenza and bacterial pneumonia - constant companions

Wunderink, R. G., May 13 2010, In : Critical Care. 14, 3, 150.

Research output: Contribution to journalComment/debate

Bacterial Pneumonia
Human Influenza
Pneumonia
Viral Pneumonia
Antiviral Agents

Isoforms of vitamin E have opposing immunoregulatory functions during inflammation by regulating leukocyte recruitment (The Journal of Immunology (2009) 182, (4395-4405))

Berdnikovs, S., Abdala-Valencia, H., McCary, C., Somand, M., Cole, R., Garcia, A., Bryce, P. & Cook-Mills, J. M., Jul 15 2010, In : Journal of Immunology. 185, 2, 1 p.

Research output: Contribution to journalComment/debate

Allergy and Immunology
Vitamin E
Protein Isoforms
Leukocytes
Inflammation
11 Citations (Scopus)
Coal Mining
Anthracosis
Silicosis
Occupational Diseases
Occupational Exposure
2008
4 Citations (Scopus)

Improving survival by increasing lung edema clearance: Is airspace delivery of dopamine a solution?

Jaitovich, A. & Sznajder, J. I., Apr 15 2008, In : Critical Care. 12, 2, 135.

Research output: Contribution to journalComment/debate

Dopamine
Edema
Lung
Survival
Active Biological Transport
2007
2 Citations (Scopus)

Mycophenolate mofetil: A promising novel therapy in systemic sclerosis

Jain, M. & Varga, J., May 1 2007, In : Current Rheumatology Reports. 9, 2, p. 133-135 3 p.

Research output: Contribution to journalComment/debate

Mycophenolic Acid
Systemic Scleroderma
Therapeutics
2003
2 Citations (Scopus)

Erratum: High-dose, short-course levofloxacin for community-acquired pneumonia: A new treatment paradigm (Clinical Infectious Diseases (2003) 37 (752-60))

Dunbar, L. M., Wunderink, R. G., Habib, M. P., Smith, L. G., Tenneberg, A. M., Khashab, M. M., Wiesinger, B. A., Xiang, J. X., Zadeikis, N. & Kahn, J. B., Oct 15 2003, In : Clinical Infectious Diseases. 37, 8, 1 p.

Research output: Contribution to journalComment/debate

Levofloxacin
Communicable Diseases
Pneumonia
2001

Increased prevalence of gastroesophageal reflux symptoms in patients with COPD

Mokhlesi, B., Morris, A. L., Huang, C. F., Curcio, A. J., Barrett, T. A. & Kamp, D. W., Jan 1 2001, In : Revista Portuguesa de Pneumologia. 7, 4-5, p. 400-402 3 p.

Research output: Contribution to journalComment/debate

Gastroesophageal Reflux
Chronic Obstructive Pulmonary Disease
Asthma
1998
30 Citations (Scopus)
Ventilator-Associated Pneumonia
Artificial Respiration
Pneumonia
Research Design
Sensitivity and Specificity
1993
68 Citations (Scopus)

Delivery of Na+,K(+)-ATPase in polarized epithelial cells.

Gottardi, C. J. & Caplan, M. J., Apr 23 1993, In : Science. 260, 5107, p. 552-554 3 p.

Research output: Contribution to journalComment/debate

Sodium-Potassium-Exchanging ATPase
Cell Polarity
Epithelial Cells
Cell Membrane
Dogs
37 Citations (Scopus)

Delivery of Na+,K+-ATPase in polarized epithelial cells

Zurzolo, C., Rodriguez-Boulan, E., Gottardi, C. J., Caplan, M. J., Siemers, K. A., Wilson, R., Mays, R. W., Ryan, T. A., Wollner, D. A. & Nelson, W. J., Jan 1 1993, In : Science. 260, 5107, p. 550-556 7 p.

Research output: Contribution to journalComment/debate

Sodium-Potassium-Exchanging ATPase
Cell Polarity
Epithelial Cells
Cell Membrane
Cell Line
Proton-Translocating ATPases
Adenosine Triphosphatases
Ions
Proteins
sodium-translocating ATPase

Questions and answers

Lewis, J. M., Garfin, S. R., Cohen, M. S., Carter, C. L., Coon, W. W., Cugell, D. W., Dieter, R. A., Ellyn, G., Mason, R. P. & Besdine, R. W., Oct 25 1993, In : Journal of the American Medical Association. 270, 15, p. 1867-1868 2 p.

Research output: Contribution to journalComment/debate