Mesulam Center for Cognitive Neurology and Alzheimers Disease

2024

Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer’s disease and aging

Paudel, B., Jeong, S. Y., Martinez, C. P., Rickman, A., Haluck-Kangas, A., Bartom, E. T., Fredriksen, K., Affaneh, A., Kessler, J. A., Mazzulli, J. R., Murmann, A. E., Rogalski, E., Geula, C., Ferreira, A., Heckmann, B. L., Green, D. R., Sadleir, K. R., Vassar, R. & Peter, M. E., Dec 2024, In: Nature communications. 15, 1, 264.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Loss and microglia phagocytosis of synaptic proteins in frontotemporal lobar degeneration with TDP-43 proteinopathy

Ayala, I., Bahrami, A., Pan, Y., Spencer, C., Flanagan, M. E., Mesulam, M. M., Gefen, T. & Geula, C., May 2024, In: Neurochemistry International. 175, 105719.

Research output: Contribution to journal › Article › peer-review

Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias

Kawles, A., Keszycki, R., Minogue, G., Zouridakis, A., Ayala, I., Gill, N. P., Macomber, A., Lubbat, V., Coventry, C., Rogalski Miller, E. J., Weintraub, S., Mao, Q., Flanagan, M. E., Zhang, H., Castellani, R., Bigio, E. H., Mesulam, M. M., Geula, C. & Gefen, T., Dec 2024, In: Acta Neuropathologica Communications. 12, 1, 31.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Ancestry-related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk

Celis, K., Moreno, M. D. M. M., Rajabli, F., Whitehead, P., Hamilton-Nelson, K., Dykxhoorn, D. M., Nuytemans, K., Wang, L., Flanagan, M. E., Weintraub, S., Geula, C., Gearing, M., Dalgard, C. L., Jin, F., Bennett, D. A., Schuck, T., Pericak-Vance, M. A., Griswold, A. J., Young, J. I. & Vance, J. M., Sep 2023, In: Alzheimer's and Dementia. 19, 9, p. 3902-3915 14 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Differential vulnerability of the dentate gyrus to tauopathies in dementias

Kawles, A., Minogue, G., Zouridakis, A., Keszycki, R., Gill, N., Nassif, C., Coventry, C., Zhang, H., Rogalski, E., Flanagan, M. E., Castellani, R., Bigio, E. H., Mesulam, M. M., Geula, C. & Gefen, T., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 1.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Distinct and shared neuropsychiatric phenotypes in FTLD-tauopathies

Keszycki, R., Kawles, A., Minogue, G., Zouridakis, A., Macomber, A., Gill, N., Vu, M., Zhang, H., Coventry, C., Rogalski, E., Weintraub, S., Mesulam, M. M., Geula, C. & Gefen, T., 2023, In: Frontiers in Aging Neuroscience. 15, 1164581.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with Transactive Response DNA-binding Protein 43

Minogue, G., Kawles, A., Zouridakis, A., Keszycki, R., Macomber, A., Lubbat, V., Gill, N., Mao, Q., Flanagan, M. E., Zhang, H., Castellani, R., Bigio, E. H., Mesulam, M. M., Geula, C. & Gefen, T., Dec 2023, In: Annals of neurology. 94, 6, p. 1036-1047 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Evaluating the Association Between Genetically Proxied Neurodevelopmental Language Phenotypes and the Risk of Primary Progressive Aphasia

Nassan, M., Piras, I. S., Rogalski, E., Geula, C., Marsel Mesulam, M. & Huentelman, M., May 2 2023, In: Neurology. 100, 18, p. E1922-E1929

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Gaps in clinical research in frontotemporal dementia: A call for diversity and disparities–focused research

Franzen, S., Nuytemans, K., Bourdage, R., Caramelli, P., Ellajosyula, R., Finger, E., Illán-Gala, I., Loi, S. M., Morhardt, D., Pijnenburg, Y., Rascovsky, K., Williams, M. M., Yokoyama, J. S., Alladi, S., Ayhan, Y., Broce, I., Castro-Suarez, S., Coleman, K., de Souza, L. C. & Dacks, P. A. & 23 others, de Boer, S. C. M., de Leon, J., Dodge, S., Grasso, S., Gupta, V., Gupta, V., Ghoshal, N., Kamath, V., Kumfor, F., Matias-Guiu, J. A., Narme, P., Nielsen, T. R., Okhuevbie, D., Piña-Escudero, S. D., Garcia, R. R., Scarioni, M., Slachevsky, A., Suarez-Gonzalez, A., Tee, B. L., Tsoy, E., Ulugut, H., Babulal, G. M. & Onyike, C. U., Dec 2023, In: Alzheimer's and Dementia. 19, 12, p. 5817-5836 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma

Pang, L., Dunterman, M., Guo, S., Khan, F., Liu, Y., Taefi, E., Bahrami, A., Geula, C., Hsu, W. H., Horbinski, C., James, C. D. & Chen, P., Oct 2023, In: Nature Immunology. 24, 10, p. 1654-1670 17 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Shades of gray in human white matter

Zouridakis, A., Ayala, I., Minogue, G., Kawles, A., Keszycki, R., Macomber, A., Bigio, E. H., Geula, C., Mesulam, M. M. & Gefen, T., Dec 2023, In: Journal of Comparative Neurology. 531, 18, p. 2109-2120 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

The TgF344-AD rat: behavioral and proteomic changes associated with aging and protein expression in a transgenic rat model of Alzheimer's disease

Bac, B., Hicheri, C., Weiss, C., Buell, A., Vilcek, N., Spaeni, C., Geula, C., Savas, J. N. & Disterhoft, J. F., Mar 2023, In: Neurobiology of Aging. 123, p. 98-110 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Treatment-induced neural reorganization in aphasia is language-domain specific: Evidence from a large-scale fMRI study

Barbieri, E., Thompson, C. K., Higgins, J., Caplan, D., Kiran, S., Rapp, B. & Parrish, T., Feb 2023, In: Cortex. 159, p. 75-100 26 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2022

Alzheimer's polygenic hazard score in SuperAgers: SuperGenes or SuperResilience?

Spencer, B. E., Banks, S. J., Dale, A. M., Brewer, J. B., Makowski-Woidan, B., Weintraub, S., Mesulam, M. M., Geula, C. & Rogalski, E., 2022, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 8, 1, e12321.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

A Process Evaluation of Developing Older Adult Research Advisory Boards in Long-term Care Settings

Berman, R. L. H., Abbott, K. M., Cohen, M. A., Yoshizaki-Gibbons, H. M., McGaffigan, E., Morhardt, D. J., Straker, J. K., Eisenstein, A. R. & Lessem, R., Sep 1 2022, In: Progress in Community Health Partnerships: Research, Education, and Action. 16, 3, p. 393-400 8 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

ARMADA: Assessing reliable measurement in Alzheimer’s disease and cognitive aging project methods

Weintraub, S., Karpouzian-Rogers, T., Peipert, J. D., Nowinski, C., Slotkin, J., Wortman, K., Ho, E., Rogalski, E., Carlsson, C., Giordani, B., Goldstein, F., Lucas, J., Manly, J. J., Rentz, D., Salmon, D., Snitz, B., Dodge, H. H., Riley, M., Eldes, F. & Ustsinovich, V. & 1 others, Gershon, R., Aug 2022, In: Alzheimer's and Dementia. 18, 8, p. 1449-1460 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Communication Bridge™-2 (CB2): an NIH Stage 2 randomized control trial of a speech-language intervention for communication impairments in individuals with mild to moderate primary progressive aphasia

Roberts, A. C., Rademaker, A. W., Salley, E. A., Mooney, A., Morhardt, D., Fried-Oken, M., Weintraub, S., Mesulam, M. & Rogalski, E., Dec 2022, In: Trials. 23, 1, 487.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Cortical and subcortical pathological burden and neuronal loss in an autopsy series of FTLD-TDP-Type C

Kawles, A., Nishihira, Y., Feldman, A., Gill, N., Minogue, G., Keszycki, R., Coventry, C., Spencer, C., Lilek, J., Ajroud, K., Coppola, G., Rademakers, R., Rogalski, E., Weintraub, S., Zhang, H., Flanagan, M. E., Bigio, E. H., Mesulam, M. M., Geula, C. & Mao, Q. & 1 others, Gefen, T., Mar 1 2022, In: Brain. 145, 3, p. 1069-1078 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology

Martersteck, A., Ayala, I., Ohm, D. T., Spencer, C., Coventry, C., Weintraub, S., Bigio, E. H., Mesulam, M. M., Geula, C. & Rogalski, E., Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 111.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Integrity of Neuronal Size in the Entorhinal Cortex Is a Biological Substrate of Exceptional Cognitive Aging

Nassif, C., Kawles, A., Ayala, I., Minogue, G., Gill, N. P., Shepard, R. A., Zouridakis, A., Keszycki, R., Zhang, H., Mao, Q., Flanagan, M. E., Bigio, E. H., Mesulam, M. M., Rogalski, E., Geula, C. & Gefen, T., Nov 9 2022, In: Journal of Neuroscience. 42, 45, p. 8587-8594 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Neuropathological fingerprints of survival, atrophy and language in primary progressive aphasia

Mesulam, M. M., Coventry, C. A., Bigio, E. H., Sridhar, J., Gill, N., Fought, A. J., Zhang, H., Thompson, C. K., Geula, C., Gefen, T., Flanagan, M. E., Mao, Q., Weintraub, S. & Rogalski, E. J., Jun 1 2022, In: Brain. 145, 6, p. 2133-2148 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Propagation of TDP-43 proteinopathy in neurodegenerative disorders

Keszycki, R., Jamshidi, P., Kawles, A., Minogue, G., Flanagan, M. E., Zaccard, C. R., Mesulam, M. M., Gefen, T. & Geula, C., Jul 2022, In: Neural Regeneration Research. 17, 7, p. 1498-1500 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Resistance of Basal Forebrain Cholinergic Neurons to TDP-43 Proteinopathy in Primary Progressive Aphasia

Dunlop, S. R., Ayala, I., Spencer, C., Flanagan, M. E., Mesulam, M. M., Gefen, T. & Geula, C., Nov 1 2022, In: Journal of neuropathology and experimental neurology. 81, 11, p. 910-919 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Results of a Randomized Trial Testing the Efficacy of Tele-Savvy, an Online Synchronous/Asynchronous Psychoeducation Program for Family Caregivers of Persons Living with Dementia

Hepburn, K., Nocera, J., Higgins, M., Epps, F., Brewster, G. S., Lindauer, A., Morhardt, D., Shah, R., Bonds, K., Nash, R. & Griffiths, P. C., May 1 2022, In: Gerontologist. 62, 4, p. 616-628 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Stressors and Acceptability of Services among Black Caregivers of Persons with Memory Problems

Ejem, D., Atkins, G. C., Perkins, M., Morhardt, D. J., Williams, I. C., Cothran, F. A., Epps, F., Scott, C., Mittelman, M. & Clay, O. J., Jun 2022, In: Journal of Gerontological Nursing. 48, 6, p. 13-18 6 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2021

Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer’s disease

Ohm, D. T., Fought, A. J., Martersteck, A., Coventry, C., Sridhar, J., Gefen, T., Weintraub, S., Bigio, E., Mesulam, M. M., Rogalski, E. & Geula, C., Jan 2021, In: Brain Pathology. 31, 1, p. 189-204 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds

Griswold, A. J., Celis, K., Bussies, P. L., Rajabli, F., Whitehead, P. L., Hamilton-Nelson, K. L., Beecham, G. W., Dykxhoorn, D. M., Nuytemans, K., Wang, L., Gardner, O. K., Dorfsman, D. A., Bigio, E. H., Mesulam, M. M., Weintraub, S., Geula, C., Gearing, M., McGrath-Martinez, E., Dalgard, C. L. & Scott, W. K. & 4 others, Haines, J. L., Pericak-Vance, M. A., Young, J. I. & Vance, J. M., Jul 2021, In: Alzheimer's and Dementia. 17, 7, p. 1179-1188 10 p.

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Memory Resilience in Alzheimer Disease With Primary Progressive Aphasia

Mesulam, M. M., Coventry, C., Kuang, A., Bigio, E. H., Mao, Q., Flanagan, M. E., Gefen, T., Sridhar, J., Geula, C., Zhang, H., Weintraub, S. & Rogalski, E. J., Feb 9 2021, In: Neurology. 96, 6, p. E916-E925

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Paucity of Entorhinal Cortex Pathology of the Alzheimer's Type in SuperAgers with Superior Memory Performance

Gefen, T., Kawles, A., Makowski-Woidan, B., Engelmeyer, J., Ayala, I., Abbassian, P., Zhang, H., Weintraub, S., Flanagan, M. E., Mao, Q., Bigio, E. H., Rogalski, E., Mesulam, M. M. & Geula, C., Jul 1 2021, In: Cerebral Cortex. 31, 7, p. 3177-3183 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway

Jiang, S., Maphis, N. M., Binder, J., Chisholm, D., Weston, L., Duran, W., Peterson, C., Zimmerman, A., Mandell, M. A., Jett, S. D., Bigio, E., Geula, C., Mellios, N., Weick, J. P., Rosenberg, G. A., Latz, E., Heneka, M. T. & Bhaskar, K., Sep 21 2021, In: Cell reports. 36, 12, 109720.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

2020

Calbindin-D_28K, parvalbumin, and calretinin in young and aged human locus coeruleus

Lamerand, S., Shahidehpour, R., Ayala, I., Gefen, T., Mesulam, M. M., Bigio, E. & Geula, C., Oct 2020, In: Neurobiology of Aging. 94, p. 243-249 7 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Distribution of tdp-43 pathology in hippocampal synaptic relays suggests transsynaptic propagation in frontotemporal lobar degeneration

Jamshidi, P., Kim, G., Shahidehpour, R. K., Bolbolan, K., Gefen, T., Bigio, E. H., Mesulam, M. M. & Geula, C., 2020, In: Journal of neuropathology and experimental neurology. 79, 6, p. 585-591 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Neuropathologic basis of in vivo cortical atrophy in the aphasic variant of Alzheimer's disease

Ohm, D. T., Fought, A. J., Rademaker, A., Kim, G., Sridhar, J., Coventry, C., Gefen, T., Weintraub, S., Bigio, E., Mesulam, M. M., Rogalski, E. & Geula, C., Mar 1 2020, In: Brain Pathology. 30, 2, p. 332-344 13 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2019

Activated microglia in cortical white matter across cognitive aging trajectories

Gefen, T., Kim, G., Bolbolan, K., Geoly, A., Ohm, D., Oboudiyat, C., Shahidehpour, R., Rademaker, A., Weintraub, S., Bigio, E. H., Marsel Mesulam, M., Rogalski, E. & Geula, C., 2019, In: Frontiers in Aging Neuroscience. 11, MAY, 94.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Can Persons with Dementia Meaningfully Participate in Advance Care Planning Discussions? A Mixed-Methods Study of SPIRIT

Song, M. K., Ward, S. E., Hepburn, K., Paul, S., Kim, H., Shah, R. C., Morhardt, D. J., Medders, L., Lah, J. J. & Clevenger, C. C., Nov 2019, In: Journal of palliative medicine. 22, 11, p. 1410-1416 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first 10 cases

Rogalski, E., Gefen, T., Mao, Q., Connelly, M., Weintraub, S., Geula, C., Bigio, E. H. & Mesulam, M. M., May 2019, In: Hippocampus. 29, 5, p. 458-467 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Cortical cholinergic denervation in primary progressive aphasia with Alzheimer pathology

Mesulam, M. M., Lalehzari, N., Rahmani, F., Ohm, D., Shahidehpour, R., Kim, G., Gefen, T., Weintraub, S., Bigio, E. & Geula, C., Apr 2 2019, In: Neurology. 92, 14, p. E1580-E1588

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Development of a Psycho-Educational Support Program for Individuals with Primary Progressive Aphasia and their Care-Partners

Morhardt, D. J., O’Hara, M. C., Zachrich, K., Wieneke, C. & Rogalski, E. J., May 1 2019, In: Dementia. 18, 4, p. 1310-1327 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Pottier, C., Ren, Y., Perkerson, R. B., Baker, M., Jenkins, G. D., van Blitterswijk, M., DeJesus-Hernandez, M., van Rooij, J. G. J., Murray, M. E., Christopher, E., McDonnell, S. K., Fogarty, Z., Batzler, A., Tian, S., Vicente, C. T., Matchett, B., Karydas, A. M., Hsiung, G. Y. R., Seelaar, H. & Mol, M. O. & 85 others, Finger, E. C., Graff, C., Öijerstedt, L., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Prudlo, J., Rizzu, P., Simon-Sanchez, J., Edbauer, D., Roeber, S., Diehl-Schmid, J., Evers, B. M., King, A., Mesulam, M. M., Weintraub, S., Geula, C., Bieniek, K. F., Petrucelli, L., Ahern, G. L., Reiman, E. M., Woodruff, B. K., Caselli, R. J., Huey, E. D., Farlow, M. R., Grafman, J., Mead, S., Grinberg, L. T., Spina, S., Grossman, M., Irwin, D. J., Lee, E. B., Suh, E. R., Snowden, J., Mann, D., Ertekin-Taner, N., Uitti, R. J., Wszolek, Z. K., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Hodges, J. R., Piguet, O., Geier, E. G., Yokoyama, J. S., Rissman, R. A., Rogaeva, E., Keith, J., Zinman, L., Tartaglia, M. C., Cairns, N. J., Cruchaga, C., Ghetti, B., Kofler, J., Lopez, O. L., Beach, T. G., Arzberger, T., Herms, J., Honig, L. S., Vonsattel, J. P., Halliday, G. M., Kwok, J. B., White, C. L., Gearing, M., Glass, J., Rollinson, S., Pickering-Brown, S., Rohrer, J. D., Trojanowski, J. Q., Van Deerlin, V., Bigio, E. H., Troakes, C., Al-Sarraj, S., Asmann, Y., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Seeley, W. W., Mackenzie, I. R. A., van Swieten, J. C., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jun 1 2019, In: Acta Neuropathologica. 137, 6, p. 879-899 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Morphology and Distribution of TDP-43 Pre-inclusions in Primary Progressive Aphasia

Kim, G., Bolbolan, K., Shahidehpour, R., Jamshidi, P., Gefen, T., Ayala, I. A., Weintraub, S., Bigio, E. H., Mesulam, M. M. & Geula, C., Mar 1 2019, In: Journal of neuropathology and experimental neurology. 78, 3, p. 229-237 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Prominent microglial activation in cortical white matter is selectively associated with cortical atrophy in primary progressive aphasia

Ohm, D. T., Kim, G., Gefen, T., Rademaker, A., Weintraub, S., Bigio, E. H., Mesulam, M. M., Rogalski, E. & Geula, C., Apr 2019, In: Neuropathology and Applied Neurobiology. 45, 3, p. 216-229 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Word comprehension in temporal cortex and Wernicke area: A PPA perspective

Mesulam, M. M., Rader, B. M., Sridhar, J., Nelson, M. J., Hyun, J., Rademaker, A., Geula, C., Bigio, E. H., Thompson, C. K., Gefen, T. D., Weintraub, S. & Rogalski, E. J., Jan 15 2019, In: Neurology. 92, 3, p. E224-E233

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

2018

Associations of MAP2K3 gene variants with superior memory in SuperAgers

for the Alzheimer's Disease Neuroimaging Initiative, May 29 2018, In: Frontiers in Aging Neuroscience. 10, MAY, 155.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Asymmetric TDP pathology in primary progressive aphasia with right hemisphere language dominance

Kim, G., Vahedi, S., Gefen, T., Weintraub, S., Bigio, E. H., Mesulam, M. M. & Geula, C., Jan 30 2018, In: Neurology. 90, 5, p. e396-e403

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Atrophy and microglial distribution in primary progressive aphasia with transactive response DNA-binding protein-43 kDa

Kim, G., Bolbolan, K., Gefen, T., Weintraub, S., Bigio, E. H., Rogalski, E., Mesulam, M. M. & Geula, C., Jun 2018, In: Annals of neurology. 83, 6, p. 1096-1104 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Combined pathologies in FTLD-TDP types A and C

Gefen, T., Ahmadian, S. S., Mao, Q., Kim, G., Seckin, M., Bonakdarpour, B., Ramos, E. M., Coppola, G., Rademakers, R., Rogalski, E., Rademaker, A., Weintraub, S., Mesulam, M. M., Geula, C. & Bigio, E. H., May 1 2018, In: Journal of neuropathology and experimental neurology. 77, 5, p. 405-412 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Differential neurotoxicity related to tetracycline transactivator and TDP-43 expression in conditional TDP-43 mouse model of frontotemporal lobar degeneration

Kukreja, L., Shahidehpour, R., Kim, G., Keegan, J., Sadleir, K. R., Russell, T., Csernansky, J., Mesulam, M., Vassar, R. J., Wang, L., Dong, H. & Geula, C., Jul 4 2018, In: Journal of Neuroscience. 38, 27, p. 6045-6062 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

Gabrusiewicz, K., Li, X., Wei, J., Hashimoto, Y., Marisetty, A. L., Ott, M., Wang, F., Hawke, D., Yu, J., Healy, L. M., Hossain, A., Akers, J. C., Maiti, S. N., Yamashita, S., Shimizu, Y., Dunner, K., Zal, M. A., Burks, J. K., Gumin, J. & Nwajei, F. & 15 others, Rezavanian, A., Zhou, S., Rao, G., Sawaya, R., Fuller, G. N., Huse, J. T., Antel, J. P., Li, S., Cooper, L., Sulman, E. P., Chen, C., Geula, C., Kalluri, R., Zal, T. & Heimberger, A. B., Apr 3 2018, In: OncoImmunology. 7, 4, e1412909.

Research output: Contribution to journal › Article › peer-review

Open Access

255 Scopus citations

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

Pottier, C., Zhou, X., Perkerson, R. B., Baker, M., Jenkins, G. D., Serie, D. J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., Zulaica, M., Moreno, F., Le Ber, I., Pasquier, F., Hannequin, D., Sánchez-Valle, R., Antonell, A., Lladó, A., Parsons, T. M. & Finch, N. C. A. & 113 others, Finger, E. C., Lippa, C. F., Huey, E. D., Neumann, M., Heutink, P., Synofzik, M., Wilke, C., Rissman, R. A., Slawek, J., Sitek, E., Johannsen, P., Nielsen, J. E., Ren, Y., van Blitterswijk, M., DeJesus-Hernandez, M., Christopher, E., Murray, M. E., Bieniek, K. F., Evers, B. M., Ferrari, C., Rollinson, S., Richardson, A., Scarpini, E., Fumagalli, G. G., Padovani, A., Hardy, J., Momeni, P., Ferrari, R., Frangipane, F., Maletta, R., Anfossi, M., Gallo, M., Petrucelli, L., Suh, E. R., Lopez, O. L., Wong, T. H., van Rooij, J. G. J., Seelaar, H., Mead, S., Caselli, R. J., Reiman, E. M., Noel Sabbagh, M., Kjolby, M., Nykjaer, A., Karydas, A. M., Boxer, A. L., Grinberg, L. T., Grafman, J., Spina, S., Oblak, A., Mesulam, M. M., Weintraub, S., Geula, C., Hodges, J. R., Piguet, O., Brooks, W. S., Irwin, D. J., Trojanowski, J. Q., Lee, E. B., Josephs, K. A., Parisi, J. E., Ertekin-Taner, N., Knopman, D. S., Nacmias, B., Piaceri, I., Bagnoli, S., Sorbi, S., Gearing, M., Glass, J., Beach, T. G., Black, S. E., Masellis, M., Rogaeva, E., Vonsattel, J. P., Honig, L. S., Kofler, J., Bruni, A. C., Snowden, J., Mann, D., Pickering-Brown, S., Diehl-Schmid, J., Winkelmann, J., Galimberti, D., Graff, C., Öijerstedt, L., Troakes, C., Al-Sarraj, S., Cruchaga, C., Cairns, N. J., Rohrer, J. D., Halliday, G. M., Kwok, J. B., van Swieten, J. C., White, C. L., Ghetti, B., Murell, J. R., Mackenzie, I. R. A., Hsiung, G. Y. R., Borroni, B., Rossi, G., Tagliavini, F., Wszolek, Z. K., Petersen, R. C., Bigio, E. H., Grossman, M., Van Deerlin, V. M., Seeley, W. W., Miller, B. L., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W., Biernacka, J. M. & Rademakers, R., Jun 2018, In: The Lancet Neurology. 17, 6, p. 548-558 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

90 Scopus citations

SPIRIT advance care planning intervention in early stage dementias: An NIH stage I behavioral intervention development trial

Song, M. K., Ward, S. E., Hepburn, K., Paul, S., Shah, R. C. & Morhardt, D. J., Aug 2018, In: Contemporary Clinical Trials. 71, p. 55-62 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Mesulam Center for Cognitive Neurology and Alzheimers Disease

Research Output

Search results