Medicine, Rheumatology Division

Grants

Grants per year 1993 2002 2007 2008 2010 2011 2013 2014 2015 2016 2017 2018 2019 2020 2021 2027

• 1 Not started
• 80 Active
• 354 Finished

Grants per year

Search results

• Research project

  Pathogenic Wnt-beta catenin target genes in macrophages and fibrosis

  Gottardi, C., Misharin, A., Tetreault, M. & Winter, D. R.

  Yale University, National Institute of Arthritis and Musculoskeletal and Skin Diseases

  7/3/19 → 6/30/22

  Project: Research project

• Aberrant Recapitulation of Developmental Program: Novel Target in Scleroderma

  Varga, J., Gottardi, C., Hinchcliff, M. E. & Wei, J.

  U.S. Army Medical Research and Materiel Command

  9/30/12 → 3/31/16

  Project: Research project

• Synovial Macrophage Transcriptional Signatures for Predicting Therapeutic Efficacy

  Perlman, H. R., Lee, Y. C., Mandelin, A. M., Muhammad, L. N., Wehbe, F., Winter, D. R. & Cuda, C. M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/18/19 → 7/31/24

  Project: Research project

  • Rheumatoid Arthritis 100%
  • Macrophages 73%
  • Biopsy 44%
  • Antirheumatic Agents 43%
  • RNA Sequence Analysis 40%

• Macrophage Heterogeneity in Rheumatoid Arthritis

  Perlman, H. R., Winter, D. R., Cuda, C. M., Lee, Y. C., Mandelin, A. M. & Muhammad, L. N.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  4/15/22 → 2/28/27

  Project: Research project

  • Macrophages 100%
  • Rheumatoid Arthritis 76%
  • Joints 39%
  • Arthritis 24%
  • Transcription Factors 15%

• Donor nonclassical monocytes initiate lung injury following transplantation

  Bharat, A., Misharin, A., Stehlik, C., Winter, D. R. & Wu, Q.

  National Heart, Lung, and Blood Institute

  1/1/19 → 12/31/23

  Project: Research project

  • Monocytes 100%
  • Primary Graft Dysfunction 76%
  • Lung Injury 68%
  • Tissue Donors 61%
  • Transplantation 56%

• Role of CCR7 in Clinical Response in Inflammatory Arthritis

  Pope, R. M., Huang, Q. & Perlman, H. R.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  7/1/13 → 6/30/16

  Project: Research project

• Measuring Gene Expression in the Skin: Novel Biomarkers for Scleroderma

  Hinchcliff, M. E.

  Scleroderma Foundation

  1/1/11 → 12/31/13

  Project: Research project

• Mining genomic data to develop novel therapeutics for systemic sclerosis

  Hinchcliff, M. E.

  Dartmouth College, Dr. Ralph and Marian Falk Medical Research Trust

  11/30/14 → 11/30/15

  Project: Research project

  • Data Mining 100%
  • Systemic Scleroderma 94%
  • Gene expression 45%
  • Patient Rights 44%
  • Pharmaceutical Preparations 34%

• Molecular Mechanisms of Cytoskeletal Rearrangement in Rheumatoid Arthritis

  Dorfleutner, A.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  7/17/09 → 6/30/11

  Project: Research project

• Medical and Graduate Student Preceptorship-Aileen Hoffmann

  Hinchcliff, M. E.

  Rheumatology Research Foundation

  5/21/18 → 7/31/18

  Project: Research project

  • Preceptorship 100%
  • Medical Students 65%
  • Systemic Scleroderma 50%
  • Interstitial Lung Diseases 48%
  • Rheumatology 47%

• The trajectory of pulmonary function tests in patients with systemic sclerosis

  Hinchcliff, M. E.

  Rheumatology Research Foundation

  10/1/17 → 3/29/19

  Project: Research project

  • Systemic Scleroderma 100%
  • Respiratory Function Tests 56%
  • Interstitial Lung Diseases 46%
  • Vital Capacity 22%
  • Lung 22%

• PHAROS Pulmonary Hypertension Study

  Hinchcliff, M. E.

  Georgetown University, Scleroderma Foundation

  7/1/07 → 7/2/08

  Project: Research project

• The Role of AFAP1 in Breast Cancer Metastasis

  Dorfleutner, A.

  Concern Foundation

  7/1/10 → 6/30/13

  Project: Research project

• Novel pathways of fibrosis: targeting cyclin-dependent kinase

  Wei, J. & Hinchcliff, M. E.

  Scleroderma Foundation

  1/15/13 → 12/31/15

  Project: Research project

  • Systemic Scleroderma 100%
  • Cyclin-Dependent Kinases 76%
  • Fibrosis 65%
  • Fibroblasts 48%
  • PPAR gamma 48%

• Molecular Mechanisms of Cytoskeletal Rearrangement in Rheumatoid Arthritis

  Dorfleutner, A.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  7/1/11 → 6/30/13

  Project: Research project

  • Actin Cytoskeleton 100%
  • Rheumatoid Arthritis 83%
  • Fibroblasts 46%
  • Proteins 32%
  • Actins 32%

• LCTC Network Participation - To Identify Promising New Therapies for Systemic Lupus Erythematosus and to Encourage Testing of those Therapies by Clinical Trial Sponsors

  Ramsey-Goldman, R.

  Lupus Clinical Trials Consortium

  1/15/04 → 6/30/07

  Project: Research project

• Prot #XmAb5871-04: A Randomized, Double-Blinded, Placebo-Controlled Study of the Effect of XmAb®5871 on Systemic Lupus Erythematosus Disease Activity

  Ramsey-Goldman, R.

  PPD Investigator Services, LLC, Xencor, Inc.

  9/13/16 → 9/13/19

  Project: Research project

• Prot# LBSL02: A Phs 2, Mlti-Cntr, Dbl-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety, Tolerability, & Efficacy of LymphoStat-B? Antibody (Monoclonal Anti-BLyS Antibody) in Subjects w/Systemic Lupus Erythematosus (SLE)

  Ramsey-Goldman, R.

  Human Genome Sciences, Inc.

  11/14/03 → 8/21/10

  Project: Research project

• Prot# WA17043/U2644g: A Randomized, Multifactorial, Double-Blind, Parallel-Group, Dose-Ranging Study of the Efficacy and Safety of Rituximab (Mabthera®/Rituxan®) In Combination with Methotrexate in Patients with Active Rheumatoid Arthritis

  Ruderman, E. M.

  Genentech, Inc.

  7/11/03 → 6/1/07

  Project: Research project

• Prot# GL02-01: A Randomized, Double-Blind, Multi-Center, Placebo Controlled Study to Assess Prevention of Bone Loss by Treatment with Gl701 (Prestara?) in Women with Systemic Lupus Erythematosus Receiving Treatment with Glucocorticoids

  Ramsey-Goldman, R.

  Genelabs Technologies, Inc.

  1/31/03 → 8/21/10

  Project: Research project

• Adiponectin peptidomimetics: Noval therapy for scleroderma

  Varga, J. & Goncalves Marangoni, R.

  Bristol-Myers Squibb Company

  8/19/15 → 12/31/17

  Project: Research project

  • Systemic Scleroderma 100%
  • Peptidomimetics 73%
  • Adiponectin 53%
  • Fibrosis 18%
  • Connective Tissue Diseases 15%

• Molecular regulation of the systemic inflammatory response

  Stehlik, C.

  American Heart Association Midwest Affiliate

  7/1/13 → 12/31/15

  Project: Research project

  • Inflammasomes 100%
  • Septic Shock 28%
  • Sepsis 22%
  • Macrophages 19%
  • Cytokines 17%

• Postdoctoral Fellowship for Sonal Khare in Support of: POP3: A Novel Inhibitor of Inflammatory Arthritis

  Stehlik, C. & Khare, S.

  Arthritis Foundation

  9/1/12 → 8/31/13

  Project: Research project

• Community Programs to Improve Minority Health Grant Program (Fellows Project)

  Ramsey-Goldman, R.

  Lupus Research Institute, Inc., Department of Health and Human Services

  9/1/14 → 8/31/15

  Project: Research project

  • medicine 100%
  • emergency care 95%
  • grant 91%
  • minority 75%
  • assistant 63%

• Summer Clinical Research Training for Medical Students

  Ramsey-Goldman, R.

  American Federation for Medical Research

  6/1/08 → 8/31/08

  Project: Research project